What are the genomic drivers of the rapid evolution of PRDM9?

Trends in Genetics

Volumn 27, Issue 5, 2011, Pages 165-171

  Ponting, Chris P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PR DOMAIN CONTAINING PROTEIN 9; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ALLELE; AMINO ACID SEQUENCE; CHROMOSOME ANALYSIS; CHROMOSOME POSITIONING; COPY NUMBER VARIATION; DNA BINDING; GENE REARRANGEMENT; GENETIC RECOMBINATION; GENETIC SELECTION; GENOMICS; HUMAN; MEIOSIS; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEQUENCE ANALYSIS; SPECIES DIFFERENTIATION;

ANIMALS; EVOLUTION, MOLECULAR; GENETIC SPECIATION; GENOME; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; PHYLOGENY; TIME FACTORS;

ANIMALIA; MAMMALIA;

EID: 79955095683     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2011.02.001     Document Type: Review

References (48)

1. Jiang G.L., Huang S. The yin-yang of PR-domain family genes in tumorigenesis. Histol. Histopathol. 2000, 15:109-117.
2. Jenuwein T., et al. SET domain proteins modulate chromatin domains in eu- and heterochromatin. Cell. Mol. Life Sci. 1998, 54:80-93.
3. Rea S., et al. Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 2000, 406:593-599.
4. Fumasoni I., et al. Family expansion and gene rearrangements contributed to the functional specialization of PRDM genes in vertebrates. BMC Evol. Biol. 2007, 7:187.
5. Birtle Z., Ponting C.P. Meisetz and the birth of the KRAB motif. Bioinformatics 2006, 22:2841-2845.
6. Lim F.L., et al. A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas. Oncogene 1998, 17:2013-2018.
7. Oliver P.L., et al. Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa. PLoS Genet. 2009, 5:e1000753.
8. Hayashi K., et al. A histone H3 methyltransferase controls epigenetic events required for meiotic prophase. Nature 2005, 438:374-378.
9. Wolfe S.A., et al. DNA recognition by Cys2His2 zinc finger proteins. Annu. Rev. Biophys. Biomol. Struct. 2000, 29:183-212.
10. Rosenfeld R., Margalit H. Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. J. Biomol. Struct. Dyn. 1993, 11:557-570.
11. Baudat F., et al. PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Science 2010, 327:836-840.
12. Myers S., et al. A fine-scale map of recombination rates and hotspots across the human genome. Science 2005, 310:321-324.
13. Lichten M., Goldman A.S. Meiotic recombination hotspots. Annu. Rev. Genet. 1995, 29:423-444.
14. Myers S., et al. A common sequence motif associated with recombination hot spots and genome instability in humans. Nat. Genet. 2008, 40:1124-1129.
15. Ptak S.E., et al. Fine-scale recombination patterns differ between chimpanzees and humans. Nat. Genet. 2005, 37:429-434.
16. Winckler W., et al. Comparison of fine-scale recombination rates in humans and chimpanzees. Science 2005, 308:107-111.
17. Myers S., et al. Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination. Science 2010, 327:876-879.
18. Mihola O., et al. A mouse speciation gene encodes a meiotic histone H3 methyltransferase. Science 2009, 323:373-375.
19. Parvanov E.D., et al. Prdm9 controls activation of mammalian recombination hotspots. Science 2010, 327:835.
20. Sandovici I., Sapienza C. PRDM9 sticks its zinc fingers into recombination hotspots and between species. F1000 Biol. Rep. 2010, 2:37.
21. McVean G., Myers S. PRDM9 marks the spot. Nat. Genet. 2010, 42:821-822.
22. Hochwagen A., Marais G.A. Meiosis: a PRDM9 guide to the hotspots of recombination. Curr. Biol. 2010, 20:R271-274.
23. Neale M.J. PRDM9 points the zinc finger at meiotic recombination hotspots. Genome Biol. 2010, 11:104.
24. Wahls W.P., Davidson M.K. Discrete DNA sites regulate global distribution of meiotic recombination. Trends Genet. 2010, 26:202-208.
25. Thomas J.H., et al. Extraordinary molecular evolution in the PRDM9 fertility gene. PLoS ONE 2009, 4:e8505.
26. Vignaud P., et al. Geology and palaeontology of the Upper Miocene Toros-Menalla hominid locality. Chad. Nat. 2002, 418:152-155.
27. Pavletich N.P., Pabo C.O. Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1Å. Science 1991, 252:809-817.
28. Choo Y., Klug A. Physical basis of a protein-DNA recognition code. Curr. Opin. Struct. Biol. 1997, 7:117-125.
29. Smith G.P. Evolution of repeated DNA sequences by unequal crossover. Science 1976, 191:528-535.
30. Szostak J.W., et al. The double-strand-break repair model for recombination. Cell 1983, 33:25-35.
31. Berg I.L., et al. PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans. Nat. Genet. 2010, 42:859-863.
32. Dover G.A., et al. Molecular drive. Science 1982, 218:1069.
33. Berg I.L., et al. PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans. Nat. Genet. 2010, 42:859-863.
34. Kong A., et al. Fine-scale recombination rate differences between sexes, populations and individuals. Nature 2010, 467:1099-1103.
35. Hey J. What's so hot about recombination hotspots?. PLoS Biol. 2004, 2:e190.
36. Pineda-Krch M., Redfield R.J. Persistence and loss of meiotic recombination hotspots. Genetics 2005, 169:2319-2333.
37. Boulton A., et al. The hotspot conversion paradox and the evolution of meiotic recombination. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:8058-8063.
38. Jeffreys A.J., Neumann R. The rise and fall of a human recombination hot spot. Nat. Genet. 2009, 41:625-629.
39. Rouyer F., et al. A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes. Nature 1986, 319:291-295.
40. Perry J., et al. A short pseudoautosomal region in laboratory mice. Genome Res. 2001, 11:1826-1832.
41. Otto S.P., Barton N.H. The evolution of recombination: removing the limits to natural selection. Genetics 1997, 147:879-906.
42. Hill W.G., Robertson A. The effect of linkage on limits to artificial selection. Genet. Res. 1966, 8:269-294.
43. Felsenstein J. The evolutionary advantage of recombination. Genetics 1974, 78:737-756.
44. Irie S., et al. Single-nucleotide polymorphisms of the PRDM9 (MEISETZ) gene in patients with nonobstructive azoospermia. J. Androl. 2009, 30:426-431.
45. Mayr E. Systematics and the Origin of Species, From the Viewpoint of a Zoologist 1942, Harvard University Press.
46. Coop G., Myers S.R. Live hot, die young: transmission distortion in recombination hotspots. PLoS Genet. 2007, 3:e35.
47. Chimpanzee Sequencing and Analysis Consortium Initial sequence of the chimpanzee genome and comparison with the human genome. Nature 2005, 437:69-87.
48. Pollard K.S., et al. Forces shaping the fastest evolving regions in the human genome. PLoS Genet. 2006, 2:e168.