Synthesis and biological evaluation of piperlongumine derivatives as potent anti-inflammatory agents

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 24, 2014, Pages 5727-5730

  Seo, Young Hwa ^a   Kim, Jin Kyung ^b   Jun, Jong Gab ^a  

^a Hallym University   (South Korea)

^b Catholic University of Daegu   (South Korea)

Author keywords

Anti inflammatory; Keyword 3,4,5 Trimethoxycinnamic acid; Nitric oxide; Piperlongumine

Indexed keywords

2 PYRROLIDINONE; ANTIINFLAMMATORY AGENT; LIPOPOLYSACCHARIDE; PIPERLONGUMINE DERIVATIVE; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; NITRIC OXIDE; PIPERLONGUMININE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG POTENCY; DRUG POTENTIATION; DRUG SCREENING; DRUG SYNTHESIS; MACROPHAGE; ANIMAL; CELL CULTURE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMICALLY INDUCED; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; EVALUATION STUDY; INFLAMMATION; METABOLISM; MOUSE; SYNTHESIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL PROLIFERATION; CELLS, CULTURED; DIOXOLANES; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MOLECULAR STRUCTURE; NITRIC OXIDE;

EID: 84911872862     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.10.054     Document Type: Article

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