메뉴 건너뛰기




Volumn 232, Issue 1, 2015, Pages 310-325

Exposure to zearalenone mycotoxin alters in vitro porcine intestinal epithelial cells by differential gene expression

Author keywords

Epithelial intestinal cell (IPEC 1); Gene expression; Microarray; Pig; Zearalenone

Indexed keywords

GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE PEROXIDASE 2; GLUTATHIONE PEROXIDASE 6; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZEARALENONE;

EID: 84911939581     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.10.022     Document Type: Article
Times cited : (62)

References (79)
  • 1
    • 0037204953 scopus 로고    scopus 로고
    • A road map for those who don't know JAK-STAT
    • Aaronson D.S., Horvath C.M. A road map for those who don't know JAK-STAT. Science 2002, 296:1653-1655.
    • (2002) Science , vol.296 , pp. 1653-1655
    • Aaronson, D.S.1    Horvath, C.M.2
  • 2
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S., Takeda K. Toll-like receptor signalling. Nat. Rev. Imunol. 2004, 4:499-511.
    • (2004) Nat. Rev. Imunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 4
    • 77649188170 scopus 로고    scopus 로고
    • Innate immune activation of swine intestinal epithelial cell lines (IPEC-J2 and IPI-2I) in response to LPS from Salmonella typhimurium
    • Arce C., Ramirez-Boo M., Lucena C., Garrido J.J. Innate immune activation of swine intestinal epithelial cell lines (IPEC-J2 and IPI-2I) in response to LPS from Salmonella typhimurium. Comp. Immunol. Microbiol. Infect. Dis 2010, 33:161-174.
    • (2010) Comp. Immunol. Microbiol. Infect. Dis , vol.33 , pp. 161-174
    • Arce, C.1    Ramirez-Boo, M.2    Lucena, C.3    Garrido, J.J.4
  • 5
    • 0029032159 scopus 로고
    • Induction of cytokine mRNAs in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): relationship to toxin distribution and protein synthesis inhibition
    • Azcona-Olivera J., Ouang J., Murtha J., Chu F., Pestka J. Induction of cytokine mRNAs in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): relationship to toxin distribution and protein synthesis inhibition. Toxicol. Appl. Pharmacol. 1995, 133:109-120.
    • (1995) Toxicol. Appl. Pharmacol. , vol.133 , pp. 109-120
    • Azcona-Olivera, J.1    Ouang, J.2    Murtha, J.3    Chu, F.4    Pestka, J.5
  • 8
    • 24944587966 scopus 로고    scopus 로고
    • The effects of mycotoxins fungal food contaminants, on the intestinal epithelial cell-derived innate immune response
    • Bouhet S., Oswald I.P. The effects of mycotoxins fungal food contaminants, on the intestinal epithelial cell-derived innate immune response. Vet. Immunol. Immunopathol. 2005, 108:199-209.
    • (2005) Vet. Immunol. Immunopathol. , vol.108 , pp. 199-209
    • Bouhet, S.1    Oswald, I.P.2
  • 10
    • 33747071420 scopus 로고    scopus 로고
    • Mycotoxin fumonisin B1 selectively down-regulates the basal IL-8 expression in pig intestine: in vivo and in vitro studies
    • Bouhet S., Le Dorze E., Peres S., Fairbrother J.M., Oswald I.P. Mycotoxin fumonisin B1 selectively down-regulates the basal IL-8 expression in pig intestine: in vivo and in vitro studies. Food Chem. Toxicol. 2006, 44:1768-1773.
    • (2006) Food Chem. Toxicol. , vol.44 , pp. 1768-1773
    • Bouhet, S.1    Le Dorze, E.2    Peres, S.3    Fairbrother, J.M.4    Oswald, I.P.5
  • 11
    • 8644255915 scopus 로고    scopus 로고
    • Homing endonuclease genes: the rise and fall and rise again of a selfish element
    • Burt A., Koufopanou V. Homing endonuclease genes: the rise and fall and rise again of a selfish element. Curr. Opin. Genet. Dev. 2004, 14:609-615.
    • (2004) Curr. Opin. Genet. Dev. , vol.14 , pp. 609-615
    • Burt, A.1    Koufopanou, V.2
  • 12
    • 27144511502 scopus 로고    scopus 로고
    • Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity
    • Cho J.H., Fraser I.P., Fukase K., Kusumoto S., Fujimoto Y., Stahl G.L., Ezekowitz R.A. Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity. Blood 2005, 106:2551-2558.
    • (2005) Blood , vol.106 , pp. 2551-2558
    • Cho, J.H.1    Fraser, I.P.2    Fukase, K.3    Kusumoto, S.4    Fujimoto, Y.5    Stahl, G.L.6    Ezekowitz, R.A.7
  • 14
    • 0037447609 scopus 로고    scopus 로고
    • Up-regulation of macrophage inflammatory protein-2 and complement 3A receptor by the trichothecenes deoxynivalenol and satratoxin G
    • Chung Y.-J., Yang G.-H., Islam Z., Pestka J. Up-regulation of macrophage inflammatory protein-2 and complement 3A receptor by the trichothecenes deoxynivalenol and satratoxin G. Toxicology 2003, 186:51-65.
    • (2003) Toxicology , vol.186 , pp. 51-65
    • Chung, Y.-J.1    Yang, G.-H.2    Islam, Z.3    Pestka, J.4
  • 16
    • 67650700710 scopus 로고    scopus 로고
    • The food contaminant fumonisin B1 reduces the maturation of porcine CD11R1+ intestinal antigen presenting cells and antigen-specific immune responses, leading to a prolonged intestinal ETEC infection
    • Devriendt B., Gallois M., Verdonck F., Wache Y., Bimczok D., Oswald I.P., Goddeeris B.M., Cox E. The food contaminant fumonisin B1 reduces the maturation of porcine CD11R1+ intestinal antigen presenting cells and antigen-specific immune responses, leading to a prolonged intestinal ETEC infection. Vet. Res. 2009, 40:40.
    • (2009) Vet. Res. , vol.40 , pp. 40
    • Devriendt, B.1    Gallois, M.2    Verdonck, F.3    Wache, Y.4    Bimczok, D.5    Oswald, I.P.6    Goddeeris, B.M.7    Cox, E.8
  • 18
    • 1642504808 scopus 로고    scopus 로고
    • Characteristic expression profiles induced by genotoxic carcinogens in rat liver
    • Ellinger-Ziegelbauer H., Stuart B., Wahle B., Bomann W., Ahr H. Characteristic expression profiles induced by genotoxic carcinogens in rat liver. Toxicol. Sci. 2004, 7:19-34.
    • (2004) Toxicol. Sci. , vol.7 , pp. 19-34
    • Ellinger-Ziegelbauer, H.1    Stuart, B.2    Wahle, B.3    Bomann, W.4    Ahr, H.5
  • 21
    • 0035692705 scopus 로고    scopus 로고
    • Cellular and subcellular localization of gastrointestinal glutathione peroxidase in normal and malignant human intestinal tissue
    • Florian S., Wingler K., Schmehl K., Jacobasch G., Kreuzer O.J., Meyerhof W., Brigelius-Flohé R. Cellular and subcellular localization of gastrointestinal glutathione peroxidase in normal and malignant human intestinal tissue. Free Rad. Res. 2001, 35:655-663.
    • (2001) Free Rad. Res. , vol.35 , pp. 655-663
    • Florian, S.1    Wingler, K.2    Schmehl, K.3    Jacobasch, G.4    Kreuzer, O.J.5    Meyerhof, W.6    Brigelius-Flohé, R.7
  • 24
    • 84870996397 scopus 로고    scopus 로고
    • Porcine intestinal epithelial barrier disruption by the Fusariummycotoxinsdeoxynivalenol and T-2 toxin promotes transepithelial passage of doxycycline and paromomycin
    • Goossens J., Pasmans F., Verbrugghe E., Vandenbroucke V., De Baere S., Meyer E., Haesebrouck F., De Backer P., Croubels S. Porcine intestinal epithelial barrier disruption by the Fusariummycotoxinsdeoxynivalenol and T-2 toxin promotes transepithelial passage of doxycycline and paromomycin. BMC Vet. Res. 2012, 8:245.
    • (2012) BMC Vet. Res. , vol.8 , pp. 245
    • Goossens, J.1    Pasmans, F.2    Verbrugghe, E.3    Vandenbroucke, V.4    De Baere, S.5    Meyer, E.6    Haesebrouck, F.7    De Backer, P.8    Croubels, S.9
  • 25
    • 34250817463 scopus 로고    scopus 로고
    • Lactobacillus rhamnosus strain GG reduces aflatoxin B1 transport metabolism, and toxicity in Caco-2 cells
    • Gratz S., Wu Q.K., El-Nezami H., Juvonen R.O., Mykkänen H., Turner P.C. Lactobacillus rhamnosus strain GG reduces aflatoxin B1 transport metabolism, and toxicity in Caco-2 cells. Appl. Environ. Microbiol. 2007, 73:3958-3964.
    • (2007) Appl. Environ. Microbiol. , vol.73 , pp. 3958-3964
    • Gratz, S.1    Wu, Q.K.2    El-Nezami, H.3    Juvonen, R.O.4    Mykkänen, H.5    Turner, P.C.6
  • 27
    • 84876047766 scopus 로고    scopus 로고
    • Transcript and protein profiling analysis of the destruxin A-induced response in larvae of Plutella xylostella
    • Han P., Jin F., Dong X., Fan J., Qui B., Ren S. Transcript and protein profiling analysis of the destruxin A-induced response in larvae of Plutella xylostella. PloS One 2013, 8:e60771.
    • (2013) PloS One , vol.8
    • Han, P.1    Jin, F.2    Dong, X.3    Fan, J.4    Qui, B.5    Ren, S.6
  • 28
    • 84888435382 scopus 로고    scopus 로고
    • Rainbow trout peptidoglycan recognition protein has an anti-inflammatory function in liver cells
    • Jang J.H., Kim H., Cho J.H. Rainbow trout peptidoglycan recognition protein has an anti-inflammatory function in liver cells. Fish Shellfish Immunol. 2013, 35:1838-1847.
    • (2013) Fish Shellfish Immunol. , vol.35 , pp. 1838-1847
    • Jang, J.H.1    Kim, H.2    Cho, J.H.3
  • 32
    • 0036773277 scopus 로고    scopus 로고
    • The ribotoxic stress response as a potential mechanism for MAP kinase activation in xenobiotic toxicity
    • Laskin J.D., Heck D.E., Laskin D.L. The ribotoxic stress response as a potential mechanism for MAP kinase activation in xenobiotic toxicity. Toxicol. Sci. 2002, 69:289-291.
    • (2002) Toxicol. Sci. , vol.69 , pp. 289-291
    • Laskin, J.D.1    Heck, D.E.2    Laskin, D.L.3
  • 33
    • 0034077161 scopus 로고    scopus 로고
    • Cellular localization of complement C3 and C4 transcripts in intestinal specimens from patients with Crohn's disease
    • Laufer J., Oren R., Goldberg I., Horwitz A., Kopolovic J., Chowers Y., Passwell J.H. Cellular localization of complement C3 and C4 transcripts in intestinal specimens from patients with Crohn's disease. Clin. Exp. Immunol. 2000, 120:30-37.
    • (2000) Clin. Exp. Immunol. , vol.120 , pp. 30-37
    • Laufer, J.1    Oren, R.2    Goldberg, I.3    Horwitz, A.4    Kopolovic, J.5    Chowers, Y.6    Passwell, J.H.7
  • 34
    • 84872395266 scopus 로고    scopus 로고
    • Growth factor TGF-β induces intestinal epithelial cell (IEC-6) differentiation: miR-146b as a regulatory component in the negative feedback loop
    • Liao Y., Zhang M., Lönnerdal B. Growth factor TGF-β induces intestinal epithelial cell (IEC-6) differentiation: miR-146b as a regulatory component in the negative feedback loop. Genes Nutr. 2013, 8:69-78.
    • (2013) Genes Nutr. , vol.8 , pp. 69-78
    • Liao, Y.1    Zhang, M.2    Lönnerdal, B.3
  • 35
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and 482 the 2(-delta delta C(T)) method
    • Litvak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and 482 the 2(-delta delta C(T)) method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Litvak, K.J.1    Schmittgen, T.D.2
  • 37
    • 47849117947 scopus 로고    scopus 로고
    • Effects of four Fusarium toxins (fumonisin B (1), alpha-zearalenol, nivalenol and deoxynivalenol) on porcine whole-blood cellular proliferation
    • Luongo D., De Luna R., Russo R., Severino L. Effects of four Fusarium toxins (fumonisin B (1), alpha-zearalenol, nivalenol and deoxynivalenol) on porcine whole-blood cellular proliferation. Toxicon 2008, 52:156-162.
    • (2008) Toxicon , vol.52 , pp. 156-162
    • Luongo, D.1    De Luna, R.2    Russo, R.3    Severino, L.4
  • 38
    • 77954144537 scopus 로고    scopus 로고
    • Some food-associated mycotoxins as potential risk factors in humans predisposed to chronic intestinal inflammatory diseases
    • Maresca M., Fantini J. Some food-associated mycotoxins as potential risk factors in humans predisposed to chronic intestinal inflammatory diseases. Toxicon 2010, 56:282-294.
    • (2010) Toxicon , vol.56 , pp. 282-294
    • Maresca, M.1    Fantini, J.2
  • 39
    • 0036714478 scopus 로고    scopus 로고
    • The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells
    • Maresca M., Mahfoud R., Garmy N., Fantini J. The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. J. Nutr. 2002, 132:2723-2731.
    • (2002) J. Nutr. , vol.132 , pp. 2723-2731
    • Maresca, M.1    Mahfoud, R.2    Garmy, N.3    Fantini, J.4
  • 40
    • 40849101434 scopus 로고    scopus 로고
    • Both direct and indirect effects account for the proinflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: stimulation of interleukin-8 secretion, potentiation of interleukin-1beta effect and increase in the transepithelial passage of commensal bacteria
    • Maresca M., Yahi N., Younès-Sakr L., Boyron M., Caporiccio B., Fantini J. Both direct and indirect effects account for the proinflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: stimulation of interleukin-8 secretion, potentiation of interleukin-1beta effect and increase in the transepithelial passage of commensal bacteria. Toxicol. Appl. Pharmacol. 2008, 228:84-92.
    • (2008) Toxicol. Appl. Pharmacol. , vol.228 , pp. 84-92
    • Maresca, M.1    Yahi, N.2    Younès-Sakr, L.3    Boyron, M.4    Caporiccio, B.5    Fantini, J.6
  • 41
    • 77956062484 scopus 로고    scopus 로고
    • Effects of zearalenone and its derivatives on the innate immune response in swine
    • Marin D.E., Taranu I., Burlacu R., Tudor D.S. Effects of zearalenone and its derivatives on the innate immune response in swine. Toxicon 2010, 56:956-963.
    • (2010) Toxicon , vol.56 , pp. 956-963
    • Marin, D.E.1    Taranu, I.2    Burlacu, R.3    Tudor, D.S.4
  • 43
    • 84879316669 scopus 로고    scopus 로고
    • Effects of zearalenone on oxidative stress and inflammation in weanling piglets
    • Marin D.E., Pistol G.C., Neagoe I.V., Calin L., Taranu I. Effects of zearalenone on oxidative stress and inflammation in weanling piglets. Food Chem. Toxicol. 2013, 58:408-415.
    • (2013) Food Chem. Toxicol. , vol.58 , pp. 408-415
    • Marin, D.E.1    Pistol, G.C.2    Neagoe, I.V.3    Calin, L.4    Taranu, I.5
  • 45
    • 0036232403 scopus 로고    scopus 로고
    • Prolonged dietary treatment with conjugated linoleic acid stimulates porcine muscle peroxisome proliferator activated receptor γ and glutamine-fructose aminotransferase gene expression in vivo
    • Meadus W.J., MacInnis R., Dugan M.E.R. Prolonged dietary treatment with conjugated linoleic acid stimulates porcine muscle peroxisome proliferator activated receptor γ and glutamine-fructose aminotransferase gene expression in vivo. J. Mol. Endocrinol. 2002, 28:79-86.
    • (2002) J. Mol. Endocrinol. , vol.28 , pp. 79-86
    • Meadus, W.J.1    MacInnis, R.2    Dugan, M.E.R.3
  • 46
    • 58249111561 scopus 로고    scopus 로고
    • Early immune response following Salmonella enterica subspecies enterica serovar typhimurium infection in porcine jejunal gut loops
    • Meurens F., Berri M., Auray G., Melo S., Levast B., Virlogeux-Payant I., Chevaleyre C., Gerdts V., Salmon H. Early immune response following Salmonella enterica subspecies enterica serovar typhimurium infection in porcine jejunal gut loops. Vet. Res. 2009, 40:05.
    • (2009) Vet. Res. , vol.40 , pp. 05
    • Meurens, F.1    Berri, M.2    Auray, G.3    Melo, S.4    Levast, B.5    Virlogeux-Payant, I.6    Chevaleyre, C.7    Gerdts, V.8    Salmon, H.9
  • 47
    • 59449085506 scopus 로고    scopus 로고
    • Broad early immune response of porcine epithelial jejunal IPI-2I cells to Entamoeba histolytica
    • Meurens F., Girard-Misguich F., Melo S., Grave A., Salmon H., Guillén N. Broad early immune response of porcine epithelial jejunal IPI-2I cells to Entamoeba histolytica. Mol. Immunol. 2009, 46:927-936.
    • (2009) Mol. Immunol. , vol.46 , pp. 927-936
    • Meurens, F.1    Girard-Misguich, F.2    Melo, S.3    Grave, A.4    Salmon, H.5    Guillén, N.6
  • 48
    • 48449099149 scopus 로고    scopus 로고
    • Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol
    • Moon Y., Yang H., Park S.H. Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol. Toxicol. Appl. Pharmacol. 2008, 231:94-102.
    • (2008) Toxicol. Appl. Pharmacol. , vol.231 , pp. 94-102
    • Moon, Y.1    Yang, H.2    Park, S.H.3
  • 49
    • 0036449063 scopus 로고    scopus 로고
    • Signal transduction pathways activated by the IL-1 receptor/toll-like receptor superfamily
    • O'Neill L.A. Signal transduction pathways activated by the IL-1 receptor/toll-like receptor superfamily. Curr. Top Microbiol. Immunol. 2002, 270:47-61.
    • (2002) Curr. Top Microbiol. Immunol. , vol.270 , pp. 47-61
    • O'Neill, L.A.1
  • 50
    • 70449435758 scopus 로고    scopus 로고
    • Temporal regulation of BMP2, BMP6, BMP15, GDF9, BMPR1A, BMPR1B, BMPR2 and TGFBR1 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig
    • Paradis F., Novak S., Murdoch G.K., Dyck M.K., Dixon W.T., Foxcroft G.R. Temporal regulation of BMP2, BMP6, BMP15, GDF9, BMPR1A, BMPR1B, BMPR2 and TGFBR1 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig. Reproduction 2009, 138:115-129.
    • (2009) Reproduction , vol.138 , pp. 115-129
    • Paradis, F.1    Novak, S.2    Murdoch, G.K.3    Dyck, M.K.4    Dixon, W.T.5    Foxcroft, G.R.6
  • 51
    • 67650163433 scopus 로고    scopus 로고
    • Expression profiling of the genes responding to zearalenone and its analogues using estrogen-responsive genes
    • Parveen M., Zhu Y., Kiyama R. Expression profiling of the genes responding to zearalenone and its analogues using estrogen-responsive genes. FEBS Lett. 2009, 583:2377-2384.
    • (2009) FEBS Lett. , vol.583 , pp. 2377-2384
    • Parveen, M.1    Zhu, Y.2    Kiyama, R.3
  • 52
    • 2942548177 scopus 로고    scopus 로고
    • Tumor suppressor gene E-cadherin and its role in normal and malignant cells
    • Pecina-Slaus N. Tumor suppressor gene E-cadherin and its role in normal and malignant cells. Cancer cell. Int. 2003, 3:17.
    • (2003) Cancer cell. Int. , vol.3 , pp. 17
    • Pecina-Slaus, N.1
  • 53
  • 54
    • 70849100264 scopus 로고    scopus 로고
    • Mechanisms of deoxynivalenol-induced gene expression and apoptosis
    • Pestka J.J. Mechanisms of deoxynivalenol-induced gene expression and apoptosis. Food Addit. Contam. A 2008, 25:1128-1140.
    • (2008) Food Addit. Contam. A , vol.25 , pp. 1128-1140
    • Pestka, J.J.1
  • 56
    • 78149245857 scopus 로고    scopus 로고
    • Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase-dependent mechanism
    • Pinton P., Braicu C., Nougayrède J.-P., Laffitte J., Taranu I., Oswald I.P. Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase-dependent mechanism. J. Nutr. 2010, 140:1956-1962.
    • (2010) J. Nutr. , vol.140 , pp. 1956-1962
    • Pinton, P.1    Braicu, C.2    Nougayrède, J.-P.3    Laffitte, J.4    Taranu, I.5    Oswald, I.P.6
  • 57
    • 84893661958 scopus 로고    scopus 로고
    • The natural feed contaminant zearalenone decreases expression of important pro- and anti-inflammatory related mediators and MAPKs/NFkB signaling molecules in pig
    • Pistol G.C., Gras M.A., Marin D.E., Israel Roming F., Stancu M., Taranu I. The natural feed contaminant zearalenone decreases expression of important pro- and anti-inflammatory related mediators and MAPKs/NFkB signaling molecules in pig. Br. J. Nutr. 2014, 111:452-464.
    • (2014) Br. J. Nutr. , vol.111 , pp. 452-464
    • Pistol, G.C.1    Gras, M.A.2    Marin, D.E.3    Israel Roming, F.4    Stancu, M.5    Taranu, I.6
  • 60
    • 35948944283 scopus 로고    scopus 로고
    • Some major mycotoxins and their mycotoxicoses-an overview
    • Richard J.L. Some major mycotoxins and their mycotoxicoses-an overview. Int. J. Food Microbiol. 2007, 119:3-10.
    • (2007) Int. J. Food Microbiol. , vol.119 , pp. 3-10
    • Richard, J.L.1
  • 62
    • 0035006284 scopus 로고    scopus 로고
    • Structure and biology of complement protein C3, a connecting link between innate and acquired immunity
    • Sahu A., Lambris J.D. Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunol. Rev. 2001, 180:35-48.
    • (2001) Immunol. Rev. , vol.180 , pp. 35-48
    • Sahu, A.1    Lambris, J.D.2
  • 63
    • 33745044469 scopus 로고    scopus 로고
    • Deoxynivalenol transport across human intestinal caco-2 cells and its effects on cellular metabolism at realistic intestinal concentrations
    • Sergent T., Parys M., Garsou S., Pussemier L., Schneider Y.J., Larondelle Y. Deoxynivalenol transport across human intestinal caco-2 cells and its effects on cellular metabolism at realistic intestinal concentrations. Toxicol. Lett. 2006, 164:167-176.
    • (2006) Toxicol. Lett. , vol.164 , pp. 167-176
    • Sergent, T.1    Parys, M.2    Garsou, S.3    Pussemier, L.4    Schneider, Y.J.5    Larondelle, Y.6
  • 64
    • 81255158786 scopus 로고    scopus 로고
    • IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens
    • Song X., Zhu S., Shi P., Liu Y., Shy Y., Levin S.D., Qian Y. IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat. Immunol. 2011, 12:1151-1158.
    • (2011) Nat. Immunol. , vol.12 , pp. 1151-1158
    • Song, X.1    Zhu, S.2    Shi, P.3    Liu, Y.4    Shy, Y.5    Levin, S.D.6    Qian, Y.7
  • 65
    • 62349088958 scopus 로고    scopus 로고
    • Molds and mycotoxin content of cereals in southeastern Romania
    • Tabuc C., Marin D., Guerre P., Sesan T., Bailly J.D. Molds and mycotoxin content of cereals in southeastern Romania. J. Food Prot. 2009, 72:662-665.
    • (2009) J. Food Prot. , vol.72 , pp. 662-665
    • Tabuc, C.1    Marin, D.2    Guerre, P.3    Sesan, T.4    Bailly, J.D.5
  • 66
    • 84888306067 scopus 로고    scopus 로고
    • Interactive effects of zearalenone and its metabolites on cytotoxicity and metabolization in ovarian CHO-K1 cells
    • Tatay E., Meca G., Font G., Ruiz M.J. Interactive effects of zearalenone and its metabolites on cytotoxicity and metabolization in ovarian CHO-K1 cells. Toxicol. In Vitro 2014, 28:95-103.
    • (2014) Toxicol. In Vitro , vol.28 , pp. 95-103
    • Tatay, E.1    Meca, G.2    Font, G.3    Ruiz, M.J.4
  • 68
    • 33847110271 scopus 로고    scopus 로고
    • In vivo and in vitro effects of the mycotoxins zearalenone and deoxynivalenol on different non-reproductive and reproductive organs in female pigs: a review
    • Tiemann U., Dänicke S. In vivo and in vitro effects of the mycotoxins zearalenone and deoxynivalenol on different non-reproductive and reproductive organs in female pigs: a review. Food Addit. Contam. 2007, 24:306-314.
    • (2007) Food Addit. Contam. , vol.24 , pp. 306-314
    • Tiemann, U.1    Dänicke, S.2
  • 69
    • 65449154388 scopus 로고    scopus 로고
    • Feeding of pregnant sows with mycotoxin-contaminated diets and their non-effect on foetal and maternal hepatic transcription of genes of the insulin-like growth factor system
    • Tiemann U., Brüssow K.P., Danicke S., Vanselow J. Feeding of pregnant sows with mycotoxin-contaminated diets and their non-effect on foetal and maternal hepatic transcription of genes of the insulin-like growth factor system. Food Addit. Contam. A 2008, 25:1365-1373.
    • (2008) Food Addit. Contam. A , vol.25 , pp. 1365-1373
    • Tiemann, U.1    Brüssow, K.P.2    Danicke, S.3    Vanselow, J.4
  • 70
    • 45849116247 scopus 로고    scopus 로고
    • The effect of feeding a diet naturally contaminated with deoxynivalenol (DON) and zearalenone (ZON) on the spleen and liver of sow and fetus from day 35 to 70 of gestation
    • Tiemann U., Brüssow K.P., Dannenberger D., Jonas L., Pöhland R., Jäger K., Dänicke S., Hagemann E. The effect of feeding a diet naturally contaminated with deoxynivalenol (DON) and zearalenone (ZON) on the spleen and liver of sow and fetus from day 35 to 70 of gestation. Toxicol. Lett. 2008, 179:113-117.
    • (2008) Toxicol. Lett. , vol.179 , pp. 113-117
    • Tiemann, U.1    Brüssow, K.P.2    Dannenberger, D.3    Jonas, L.4    Pöhland, R.5    Jäger, K.6    Dänicke, S.7    Hagemann, E.8
  • 71
    • 0025818032 scopus 로고
    • Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion supressor role
    • Vleminckx K., Vakaet L., Mareel M., Fiers W., van Roy F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion supressor role. Cell 1991, 66:107-119.
    • (1991) Cell , vol.66 , pp. 107-119
    • Vleminckx, K.1    Vakaet, L.2    Mareel, M.3    Fiers, W.4    van Roy, F.5
  • 73
    • 84877112029 scopus 로고    scopus 로고
    • Individual and combined cytotoxic effects of Fusarium toxins (deoxynivalenol nivalenol, zearalenone and fumonisins B1) on swine jejunal epithelial cells
    • Wan L.Y., Turner P.C., El-Nezami H. Individual and combined cytotoxic effects of Fusarium toxins (deoxynivalenol nivalenol, zearalenone and fumonisins B1) on swine jejunal epithelial cells. Food Chem.Toxicol. 2013, 57:276-283.
    • (2013) Food Chem.Toxicol. , vol.57 , pp. 276-283
    • Wan, L.Y.1    Turner, P.C.2    El-Nezami, H.3
  • 74
    • 82655171586 scopus 로고    scopus 로고
    • LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells
    • Ward Y., Lake R., Yin J.J., Heger D., Raffeld M., Goldsmith P.K., Merino M., Kelly K. LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells. Cancer Res. 2011, 71:7301-7311.
    • (2011) Cancer Res. , vol.71 , pp. 7301-7311
    • Ward, Y.1    Lake, R.2    Yin, J.J.3    Heger, D.4    Raffeld, M.5    Goldsmith, P.K.6    Merino, M.7    Kelly, K.8
  • 75
    • 70450189840 scopus 로고    scopus 로고
    • TGF beta family signaling: novel insights in development and disease
    • Wharton K., Derynck R. TGF beta family signaling: novel insights in development and disease. Development 2009, 136:3691-3697.
    • (2009) Development , vol.136 , pp. 3691-3697
    • Wharton, K.1    Derynck, R.2
  • 77
    • 63249087088 scopus 로고    scopus 로고
    • Toxicological and gene expression analysis of the impact of aflatoxin B1 on hepatic function of male broiler chicks
    • Yarru L.P., Settivari R.S., Antoniou E., Ledoux D.R., Rottinghaus G.E. Toxicological and gene expression analysis of the impact of aflatoxin B1 on hepatic function of male broiler chicks. Poult. Sci. 2009, 88:360-371.
    • (2009) Poult. Sci. , vol.88 , pp. 360-371
    • Yarru, L.P.1    Settivari, R.S.2    Antoniou, E.3    Ledoux, D.R.4    Rottinghaus, G.E.5
  • 78
    • 0035099082 scopus 로고    scopus 로고
    • Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1)
    • Zhang Y., Jones C., Dickman M.B. Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). Food Chem. Toxicol. 2001, 39:45-53.
    • (2001) Food Chem. Toxicol. , vol.39 , pp. 45-53
    • Zhang, Y.1    Jones, C.2    Dickman, M.B.3
  • 79
    • 84880820010 scopus 로고    scopus 로고
    • Gene silencing of porcine MUC13 and ITGB5: candidate genes towards Escherichia coli F4ac adhesion
    • Zhou C., Liu Z., Liu Y., Fu W., Ding X., Liu J., Yu Y., Zhang Q. Gene silencing of porcine MUC13 and ITGB5: candidate genes towards Escherichia coli F4ac adhesion. PloS One 2013, 8:e70303.
    • (2013) PloS One , vol.8 , pp. e70303
    • Zhou, C.1    Liu, Z.2    Liu, Y.3    Fu, W.4    Ding, X.5    Liu, J.6    Yu, Y.7    Zhang, Q.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.