메뉴 건너뛰기




Volumn 30, Issue 21, 2014, Pages 3093-3100

Systematic analysis of gene properties influencing organ system phenotypes in mammalian perturbations

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA;

EID: 84911369913     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btu487     Document Type: Article
Times cited : (7)

References (35)
  • 1
    • 70349101984 scopus 로고    scopus 로고
    • Role of the elastin receptor complex (S-Gal/Cath-A/Neu- 1) in skin repair and regeneration
    • Antonicelli, F. et al. (2009) Role of the elastin receptor complex (S-Gal/Cath-A/Neu- 1) in skin repair and regeneration. Wound Repair Regen., 17, 631-638.
    • (2009) Wound Repair Regen. , vol.17 , pp. 631-638
    • Antonicelli, F.1
  • 2
    • 9144232912 scopus 로고    scopus 로고
    • UniProt: The universal protein knowledgebase
    • Apweiler, R. et al. (2004) UniProt: the universal protein knowledgebase. Nucleic Acids Res., 32, D115-D119.
    • (2004) Nucleic Acids Res. , vol.32 , pp. D115-D119
    • Apweiler, R.1
  • 3
    • 35248817286 scopus 로고    scopus 로고
    • Modeling promiscuity based on in vitro safety pharmacology profiling data
    • Azzaoui, K. et al. (2007) Modeling promiscuity based on in vitro safety pharmacology profiling data. ChemMedChem, 2, 874-880.
    • (2007) ChemMedChem , vol.2 , pp. 874-880
    • Azzaoui, K.1
  • 4
    • 78149236787 scopus 로고    scopus 로고
    • DisGeNET: A Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks
    • Bauer-Mehren, A. et al. (2010) DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks. Bioinformatics, 26, 2924-2926.
    • (2010) Bioinformatics , vol.26 , pp. 2924-2926
    • Bauer-Mehren, A.1
  • 5
    • 79958795334 scopus 로고    scopus 로고
    • Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases
    • Bauer-Mehren, A. et al. (2011) Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases. PloS One, 6, e20284.
    • (2011) PloS One , vol.6 , pp. e20284
    • Bauer-Mehren, A.1
  • 6
    • 2442604715 scopus 로고    scopus 로고
    • The genetic association database
    • Becker, K.G. et al. (2004) The genetic association database. Nat. Genet., 36, 431-432.
    • (2004) Nat. Genet. , vol.36 , pp. 431-432
    • Becker, K.G.1
  • 7
    • 58149197592 scopus 로고    scopus 로고
    • The mouse genome database genotypes: Phenotypes
    • Blake, J.A. et al. (2009) The mouse genome database genotypes: phenotypes. Nucleic Acids Res., 37, D712-D719.
    • (2009) Nucleic Acids Res. , vol.37 , pp. D712-D719
    • Blake, J.A.1
  • 8
    • 47249146126 scopus 로고    scopus 로고
    • Drug target identification using side-effect similarity
    • Campillos, M. et al. (2008) Drug target identification using side-effect similarity. Science, 321, 263-266.
    • (2008) Science , vol.321 , pp. 263-266
    • Campillos, M.1
  • 9
    • 34250323499 scopus 로고    scopus 로고
    • The elastin receptor complex transduces signals through the catalytic activity of its Neu-1 subunit
    • Duca, L. et al. (2007) The elastin receptor complex transduces signals through the catalytic activity of its Neu-1 subunit. J. Biol. Chem., 282, 12484-12491.
    • (2007) J. Biol. Chem. , vol.282 , pp. 12484-12491
    • Duca, L.1
  • 10
    • 30344479953 scopus 로고    scopus 로고
    • The benefits of the multi-target approach in drug design and discovery
    • Espinoza-Fonseca, L.M. (2006) The benefits of the multi-target approach in drug design and discovery. Bioorg. Med. Chem., 14, 896-897.
    • (2006) Bioorg. Med. Chem. , vol.14 , pp. 896-897
    • Espinoza-Fonseca, L.M.1
  • 11
    • 84878496035 scopus 로고    scopus 로고
    • From mouse to human: Evolutionary genomics analysis of human orthologs of essential genes
    • Georgi, B. et al. (2013) From mouse to human: evolutionary genomics analysis of human orthologs of essential genes. PLoS Genet., 9, e1003484.
    • (2013) PLoS Genet. , vol.9 , pp. e1003484
    • Georgi, B.1
  • 12
    • 34547140875 scopus 로고    scopus 로고
    • The human disease network
    • Goh, K.-I. et al. (2007) The human disease network. Proc. Natl Acad. Sci. USA, 104, 8685-8690.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 8685-8690
    • Goh, K.-I.1
  • 13
    • 13444266370 scopus 로고    scopus 로고
    • Online Mendelian inheritance in man (OMIM), a knowledgebase of human genes and genetic disorders
    • Hamosh, A. et al. (2005) Online Mendelian inheritance in man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res., 33, D514-D517.
    • (2005) Nucleic Acids Res. , vol.33 , pp. D514-D517
    • Hamosh, A.1
  • 14
    • 42349100173 scopus 로고    scopus 로고
    • The chemical genomic portrait of yeast: Uncovering a phenotype for all genes
    • Hillenmeyer, M.E. et al. (2008) The chemical genomic portrait of yeast: uncovering a phenotype for all genes. Science, 320, 362-365.
    • (2008) Science , vol.320 , pp. 362-365
    • Hillenmeyer, M.E.1
  • 16
    • 15944383403 scopus 로고    scopus 로고
    • Gene-environment interactions in human diseases
    • Hunter, D.J. (2005) Gene-environment interactions in human diseases. Nat. Rev. Genet., 6, 287-298.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 287-298
    • Hunter, D.J.1
  • 17
    • 0035799707 scopus 로고    scopus 로고
    • Lethality and centrality in protein networks
    • Jeong, H. et al. (2001) Lethality and centrality in protein networks. Nature, 411, 41-42.
    • (2001) Nature , vol.411 , pp. 41-42
    • Jeong, H.1
  • 18
    • 33846876695 scopus 로고    scopus 로고
    • Relating protein pharmacology by ligand chemistry
    • Keiser, M.J. et al. (2007) Relating protein pharmacology by ligand chemistry. Nat. Biotechnol., 25, 197-206.
    • (2007) Nat. Biotechnol. , vol.25 , pp. 197-206
    • Keiser, M.J.1
  • 19
    • 84881116194 scopus 로고    scopus 로고
    • Systematic identification of proteins that elicit drug side effects
    • Kuhn, M. et al. (2013) Systematic identification of proteins that elicit drug side effects. Mol. Syst. Biol., 9, 663.
    • (2013) Mol. Syst. Biol. , vol.9 , pp. 663
    • Kuhn, M.1
  • 20
    • 76149120425 scopus 로고    scopus 로고
    • A side effect resource to capture phenotypic effects of drugs
    • Kuhn, M. et al. (2010a) A side effect resource to capture phenotypic effects of drugs. Mol. Syst. Biol., 6, 343.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 343
    • Kuhn, M.1
  • 21
    • 75549087827 scopus 로고    scopus 로고
    • STITCH 2: An interaction network database for small molecules and proteins
    • Kuhn, M. et al. (2010b) STITCH 2: an interaction network database for small molecules and proteins. Nucleic Acids Res., 38, D552-D556.
    • (2010) Nucleic Acids Res. , vol.38 , pp. D552-D556
    • Kuhn, M.1
  • 22
    • 44349173103 scopus 로고    scopus 로고
    • Null mutations in human and mouse orthologs frequently result in different phenotypes
    • Liao, B.-Y. and Zhang, J. (2008) Null mutations in human and mouse orthologs frequently result in different phenotypes. Proc. Natl Acad. Sci. USA, 105, 6987-6992.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 6987-6992
    • Liao, B.-Y.1    Zhang, J.2
  • 23
    • 33745795732 scopus 로고    scopus 로고
    • The comparative toxicogenomics database: A cross-species resource for building chemical-gene interaction networks
    • Mattingly, C.J. et al. (2006) The comparative toxicogenomics database: a cross-species resource for building chemical-gene interaction networks. Toxicol. Sci., 92, 587-595.
    • (2006) Toxicol. Sci. , vol.92 , pp. 587-595
    • Mattingly, C.J.1
  • 24
    • 51349085387 scopus 로고    scopus 로고
    • Data completeness-the Achilles heel of drug-target networks
    • Mestres, J. et al. (2008) Data completeness-the Achilles heel of drug-target networks. Nat. Biotechnol., 26, 983-984.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 983-984
    • Mestres, J.1
  • 25
    • 78650475398 scopus 로고    scopus 로고
    • Phenotypic landscape of a bacterial cell
    • Nichols, R.J. et al. (2011) Phenotypic landscape of a bacterial cell. Cell, 144, 143-156.
    • (2011) Cell , vol.144 , pp. 143-156
    • Nichols, R.J.1
  • 26
    • 77953568669 scopus 로고    scopus 로고
    • Drug hypersensitivity reactions: Pathomechanism and clinical symptoms
    • xv
    • Pichler, W.J. et al. (2010) Drug hypersensitivity reactions: pathomechanism and clinical symptoms. Med. Clin. North Am., 94, 645-664 xv.
    • (2010) Med. Clin. North Am. , vol.94 , pp. 645-664
    • Pichler, W.J.1
  • 27
    • 4644271084 scopus 로고    scopus 로고
    • Magic shotguns versus magic bullets: Selectively non-selective drugs for mood disorders and schizophrenia
    • Roth, B.L. et al. (2004)Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat. Rev. Drug Discov., 3, 353-359.
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 353-359
    • Roth, B.L.1
  • 28
    • 32044442759 scopus 로고    scopus 로고
    • Promoter features related to tissue specificity as measured by Shannon entropy
    • Schug, J. et al. (2005) Promoter features related to tissue specificity as measured by Shannon entropy. Genome Biol., 6, R33.
    • (2005) Genome Biol. , vol.6 , pp. R33
    • Schug, J.1
  • 29
    • 26844450908 scopus 로고    scopus 로고
    • The mammalian phenotype ontology as a tool for annotating, analyzing and comparing phenotypic information
    • Smith, C.L. et al. (2005) The mammalian phenotype ontology as a tool for annotating, analyzing and comparing phenotypic information. Genome Biol., 6, R7.
    • (2005) Genome Biol. , vol.6 , pp. R7
    • Smith, C.L.1
  • 30
    • 11144358198 scopus 로고    scopus 로고
    • A gene atlas of the mouse and human protein-encoding transcriptomes
    • Su, A.I. et al. (2004) A gene atlas of the mouse and human protein-encoding transcriptomes. Proc. Natl Acad. Sci. USA, 101, 6062-6067.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 6062-6067
    • Su, A.I.1
  • 31
    • 84862909349 scopus 로고    scopus 로고
    • Five years of GWAS discovery
    • Visscher, P.M. et al. (2012) Five years of GWAS discovery. Am. J. Hum. Genet., 90, 7-24.
    • (2012) Am. J. Hum. Genet. , vol.90 , pp. 7-24
    • Visscher, P.M.1
  • 32
    • 33846086800 scopus 로고    scopus 로고
    • STRING 7-recent developments in the integration and prediction of protein interactions
    • von Mering, C. et al. (2007) STRING 7-recent developments in the integration and prediction of protein interactions. Nucleic Acids Res., 35, D358-D362.
    • (2007) Nucleic Acids Res. , vol.35 , pp. D358-D362
    • Von Mering, C.1
  • 33
    • 84880763942 scopus 로고    scopus 로고
    • Target essentiality and centrality characterize drug side effects
    • Wang, X. et al. (2013) Target essentiality and centrality characterize drug side effects. PLoS Comput. Biol., 9, e1003119.
    • (2013) PLoS Comput. Biol. , vol.9 , pp. e1003119
    • Wang, X.1
  • 34
    • 84880562927 scopus 로고    scopus 로고
    • Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
    • White, J.K. et al. (2013) Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell, 154, 452-464.
    • (2013) Cell , vol.154 , pp. 452-464
    • White, J.K.1
  • 35
    • 34247622363 scopus 로고    scopus 로고
    • The importance of bottlenecks in protein networks: Correlation with gene essentiality and expression dynamics
    • Yu, H. et al. (2007) The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics. PLoS Comput. Biol., 3, e59.
    • (2007) PLoS Comput. Biol. , vol.3 , pp. e59
    • Yu, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.