Emerging themes in cryptococcal capsule synthesis

Current Opinion in Structural Biology

Volumn 21, Issue 5, 2011, Pages 597-602

  Kumar, Pardeep ^a   Yang, Meng ^a   Haynes, Brian C ^a   Skowyra, Michael L ^a   Doering, Tamara L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; GLUCURONOXYLOMANNAN; GLUCURONOXYLOMANNOGALACTAN; POLYSACCHARIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CIR1; UNCLASSIFIED DRUG;

BIOSYNTHESIS; CARBOHYDRATE ANALYSIS; CRYPTOCOCCUS NEOFORMANS; CRYTOCOCCAL CAPSULE; FUNGAL VIRULENCE; FUNGUS GROWTH; MEMBRANE; MEMBRANE FORMATION; MEMBRANE PERMEABILITY; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL; REVIEW; RNA SEQUENCE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

CELL MEMBRANE; CELL WALL; CRYPTOCOCCUS NEOFORMANS; FUNGAL PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; MICROSCOPY, ELECTRON; POLYMERS; POLYSACCHARIDES; SIGNAL TRANSDUCTION; VIRULENCE FACTORS;

FILOBASIDIELLA NEOFORMANS;

EID: 80053568187     PISSN: 0959440X     EISSN: 1879033X     Source Type: Journal    
DOI: 10.1016/j.sbi.2011.08.006     Document Type: Review

References (48)

1. Park B.J., Wannemuehler K.A., Marston B.J., Govender N., Pappas P.G., Chiller T.M. Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. Aids 2009, 23:525-530.
2. Sanfelice F. Contributo alla morfologia e biologia dei blastomiceti che si sviluppano nei succhi de alcuni frutti. Ann Ist Ig R Univ Roma 1894, 4:463-469.
3. Busse O. Uber parasitare Zelleinschlusse und ihre Zuchtung. Centralbl Bakt Parasit 1894, 16:175-180.
4. Klutts J.S., Doering T.L. Cryptococcal xylosyltransferase 1 (Cxt1p) from Cryptocooccus neoformans plays a direct role in the synthesis of capsule polysaccharides. J Biol Chem 2008, 283:14327-14334.
5. Klutts J.S., Yoneda A., Reilly M.C., Bose I., Doering T.L. Glycosyltransferases and their products: cryptococcal variations on fungal themes. FEMS Yeast Res 2006, 6:499-512.
6. Yoneda A., Doering T.L. A eukaryotic capsular polysaccharide is synthesized intracellularly and secreted via exocytosis. Mol Biol Cell 2006, 17:5131-5140.
7. Panepinto J., Komperda K., Frases S., Park Y.D., Djordjevic J.T., Casadevall A., Williamson P.R. Sec6-dependent sorting of fungal extracellular exosomes and laccase of Cryptococcus neoformans. Mol Microbiol 2009, 71:1165-1176.
8. Rodrigues M.L., Nimrichter L., Oliveira D.L., Frases S., Miranda K., Zaragoza O., Alvarez M., Nakouzi A., Feldmesser M., Casadevall A. Vesicular polysaccharide export in Cryptococcus neoformans is a eukaryotic solution to the problem of fungal trans-cell wall transport. Eukaryot Cell 2007, 6:48-59.
9. Doering T.L. How sweet it is! Capsule formation and cell wall biogenesis in Cryptococcus neoformans. Ann Rev Microbiol 2009, 63:223-247.
10. Rodrigues M.L., Fonseca F.L., Frases S., Casadevall A., Nimrichter L. The still obscure attributes of cryptococcal glucuronoxylomannan. Med Mycol 2009, 47:783-788.
11. Janbon G., Doering T.L. Biosynthesis and genetics of the Cryptococcus capsule. Cryptococcus, From Human Pathogen to Model Yeast 2011, 27-41. ASM Press. J. Heitman, T.R. Kozel, J. Kwon-Chung, J. Perfect, A. Casadevall (Eds.).
12. Rodrigues M.L., Casadevall A., Zaragoza O. The architecture and antigenic composition of the polysaccharide capsule. Cryptococcus, From Human Pathogen to Model Yeast 2011, 43-54. ASM Press. J. Heitman, T.R. Kozel, J. Kwon-Chung, J. Perfect, A. Casadevall (Eds.).
13. Heitman J., Kozel T.R., Kwon-Chung J., Perfect J., Casadevall A. Cryptococcus, From Human Pathogen to Model Yeast 2011, ASM Press, Washington, D.C.
14. 1H nuclear magnetic resonance spectra of glucuronoxylomannans with a computer-simulated artificial neural network. Clin Diagn Lab Immunol 1998, 5:146-159.
15. Oliveira D.L., Nimrichter L., Miranda K., Frases S., Faull K.F., Casadevall A., Rodrigues M.L. Cryptococcus neoformans cryoultramicrotomy and vesicle fractionation reveals an intimate association between membrane lipids and glucuronoxylomannan. Fungal Genet Biol 2009, 46:956-963.
16. Heiss C., Klutts J.S., Wang Z., Doering T.L., Azadi P. The structure of Cryptococcus neoformans galactoxylomannan contains beta-d-glucuronic acid. Carbohydr Res 2009, 344:915-920.
17. Vaishnav V.V., Bacon B.E., O'Neill M., Cherniak R. Structural characterization of the galactoxylomannan of Cryptococcus neoformans Cap67. Carbohydr Res 1998, 306:315-330.
18. De Jesus M., Nicola A.M., Rodrigues M.L., Janbon G., Casadevall A. Capsular localization of the Cryptococcus neoformans polysaccharide component galactoxylomannan. Eukaryot Cell 2009, 8:96-103.
19. Zaragoza O., Rodrigues M.L., De Jesus M., Frases S., Dadachova E., Casadevall A. The capsule of the fungal pathogen Cryptococcus neoformans. Adv Appl Microbiol 2009, 68:133-216.
20. Yoneda A., Doering T.L. Regulation of Cryptococcus neoformans capsule size is mediated at the polymer level. Eukaryot Cell 2008, 7:546-549.
21. Frases S., Pontes B., Nimrichter L., Viana N.B., Rodrigues M.L., Casadevall A. Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules. Proc Natl Acad Sci USA 2009, 106:1228-1233.
22. Jain N., Fries B.C. Phenotypic switching of Cryptococcus neoformans and Cryptococcus gattii. Mycopathologia 2008, 166:181-188.
23. Cordero R.J., Frases S., Guimaraes A.J., Rivera J., Casadevall A. Evidence for branching in cryptococcal capsular polysaccharides and consequences on its biological activity. Mol Microbiol 2011, 79:1101-1117.
24. Gates-Hollingsworth M.A., Kozel T.R. Phenotypic heterogeneity in expression of epitopes in the Cryptococcus neoformans capsule. Mol Microbiol 2009, 74:126-138.
25. Pierini L.M., Doering T.L. Spatial and temporal sequence of capsule construction in Cryptococcus neoformans. Mol Microbiol 2001, 41:105-115.
26. Charlier C., Chretien F., Baudrimont M., Mordelet E., Lortholary O., Dromer F. Capsule structure changes associated with Cryptococcus neoformans crossing of the blood-brain barrier. Am J Pathol 2005, 166:421-432.
27. De Jesus M., Chow S.K., Cordero R.J., Frases S., Casadevall A. Galactoxylomannans from Cryptococcus neoformans varieties neoformans and grubii are structurally and antigenically variable. Eukaryot Cell 2010, 9:1018-1028.
28. Gates M.A., Thorkildson P., Kozel T.R. Molecular architecture of the Cryptococcus neoformans capsule. Mol Microbiol 2004, 52:13-24.
29. Frases S., Pontes B., Nimrichter L., Rodrigues M.L., Viana N.B., Casadevall A. The elastic properties of the Cryptococcus neoformans capsule. Biophys J 2009, 97:937-945.
30. Nimrichter L., Frases S., Cinelli L.P., Viana N.B., Nakouzi A., Travassos L.R., Casadevall A., Rodrigues M.L. Self-aggregation of Cryptococcus neoformans capsular glucuronoxylomannan is dependent on divalent cations. Eukaryot Cell 2007, 6:1400-1410.
31. Vincken J.P., Schols H.A., Oomen R.J., McCann M.C., Ulvskov P., Voragen A.G., Visser R.G. If homogalacturonan were a side chain of rhamnogalacturonan I. Implications for cell wall architecture. Plant Physiol 2003, 132:1781-1789.
32. Reese A.J., Doering T.L. Cell wall alpha-1,3-glucan is required to anchor the Cryptococcus neoformans capsule. Mol Microbiol 2003, 50:1401-1409.
33. Reese A.J., Yoneda A., Breger J.A., Beauvais A., Liu H., Griffith C.L., Bose I., Kim M.J., Skau C., Yang S., et al. Loss of cell wall alpha(1-3) glucan affects Cryptococcus neoformans from ultrastructure to virulence. Mol Microbiol 2007, 63:1385-1398.
34. Gilbert N.M., Donlin M.J., Gerik K.J., Specht C.A., Djordjevic J.T., Wilson C.F., Sorrell T.C., Lodge J.K. KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans. Mol Microbiol 2010, 76:517-534.
35. Chang Y.C., Kwon-Chung K.J. Complementation of a capsule-deficient mutation of Cryptococcus neoformans restores its virulence. Mol Cell Biol 1994, 14:4912-4919.
36. Janbon G., Himmelreich U., Moyrand F., Improvisi L., Dromer F. Cas1p is a membrane protein necessary for the O-acetylation of the Cryptococcus neoformans capsular polysaccharide. Mol Microbiol 2001, 42:453-467.
37. Liu O.W., Chun C.D., Chow E.D., Chen C., Madhani H.D., Noble S.M. Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans. Cell 2008, 135:174-188.
38. Alspaugh J.A., Nichols C.B., Xue C., Shen W.-C., Wang P. G-protein signaling pathways: regulating morphogenesis and virulence of Cryptococcus. Cryptococcus, From Human Pathogen to Model Yeast 2011, 153-166. ASM Press. J. Heitman, T.R. Kozel, J. Kwon-Chung, J. Perfect, A. Casadevall (Eds.).
39. Idnurm A., Bahn Y.S., Shen W.C., Rutherford J.C., Muhlschlegel F.A. Sensing extracellular signals in Cryptococcus neoformans. Cryptococcus, From Human Pathogen to Model Yeast 2011, 175-188. ASM Press. J. Heitman, T.R. Kozel, J. Kwon-Chung, J. Perfect, A. Casadevall (Eds.).
40. Kozubowski L., Lee S.C., Heitman J. Signalling pathways in the pathogenesis of Cryptococcus. Cell Microbiol 2009, 11:370-380.
41. Cramer K.L., Gerrald Q.D., Nichols C.B., Price M.S., Alspaugh J.A. Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans. Eukaryot Cell 2006, 5:1147-1156.
42. Jung W.H., Sham A., White R., Kronstad J.W. Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans. PLoS Biol 2006, 4:e410.
43. Chun C.D., Brown J.C., Madhani H.D. A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans. Cell Host Microbe 2011, 9:243-251.
44. Lee H., Chang Y.C., Varma A., Kwon-Chung K.J. Regulatory diversity of TUP1 in Cryptococcus neoformans. Eukaryot Cell 2009, 8:1901-1908.
45. O'Meara T.R., Hay C., Price M.S., Giles S., Alspaugh J.A. Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host. Eukaryot Cell 2010, 9:1193-1202.
46. O'Meara T.R., Norton D., Price M.S., Hay C., Clements M.F., Nichols C.B., Alspaugh J.A. Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule. PLoS Pathog 2010, 6:e1000776.
47. Jung W.H., Saikia S., Hu G., Wang J., Fung C.K., D'Souza C., White R., Kronstad J.W. HapX positively and negatively regulates the transcriptional response to iron deprivation in Cryptococcus neoformans. PLoS Pathog 2010, 6:e1001209.
48. Koutelou E., Hirsch C.L., Dent S.Y. Multiple faces of the SAGA complex. Curr Opin Cell Biol 2010, 22:374-382.