Development and characterization of solid lipid microparticles loaded with ascorbic acid and produced by spray congealing

Food Research International

Volumn 67, Issue , 2015, Pages 52-59

  Matos Jr, Fernando Eustáquio ^a   Di Sabatino, Marcello ^b   Passerini, Nadia ^b   Favaro Trindade, Carmen Sílvia ^a   Albertini, Beatrice ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Encapsulation efficiency; Spray chilling; Spray cooling; Stability; Vitamin C

Indexed keywords

CARRIER CONCENTRATION; CONVERGENCE OF NUMERICAL METHODS; EFFICIENCY; ENCAPSULATION; FOOD STORAGE; OILS AND FATS; PALM OIL; STABILITY;

ENCAPSULATION EFFICIENCY; GLYCEROL MONOSTEARATE; HYDROGENATED PALM OIL; LIPID MICROPARTICLES; SPRAY COOLING; STORAGE TEMPERATURES; THERMAL BEHAVIORS; VITAMIN C;

ASCORBIC ACID;

EID: 84911878623     PISSN: 09639969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodres.2014.11.002     Document Type: Article

References (36)

1. Abbas S., Weia C., Hayatb K., Xiaominga Z. Ascorbic acid: Microencapsulation techniques and trends - A review. Food Reviews International 2012, 28(4):343-374.
2. Albertini B., Passerini N., Di Sabatino M., Vitali B., Brigidi P., Rodriguez L. Polymer-lipid based mucoadhesive microspheres prepared by spray-congealing for the vaginal delivery of econazole nitrate. European Journal of Pharmaceutical Sciences 2009, 36(4):591-601.
3. Albertini B., Passerini N., Pattarino F., Rodriguez L. New spray congealing atomizer for the microencapsulation of highly concentrated solid and liquid substances. European Journal of Pharmaceutics and Biopharmaceutics 2008, 69(1):348-357.
4. Alvim I.D., Souza F.S., Koury I.P., Jurt T., Dantas F.B.H. Use of the spray chilling method to deliver hydrophobic components: Physical characterization of microparticles. Food Science and Technology 2013, 33(1):34-39.
5. Arshady R. Microcapsules for food. Journal of Microencapsulation 1993, 10(4):413-435.
6. Chambi H.N.M., Alvim I.D., Barrea-Arellano D., Grosso C.R.F. Solid lipid microparticles containing water-soluble compounds of different molecular mass: Production, characterization and release profiles. Food Research International 2008, 41:229-236.
7. Chang D., Abbas S., Hayat K., Xia S., Zhang X., Xie M., et al. Encapsulation of ascorbic acid in amorphous maltodextrin employing extrusion as affected by matrix/core ratio and water content. International Journal of Food Science and Technology 2010, 45:1895-1901.
8. Comunian T.A., Abbaspourrad A., Favaro-Trindade C.S., Weitz D.A. Fabrication of solid lipid microcapsules containing ascorbic acid using a microfluidic technique. Food Chemistry 2014, 152:271-275.
9. Comunian T.A., Thomazini M., Alves A.J.G., Matos Junior F.E., Balieiro J.C.C., Favaro-Trindade C.S. Microencapsulation of ascorbic acid by complex coacervation: Protection and controlled release. Food Research International 2013, 52(1):373-379.
10. Desai K.G.H., Liu C., Park H.J. Characteristics of vitamin C immobilized particles and sodium alginate beads containing immobilized particles. Journal of Microencapsulation 2005, 22:363-376.
11. Di Sabatino M., Albertini B., Kett W.L., Passerini N. Spray congealed lipid microparticles with high protein loading: Preparation and solid state characterisation. European Journal of Pharmaceutical Sciences 2012, 46(5):346-356.
12. Esposito E., Cervellati F., Menegatti E., Nastruzzi C., Cortesi R. Spray dried Eudragit microparticles as encapsulation devices for vitamin C. International Journal of Pharmaceutics 2002, 242:329-334.
13. Farajzadeh M.A., Nagizadeh S. A simple and reliable spectrophotometric method for the determination of ascorbic acid in pharmaceutical preparations. Journal of Analytical Chemistry 2003, 58(10):927-932.
14. Fennema O.R., Damodaran S., Parkin K.L. Fennema's food chemistry 2010, Artmed, Porto Alegre. 4th ed.
15. Gavory C., Abderrahmen R., Bordes C., Chaussy D., Belgacem M.N., Fessi H., et al. Encapsulation of a pressure sensitive adhesive by spray-cooling: Optimum formulation and processing conditions. Advanced Powder Technology 2014, 25(1):292-300.
16. Ilić I., Dreua R., Burjakb M., Homarb M., Kerča J., Srčiča S. Microparticle size control and glimepiride microencapsulation using spray congealing technology. International Journal of Pharmaceutics 2009, 381(2):176-183.
17. Killeen M.J. Spray drying and spray congealing in pharmaceutics. Encyclopedia of Pharmaceutical Technology 1996, vol. 14:207-221. Marcel Dekker Inc., New York. J.C. Boylan, J. Swarbrick (Eds.).
18. Kim H.H.Y., Baianu I.C. Novel liposome microencapsulation techniques for food applications. Trends in Food Science & Technology 1991, 2:55-61.
19. Kirby C., Whittle C., Rigby N., Coxon D., Law B. Stabilization of ascorbic acid by microencapsulation in liposomes. International Journal of Food Science and Technology 1991, 26:437-449.
20. Knezevic Z., Gosak D., Hraste M., Jalsenjako I. Fluid-bed microencapsulation of ascorbic acid. Journal of Microencapsulation 1998, 15:237-252.
21. Lee J.B., Ahn J., Lee J., Kwak H.S. Ascorbic acid microencapsulated with polyglycerol monostearate for milk fortification. Bioscience, Biotechnology, and Biochemistry 2004, 68:495-500.
22. Leonel A.J., Chambi H.N.M., Barrera-Arellano D., Pastore H.O., Grosso C.R.F. Production and characterization of lipid microparticles produced by spray cooling encapsulating a low molar mass hydrophilic compound. Food Science and Technology 2010, 30(1):276-281.
23. Leusner, S., Lakkis, J., Van Lengerich, B.H. & Jarl, T. (2002). Oligosaccharide encapsulated mineral and vitamin ingredients. U.S. Patent, October 22: 6468568.
24. Maschke A., Becker C., Eyrich D., Kiermaier J., Blunk T., Gopferich A. Development of a spray congealing process for the preparation of insulin-loaded lipid microparticles and characterization thereof. European Journal of Pharmaceutics and Biopharmaceutics 2007, 65:175-187.
25. Okuro P.K., Thomazini M., Balieiro J.C.C., Liberal R.D.C.O., Fávaro-Trindade C.S. Co-encapsulation of Lactobacillus acidophilus with inulin or polydextrose in solid lipid microparticles provides protection and improves stability. Food Research International 2013, 53(1):96-103.
26. Passerini N., Perissutti B., Albertini B., Franceschinis E., Lenaz D., Hasa D., et al. A new approach to enhance oral bioavailability of Silybum marianum dry extract: Association of mechanochemical activation and spray congealing. Phytomedicine 2012, 19(2):160-168.
27. Passerini N., Perissutti B., Moneghini M., Voinovich D., Albertini B., Cavallari C., et al. Characterization of carbamazepine-Gelucire 50/13 microparticles prepared by a spray-congealing process using ultrasounds. Journal Pharmaceutical Sciences 2002, 91:699-707.
28. Pedroso D.L., Thomazini M., Heinemann J.B., Favaro-Trindade C.S. Protection of Bifidobacterium lactis and Lactobacillus acidophilus by microencapsulation using spray-chilling. International Dairy Journal 2012, 26(2):127-132.
29. Pereira H.V.R., Saraiva K.P., Carvalho L.M.J., Andrade L.R., Pedrosa C., Pierucci A. Legumes seeds protein isolates in the production of ascorbic acid microparticles. Food Research International 2009, 42:115-121.
30. Righetto A.M., Netto F.M. Vitamin C stability in encapsulated green west Indian cherry juice and in encapsulated synthetic ascorbic acid. Journal of Science and Food Agricultural 2006, 86:1202-1208.
31. Rocha G.A., Trindade M.A., Netto F.M., Favaro-Trindade C.S. Microcapsules of a casein hydrolysate: production, characterization, and application in protein bars. Food Science and Technology International 2009, 15(4):407-413.
32. Rozman B., Gasperlin M. Stability of vitamins C and E in topical microemulsions for combined antioxidant therapy. Drug Delivery 2007, 14(4):235-245.
33. Sharma R., Lal D. Fortification of milk with microencapsulated vitamin C and its thermal stability. Journal of Food Science and Technology 2005, 42:191-194.
34. Trindade M.A., Grosso C.R.F. The stability of ascorbic acid microencapsulated in granules of rice starch and in gum Arabic. Journal of Microencapsulation 2000, 17(2):169-176.
35. Uddin M.S., Hawlader M.N., Zhu H.J. Microencapsulation of ascorbic acid: Effect of process variables on product characteristics. Journal of Microencapsulation 2001, 18:199-209.
36. Wechtersbach L., Polak T., Ulrih N.P., Cigić B. Stability and transformation of products formed from dimeric dehydroascorbic acid at low pH. Food Chemistry 2011, 119(3):965-973.