Therapeutic potential of thiazolidinedione-8 as an antibiofilm agent against Candida albicans

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Feldman, Mark ^a   Al Quntar, Abed ^a,b   Polacheck, Itzhak ^c   Friedman, Michael ^b   Steinberg, Doron ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIFUNGAL AGENT; GREEN FLUORESCENT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; THIAZOLIDINEDIONE 8; UNCLASSIFIED DRUG; FUNGAL PROTEIN;

ALS3 GENE; ANIMAL CELL; ANTIADHESION ACTIVITY; ANTIBIOFILM ACTIVITY; ARTICLE; BIOFILM; CANDIDA ALBICANS; CELL ADHESION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CPH1 GENE; CST20 GENE; DOWN REGULATION; DRUG ACTIVITY; EAP1 GENE; FLUORESCENCE MICROSCOPY; FUNGAL CELL WALL; FUNGAL GENE; FUNGUS HYPHAE; GENE EXPRESSION; HST 7 GENE; HWP1 GENE; HYDROPHOBICITY; MACROPHAGE; MAMMAL CELL; MINIMUM INHIBITORY CONCENTRATION; MORPHOGENESIS; MOUSE; NONHUMAN; NRG1 GENE; PATHOGEN CLEARANCE; QUORUM SENSING; RAS1 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUP1 GENE; UME6 GENE; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; PHYSIOLOGY;

ANIMALS; BIOFILMS; CANDIDA ALBICANS; CELL LINE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; MICE; THIAZOLIDINEDIONES;

EID: 84900421811     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093225     Document Type: Article

References (48)

1. Nadǎş GC, Taulescu MA, Ciobanu L, Fiţ NI, Flore C, et al. (2013) The interplay between NSAIDs and Candida albicans on the gastrointestinal tract of guinea pigs. Mycopathology 175: 221-230.
2. Pereira CA, Toledo BC, Santos CT, Pereira Costa AC, Back-Brito GN, et al. (2013) Opportunistic microorganisms in individuals with lesions of denture stomatitis. Diagn Microbiol Infect Dis 76: 419-424.
3. Pfaller MA, Diekema DJ (2007) Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev 20: 133-163. (Pubitemid 46167771)
4. Mayer FL, Wilson D, Hube B (2013) Candida albicans pathogenicity mechanisms. Virulence 4: 119-128.
5. Wachtler B, Wilson D, Haedicke K, Dalle F, Hube B (2011) From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells. PLoS One 6: e17046.
6. Ramage G, Martinez JP, Lopez-Ribot JL (2006) Candida biofilms on implanted biomaterials: a clinically significant problem. FEMS Yeast Res 6: 979-986. (Pubitemid 44568854)
7. Kojic EM, Darouiche RO (2004) Candida infections of medical devices. Clin Microbiol Rev 17: 255-267. (Pubitemid 38534029)
8. Li L, Finnegan MB, Ozkan S, Kim Y, Lillehoj PB, et al. (2010) In vitro study of biofilm formation and effectiveness of antimicrobial treatment on various dental material surfaces. Mol Oral Microbiol 25: 384-390.
9. Nobile CJ, Nett JE, Andes DR, Mitchell AP (2006) Function of Candida albicans adhesin Hwp1 in biofilm formation. Eukaryot Cell 5: 1604-1610. (Pubitemid 44622591)
10. Umeyama T, Kaneko A, Nagai Y, Hanaoka N, Tanabe K, et al. (2005) Candida albicans protein kinase CaHsl1p regulates cell elongation and virulence. Mol Microbiol 55: 381-395. (Pubitemid 40179375)
11. Finkel JS, Mitchell AP (2011) Genetic control of Candida albicans biofilm development. Nat Rev Microbiol 9: 109-118.
12. Blankenship JR, Mitchell AP (2006) How to build a biofilm: a fungal perspective. Curr Opin Microbiol 9: 588-594. (Pubitemid 44791986)
13. Ramage G, Saville SP, Thomas DP, Lopez-Ribot JL (2005) Candida biofilms: an update. Eukaryot Cell 4: 633-638. (Pubitemid 40600417)
14. Srinivasan A, Uppuluri P, Lopez-Ribot J, Ramasubramanian AK (2011) Development of a high-throughput Candida albicans biofilm chip. PLoS One 6: e19036.
15. Ramage G, Rajendran R, Sherry L, Williams C (2012) Fungal biofilm resistance. Int J Microbiol 2012: 528521.
16. Kagan S, Jabbour A, Sionov E, Al-Quntar AA, Steinberg D, et al. (2014) Anti Candida albicans biofilm effect of novel heterocyclic compounds. J Antimicrob Chemother 69: 416-427.
17. Albuquerque P, Casadevall A (2012) Quorum sensing in fungi - a review. Med Mycol 50: 337-345.
18. Nickerson KW, Atkin AL, Hornby JM (2006) Quorum sensing in dimorphic fungi: farnesol and beyond. Appl Environ Microbiol 72: 3805-3813. (Pubitemid 43894839)
19. Ramage G, Saville SP, Wickes BL, Lopez-Ribot JL (2002) Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule. Appl Environ Microbiol 68: 5459-5463. (Pubitemid 35265681)
20. Alem MA, Oteef MD, Flowers TH, Douglas LJ (2006) Production of tyrosol by Candida albicans biofilms and its role in quorum sensing and biofilm development. Eukaryot Cell 5: 1770-1779. (Pubitemid 44622603)
21. Brackman G, Al Quntar AA, Enk CD, Karalic I, Nelis HJ, et al. (2013) Synthesis and evaluation of thiazolidinedione and dioxazaborocane analogues as inhibitors of AI-2 quorum sensing in Vibrio harveyi. Bioorg Med Chem 21: 660-667.
22. Gomes PN, da Silva WJ, Pousa CC, Narvaes EA, Del Bel Cury AA (2011) Bioactivity and cellular structure of Candida albicans and Candida glabrata biofilms grown in the presence of fluconazole. Arch Oral Biol 56: 1274-1281.
23. Weber K, Schulz B, Ruhnke M (2010) The quorum-sensing molecule E, E-farnesol - its variable secretion and its impact on the growth and metabolism of Candida species. Yeast 27: 727-739.
24. Feldman M, Tanabe S, Howell A, Grenier D (2012) Cranberry proanthocyanidins inhibit the adherence properties of Candida albicans and cytokine secretion by oral epithelial cells. BMC Complement Altern Med 12: 6.
25. Martinez LR, Mihu MR, Tar M, Cordero RJ, Han G, et al. (2010) Demonstration of antibiofilm and antifungal efficacy of chitosan against candidal biofilms, using an in vivo central venous catheter model. J Infect Dis 201: 1436-1440.
26. Privett BJ, Nutz ST, Schoenfisch MH (2010) Efficacy of surface-generated nitric oxide against Candida albicans adhesion and biofilm formation. Biofouling 26: 973-983.
27. Ramage G, Vande Walle K, Wickes BL, Lopez-Ribot JL (2001) Standardized method for in vitro antifungal susceptibility testing of Candida albicans biofilms. Antimicrob Agents Chemother 45: 2475-2479. (Pubitemid 32801898)
28. Baillie GS, Douglas LJ (1998) Effect of growth rate on resistance of Candida albicans biofilms to antifungal agents. Antimicrob Agents Chemother 42: 1900-1905. (Pubitemid 28363067)
29. Kojic EM, Darouiche RO (2004) Candida infections of medical devices. Clin Microbiol Rev 17: 255-267. (Pubitemid 38534029)
30. Lo HJ, Kohler JR, DiDomenico B, Loebenberg D, Cacciapuoti A, et al. (1997) Nonfilamentous C. albicans mutants are avirulent. Cell 90: 939-949. (Pubitemid 27381632)
31. Saville SP, Lazzell AL, Monteagudo C, Lopez-Ribot JL (2003) Engineered control of cell morphology in vivo reveals distinct roles for yeast and filamentous forms of Candida albicans during infection. Eukaryot Cell 2: 1053-1060. (Pubitemid 37298719)
32. Lorenz MC, Bender JA, Fink GR (2004) Transcriptional response of Candida albicans upon internalization by macrophages. Eukaryot Cell 3: 1076-1087. (Pubitemid 39385215)
33. Phan QT, Belanger PH, Filler SG (2000) Role of hyphal formation in interactions of Candida albicans with endothelial cells. Infect Immun 68: 3485-3490. (Pubitemid 30340448)
34. Nobile CJ, Mitchell AP (2005) Regulation of cell-surface genes and biofilm formation by the C. albicans transcription factor Bcr1p. Curr Biol 15: 1150-1155. (Pubitemid 40841360)
35. Shareck J, Belhumeur P (2011) Modulation of morphogenesis in Candida albicans by various small molecules. Eukaryot Cell 10: 1004-1012.
36. Hobson RP, Munro CA, Bates S, MacCallum DM, Cutler JE, et al. (2004) Loss of cell wall mannosylphosphate in Candida albicans does not influence macrophage recognition. J Biol Chem 279: 39628-39635. (Pubitemid 39258230)
37. de Souza RD, Mores AU, Cavalca L, Rosa RT, Samaranayake LP, et al. (2009) Cell surface hydrophobicity of Candida albicans isolated from elder patients undergoing denture-related candidosis. Gerodontology 26: 157-161.
38. Coleman DA, Oh SH, Zhao X, Zhao H, Hutchins JT, et al. (2009) Monoclonal antibodies specific for Candida albicans Als3 that immunolabel fungal cells in vitro and in vivo and block adhesion to host surfaces. J Microbiol Methods 78: 71-78.
39. Hoyer LL, Green CB, Oh SH, Zhao X (2008) Discovering the secrets of the Candida albicans agglutinin-like sequence (ALS) gene family - a sticky pursuit. Med Mycol 46: 1-15. (Pubitemid 351298235)
40. Grubb SE, Murdoch C, Sudbery PE, Saville SP, Lopez-Ribot JL, et al. (2008) Candida albicans-endothelial cell interactions: a key step in the pathogenesis of systemic candidiasis. Infect Immun 76: 4370-4377.
41. Sundstrom P (2002) Adhesion in Candida spp. Cell Microbiol 4: 461-469.
42. Banerjee M, Thompson DS, Lazzell A, Carlisle PL, Pierce C, et al. (2008) UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence. Mol Biol Cell 19: 1354-1365. (Pubitemid 351805091)
43. Zeidler U, Lettner T, Lassnig C, Muller M, Lajko R, et al. (2009) UME6 is a crucial downstream target of other transcriptional regulators of true hyphal development in Candida albicans. FEMS Yeast Res 9: 126-142.
44. Oh KB, Miyazawa H, Naito T, Matsuoka H (2001) Purification and characterization of an autoregulatory substance capable of regulating the morphological transition in Candida albicans. Proc Natl Acad Sci U S A 98: 4664-4668. (Pubitemid 32295033)
45. Sato T, Watanabe T, Mikami T, Matsumoto T (2004) Farnesol, a morphogenetic autoregulatory substance in the dimorphic fungus Candida albicans, inhibits hyphae growth through suppression of a mitogen-activated protein kinase cascade. Biol Pharm Bull 27: 751-752. (Pubitemid 41694687)
46. Roman E, Alonso-Monge R, Gong Q, Li D, Calderone R, et al. (2009) The Cek1 MAPK is a short-lived protein regulated by quorum sensing in the fungal pathogen Candida albicans. FEMS Yeast Res 9: 942-955.
47. Braun BR, Johnson AD (1997) Control of filament formation in Candida albicans by the transcriptional repressor TUP1. Science 277: 105-109. (Pubitemid 27450657)
48. Gerami-Nejad M, Zacchi LF, McClellan M, Matter K, Berman J (2013) Shuttle vectors for facile gap repair cloning and integration into a neutral locus in Candida albicans. Microbiology 159: 565-579.