-
1
-
-
0037180768
-
The immunopathogenesis of sepsis
-
Cohen, J. (2002) The immunopathogenesis of sepsis. Nature 420, 885-891
-
(2002)
Nature
, vol.420
, pp. 885-891
-
-
Cohen, J.1
-
2
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai, T., and Akira, S. (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11, 373-384
-
(2010)
Nat. Immunol.
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
3
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
Medzhitov, R. (2007) Recognition of microorganisms and activation of the immune response. Nature 449, 819-826
-
(2007)
Nature
, vol.449
, pp. 819-826
-
-
Medzhitov, R.1
-
4
-
-
33845497181
-
Inflammatory caspases and inflam- masomes: Master switches of inflammation
-
Martinon, F., and Tschopp, J. (2007) Inflammatory caspases and inflam- masomes: master switches of inflammation. Cell Death Differ. 14, 10-22
-
(2007)
Cell Death Differ.
, vol.14
, pp. 10-22
-
-
Martinon, F.1
Tschopp, J.2
-
5
-
-
84878237993
-
Activation and regulation of the inflammasomes
-
Latz, E., Xiao, T. S., and Stutz, A. (2013) Activation and regulation of the inflammasomes. Nat. Rev. Immunol. 13, 397-411
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 397-411
-
-
Latz, E.1
Xiao, T.S.2
Stutz, A.3
-
6
-
-
70249138036
-
Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NL RP 3 inflammasome activation by regulating NL RP 3 expression
-
Bauernfeind, F. G., Horvath, G., Stutz, A., Alnemri, E. S., MacDonald, K., Speert, D., Fernandes-Alnemri, T., Wu, J., Monks, B. G., Fitzgerald, K. A., Hornung, V., and Latz, E. (2009) Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NL RP 3 inflammasome activation by regulating NL RP 3 expression. J. Immunol. 183, 787-791
-
(2009)
J. Immunol.
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
Wu, J.8
Monks, B.G.9
Fitzgerald, K.A.10
Hornung, V.11
Latz, E.12
-
7
-
-
84858688293
-
Regulation of inflammasome signaling
-
Rathinam, V. A., Vanaja, S. K., and Fitzgerald, K. A. (2012) Regulation of inflammasome signaling. Nat. Immunol. 13, 333-342
-
(2012)
Nat. Immunol.
, vol.13
, pp. 333-342
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Fitzgerald, K.A.3
-
9
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-ß
-
Halle, A., Hornung, V., Petzold, G. C., Stewart, C. R., Monks, B. G., Reinheckel, T., Fitzgerald, K. A., Latz, E., Moore, K. J., and Golenbock, D. T. (2008) The NALP3 inflammasome is involved in the innate immune response to amyloid-ß. Nat. Immunol. 9, 857-865
-
(2008)
Nat. Immunol.
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
10
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung, V., Bauernfeind, F., Halle, A., Samstad, E. O., Kono, H., Rock, K. L., Fitzgerald, K. A., and Latz, E. (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 9, 847-856
-
(2008)
Nat. Immunol.
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
11
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou, R., Yazdi, A. S., Menu, P., and Tschopp, J. (2011) A role for mitochondria in NLRP3 inflammasome activation. Nature 469, 221-225
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
12
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira, K., Haspel, J. A., Rathinam, V. A., Lee, S. J., Dolinay, T., Lam, H. C., Englert, J. A., Rabinovitch, M., Cernadas, M., Kim, H. P., Fitzgerald, K. A., Ryter, S. W., and Choi, A. M. (2011) Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat. Immunol. 12, 222-230
-
(2011)
Nat. Immunol.
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
Fitzgerald, K.A.11
Ryter, S.W.12
Choi, A.M.13
-
13
-
-
84864600268
-
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by Gram-negative bacteria
-
Rathinam, V. A., Vanaja, S. K., Waggoner, L., Sokolovska, A., Becker, C., Stuart, L. M., Leong, J. M., and Fitzgerald, K. A. (2012) TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by Gram-negative bacteria. Cell 150, 606-619
-
(2012)
Cell
, vol.150
, pp. 606-619
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Waggoner, L.3
Sokolovska, A.4
Becker, C.5
Stuart, L.M.6
Leong, J.M.7
Fitzgerald, K.A.8
-
14
-
-
84874768515
-
Noncanonical inflammasomes: Caspase-11 activation and effector mechanisms
-
Broz, P., and Monack, D. M. (2013) Noncanonical inflammasomes: caspase-11 activation and effector mechanisms. PLoS Pathog. 9, e1003144
-
(2013)
Plos Pathog.
, vol.9
, pp. e1003144
-
-
Broz, P.1
Monack, D.M.2
-
15
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki, N., Warming, S., Lamkanfi, M., Van de Walle, L., Louie, S., Dong, J., Newton, K., Qu, Y., Liu, J., Heidens, S., Zhang, J., Lee, W. P., Roose-Girma, M., and Dixit, V. M. (2011) Non-canonical inflammasome activation targets caspase-11. Nature 479, 117-121
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Van De Walle, L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heidens, S.10
Zhang, J.11
Lee, W.P.12
Roose-Girma, M.13
Dixit, V.M.14
-
16
-
-
84867333450
-
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
-
Broz, P., Ruby, T., Belhodne, K., Bouley, D. M., Kayagaki, N., Dixit, V. M., and Monack, D. M. (2012) Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature 490, 288-291
-
(2012)
Nature
, vol.490
, pp. 288-291
-
-
Broz, P.1
Ruby, T.2
Belhodne, K.3
Bouley, D.M.4
Kayagaki, N.5
Dixit, V.M.6
Monack, D.M.7
-
17
-
-
0029808205
-
Identification and characterization of Ich-3, a member of the interleukin-1ß converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE
-
Wang, S., Miura, M., Jung Yk, Zhu, H., Gagliardini, V., Shi, L., Greenberg, A. H., and Yuan, J. (1996) Identification and characterization of Ich-3, a member of the interleukin-1ß converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE. J. Biol. Chem. 271, 20580-20587
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20580-20587
-
-
Wang, S.1
Miura, M.2
Yk, J.3
Zhu, H.4
Gagliardini, V.5
Shi, L.6
Greenberg, A.H.7
Yuan, J.8
-
18
-
-
82755161948
-
Cysteine cathepsins: From structure, function and regulation to new frontiers
-
Turk, V., Stoka, V., Vasiljeva, O., Renko, M., Sun, T., Turk, B., and Turk, D. (2012) Cysteine cathepsins: from structure, function and regulation to new frontiers. Biochim. Biophys. Acta 1824, 68-88
-
(2012)
Biochim. Biophys. Acta
, vol.1824
, pp. 68-88
-
-
Turk, V.1
Stoka, V.2
Vasiljeva, O.3
Renko, M.4
Sun, T.5
Turk, B.6
Turk, D.7
-
19
-
-
72949113082
-
Endolysosomal proteases and their inhibitors in immunity
-
Bird, P. I., Trapani, J. A., and Villadangos, J. A. (2009) Endolysosomal proteases and their inhibitors in immunity. Nat. Rev. Immunol. 9, 871-882
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 871-882
-
-
Bird, P.I.1
Trapani, J.A.2
Villadangos, J.A.3
-
20
-
-
33750984761
-
The role of cystatins in cells of the immune system
-
Kopitar-Jerala, N. (2006) The role of cystatins in cells of the immune system. FEBS Lett. 580, 6295-6301
-
(2006)
FEBS Lett.
, vol.580
, pp. 6295-6301
-
-
Kopitar-Jerala, N.1
-
21
-
-
0038835365
-
Thyropins-new structurally related proteinase inhibitors
-
Lenarcic, B., and Bevec, T. (1998) Thyropins-new structurally related proteinase inhibitors. Biol. Chem. 379, 105-111
-
(1998)
Biol. Chem.
, vol.379
, pp. 105-111
-
-
Lenarcic, B.1
Bevec, T.2
-
22
-
-
52049096824
-
Cystatins: Biochemical and structural properties, and medical relevance
-
Turk, V., Stoka, V., and Turk, D. (2008) Cystatins: biochemical and structural properties, and medical relevance. Front. Biosci. 13, 5406-5420
-
(2008)
Front. Biosci.
, vol.13
, pp. 5406-5420
-
-
Turk, V.1
Stoka, V.2
Turk, D.3
-
23
-
-
0035986219
-
Regulating cysteine protease activity: Essential role of protease inhibitors as guardians and regulators
-
Turk, B., Turk, D., and Salvesen, G. S. (2002) Regulating cysteine protease activity: essential role of protease inhibitors as guardians and regulators. Curr. Pharm. Des. 8, 1623-1637
-
(2002)
Curr. Pharm. Des.
, vol.8
, pp. 1623-1637
-
-
Turk, B.1
Turk, D.2
Salvesen, G.S.3
-
24
-
-
77951237963
-
Stefin B interacts with histones and cathepsin L in the nucleus
-
Ceru, S., Konjar, S., Maher, K., Repnik, U., Krizaj, I., Bencina, M., Renko, M., Nepveu, A., Zerovnik, E., Turk, B., and Kopitar-Jerala, N. (2010) Stefin B interacts with histones and cathepsin L in the nucleus. J. Biol. Chem. 285, 10078-10086
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 10078-10086
-
-
Ceru, S.1
Konjar, S.2
Maher, K.3
Repnik, U.4
Krizaj, I.5
Bencina, M.6
Renko, M.7
Nepveu, A.8
Zerovnik, E.9
Turk, B.10
Kopitar-Jerala, N.11
-
25
-
-
13344269666
-
Mutations in the gene encoding cystatin B in progressive myoclo- nus epilepsy (EPM1)
-
Pennacchio, L. A., Lehesjoki, A. E., Stone, N. E., Willour, V. L., Virtaneva, K., Miao, J., D'Amato, E., Ramirez, L., F ah am, M., Koskiniemi, M., Warrington, J. A., Norio, R., de la Chapelle, A., Cox, D. R., and Myers, R. M. (1996) Mutations in the gene encoding cystatin B in progressive myoclo- nus epilepsy (EPM1). Science 271, 1731-1734
-
(1996)
Science
, vol.271
, pp. 1731-1734
-
-
Pennacchio, L.A.1
Lehesjoki, A.E.2
Stone, N.E.3
Willour, V.L.4
Virtaneva, K.5
Miao, J.6
D'Amato, E.7
Ramirez, L.8
Faham, M.9
Koskiniemi, M.10
Warrington, J.A.11
Norio, R.12
De La Chapelle, A.13
Cox, D.R.14
Myers, R.M.15
-
26
-
-
16944365407
-
Identification of mutations in cystatin B, the gene responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy (EPM1)
-
Lalioti, M. D., Mirotsou, M., Buresi, C., Peitsch, M. C., Rossier, C., Ouazzani, R., Baldy-Moulinier, M., Bottani, A., Malafosse, A., and Antonarakis, S. E. (1997) Identification of mutations in cystatin B, the gene responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy (EPM1). Am. J. Hum. Genet. 60, 342-351
-
(1997)
Am. J. Hum. Genet.
, vol.60
, pp. 342-351
-
-
Lalioti, M.D.1
Mirotsou, M.2
Buresi, C.3
Peitsch, M.C.4
Rossier, C.5
Ouazzani, R.6
Baldy-Moulinier, M.7
Bottani, A.8
Malafosse, A.9
Antonarakis, S.E.10
-
27
-
-
43349093939
-
Molecular background of EPM1-Unverricht-Lundborg disease
-
Joensuu, T., Lehesjoki, A. E., and Kopra, O. (2008) Molecular background of EPM1-Unverricht-Lundborg disease. Epilepsia 49, 557-563
-
(2008)
Epilepsia
, vol.49
, pp. 557-563
-
-
Joensuu, T.1
Lehesjoki, A.E.2
Kopra, O.3
-
28
-
-
0031764610
-
Progressive ataxia, myoclonic epilepsy, and cerebellar apoptosis in cystatin B-deficient mice
-
Pennacchio, L. A., Bouley, D. M., Higgins, K. M., Scott, M. P., Noebels, J. L., and Myers, R. M. (1998) Progressive ataxia, myoclonic epilepsy, and cerebellar apoptosis in cystatin B-deficient mice. Nat. Genet. 20, 251-258
-
(1998)
Nat. Genet.
, vol.20
, pp. 251-258
-
-
Pennacchio, L.A.1
Bouley, D.M.2
Higgins, K.M.3
Scott, M.P.4
Noebels, J.L.5
Myers, R.M.6
-
29
-
-
0043011297
-
Cathepsin B but not cathepsins L or S contributes to the pathogenesis of Unverricht-Lundborg progressive myoclonus epilepsy (EPM1)
-
Houseweart, M. K., Pennacchio, L. A., Vilaythong, A., Peters, C., Noebels, J. L., and Myers, R. M. (2003) Cathepsin B but not cathepsins L or S contributes to the pathogenesis of Unverricht-Lundborg progressive myoclonus epilepsy (EPM1). J. Neurobiol. 56, 315-327
-
(2003)
J. Neurobiol.
, vol.56
, pp. 315-327
-
-
Houseweart, M.K.1
Pennacchio, L.A.2
Vilaythong, A.3
Peters, C.4
Noebels, J.L.5
Myers, R.M.6
-
30
-
-
0036848257
-
New insights into the molecular basis of progressive myoclonus epilepsy: A multiprotein complex with cystatin B
-
Di Giaimo, R., Ricio, M., Santi, S., Galeotti, C., Ambrosetti, D. C., and Melli, M. (2002) New insights into the molecular basis of progressive myoclonus epilepsy: a multiprotein complex with cystatin B. Hum. Mol. Genet. 11, 2941-2950
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2941-2950
-
-
Di Giaimo, R.1
Ricio, M.2
Santi, S.3
Galeotti, C.4
Ambrosetti, D.C.5
Melli, M.6
-
31
-
-
0023876904
-
Analysis of the suppression of IL-1α and IL-1ß production in human peripheral blood mononuclear adherent cells by a glucocorticoid hormone
-
Lew, W., Oppenheim, J. J., and Matsushima, K. (1988) Analysis of the suppression of IL-1α and IL-1ß production in human peripheral blood mononuclear adherent cells by a glucocorticoid hormone. J. Immunol. 140, 1895-1902
-
(1988)
J. Immunol.
, vol.140
, pp. 1895-1902
-
-
Lew, W.1
Oppenheim, J.J.2
Matsushima, K.3
-
32
-
-
77649271201
-
Bone marrow-derived macrophages (BMM): Isolation and applications
-
Weischenfeldt, J., and Porse, B. (2008) Bone marrow-derived macrophages (BMM): isolation and applications. CSH Protoc. 10.1101/ pdb.prot5080
-
(2008)
CSH Protoc.
-
-
Weischenfeldt, J.1
Porse, B.2
-
33
-
-
16344379020
-
Sensitization of stefin B-deficient thymocytes towards staurosporin-induced apoptosis is independent of cysteine cathepsins
-
Kopitar-Jerala, N., Schweiger, A., Myers, R. M., Turk, V., and Turk, B. (2005) Sensitization of stefin B-deficient thymocytes towards staurosporin-induced apoptosis is independent of cysteine cathepsins. FEBS Lett. 579, 2149-2155
-
(2005)
Febs Lett.
, vol.579
, pp. 2149-2155
-
-
Kopitar-Jerala, N.1
Schweiger, A.2
Myers, R.M.3
Turk, V.4
Turk, B.5
-
34
-
-
67449155856
-
Granulysin induces cathepsin B release from lysosomes of target tumor cells to attack mitochondria through processing of bid leading to necroptosis
-
Zhang, H., Zhong, C., Shi, L., Guo, Y., and Fan, Z. (2009) Granulysin induces cathepsin B release from lysosomes of target tumor cells to attack mitochondria through processing of bid leading to necroptosis. J. Immunol. 182, 6993-7000
-
(2009)
J. Immunol.
, vol.182
, pp. 6993-7000
-
-
Zhang, H.1
Zhong, C.2
Shi, L.3
Guo, Y.4
Fan, Z.5
-
35
-
-
84869082555
-
Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics
-
Nekrasov, M., Amrichova, J., Parker, B. J., Soboleva, T. A., Jack, C., Williams, R., Huttley, G. A., and Tremethick, D. J. (2012) Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics. Nat. Struct. Mol. Biol. 19, 1076-1083
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 1076-1083
-
-
Nekrasov, M.1
Amrichova, J.2
Parker, B.J.3
Soboleva, T.A.4
Jack, C.5
Williams, R.6
Huttley, G.A.7
Tremethick, D.J.8
-
36
-
-
84867305334
-
Stage- and gene-specific signatures defined by histones H3K4me2 and H3K27me3 accompany mammalian retina maturation in vivo
-
Popova, E. Y., Xu, X., DeWan, A. T., Salzberg, A. C., Berg, A., Hob, J., Zhang, S. S., and Barnstable, C. J. (2012) Stage- and gene-specific signatures defined by histones H3K4me2 and H3K27me3 accompany mammalian retina maturation in vivo. PLoS One 7, e46867
-
(2012)
Plos One
, vol.7
, pp. e46867
-
-
Popova, E.Y.1
Xu, X.2
DeWan, A.T.3
Salzberg, A.C.4
Berg, A.5
Hob, J.6
Zhang, S.S.7
Barnstable, C.J.8
-
37
-
-
84869432674
-
Cysteine cathepsins are not critical for TRAIL- and CD95-induced apoptosis in several human cancer cell lines
-
Špes, A., Sobotic, B., Turk, V., and Turk, B. (2012) Cysteine cathepsins are not critical for TRAIL- and CD95-induced apoptosis in several human cancer cell lines. Biol. Chem. 393, 1417-1431
-
(2012)
Biol. Chem.
, vol.393
, pp. 1417-1431
-
-
Špes, A.1
Sobotic, B.2
Turk, V.3
Turk, B.4
-
38
-
-
0023079312
-
Endotoxins and disease mechanisms
-
Morrison, D. C., and Ryan, J. L. (1987) Endotoxins and disease mechanisms. Annu. Rev. Med. 38, 417-432
-
(1987)
Annu. Rev. Med.
, vol.38
, pp. 417-432
-
-
Morrison, D.C.1
Ryan, J.L.2
-
39
-
-
0033514959
-
Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1ß are differen-tially regulated in human blood mononuclear cells and mouse spleen cells
-
Puren, A. J., Fantuzzi, G., and Dinarello, C. A. (1999) Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1ß are differen-tially regulated in human blood mononuclear cells and mouse spleen cells. Proc. Natl. Acad. Sci. U.S.A. 96, 2256-2261
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 2256-2261
-
-
Puren, A.J.1
Fantuzzi, G.2
Dinarello, C.A.3
-
40
-
-
0036829675
-
Caspase-11 gene expression in response to lipopolysaccharide and interferon-gamma requires nuclear factor-κB and signal transducer and activator of transcription (STAT) 1
-
Schauvliege, R., Vanrobaeys, J., Schotte, P., and Beyaert, R. (2002) Caspase-11 gene expression in response to lipopolysaccharide and interferon-gamma requires nuclear factor-κB and signal transducer and activator of transcription (STAT) 1.J. Biol. Chem. 277, 41624-41630
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41624-41630
-
-
Schauvliege, R.1
Vanrobaeys, J.2
Schotte, P.3
Beyaert, R.4
-
41
-
-
1942470581
-
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor
-
Goulet, B., Baruch, A., Moon, N. S., Poirier, M., Sansregret, L. L., Erickson, A., Bogyo, M., and Nepveu, A. (2004) A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor. Mol. Cell 14, 207-219
-
(2004)
Mol. Cell
, vol.14
, pp. 207-219
-
-
Goulet, B.1
Baruch, A.2
Moon, N.S.3
Poirier, M.4
Sansregret, L.L.5
Erickson, A.6
Bogyo, M.7
Nepveu, A.8
-
42
-
-
53549094681
-
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation
-
Duncan, E. M., Muratore-Schroeder, T. L., Cook, R. G., Garcia, B. A., Shabanowitz, J., Hunt, D. F., and Allis, C. D. (2008) Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell 135, 284-294
-
(2008)
Cell
, vol.135
, pp. 284-294
-
-
Duncan, E.M.1
Muratore-Schroeder, T.L.2
Cook, R.G.3
Garcia, B.A.4
Shabanowitz, J.5
Hunt, D.F.6
Allis, C.D.7
-
43
-
-
33646886645
-
Cathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin
-
Bulynko, Y. A., Hsing, L. C., Mason, R. W., Tremethick, D. J., and Grigoryev, S. A. (2006) Cathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin. Mol. Cell. Biol. 26, 4172-4184
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 4172-4184
-
-
Bulynko, Y.A.1
Hsing, L.C.2
Mason, R.W.3
Tremethick, D.J.4
Grigoryev, S.A.5
-
44
-
-
0041689975
-
Insulation of the chicken ß-globin chromosomal domain from a chromatin-condensing protein, MENT
-
Istomina, N. E., Shushanov, S. S., Springhetti, E. M., Karpov, V. L., Krash- eninnikov, I. A., Stevens, K., Zaret, K. S., Singh, P. B., and Grigoryev, S. A. (2003) Insulation of the chicken ß-globin chromosomal domain from a chromatin-condensing protein, MENT. Mol. Cell. Biol. 23, 6455-6468
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6455-6468
-
-
Istomina, N.E.1
Shushanov, S.S.2
Springhetti, E.M.3
Karpov, V.L.4
Krash- Eninnikov, I.A.5
Stevens, K.6
Zaret, K.S.7
Singh, P.B.8
Grigoryev, S.A.9
-
45
-
-
79955460159
-
H3K9 methyltransferase G9a and the related molecule CLP
-
Shinkai, Y., and Tachibana, M. (2011) H3K9 methyltransferase G9a and the related molecule CLP. Genes Dev. 25, 781-788
-
(2011)
Genes Dev.
, vol.25
, pp. 781-788
-
-
Shinkai, Y.1
Tachibana, M.2
-
46
-
-
84861722003
-
Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response
-
Fang, T. C., Schaefer, U., Mecklenbrauker, I., Stienen, A., Dewell, S., Chen, M. S., Rioja, I., Parravicini, V., Prinjha, R. K., Chandwani, R., MacDonald, M. R., Lee, K., Rice, C. M., and Tarakhovsky, A. (2012) Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response. J. Exp. Med. 209, 661-669
-
(2012)
J. Exp. Med.
, vol.209
, pp. 661-669
-
-
Fang, T.C.1
Schaefer, U.2
Mecklenbrauker, I.3
Stienen, A.4
Dewell, S.5
Chen, M.S.6
Rioja, I.7
Parravicini, V.8
Prinjha, R.K.9
Chandwani, R.10
MacDonald, M.R.11
Lee, K.12
Rice, C.M.13
Tarakhovsky, A.14
-
47
-
-
81455154929
-
The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release
-
Hoegen, T., Tremel, N., Klein, M., Angele, B., Wagner, H., Kirschning, C., Pfister, H. W., Fontana, A., Hammerschmidt, S., and Koedel, U. (2011) The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release. J. Immunol. 187, 5440-5451
-
(2011)
J. Immunol.
, vol.187
, pp. 5440-5451
-
-
Hoegen, T.1
Tremel, N.2
Klein, M.3
Angele, B.4
Wagner, H.5
Kirschning, C.6
Pfister, H.W.7
Fontana, A.8
Hammerschmidt, S.9
Koedel, U.10
-
48
-
-
0036434216
-
Reduced cystatin B activity correlates with enhanced cathepsin activity in progressive myoclonus epilepsy
-
Rinne, R., Saukko, P., Järvinen, M., and Lehesjoki, A. E. (2002) Reduced cystatin B activity correlates with enhanced cathepsin activity in progressive myoclonus epilepsy. Ann. Med. 34, 380-385
-
(2002)
Ann. Med.
, vol.34
, pp. 380-385
-
-
Rinne, R.1
Saukko, P.2
Järvinen, M.3
Lehesjoki, A.E.4
-
49
-
-
77956936562
-
P2X(7) receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases
-
Lopez-Castejon, G., Theaker, J., Pelegrin, P., Clifton, A. D., Braddock, M., and Surprenant, A. (2010) P2X(7) receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases. J. Immunol. 185, 2611-2619
-
(2010)
J. Immunol.
, vol.185
, pp. 2611-2619
-
-
Lopez-Castejon, G.1
Theaker, J.2
Pelegrin, P.3
Clifton, A.D.4
Braddock, M.5
Surprenant, A.6
-
50
-
-
58449083290
-
Pyroptosis: Host cell death and inflammation
-
Bergsbaken, T., Fink, S. L., and Cookson, B. T. (2009) Pyroptosis: host cell death and inflammation. Nat. Rev. Microbiol. 7, 99-109
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, pp. 99-109
-
-
Bergsbaken, T.1
Fink, S.L.2
Cookson, B.T.3
-
51
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada, K., Crother, T. R., Karlin, J., Dagvadorj, J., Chiba, N., Chen, S., Ramanujan, V. K., Wolf, A. J., Vergnes, L., Ojcius, D. M., Rentsendorj, A., Vargas, M., Guerrero, C., Wang, Y., Fitzgerald, K. A., Underhill, D. M., Town, T., and Arditi, M. (2012) Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 36, 401-414
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
Ramanujan, V.K.7
Wolf, A.J.8
Vergnes, L.9
Ojcius, D.M.10
Rentsendorj, A.11
Vargas, M.12
Guerrero, C.13
Wang, Y.14
Fitzgerald, K.A.15
Underhill, D.M.16
Town, T.17
Arditi, M.18
-
52
-
-
84863978096
-
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
-
Murakami, T., Ockinger, J., Yu, J., Byles, V., McColl, A., Hofer, A. M., and Horng, T. (2012) Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc. Natl. Acad. Sci. U.S.A. 109, 11282-11287
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 11282-11287
-
-
Murakami, T.1
Ockinger, J.2
Yu, J.3
Byles, V.4
McColl, A.5
Hofer, A.M.6
Horng, T.7
-
53
-
-
65049091899
-
Cystatin B associates with signal transducer and activator of transcription 1 in monocyte-derived and placental macrophages
-
Luciano-Montalvo, C., and Meléndez, L. M. (2009) Cystatin B associates with signal transducer and activator of transcription 1 in monocyte-derived and placental macrophages. Placenta 30, 464-467
-
(2009)
Placenta
, vol.30
, pp. 464-467
-
-
Luciano-Montalvo, C.1
Meléndez, L.M.2
-
54
-
-
84858647958
-
Inhibition of interferon response by cystatin B: Implication in HIV replication of macrophage reservoirs
-
Rivera-Rivera, L., Perez-Laspiur, J., Colón, K., and Meléndez, L. M. (2012) Inhibition of interferon response by cystatin B: implication in HIV replication of macrophage reservoirs. J. Neurovirol. 18, 20-29
-
(2012)
J. Neurovirol.
, vol.18
, pp. 20-29
-
-
Rivera-Rivera, L.1
Perez-Laspiur, J.2
Colón, K.3
Meléndez, L.M.4
-
55
-
-
84896703954
-
Decreased IL-10 expression in stefin B-deficient macrophages is regulated by the MAP kinase and STAT-3 signaling pathways
-
Maher, K., Završnik, J., Jeric-Kokelj, B., Vasiljeva, O., Turk, B., and Kopitar-Jerala, N. (2014) Decreased IL-10 expression in stefin B-deficient macrophages is regulated by the MAP kinase and STAT-3 signaling pathways. FEES Lett. 588, 720-726
-
(2014)
Fees Lett.
, vol.588
, pp. 720-726
-
-
Maher, K.1
Završnik, J.2
Jeric-Kokelj, B.3
Vasiljeva, O.4
Turk, B.5
Kopitar-Jerala, N.6
-
56
-
-
77950362382
-
The inflammasomes
-
Schroder, K., and Tschopp, J. (2010) The inflammasomes. Cell 140, 821-832
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
57
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
Wang, S., Miura, M., Jung, Y. K., Zhu, H., Li, E., and Yuan, J. (1998) Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 92, 501-509
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.K.3
Zhu, H.4
Li, E.5
Yuan, J.6
-
58
-
-
84875483052
-
Mitochondria-targeted drugs enhance Nlrp3 inflammasome-dependent IL-1ß secretion in association with alterations in cellular redox and energy status
-
Jabaut, J., Ather, J. L., Taracanova, A., Poynter, M. E., and Ckless, K. (2013) Mitochondria-targeted drugs enhance Nlrp3 inflammasome-dependent IL-1ß secretion in association with alterations in cellular redox and energy status. Free Radie. Biol. Med. 60, 233-245
-
(2013)
Free Radie. Biol. Med.
, vol.60
, pp. 233-245
-
-
Jabaut, J.1
Ather, J.L.2
Taracanova, A.3
Poynter, M.E.4
Ckless, K.5
-
59
-
-
79955161193
-
Mitochondria: Sovereign of inflammation?
-
Tschopp, J. (2011) Mitochondria: Sovereign of inflammation? Fur. J. Immunol. 41, 1196-1202
-
(2011)
Fur. J. Immunol.
, vol.41
, pp. 1196-1202
-
-
Tschopp, J.1
-
60
-
-
65949112253
-
Cystatin B deficiency sensitizes neurons to oxidative stress in progressive myoclonus epilepsy, EPM1
-
Lehtinen, M. K., Tegelberg, S., Schipper, H., Su, H., Zukor, H., Manninen, O., Kopra, O., Joensuu, T., Hakala, P., Bonni, A., and Lehesjoki, A. E. (2009) Cystatin B deficiency sensitizes neurons to oxidative stress in progressive myoclonus epilepsy, EPM1. J. Neurosci. 29, 5910-5915
-
(2009)
J. Neurosci.
, vol.29
, pp. 5910-5915
-
-
Lehtinen, M.K.1
Tegelberg, S.2
Schipper, H.3
Su, H.4
Zukor, H.5
Manninen, O.6
Kopra, O.7
Joensuu, T.8
Hakala, P.9
Bonni, A.10
Lehesjoki, A.E.11
-
61
-
-
84903639034
-
Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model
-
Butinar, M., Prebanda, M. T., Rajkovič, J., Jerič, B., Stoka, V., Peters, C., Reinheckel, T., Krüger, A., Turk, V., Turk, B., and Vasiljeva, O. (2014) Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model. Oncogene 33, 3392-3400
-
(2014)
Oncogene
, vol.33
, pp. 3392-3400
-
-
Butinar, M.1
Prebanda, M.T.2
Rajkovič, J.3
Jerič, B.4
Stoka, V.5
Peters, C.6
Reinheckel, T.7
Krüger, A.8
Turk, V.9
Turk, B.10
Vasiljeva, O.11
-
62
-
-
2942581328
-
Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain
-
Ricci, J. E., Muñoz-Pinedo, C., Fitzgerald, P., Bailly-Maitre, B., Perkins, G. A., Yadava, N., Scheffler, I. E., Ellisman, M. H., and Green, D. R. (2004) Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell 117, 773-786
-
(2004)
Cell
, vol.117
, pp. 773-786
-
-
Ricci, J.E.1
Muñoz-Pinedo, C.2
Fitzgerald, P.3
Bailly-Maitre, B.4
Perkins, G.A.5
Yadava, N.6
Scheffler, I.E.7
Ellisman, M.H.8
Green, D.R.9
-
63
-
-
0033163393
-
Is NF-κB the sensor of oxidative stress?
-
Li, N., and Karin, M. (1999) Is NF-κB the sensor of oxidative stress? EASES J. 13, 1137-1143
-
(1999)
Eases J.
, vol.13
, pp. 1137-1143
-
-
Li, N.1
Karin, M.2
-
64
-
-
0025739254
-
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1
-
Schreck, R., Rieber, P., and Baeuerle, P. A. (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J. 10, 2247-2258
-
(1991)
Embo J.
, vol.10
, pp. 2247-2258
-
-
Schreck, R.1
Rieber, P.2
Baeuerle, P.A.3
-
65
-
-
0026760583
-
Antioxidants selectively suppress activation of NF-κB by human T-cell leukemia virus type I Tax protein
-
Schreck, R., Grassmann, R., Fleckenstein, B., and Baeuerle, P. A. (1992) Antioxidants selectively suppress activation of NF-κB by human T-cell leukemia virus type I Tax protein.J. Virol. 66, 6288-6293
-
(1992)
J. Virol.
, vol.66
, pp. 6288-6293
-
-
Schreck, R.1
Grassmann, R.2
Fleckenstein, B.3
Baeuerle, P.A.4
-
66
-
-
84655161991
-
-/- mouse model of progressive myoclonus epilepsy, EPM1
-
-/- mouse model of progressive myoclonus epilepsy, EPM1. J. Neuropathol. Exp. Neurol. 71, 40-53
-
(2012)
J. Neuropathol. Exp. Neurol.
, vol.71
, pp. 40-53
-
-
Tegelberg, S.1
Kopra, O.2
Joensuu, T.3
Cooper, J.D.4
Lehesjoki, A.E.5
-
67
-
-
80052220145
-
Expression of innate and adaptive immune mediators in human corneal tissue infected with Aspergillus or Fusarium
-
Karthikeyan, R. S., Leal, S. M., Jr., Prajna, N. V., Dharmalingam, K., Geiser, D. M., Pearlman, E., and Lalitha, P. (2011) Expression of innate and adaptive immune mediators in human corneal tissue infected with Aspergillus or Fusarium. J. Infect. Dis. 204, 942-950
-
(2011)
J. Infect. Dis.
, vol.204
, pp. 942-950
-
-
Karthikeyan, R.S.1
Leal, S.M.2
Prajna, N.V.3
Dharmalingam, K.4
Geiser, D.M.5
Pearlman, E.6
Lalitha, P.7
-
68
-
-
34249809399
-
Expression profiles and function of Toll-like receptors in human corneal epithelia
-
Wu, X. Y., Gao, J. L., and Ren, M. Y. (2007) Expression profiles and function of Toll-like receptors in human corneal epithelia. Chin. Med.J. 120, 893-897
-
(2007)
Chin. Med.J.
, vol.120
, pp. 893-897
-
-
Wu, X.Y.1
Gao, J.L.2
Ren, M.Y.3
|