Synthesis of licochalcone analogues with increased anti-inflammatory activity

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 1, 2014, Pages 181-185

  Kim, Si Jun ^a   Kim, Cheol Gi ^a   Yun, So Ra ^a   Kim, Jin Kyung ^b   Jun, Jong Gab ^a  

^a Hallym University   (South Korea)

^b Catholic University of Daegu   (South Korea)

Author keywords

3,3 Sigmatropic rearrangement; anti Inflammatory effects; IC50 values of NO production; Licohalcone B; Licohalcone D

Indexed keywords

4 HYDROXYACETOPHENONE; ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LICOCHALCONE DERIVATIVE; NITRIC OXIDE; PLANT MEDICINAL PRODUCT; RESORCINOL; UNCLASSIFIED DRUG; CATECHOL; CHALCONE DERIVATIVE; ECHINATIN; ISOLIQUIRITIGENIN; LICOCHALCONE A; LICOCHALCONE B; LICOCHALCONE C; LICOCHALCONE D;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY ASSAY; CLAISEN REARRANGEMENT; CONCENTRATION RESPONSE; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; GLYCYRRHIZA GLABRA; IC 50; NONHUMAN; OXIDATION; PLANT ROOT; BIOLOGICAL ACTIVITY; DEGRANULATION; HYDROGEN BOND; IC50;

ANTI-INFLAMMATORY EFFECTS; IC(50) VALUES OF NO PRODUCTION; LICOHALCONE B; LICOHALCONE D; [3,3]-SIGMATROPIC REARRANGEMENT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL PROLIFERATION; CELL SURVIVAL; CHALCONES; DOSE-RESPONSE RELATIONSHIP, DRUG; MAST CELLS; MOLECULAR STRUCTURE; NITRIC OXIDE; RATS;

EID: 84891481644     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.11.044     Document Type: Article

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