Early microglial activation precedes neuronal loss in the brain of the Cstb -/- mouse model of progressive myoclonus epilepsy, EPM1

Journal of Neuropathology and Experimental Neurology

Volumn 71, Issue 1, 2012, Pages 40-53

  Tegelberg, Saara ^a   Kopra, Outi ^a   Joensuu, Tarja ^a   Cooper, Jonathan D ^b   Lehesjoki, Anna Elina ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Astrocyte activation; Cerebellum; Cerebral cortex; Cerebrum; Microglia; Myoclonus epilepsy; Neurodegeneration; Posterior thalamic nuclei; Somatosensory cortex

Indexed keywords

CYSTATIN B;

ANIMAL CELL; ARTICLE; ASTROCYTOSIS; BRAIN ATROPHY; BRAIN CORTEX; BRAIN REGION; CELL ACTIVATION; CELL LOSS; DISEASE COURSE; MICROGLIA; MOUSE; MYOCLONUS EPILEPSY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; THALAMOCORTICAL TRACT; THALAMUS NUCLEUS;

ANIMALS; BRAIN; CELL DEATH; CEREBRAL CORTEX; CYSTATIN B; DISEASE MODELS, ANIMAL; MALE; MICE; MICE, KNOCKOUT; MICROGLIA; NEURONS; TIME FACTORS; UNVERRICHT-LUNDBORG SYNDROME;

EID: 84655161991     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0b013e31823e68e1     Document Type: Article

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