Feeding of pregnant sows with mycotoxin-contaminated diets and their non-effect on foetal and maternal hepatic transcription of genes of the insulin-like growth factor system

Food Additives and Contaminants - Part A

Volumn 25, Issue 11, 2008, Pages 1365-1373

  Tiemann, U ^a   Brussow K P ^a   Danicke S ^b   Vanselow, J ^c  

^a Research Unit Reproductive Biology   (Germany)

^b INSTITUTE FOR EPIDEMIOLOGY AND PATHOGEN DIAGNOSTICS   (Germany)

^c LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

Author keywords

Deoxynivalenol; Foetus; Insulin like growth factor (IGF) system; Liver; Neonatal pig; Zearalenone

Indexed keywords

SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; VOMITOXIN; ZEARALENONE;

ARTICLE; CONTROLLED STUDY; FEMALE; FETOTOXICITY; FETUS; FOOD ANALYSIS; FOOD CONTAMINATION; FOOD INTAKE; FUSARIUM; GENE EXPRESSION; GENETIC TRANSCRIPTION; GROWTH RETARDATION; LIVER FUNCTION; NONHUMAN; ONTOGENY; POLYMERASE CHAIN REACTION; PRENATAL EXPOSURE; PRIORITY JOURNAL; SOW (SWINE); WEIGHT REDUCTION;

SUIDAE;

EID: 65449154388     PISSN: 19440049     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/02652030802112619     Document Type: Article

References (54)

1. Adams, SO, Nissley, SP, Handwerger, S. and Rechler, MM (1983) Developmental patterns of insulin-like growth factor-I and -II synthesis and regulation in rat fibroblasts. Nature, 302, pp. 150-153.
2. Alm, H., Brussow, KP, Torner, H., Vanselow, J., Tomek, W., Danicke, S. and Tiemann, U. (2006) Influence of Fusarium-toxin contaminated feed on initial quality and meiotic competence of gilt oocytes. Reprod Toxicol, 22, pp. 44-50.
3. Ashworth, CJ, Finch, AM, Page, KR, Nwagwu, MO and McArdle, HJ (2001) Causes and consequences of foetal growth retardation in pigs. Reprod. Suppl, 58, pp. 233-246.
4. Butler, AA and LeRoith, D. (2001) Control of growth by the somatropic axis: Growth hormone and the insulin-like growth factors have related and independent roles. Annu Rev Physiol, 63, pp. 141-164.
5. Chin, E., Zhou, J., Dai, J., Baxter, RC and Bondy, CA (1994) Cellular localization and regulation of gene expression for components of the insulin-like growth factor ternary binding protein complex. Endocrinology, 134, pp. 2498-2504.
6. Commission of the European Communities (2006) Commission recommendation of 17 August 2006: On the presence of deoxynovalenol, zearalenone, orchratoxin A, T-2 and HT-2 and fumonisins in products intended for animal feeding. Off J Eur Union, pp. 7-9.
7. Conkova, E., Laciakova, A., Kovac, G. and Seidel, H. (2003) Fusarial toxins and their role in animal diseases. Vet J, 165, pp. 214-220.
8. Coulter, CL, Goldsmith, PC, Mesiano, S., Voytek, CC, Martin, MC, Han, VK and Jaffe, RB (1996) Functional maturation of the primate foetal adrenal in vivo: I. Role of insulin-like growth factors (IGFs), IGF-I receptor, and IGF binding proteins in growth regulation. Endocrinology, 137, pp. 4487-4498.
9. D'Ercole, AJ (1996) Insulin-like growth factors and their receptors in growth. Endocrin Metab Clin North America, 25, pp. 573-590.
10. Dänicke, S. (2002) Fusariumtoxine in der Tierernahrung. Grosstierpraxis, 3, pp. 5-18.
11. Dänicke, S., Brüssow, KP, Goyarts, T., Valenta, H., Ueberschär, KH and Tiemann, U. (2007) On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from the sow to the full-term piglet during the last third of gestation. Food Chem Toxicol, 45, pp. 1565-1574.
12. Dänicke, S., Brüssow, KP, Valenta, H., Ueberschär, KH, Tiemann, U. and Schollenberger, M. (2005) On the effects of graded levels of Fusarium toxin contaminated wheat in diets for gilts on feed intake, growth performance and metabolism of deoxynivalenol and zearalenone. Mol Nutr Food Res, 49, pp. 932-943.
13. Daughaday, WH and Rotwein, P. (1989) Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev, 10, pp. 68-91.
14. DeChiara, TM, Efstratiadis, A. and Robertson, EJ (1990) A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature, 345, pp. 78-80.
15. Delhanty, PJ and Han, VK (1993) The expression of insulin-like growth factor (IGF)-binding protein-2 and IGF-II genes in the tissues of the developing ovine fetus. Endocrinology, 132, pp. 41-52.
16. DeVrijer, B., Davidsen, ML, Wilkening, RB, Anthony, RV and Regnault, TR (2006) Altered placental and foetal expression of IGFs and IGF-binding proteins associated with intrauterine growth restriction in foetal sheep during early and mid-pregnancy. Pediatr Res, 60, pp. 507-512.
17. Diekman, MA and Green, ML (1992) Mycotoxins and reproduction in domestic livestock. J Anim Sci, 70, pp. 1615-1627.
18. Donovan, SM, Giudice, LC, Murphy, LJ, Hintz, RL and Rosenfeld, RG (1991) Maternal insulin-like growth factor-binding protein messenger ribonucleic acid during rat pregnancy. Endocrinology, 129, pp. 3359-3366.
19. Dunaiski, V., Dunshea, FR, Walton, PE and Goddard, C. (1999) Effect of growth hormone administration on IGF binding protein-3 mRNA levels in porcine tissues. J Mol Endocrinol, 22, pp. 261-272.
20. Fink-Gremmels, J. (1999) Mycotoxins: Their implications for human and animal health. Vet Q, 21, pp. 115-120.
21. Forhead, AJ, Li, J., Gilmour, RS and Fowden, AL (1998) Control of hepatic insulin-like growth factor II gene expression by thyroid hormones in foetal sheep near term. Am J Physiol, 275, pp. E149-E156.
22. Giudice, LC, Milkowski, DA, Lamson, G., Rosenfeld, RG and Irwin, JC (1991) Insulin-like growth factor binding proteins in human endometrium: steroid-dependent messenger ribonucleic acid expression and protein synthesis. J Clin Endocrinol Metab, 72, pp. 779-787.
23. Gluckman, PD (1995) Insulin-like growth factors and their binding proteins. Fetus and neonate. Physiology and clinical applications, p. 97. Cambridge University Press., Cambridge
24. Gluckman, PD and Butler, JH (1983) Parturition-related changes in insulin-like growth factors-I and -II in the perinatal lamb. J Endocrinol, 99, pp. 223-232.
25. Gluckman, PD, Johnson-Barrett, JJ, Butler, JH, Edgar, BW and Gunn, TR (1983) Studies of insulin-like growth factor -I and -II by specific radioligand assays in umbilical cord blood. Clin Endocrinol (Oxf.), 19, pp. 405-413.
26. Goyarts, T., Danicke, S., Brussow, KP, Valenta, H., Ueberschar, KH and Tiemann, U. (2007) On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from sows to their fetuses during days 35-70 of gestation. Toxicol Lett, 171, pp. 38-49.
27. Han, VKM and Hill, DJ (1992) The involvement of insulin-like growth factors in embryonic and foetal development. The insulin-like growth factors. Structure and biological functions, p. 178. Oxford University Press., Oxford
28. Hussein, HS and Brasel, JM (2001) Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology, 167, pp. 101-134.
29. Jones, JI and Clemmons, DR (1995) Insulin-like growth factors and their binding proteins: Biological actions. Endocr Rev, 16, pp. 3-34.
30. Kampman, KA, Ramsay, TG and White, ME (1993) Developmental changes in hepatic IGF-2 and IGFBP-2 mRNA levels in intrauterine growth-retarded and control swine. Comp Biochem Physiol B, 104, pp. 415-421.
31. Ketelslegers, JM, Maiter, D., Maes, M., Underwood, LE and Thissen, JP (1995) Nutritional regulation of insulin-like growth factor-I. Metabolism, 44, pp. 50-57.
32. Lassarre, C. and Binoux, M. (1994) Insulin-like growth factor binding protein-3 is functionally altered in pregnancy plasma. Endocrinology, 134, pp. 1254-1262.
33. Lee, CY, Bazer, FW, Etherton, TD and Simmen, FA (1991) Ontogeny of insulin-like growth factors (IGF-I and IGF-II) and IGF-binding proteins in porcine serum during foetal and postnatal development. Endocrinology, 128, pp. 2336-2344.
34. Lee, CY, Chung, CS and Simmen, FA (1993) Ontogeny of the porcine insulin-like growth factor system. Mol Cell Endocrinol, 93, pp. 71-80.
35. Li, J., Owens, JA, Owens, PC, Saunders, JC, Fowden, AL and Gilmour, RS (1996) The ontogeny of hepatic growth hormone receptor and insulin-like growth factor I gene expression in the sheep fetus during late gestation: Developmental regulation by cortisol. Endocrinology, 137, pp. 1650-1657.
36. Li, J., Saunders, JC, Gilmour, RS, Silver, M. and Fowden, AL (1993) Insulin-like growth factor-II messenger ribonucleic acid expression in foetal tissues of the sheep during late gestation: Effects of cortisol. Endocrinology, 132, pp. 2083-2089.
37. Liu, F., Powell, DR, Styne, DM and Hintz, RL (1991) Insulin-like growth factors (IGFs) and IGF-binding proteins in the developing rhesus monkey. J Clin Endocrinol Metab, 72, pp. 905-911.
38. Martin, MA, Serradas, P., Ramos, S., Fernandez, E., Goya, L., Gangnerau, MN, Lacorne, M., Pascual-Leone, AM, Escriva, F., Portha, B. and Alvarez, C. (2005) Protein-caloric food restriction affects insulin-like growth factor system in foetal Wistar rat. Endocrinology, 146, pp. 1364-1371.
39. McCusker, RH and Clemmons, DR (1992) The insulin-like growth factor binding proteins: Structure and biological functions. The insulin-like growth factors. Structure and biological functions, p. 110. Oxford University Press., Oxford
40. Meng, W., Lahrssen-Wiederholt, M. and Dänicke, S. (2006) Undesirable substances in animal nutrition-minimizing is possible. Kraftfutter/Feed Mag, 1206, pp. 26-33.
41. Monaco, MH and Donovan, SM (1996) Moderate food restriction abolishes the pregnancy-associated rise in serum growth hormone and decreases serum insulin-like growth factor-I (IGF-I) concentrations without altering IGF-I mRNA expression in rats. J Nutr, 126, pp. 544-553.
42. Murphy, LJ, Bell, GI and Friesen, HG (1987) Tissue distribution of insulin-like growth factor I and II messenger ribonucleic acid in the adult rat. Endocrinology, 120, pp. 1279-1282.
43. Ohlsson, C., Sjogren, K., Jansson, JO and Isaksson, OG (2000) The relative importance of endocrine versus autocrine/paracrine insulin-like growth factor-I in the regulation of body growth. Pediatr Nephrol, 14, pp. 541-543.
44. Olausson, H. and Sohlstrom, A. (2003) Effects of food restriction and pregnancy on the expression of insulin-like growth factors-I and -II in tissues from guinea pigs. J Endocrinol, 179, pp. 437-445.
45. Pell, JM, Saunders, JC and Gilmour, RS (1993) Differential regulation of transcription initiation from insulin-like growth factor-I (IGF-I) leader exons and of tissue IGF-I expression in response to changed growth hormone and nutritional status in sheep. Endocrinology, 132, pp. 1797-1807.
46. Peng, M., Pelletier, G., Palin, MF, Veronneau, S., LeBel, D. and Abribat, T. (1996) Ontogeny of IGFs and IGFBPs mRNA levels and tissue concentrations in liver, kidney and skeletal muscle of pig. Growth Dev Aging, 60, pp. 171-187.
47. Persson, E., Sahlin, L., Masironi, B., Dantzer, V., Eriksson, H. and Rodriguez-Martinez, H. (1997) Insulin-like growth factor-I in the porcine endometrium and placenta: Localization and concentration in relation to steroid influence during early pregnancy. Anim Reprod Sci, 46, pp. 261-281.
48. Sara, VR and Hall, K. (1990) Insulin-like growth factors and their binding proteins. Physiol Rev, 70, pp. 591-614.
49. Silha, JV and Murphy, LJ (2002) Insights from insulin-like growth factor binding protein transgenic mice. Endocrinology, 143, pp. 3711-3714.
50. Simmen, FA, Badinga, L., Green, ML, Kwak, I., Song, S. and Simmen, RC (1998) The porcine insulin-like growth factor system: At the interface of nutrition, growth and reproduction. J Nutr, 128, pp. 315S-320S.
51. Sterle, JA, Boyd, C., Peacock, JT, Koenigsfeld, AT, Lamberson, WR, Gerrard, DE and Lucy, MC (1998) Insulin-like growth factor (IGF)-I, IGF-II, IGF-binding protein-2 and pregnancy-associated glycoprotein mRNA in pigs with somatotropin-enhanced foetal growth. J Endocrinol, 159, pp. 441-450.
52. Thissen, JP, Ketelslegers, JM and Underwood, LE (1994) Nutritional regulation of the insulin-like growth factors. Endocr Rev, 15, pp. 80-101.
53. Tiemann, U., Brüssow, KP, Küchenmeister, U., Jonas, L., Pohland, R., Reischauer, A., Jäger, K. and Dänicke, S. (2008) Changes in the spleen and liver of pregnant sows and full-term piglets after feeding diets naturally contaminated with deoxynivalenol and zearalenone. Vet J., 176, pp. 188-196.
54. Tiemann, U. and Danicke, S. (2007) In vivo and in vitro effects of the mycotoxins zearalenone and deoxynivalenol on different non-reproductive and reproductive organs in female pigs: A review. Food Addit Contam, 24, pp. 306-314.