Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans

PLoS Pathogens

Volumn 3, Issue 6, 2007, Pages 0835-0848

  Xu, Deming ^a   Jiang, Bo ^a   Ketela, Troy ^b   Lemieux, Sebastien ^c   Veillette, Karynn ^a   Martel, Nick ^a   Davison, John ^a   Sillaots, Susan ^a   Trosok, Steve ^a   Bachewich, Catherine ^d   Bussey, Howard ^e   Youngman, Phil ^f   Roemer, Terry ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b Infinity Pharmaceuticals Inc   (United States)

^c INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^d Gina Cody School of Engineering and Computer Science   (Canada)

^e MCGILL UNIVERSITY   (Canada)

^f MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; AMPHOTERICIN B; ANTIFUNGAL AGENT; AUREOBASIDIN A; BENOMYL; BREFELDIN A; CASPOFUNGIN; CERULENIN; CLOTRIMAZOLE; CYTOCHALASIN D; DYCLONINE; ECONAZOLE; ERGOSTEROL; FATTY ACID; FLUCONAZOLE; FLUCYTOSINE; FLUOROURACIL; KETOCONAZOLE; MEVINOLIN; NOCODAZOLE; RADICICOL; RORIDIN A; SPHINGOLIPID; SULCONAZOLE; TERBINAFINE; TUBERCIDIN; TUNICAMYCIN; UNINDEXED DRUG; VERRUCARIN A; VORICONAZOLE; FUNGAL DNA; MESSENGER RNA;

ARTICLE; CANDIDA ALBICANS; CHEMICAL GENETICS; CONTROLLED STUDY; DELETION MUTANT; DIPLOIDY; DRUG MECHANISM; DRUG SCREENING; DRUG TARGETING; FATTY ACID SYNTHESIS; FITNESS EVALUATION; FOOD AND DRUG ADMINISTRATION; GENE CONSTRUCT; GENE IDENTIFICATION; GENE INTERACTION; GENE LIBRARY; GENOME ANALYSIS; GLYCOSYLATION; NONHUMAN; PROTEIN FOLDING; RNA PROCESSING; RNA TRANSLATION; DNA MICROARRAY; DRUG DESIGN; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GENOME; METABOLISM; MICROBIOLOGICAL EXAMINATION;

CANDIDA ALBICANS;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; DNA, FUNGAL; DRUG DESIGN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; GENOME, FUNGAL; MICROBIAL SENSITIVITY TESTS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA, MESSENGER;

EID: 34347344011     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0030092     Document Type: Article

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