-
1
-
-
0013834960
-
Deletion of short arms of chromosome 4-5 in a child with defects of midline fusion
-
Hirschhorn, K., Cooper, H. L., and Firschein, I. L. (1965) Deletion of short arms of chromosome 4-5 in a child with defects of midline fusion. Humangenetik 1, 479-482
-
(1965)
Humangenetik
, vol.1
, pp. 479-482
-
-
Hirschhorn, K.1
Cooper, H.L.2
Firschein, I.L.3
-
2
-
-
0033200284
-
2+-binding protein, flanks the Wolf-Hirschhorn syndrome (WHS) critical region and is deleted in most WHS patients
-
2+-binding protein, flanks the Wolf-Hirschhorn syndrome (WHS) critical region and is deleted in most WHS patients. Genomics 60, 218-225
-
(1999)
Genomics
, vol.60
, pp. 218-225
-
-
Endele, S.1
Fuhry, M.2
Pak, S.J.3
Zabel, B.U.4
Winterpacht, A.5
-
3
-
-
0347359154
-
LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial protein
-
Schlickum, S., Moghekar, A., Simpson, J. C., Steglich, C., O'Brien, R. J., Winterpacht, A., and Endele, S. U. (2004) LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial protein. Genomics 83, 254-261
-
(2004)
Genomics
, vol.83
, pp. 254-261
-
-
Schlickum, S.1
Moghekar, A.2
Simpson, J.C.3
Steglich, C.4
O'brien, R.J.5
Winterpacht, A.6
Endele, S.U.7
-
4
-
-
80051946060
-
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
-
Baughman, J. M., Perocchi, F., Girgis, H. S., Plovanich, M., Belcher-Timme, C. A., Sancak, Y., Bao, X. R., Strittmatter, L., Goldberger, O., Bogorad, R. L., Koteliansky, V., and Mootha, V. K. (2011) Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 476, 341-345
-
(2011)
Nature
, vol.476
, pp. 341-345
-
-
Baughman, J.M.1
Perocchi, F.2
Girgis, H.S.3
Plovanich, M.4
Belcher-Timme, C.A.5
Sancak, Y.6
Bao, X.R.7
Strittmatter, L.8
Goldberger, O.9
Bogorad, R.L.10
Koteliansky, V.11
Mootha, V.K.12
-
5
-
-
80051936634
-
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
-
De Stefani, D., Raffaello, A., Teardo, E., Szabo, I., and Rizzuto, R. (2011) A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 476, 336-340
-
(2011)
Nature
, vol.476
, pp. 336-340
-
-
De Stefani, D.1
Raffaello, A.2
Teardo, E.3
Szabo, I.4
Rizzuto, R.5
-
6
-
-
77956928316
-
2+ uptake
-
2+ uptake. Nature 467, 291-296
-
(2010)
Nature
, vol.467
, pp. 291-296
-
-
Perocchi, F.1
Gohil, V.M.2
Girgis, H.S.3
Bao, X.R.4
McCombs, J.E.5
Palmer, A.E.6
Mootha, V.K.7
-
7
-
-
84868027665
-
2+ uptake that regulates cell survival
-
2+ uptake that regulates cell survival. Cell 151, 630-644
-
(2012)
Cell
, vol.151
, pp. 630-644
-
-
Mallilankaraman, K.1
Doonan, P.2
Cardenas, C.3
Chandramoorthy, H.C.4
Muller, M.5
Miller, R.6
Hoffman, N.E.7
Gandhirajan, R.K.8
Molgo, J.9
Birnbaum, M.J.10
Rothberg, B.S.11
Mak, D.O.12
Foskett, J.K.13
Madesh, M.14
-
8
-
-
84871841837
-
2+ uptake that regulates cellular metabolism
-
2+ uptake that regulates cellular metabolism. Nat. Cell Biol. 15, 123
-
(2012)
Nat. Cell Biol.
, vol.15
, pp. 123
-
-
Mallilankaraman, K.1
Cardenas, C.2
Doonan, P.J.3
Chandramoorthy, H.C.4
Irrinki, K.M.5
Golenar, T.6
Csordas, G.7
Madireddi, P.8
Yang, J.9
Muller, M.10
Miller, R.11
Kolesar, J.E.12
Molgo, J.13
Kaufman, B.14
Hajnoczky, G.15
Foskett, J.K.16
Madesh, M.17
-
9
-
-
84873572862
-
MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling
-
Plovanich, M., Bogorad, R. L., Sancak, Y., Kamer, K. J., Strittmatter, L., Li, A. A., Girgis, H. S., Kuchimanchi, S., De Groot, J., Speciner, L., Taneja, N., Oshea, J., Koteliansky, V., and Mootha, V. K. (2013) MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling. PLoS One 8, e55785
-
(2013)
PLoS One
, vol.8
, pp. e55785
-
-
Plovanich, M.1
Bogorad, R.L.2
Sancak, Y.3
Kamer, K.J.4
Strittmatter, L.5
Li, A.A.6
Girgis, H.S.7
Kuchimanchi, S.8
De Groot, J.9
Speciner, L.10
Taneja, N.11
Oshea, J.12
Koteliansky, V.13
Mootha, V.K.14
-
10
-
-
84883286784
-
The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit
-
Raffaello, A., De Stefani, D., Sabbadin, D., Teardo, E., Merli, G., Picard, A., Checchetto, V., Moro, S., Szabo, I., and Rizzuto, R. (2013) The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit. EMBO J. 32, 2362-2376
-
(2013)
EMBO J.
, vol.32
, pp. 2362-2376
-
-
Raffaello, A.1
De Stefani, D.2
Sabbadin, D.3
Teardo, E.4
Merli, G.5
Picard, A.6
Checchetto, V.7
Moro, S.8
Szabo, I.9
Rizzuto, R.10
-
11
-
-
84890116192
-
EMRE is an essential component of the mitochondrial calcium uniporter complex
-
Sancak, Y., Markhard, A. L., Kitami, T., Kovacs-Bogdan, E., Kamer, K. J., Udeshi, N. D., Carr, S. A., Chaudhuri, D., Clapham, D. E., Li, A. A., Calvo, S. E., Goldberger, O., and Mootha, V. K. (2013) EMRE is an essential component of the mitochondrial calcium uniporter complex. Science 342, 1379-1382
-
(2013)
Science
, vol.342
, pp. 1379-1382
-
-
Sancak, Y.1
Markhard, A.L.2
Kitami, T.3
Kovacs-Bogdan, E.4
Kamer, K.J.5
Udeshi, N.D.6
Carr, S.A.7
Chaudhuri, D.8
Clapham, D.E.9
Li, A.A.10
Calvo, S.E.11
Goldberger, O.12
Mootha, V.K.13
-
12
-
-
76249133414
-
2+ exchange
-
2+ exchange. Proc. Natl. Acad. Sci. U. S. A. 107, 436-441
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 436-441
-
-
Palty, R.1
Silverman, W.F.2
Hershfinkel, M.3
Caporale, T.4
Sensi, S.L.5
Parnis, J.6
Nolte, C.7
Fishman, D.8
Shoshan-Barmatz, V.9
Herrmann, S.10
Khananshvili, D.11
Sekler, I.12
-
13
-
-
84896262743
-
2+ uptake, interacts with MCU, and induces oxidative stress-mediated cell death
-
2+ uptake, interacts with MCU, and induces oxidative stress-mediated cell death. Mol. Biol. Cell 25, 936-947
-
(2014)
Mol. Biol. Cell
, vol.25
, pp. 936-947
-
-
Hoffman, N.E.1
Chandramoorthy, H.C.2
Shanmughapriya, S.3
Zhang, X.Q.4
Vallem, S.5
Doonan, P.J.6
Malliankaraman, K.7
Guo, S.8
Rajan, S.9
Elrod, J.W.10
Koch, W.J.11
Cheung, J.Y.12
Madesh, M.13
-
14
-
-
15844375853
-
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
-
Baines, C. P., Kaiser, R. A., Purcell, N. H., Blair, N. S., Osinska, H., Hambleton, M. A., Brunskill, E. W., Sayen, M. R., Gottlieb, R. A., Dorn, G. W., Robbins, J., and Molkentin, J. D. (2005) Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434, 658-662
-
(2005)
Nature
, vol.434
, pp. 658-662
-
-
Baines, C.P.1
Kaiser, R.A.2
Purcell, N.H.3
Blair, N.S.4
Osinska, H.5
Hambleton, M.A.6
Brunskill, E.W.7
Sayen, M.R.8
Gottlieb, R.A.9
Dorn, G.W.10
Robbins, J.11
Molkentin, J.D.12
-
15
-
-
15844407874
-
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
-
Nakagawa, T., Shimizu, S., Watanabe, T., Yamaguchi, O., Otsu, K., Yamagata, H., Inohara, H., Kubo, T., and Tsujimoto, Y. (2005) Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434, 652-658
-
(2005)
Nature
, vol.434
, pp. 652-658
-
-
Nakagawa, T.1
Shimizu, S.2
Watanabe, T.3
Yamaguchi, O.4
Otsu, K.5
Yamagata, H.6
Inohara, H.7
Kubo, T.8
Tsujimoto, Y.9
-
16
-
-
0030826778
-
Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury
-
Halestrap, A. P., Connern, C. P., Griffiths, E. J., and Kerr, P. M. (1997) Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury. Mol. Cell. Biochem. 174, 167-172
-
(1997)
Mol. Cell. Biochem.
, vol.174
, pp. 167-172
-
-
Halestrap, A.P.1
Connern, C.P.2
Griffiths, E.J.3
Kerr, P.M.4
-
17
-
-
15844404722
-
Biochemistry: A pore way to die
-
Halestrap, A. (2005) Biochemistry: a pore way to die. Nature 434, 578-579
-
(2005)
Nature
, vol.434
, pp. 578-579
-
-
Halestrap, A.1
-
18
-
-
21244446551
-
Properties of the permeability transition pore in mitochondria devoid of cyclophilin D
-
Basso, E., Fante, L., Fowlkes, J., Petronilli, V., Forte, M. A., and Bernardi, P. (2005) Properties of the permeability transition pore in mitochondria devoid of cyclophilin D. J. Biol. Chem. 280, 18558-18561
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18558-18561
-
-
Basso, E.1
Fante, L.2
Fowlkes, J.3
Petronilli, V.4
Forte, M.A.5
Bernardi, P.6
-
19
-
-
77951920370
-
The cardiac mitochondrion: Nexus of stress
-
Baines, C. P. (2010) The cardiac mitochondrion: nexus of stress. Annu. Rev. Physiol. 72, 61-80
-
(2010)
Annu. Rev. Physiol.
, vol.72
, pp. 61-80
-
-
Baines, C.P.1
-
22
-
-
3142664727
-
The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome
-
Nowikovsky, K., Froschauer, E. M., Zsurka, G., Samaj, J., Reipert, S., Kolisek, M., Wiesenberger, G., and Schweyen, R. J. (2004) The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome. J. Biol. Chem. 279, 30307-30315
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 30307-30315
-
-
Nowikovsky, K.1
Froschauer, E.M.2
Zsurka, G.3
Samaj, J.4
Reipert, S.5
Kolisek, M.6
Wiesenberger, G.7
Schweyen, R.J.8
-
23
-
-
77950650727
-
A Drosophila mutant of LETM1, a candidate gene for seizures in Wolf-Hirschhorn syndrome
-
McQuibban, A. G., Joza, N., Megighian, A., Scorzeto, M., Zanini, D., Reipert, S., Richter, C., Schweyen, R. J., and Nowikovsky, K. (2010) A Drosophila mutant of LETM1, a candidate gene for seizures in Wolf-Hirschhorn syndrome. Hum. Mol. Genet. 19, 987-1000
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 987-1000
-
-
McQuibban, A.G.1
Joza, N.2
Megighian, A.3
Scorzeto, M.4
Zanini, D.5
Reipert, S.6
Richter, C.7
Schweyen, R.J.8
Nowikovsky, K.9
-
24
-
-
84878961842
-
+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome
-
+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome. Proc. Natl. Acad. Sci. U. S. A. 110, E2249-E2254
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. E2249-E2254
-
-
Jiang, D.1
Zhao, L.2
Clish, C.B.3
Clapham, D.E.4
-
25
-
-
0031925889
-
Antibody deficiency in Wolf-Hirschhorn syndrome
-
Hanley-Lopez, J., Estabrooks, L. L., and Stiehm, R. (1998) Antibody deficiency in Wolf-Hirschhorn syndrome. J. Pediatr. 133, 141-143
-
(1998)
J. Pediatr.
, vol.133
, pp. 141-143
-
-
Hanley-Lopez, J.1
Estabrooks, L.L.2
Stiehm, R.3
-
26
-
-
84886416217
-
Inhibition of the cardiomyocytespecific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart
-
Vagnozzi, R. J., Gatto, G. J., Jr., Kallander, L. S., Hoffman, N. E., Mallilankaraman, K., Ballard, V. L., Lawhorn, B. G., Stoy, P., Philp, J., Graves, A. P., Naito, Y., Lepore, J. J., Gao, E., Madesh, M., and Force, T. (2013) Inhibition of the cardiomyocytespecific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart. Sci. Transl. Med. 5, 207ra141
-
(2013)
Sci. Transl. Med.
, vol.5
, pp. 207ra141
-
-
Vagnozzi, R.J.1
Gatto, G.J.2
Kallander, L.S.3
Hoffman, N.E.4
Mallilankaraman, K.5
Ballard, V.L.6
Lawhorn, B.G.7
Stoy, P.8
Philp, J.9
Graves, A.P.10
Naito, Y.11
Lepore, J.J.12
Gao, E.13
Madesh, M.14
Force, T.15
-
27
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini, L., Blomer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., and Trono, D. (1996) In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
Gage, F.H.6
Verma, I.M.7
Trono, D.8
-
28
-
-
84891011448
-
MICU1 motifs define mitochondrial calcium uniporter binding and activity
-
Hoffman, N. E., Chandramoorthy, H. C., Shamugapriya, S., Zhang, X., Rajan, S., Mallilankaraman, K., Gandhirajan, R. K., Vagnozzi, R. J., Ferrer, L. M., Sreekrishnanilayam, K., Natarajaseenivasan, K., Vallem, S., Force, T., Choi, E. T., Cheung, J. Y., and Madesh, M. (2013) MICU1 motifs define mitochondrial calcium uniporter binding and activity. Cell Rep. 5, 1576-1588
-
(2013)
Cell Rep.
, vol.5
, pp. 1576-1588
-
-
Hoffman, N.E.1
Chandramoorthy, H.C.2
Shamugapriya, S.3
Zhang, X.4
Rajan, S.5
Mallilankaraman, K.6
Gandhirajan, R.K.7
Vagnozzi, R.J.8
Ferrer, L.M.9
Sreekrishnanilayam, K.10
Natarajaseenivasan, K.11
Vallem, S.12
Force, T.13
Choi, E.T.14
Cheung, J.Y.15
Madesh, M.16
-
29
-
-
25444525139
-
Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and endothelial apoptosis
-
Madesh, M., Hawkins, B. J., Milovanova, T., Bhanumathy, C. D., Joseph, S. K., Ramachandrarao, S. P., Sharma, K., Kurosaki, T., and Fisher, A. B. (2005) Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and endothelial apoptosis. J. Cell Biol. 170, 1079-1090
-
(2005)
J. Cell Biol.
, vol.170
, pp. 1079-1090
-
-
Madesh, M.1
Hawkins, B.J.2
Milovanova, T.3
Bhanumathy, C.D.4
Joseph, S.K.5
Ramachandrarao, S.P.6
Sharma, K.7
Kurosaki, T.8
Fisher, A.B.9
-
30
-
-
66349101019
-
Execution of superoxide-induced cell death by the proapoptotic Bcl-2-related proteins Bid and Bak
-
Madesh, M., Zong, W. X., Hawkins, B. J., Ramasamy, S., Venkatachalam, T., Mukhopadhyay, P., Doonan, P. J., Irrinki, K. M., Rajesh, M., Pacher, P., and Thompson, C. B. (2009) Execution of superoxide-induced cell death by the proapoptotic Bcl-2-related proteins Bid and Bak. Mol. Cell. Biol. 29, 3099-3112
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3099-3112
-
-
Madesh, M.1
Zong, W.X.2
Hawkins, B.J.3
Ramasamy, S.4
Venkatachalam, T.5
Mukhopadhyay, P.6
Doonan, P.J.7
Irrinki, K.M.8
Rajesh, M.9
Pacher, P.10
Thompson, C.B.11
-
31
-
-
84896262743
-
2+ uptake, interacts with MCU, and induces oxidative stress-mediated cell death
-
2+ uptake, interacts with MCU, and induces oxidative stress-mediated cell death. Mol. Biol. Cell 25, 936-947
-
(2014)
Mol. Biol. Cell
, vol.25
, pp. 936-947
-
-
Hoffman, N.E.1
Chandramoorthy, H.C.2
Shanmughapriya, S.3
Zhang, X.Q.4
Vallem, S.5
Doonan, P.J.6
Malliankaraman, K.7
Guo, S.8
Rajan, S.9
Elrod, J.W.10
Koch, W.J.11
Cheung, J.Y.12
Madesh, M.13
-
32
-
-
1642540210
-
The mitochondrial calcium uniporter is a highly selective ion channel
-
Kirichok, Y., Krapivinsky, G., and Clapham, D. E. (2004) The mitochondrial calcium uniporter is a highly selective ion channel. Nature 427, 360-364
-
(2004)
Nature
, vol.427
, pp. 360-364
-
-
Kirichok, Y.1
Krapivinsky, G.2
Clapham, D.E.3
-
33
-
-
84871891066
-
Activity of the mitochondrial calcium uniporter varies greatly between tissues
-
Fieni, F., Lee, S. B., Jan, Y. N., and Kirichok, Y. (2012) Activity of the mitochondrial calcium uniporter varies greatly between tissues. Nat. Commun. 3, 1317
-
(2012)
Nat. Commun.
, vol.3
, pp. 1317
-
-
Fieni, F.1
Lee, S.B.2
Jan, Y.N.3
Kirichok, Y.4
-
34
-
-
84868629814
-
CaMKII determines mitochondrial stress responses in heart
-
Joiner, M. L., Koval, O. M., Li, J., He, B. J., Allamargot, C., Gao, Z., Luczak, E. D., Hall, D. D., Fink, B. D., Chen, B., Yang, J., Moore, S. A., Scholz, T. D., Strack, S., Mohler, P. J., Sivitz, W. I., Song, L. S., and Anderson, M. E. (2012) CaMKII determines mitochondrial stress responses in heart. Nature 491, 269-273
-
(2012)
Nature
, vol.491
, pp. 269-273
-
-
Joiner, M.L.1
Koval, O.M.2
Li, J.3
He, B.J.4
Allamargot, C.5
Gao, Z.6
Luczak, E.D.7
Hall, D.D.8
Fink, B.D.9
Chen, B.10
Yang, J.11
Moore, S.A.12
Scholz, T.D.13
Strack, S.14
Mohler, P.J.15
Sivitz, W.I.16
Song, L.S.17
Anderson, M.E.18
-
35
-
-
84870621600
-
2+ uptake that regulates cellular metabolism
-
2+ uptake that regulates cellular metabolism. Nat. Cell Biol. 14, 1336-1343
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 1336-1343
-
-
Mallilankaraman, K.1
Cardenas, C.2
Doonan, P.J.3
Chandramoorthy, H.C.4
Irrinki, K.M.5
Golenar, T.6
Csordas, G.7
Madireddi, P.8
Yang, J.9
Muller, M.10
Miller, R.11
Kolesar, J.E.12
Molgo, J.13
Kaufman, B.14
Hajnoczky, G.15
Foskett, J.K.16
Madesh, M.17
-
36
-
-
84896259360
-
TRPM2 channels protect against cardiac ischemia-reperfusion injury: Role of mitochondria
-
Miller, B. A., Hoffman, N. E., Merali, S., Zhang, X. Q., Wang, J., Rajan, S., Shanmughapriya, S., Gao, E., Barrero, C. A., Mallilankaraman, K., Song, J., Gu, T., Hirschler-Laszkiewicz, I., Koch, W. J., Feldman, A. M., Madesh, M., and Cheung, J. Y. (2014) TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria. J. Biol. Chem. 289, 7615-7629
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 7615-7629
-
-
Miller, B.A.1
Hoffman, N.E.2
Merali, S.3
Zhang, X.Q.4
Wang, J.5
Rajan, S.6
Shanmughapriya, S.7
Gao, E.8
Barrero, C.A.9
Mallilankaraman, K.10
Song, J.11
Gu, T.12
Hirschler-Laszkiewicz, I.13
Koch, W.J.14
Feldman, A.M.15
Madesh, M.16
Cheung, J.Y.17
-
37
-
-
77956197012
-
Mitochondrial complex II prevents hypoxic but not calcium-and proapoptotic Bcl-2 protein-induced mitochondrial membrane potential loss
-
Hawkins, B. J., Levin, M. D., Doonan, P. J., Petrenko, N. B., Davis, C. W., Patel, V. V., and Madesh, M. (2010) Mitochondrial complex II prevents hypoxic but not calcium-and proapoptotic Bcl-2 protein-induced mitochondrial membrane potential loss. J. Biol. Chem. 285, 26494-26505
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 26494-26505
-
-
Hawkins, B.J.1
Levin, M.D.2
Doonan, P.J.3
Petrenko, N.B.4
Davis, C.W.5
Patel, V.V.6
Madesh, M.7
-
38
-
-
80052583012
-
Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alphainduced necrosis
-
Irrinki, K. M., Mallilankaraman, K., Thapa, R. J., Chandramoorthy, H. C., Smith, F. J., Jog, N. R., Gandhirajan, R. K., Kelsen, S. G., Houser, S. R., May, M. J., Balachandran, S., and Madesh, M. (2011) Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alphainduced necrosis. Mol. Cell. Biol. 31, 3745-3758
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 3745-3758
-
-
Irrinki, K.M.1
Mallilankaraman, K.2
Thapa, R.J.3
Chandramoorthy, H.C.4
Smith, F.J.5
Jog, N.R.6
Gandhirajan, R.K.7
Kelsen, S.G.8
Houser, S.R.9
May, M.J.10
Balachandran, S.11
Madesh, M.12
-
39
-
-
34250349160
-
Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling
-
Hawkins, B. J., Madesh, M., Kirkpatrick, C. J., and Fisher, A. B. (2007) Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling. Mol. Biol. Cell 18, 2002-2012
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 2002-2012
-
-
Hawkins, B.J.1
Madesh, M.2
Kirkpatrick, C.J.3
Fisher, A.B.4
-
40
-
-
34548030192
-
2+ homeostasis
-
2+ homeostasis. Immunity 27, 268-280
-
(2007)
Immunity
, vol.27
, pp. 268-280
-
-
Jones, R.G.1
Bui, T.2
White, C.3
Madesh, M.4
Krawczyk, C.M.5
Lindsten, T.6
Hawkins, B.J.7
Kubek, S.8
Frauwirth, K.A.9
Wang, Y.L.10
Conway, S.J.11
Roderick, H.L.12
Bootman, M.D.13
Shen, H.14
Foskett, J.K.15
Thompson, C.B.16
-
41
-
-
27144487808
-
The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R
-
White, C., Li, C., Yang, J., Petrenko, N. B., Madesh, M., Thompson, C. B., and Foskett, J. K. (2005) The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R. Nat. Cell Biol. 7, 1021-1028
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 1021-1028
-
-
White, C.1
Li, C.2
Yang, J.3
Petrenko, N.B.4
Madesh, M.5
Thompson, C.B.6
Foskett, J.K.7
-
42
-
-
0037085380
-
Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization
-
Madesh, M., Antonsson, B., Srinivasula, S. M., Alnemri, E. S., and Hajnoczky, G. (2002) Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization. J. Biol. Chem. 277, 5651-5659
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5651-5659
-
-
Madesh, M.1
Antonsson, B.2
Srinivasula, S.M.3
Alnemri, E.S.4
Hajnoczky, G.5
-
43
-
-
0035842896
-
VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release
-
Madesh, M., and Hajnoczky, G. (2001) VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release. J. Cell Biol. 155, 1003-1015
-
(2001)
J. Cell Biol.
, vol.155
, pp. 1003-1015
-
-
Madesh, M.1
Hajnoczky, G.2
-
44
-
-
79960562130
-
2+ uptake pathways
-
2+ uptake pathways. J. Biol. Chem. 286, 28444-28455
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28444-28455
-
-
Waldeck-Weiermair, M.1
Jean-Quartier, C.2
Rost, R.3
Khan, M.J.4
Vishnu, N.5
Bondarenko, A.I.6
Imamura, H.7
Malli, R.8
Graier, W.F.9
-
45
-
-
84863512330
-
Perspectives on SGP symposium on mitochondrial physiology and medicine: The pathophysiology of LETM1
-
Nowikovsky, K., Pozzan, T., Rizzuto, R., Scorrano, L., and Bernardi, P. (2012) Perspectives on SGP symposium on mitochondrial physiology and medicine: the pathophysiology of LETM1. J. Gen. Physiol. 139, 445-454
-
(2012)
J. Gen. Physiol.
, vol.139
, pp. 445-454
-
-
Nowikovsky, K.1
Pozzan, T.2
Rizzuto, R.3
Scorrano, L.4
Bernardi, P.5
-
46
-
-
77956186783
-
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
-
Hamanaka, R. B., and Chandel, N. S. (2010) Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes. Trends Biochem. Sci. 35, 505-513
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 505-513
-
-
Hamanaka, R.B.1
Chandel, N.S.2
-
47
-
-
77955041880
-
2+ transfer to mitochondria
-
2+ transfer to mitochondria. Cell 142, 270-283
-
(2010)
Cell
, vol.142
, pp. 270-283
-
-
Cardenas, C.1
Miller, R.A.2
Smith, I.3
Bui, T.4
Molgo, J.5
Muller, M.6
Vais, H.7
Cheung, K.H.8
Yang, J.9
Parker, I.10
Thompson, C.B.11
Birnbaum, M.J.12
Hallows, K.R.13
Foskett, J.K.14
-
48
-
-
84891393224
-
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter
-
Pan, X., Liu, J., Nguyen, T., Liu, C., Sun, J., Teng, Y., Fergusson, M. M., Rovira, I. I., Allen, M., Springer, D. A., Aponte, A. M., Gucek, M., Balaban, R. S., Murphy, E., and Finkel, T. (2013) The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter. Nat. Cell Biol. 15, 1464-1472
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 1464-1472
-
-
Pan, X.1
Liu, J.2
Nguyen, T.3
Liu, C.4
Sun, J.5
Teng, Y.6
Fergusson, M.M.7
Rovira, I.I.8
Allen, M.9
Springer, D.A.10
Aponte, A.M.11
Gucek, M.12
Balaban, R.S.13
Murphy, E.14
Finkel, T.15
-
49
-
-
37849038285
-
LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability
-
Dimmer, K. S., Navoni, F., Casarin, A., Trevisson, E., Endele, S., Winterpacht, A., Salviati, L., and Scorrano, L. (2008) LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability. Hum. Mol. Genet. 17, 201-214
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 201-214
-
-
Dimmer, K.S.1
Navoni, F.2
Casarin, A.3
Trevisson, E.4
Endele, S.5
Winterpacht, A.6
Salviati, L.7
Scorrano, L.8
-
50
-
-
84863996302
-
Perspectives on SGP symposium on mitochondrial physiology and medicine: The renaissance of mitochondrial pH
-
Santo-Domingo, J., and Demaurex, N. (2012) Perspectives on SGP symposium on mitochondrial physiology and medicine: the renaissance of mitochondrial pH. J. Gen. Physiol. 139, 415-423
-
(2012)
J. Gen. Physiol.
, vol.139
, pp. 415-423
-
-
Santo-Domingo, J.1
Demaurex, N.2
-
51
-
-
84864007171
-
Perspectives on SGP symposium on mitochondrial physiology and medicine: Mitochondria take center stage
-
Sheu, S. S., Dirksen, R. T., and Pugh, E. N., Jr. (2012) Perspectives on SGP symposium on mitochondrial physiology and medicine: mitochondria take center stage. J. Gen. Physiol. 139, 391-393
-
(2012)
J. Gen. Physiol.
, vol.139
, pp. 391-393
-
-
Sheu, S.S.1
Dirksen, R.T.2
Pugh, E.N.3
-
52
-
-
50249158546
-
Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAAATPase BCS1L
-
Tamai, S., Iida, H., Yokota, S., Sayano, T., Kiguchiya, S., Ishihara, N., Hayashi, J., Mihara, K., and Oka, T. (2008) Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAAATPase BCS1L. J. Cell Sci. 121, 2588-2600
-
(2008)
J. Cell Sci.
, vol.121
, pp. 2588-2600
-
-
Tamai, S.1
Iida, H.2
Yokota, S.3
Sayano, T.4
Kiguchiya, S.5
Ishihara, N.6
Hayashi, J.7
Mihara, K.8
Oka, T.9
-
53
-
-
80053035284
-
AMP-activated protein kinase: An energy sensor that regulates all aspects of cell function
-
Hardie, D. G. (2011) AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. Genes Dev. 25, 1895-1908
-
(2011)
Genes Dev.
, vol.25
, pp. 1895-1908
-
-
Hardie, D.G.1
|