Role of the elastin receptor complex (S-Gal/Cath-A/Neu-1) in skin repair and regeneration

Wound Repair and Regeneration

Volumn 17, Issue 5, 2009, Pages 631-638

  Antonicelli, Frank ^b   Bellon, Georges ^b   Lorimier, Sandrine ^b   Hornebeck, William ^a,b  

^a University of Reims Champagne Ardenne ^*  (France)

^b UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; BETA GALACTOSIDASE; CARBOXYPEPTIDASE C; COLLAGEN TYPE 1; ELASTIN; ELASTIN RECEPTOR COMPLEX; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; SIALIDASE; TROPOELASTIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; BURN; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; FIBROBLAST; HUMAN; KERATINOCYTE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REVIEW; TISSUE REGENERATION; TISSUE REPAIR; UPREGULATION; WOUND DRESSING; WOUND HEALING;

CATHEPSIN A; ELASTIN; GALACTOSIDES; HUMANS; NEURAMINIDASE; RECEPTORS, CELL SURFACE; REGENERATION; SKIN; SKIN PHYSIOLOGICAL PHENOMENA; UMBELLIFERONES; WOUND HEALING;

EID: 70349101984     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2009.00525.x     Document Type: Review

References (89)

1. Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med 1999 341 : 738 746.
2. Werner S, Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev 2003 83 : 835 870.
3. Raja D, Sivamani K, Garcia MS, Isseroff RR. Wound re-epithelialization: modulating keratinocyte migration in wound healing. Front Biosci 2007 12 : 2849 2868.
4. Gurtner GC, Werner S, Barrandon Y, Longaker MT. Wound repair and regeneration. Nature 2008 453 : 314 321.
5. Gill SE, Parks WC. Metalloproteinases and their inhibitors: regulators of wound healing. Int J Biochem Cell Biol 2008 40 : 1334 1347.
6. Mirastschijski U, Haaksma CJ, Tomasek JJ, Agren MS. Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin wounds. Exp Cell Res 2004 299 : 465 467.
7. Bullard KM, Lund L, Mudgett JS, Mellin TN, Hunt TK, Murphy B, Ronan J, Werb Z, Banda MJ. Impaired wound contraction in stromelysin-1-deficient mice. Ann Surg 1999 230 : 260 265.
8. Lovvorn HN III., Cheung DT, Nimni ME, Perelman N, Estes JM, Adzick NS. Relative distribution and crosslinking of collagen distinguish fetal from adult sheep wound repair. J Pediatr Surg 1999 34 : 218 223.
9. Kielty CM, Sherratt MJ, Shuttleworth CA. Elastic fibres. J Cell Sci 2002 115 : 2817 2828.
10. Amadeu TP, Braune AS, Porto LC, Desmouliere A, Costa AM. Fibrillin-1 and elastin are differentially expressed in hypertrophic scars and keloids. Wound Repair Regen 2004 12 : 169 174.
11. Clark RA. Cutaneous tissue repair: basic biologic considerations. Int J Am Acad Dermatol 1985 13 : 701 725.
12. Wagenseil JE, Mecham RP. New insights into elastic fiber assembly. Birth Defects Res C Embryo Today 2007 81 : 229 240.
13. Chung MI, Miao M, Stahl RJ, Chan E, Parkinson J, Keeley FW. Sequences and domain structures of mammalian, avian, amphibian and teleost tropoelastins: clues to the evolutionary history of elastins. Matrix Biol 2006 25 : 492 504.
14. Wise SG, Weiss AS. Tropoelastin. Int J Biochem Cell Biol 2008 41 : 494 497.
15. Parks WC, Kolodziej ME, Pierce RA. Phorbol ester-mediated downregulation of tropoelastin expression is controlled by a posttranscriptional mechanism. Biochemistry 1992 31 : 6639 6645.
16. Pierce RA, Moore CH, Arikan MC. Positive transcriptional regulatory element located within exon 1 of elastin gene. Am J Physiol Lung Cell Mol Physiol 2006 291 : L391 9.
17. Ashcroft GS, Kielty CM, Horan MA, Ferguson MW. Age-related changes in the temporal and spatial distributions of fibrillin and elastin mRNAs and proteins in acute cutaneous wounds of healthy humans. J Pathol 1997 183 : 80 9.
18. Frances C, Robert L. Elastin and elastic fibers in normal and pathologic skin. Int J Dermatol 1984 23 : 166 179.
19. Raghunath M, Bächi T, Meuli M, Altermatt S, Gobet R, Bruckner-Tuderman L, Steinman B. Fibrillin and elastin expression in skin regenerating from cultured keratinocyte autografts: morphogenesis of microfibrils begins at the dermo-epidermal junction and precedes elastic fiber formation. J Invest Dermatol 1996 106 : 1090 1095.
20. Carta L, Pereira L, Arteaga-Solis E, Lee-Arteaga SY, Lenart B, Starcher B, Merkel CA, Sukoyan M, Kerkis A, Hazeki N, Keene DR, Sakai LY, Ramirez F. Fibrillins-1 and -2 perform partially overlapping functions during aortic development. J Biol Chem 2006 281 : 8016 8023.
21. Yanagisawa H, Davies EC, Starcher BC, Ouchi T, Yanagisawa M, Richardson A, Olson EN. Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature 2002 425 : 168 171.
22. Antonicelli F, Bellon G, Debelle L, Hornebeck W. Elastin-elastases and inflamm-aging. Curr Top Dev Biol 2007 79 : 99 155.
23. Senior RM, Griffin GL, Mecham RP, Wrenn DS, Prasad KU, Urry DW. Val-Gly-Val-Ala-Pro-Gly. A repeating peptide in elastin, is chemotactic for fibroblasts and monocytes. J Cell Biol 1984 99 : 870 874.
24. Hornebeck W, Tixier JM, Robert L. Inducible adhesion of mesenchymal cells to elastic fibers: elastonectin. Proc Natl Acad Sci USA 1986 83 : 5517 5520.
25. Rodgers UR, Weiss AS. Integrin alpha v beta 3 binds a unique non-RGD site near the C-terminus of human tropoelastin. Biochimie 2004 86 : 173 178.
26. Hinek A, Wrenn DS, Mecham RP, Barondes SH. The elastin receptor: a galactoside-binding protein. Science 1988 239 : 1539 1541.
27. Hinek A, Rabinovitch M, Keeley F, Okamura-Oho Y, Callahan J. The 67-kDa elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of beta-galactosidase. J Clin Invest 1993 91 : 1198 1205.
28. Privitera S, Prody CA, Callahan JW, Hinek A. The 67-kDa enzymatically inactive alternatively spliced variant of beta-galactosidase is identical to the elastin/laminin-binding protein. J Biol Chem 1998 273 : 6319 6326.
29. Hinek A, Pshezhetsky AV, von Itzstein M, Starcher B. Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assembly. J Biol Chem 2006 281 : 3698 3710.
30. Seyrantepe V, Hinek A, Peng J, Fedjaev M, Ernest S, Kadota Y, Canuel M, Itoh K, Morales CR, Lavoie J, Tremblay J, Pshezhetsky AV. Enzymatic activity of lysosomal carboxypeptidase (cathepsin) A is required for proper elastic fiber formation and inactivation of endothelin-1. Circulation 2008 117 : 1973 1981.
31. Wrenn DS, Hinek A, Mecham RP. Kinetics of receptor-mediated binding of tropoelastin to ligament fibroblasts. J Biol Chem 1988 263 : 2280 2284.
32. Caciotti A, Donati MA, Bardelli T, d'Azzo A, Massai G, Luciani L, Zammarchi E, Morrone A. Primary and secondary elastin-binding protein defect leads to impaired elastogenesis in fibroblasts from GM1-gangliosidosis patients. Am J Pathol 2005 167 : 1689 1698.
33. Duca L, Blanchevoye C, Cantarelli B, Ghoneim C, Dedieu S, Delacoux F, Hornebeck W, Hinek A, Martiny L, Debelle L. The elastin receptor complex transduces signals through the catalytic activity of its Neu-1 subunit. J Biol Chem 2007 282 : 12484 12491.
34. Rawlings ND, Morton FR, Kok CY, Kong J, Barrett AJ. MEROPS: the peptidase database. Nucleic Acids Res 2008 36 : D320 5.
35. Hinek A, Rabinovitch M. 67-kDa elastin-binding protein is a protective "companion" of extracellular insoluble elastin and intracellular tropoelastin. J Cell Biol 1994 126 : 563 574.
36. Miao M, Bellingham CM, Stahl RJ, Sitarz EE, Lane CJ, Keeley FW. Sequence and structure determinants for the self-aggregation of recombinant polypeptides modeled after human elastin. J Biol Chem 2003 278 : 48553 48562.
37. Jensen SA, Vrhovski B, Weiss AS. Domain 26 of tropoelastin plays a dominant role in association by coacervation. J Biol Chem 2000 275 : 28449 28454.
38. Toonkool P, Jensen SA, Maxwell AL, Weiss AS. Hydrophobic domains of human tropoelastin interact in a context-dependent manner. J Biol Chem 2001 276 : 44575 44580.
39. Clarke AW, Arnspang EC, Mithieux SM, Korkmaz E, Braet F, Weiss AS. Tropoelastin massively associates during coacervation to form quantized protein spheres. Biochemistry 2006 45 : 9989 9996.
40. Rock MJ, Cain SA, Freeman LJ, Morgan A, Mellody K, Marson A, Shuttleworth CA, Weiss AS, Kielty CM. Molecular basis of elastic fiber formation. Critical interactions and a tropoelastin-fibrillin-1 cross-link. J Biol Chem 2004 279 : 23748 23745.
41. Lemaire R, Bayle J, Mecham RP, Lafyatis R. Microfibril-associated MAGP-2 stimulates elastic fiber assembly. J Biol Chem 2007 282 : 800 808.
42. Cirulis JT, Bellingham CM, Davis EC, Hubmacher D, Reinhardt DP, Mecham RP, Keeley FW. Fibrillins, fibulins, and matrix-associated glycoprotein modulate the kinetics and morphology of in vitro self-assembly of a recombinant elastin-like polypeptide. Biochemistry 2008 47 : 12601 12613.
43. Fogelgren B, Polgar N, Szauter KM, Jfaludi Z, laczko R, Fong KSK, Csiszar K. Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation. J Biol Chem 2005 280 : 24690 24697.
44. Choi J, Bergdahl A, Zheng Q, Starcher B, Yanagisawa H, Davis EC. Analysis of dermal elastic fibers in the absence of fibulin-5 reveals potential roles for fibulin-5 in elastic fiber assembly. Matrix Biol 2009 28 : 211 220.
45. Kozel BA, Rongish BJ, Czirok A, Zach J, Little CD, Davis EC, Knutsen RH, Wagenseil JE, Levy MA, Mecham RP. Elastic fiber formation: a dynamic view of extracellular matrix assembly using timer reporters. J Cell Physiol 2006 207 : 87 96.
46. Debret R, Antonicelli F, Theill A, Hornebeck W, Bernard P, Guenounou M, Le Naour R. Elastin-derived peptides induce a T-helper type 1 polarization of human blood lymphocytes. Arterioscler Thromb Vasc Biol 2005 25 : 1353 1358.
47. Fujimoto N, Tajima S, Ishibashi A. Elastin peptides induce migration and terminal differentiation of cultured keratinocytes via 67 kDa elastin receptor in vitro: 67 kDa elastin receptor is expressed in the keratinocytes eliminating elastic materials in elastosis perforans serpiginosa. J Invest Dermatol 2000 115 : 633 639.
48. Fahem A, Robinet A, Cauchard JH, Duca L, Soula-Rothhut M, Rothhut B, Soria C, Guenounou M, Hornebeck W, Bellon G. Elastokine-mediated up-regulation of MT1-MMP is triggered by nitric oxide in endothelial cells. Int J Biochem Cell Biol 2008 40 : 1581 1596.
49. Robinet A, Millart H, Oszust F, Hornebeck W, Bellon G. Binding of elastin peptides to S-Gal protects the heart against ischemia/reperfusion injury by triggering the RISK pathway. Faseb J 2007 21 : 1968 1967.
50. Kamoun A, Landeau JM, Godeau G, Wallach J, Duchesnay A, Pellat B, Hornebeck W. Growth stimulation of human skin fibroblasts by elastin-derived peptides. Cell Adhes Commun 1995 3 : 273 281.
51. Mochizuki S, Brassart B, Hinek A. Signaling pathways transduced through the elastin receptor facilitate proliferation of arterial smooth muscle cells. J Biol Chem 2002 277 : 44854 44863.
52. Brassart B, Fuchs P, Huet E, Alix AJ, Wallach J, Tamburro AM, Delacoux F, Haye B, Emonard H, Hornebeck W, Debelle L. Conformational dependence of collagenase (matrix metalloproteinase-1) up-regulation by elastin peptides in cultured fibroblasts. J Biol Chem 2001 276 : 5222 5227.
53. Hinek A, Wang Y, Liu K, Mitts TF, Jimenez F. Proteolytic digest derived from bovine Ligamentum nuchae stimulates deposition of new elastin-enriched matrix in cultures and transplants of human dermal fibroblasts. J Dermatol Sci 2005 39 : 155 166.
54. Robinet A, Fahem A, Cauchard JH, Huet E, Vincent L, Lorimier S, Antonicelli F, Soria C, Crepin M, Hornebeck W, Bellon G. Elastin-derived peptides enhance angiogenesis by promoting endothelial cell migration and tubulogenesis through upregulation of MT1-MMP. J Cell Sci 2005 118 : 343 356.
55. Lee PC, Salyapongse AN, Bragdon GA, Shears LL II., Watkins SC, Edington HD, Billiar TR. Impaired wound healing and angiogenesis in eNOS-deficient mice. Am J Physiol 1999 277 : H1600 8.
56. Cozlin A, Barthelemy S, Garnotel R, Antonicelli F, Kaplan H, Hornebeck W, Lorimier S. Elastolysis induces collagenolysis in a gingival lamina propria model. J Dent Res 2006 85 : 745 750.
57. 2+ level in human vascular endothelial cells. Circ Res 1998 82 : 328 336.
58. Daamen WF, Veerkamp JH, van Hest JC, van Kuppevelt TH. Elastin as a biomaterial for tissue engineering. Biomaterials 2007 28 : 4378 4379.
59. de Vries HJ, Middelkoop E, Mekkes JR, Dutrieux RP, Wildevuur CH, Westerhof H. Dermal regeneration in native non-cross-linked collagen sponges with different extracellular matrix molecules. Wound Repair Regen 1994 2 : 37 47.
60. Lamme EN, de Vries HJ, van Veen H, Gabbiani G, Westerhof W, Middelkoop E. Extracellular matrix characterization during healing of full-thickness wounds treated with a collagen/elastin dermal substitute shows improved skin regeneration in pigs. J Histochem Cytochem 1996 44 : 1311 1322.
61. Daamen WF, Nillesen ST, Wismans RG, Reinhardt DP, Hafmans T, Veerkamp JH, van Kuppevelt TH. A biomaterial composed of collagen and solubilized elastin enhances angiogenesis and elastic fiber formation without calcification. Tissue Eng Part A 2008 14 : 349 360.
62. Ryssel H, Gazyakan E, Germann G, Ohlbauer M. The use of MatriDerm in early excision and simultaneous autologous skin grafting in burns - a pilot study. Burns 2008 34 : 93 7.
63. van Houwelingen AH, Weathington NM, Verweij V, Blalock JE, Nijkamp FP, Folkerts G. Induction of lung emphysema is prevented by l-arginine-threonine- arginine. FASEB J 2008 22 : 3403 3408.
64. del Mercato LL, Maruccio G, Pompa PP, Bochicchio B, Tamburro AM, Cingolani R, Rinaldi R. Amyloid-like fibrils in elastin-related polypeptides: structural characterization and elastic properties. Biomacromolecules 2008 9 : 796 803.
65. Hashimoto T, Suzuki Y, Tanihara M, Kakimaru Y, Suzuki K. Development of alginate wound dressings linked with hybrid peptides derived from laminin and elastin. Biomaterials 2004 25 : 1407 1414.
66. Kaufmann D, Fiedler A, Junger A, Auernheimer J, Kessler H, Weberskirch R. Chemical conjugation of linear and cyclic RGD moieties to a recombinant elastin-mimetic polypeptide - a versatile approach towards bioactive protein hydrogels. Macromol Biosci 2008 8 : 577 588.
67. Annabi N, Mithieux SM, Weiss AS, Dehghani F. The fabrication of elastin-based hydrogels using high pressure CO(2). Biomaterials 2008. Epub ahead of print.
68. Mithieux SM, Tu Y, Korkmaz E, Braet F, Weiss AS. In situ polymerization of tropoelastin in the absence of chemical cross-linking. Biomaterials 2009 30 : 431 435.
69. Davidson JM, Giro M. Healing slack skin. J Invest Dermatol 2006 126 : 2563 2564.
70. Boyd CD, Kniep AC, Pierce RA, Deak SB, Karboski C, Miller DC, Parker MI, Machenzie JW, Rosenbloom J, Scott GE. Increased elastin mRNA levels associated with surgically induced intimal injury. Connect Tissue Res 1988 18 : 65 78.
71. Belknap JK, Grieshaber NA, Schwartz PE, Orton E, Reidy MA, Majack RA. Tropoelastin gene expression in individual vascular smooth muscle cells. Relationship to DNA synthesis during vascular development and after arterial injury. Circ Res 1996 78 : 388 394.
72. Jacob MP. Extracellular matrix remodelling and matrix metalloproteinases in the vascular wall during aging and in pathological conditions. Biomedicine et Pharmacotherapy 2003 57 : 195 202.
73. Shifren A, Mecham RP. The stumbling block in lung repair of emphysema: elastic fiber assembly. Proc Am Thorac Soc 2006 3 : 428 433.
74. Postma S, Timens W. Remodeling in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006 3 : 434 439.
75. Davidson JM. Biochemistry and turnover of lung interstitium. Eur Respir J 1990 3 : 1048 1063.
76. Lutolf MP, Hubbell JA. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol 2005 23 : 47 55.
77. Lee J, Macosko CW, Urry DW. Elastomeric polypentapeptides cross-linked into matrixes and fibers. Biomacromolecules 2001 2 : 170 179. (Pubitemid 32707488)
78. Urry DW, Pattanaik A, Xu J, Woods TC, McPherson DT, Parker TM. Elastic protein-based polymers in soft tissue augmentation and generation. J Biomater Sci Polym Ed 1998 9 : 1015 1048.
79. Chilkoti A, Christensen T, MacKay J.A. Stimulus responsive elastin biopolymers: applications in medicine and biotechnology. Curr Opin Chem Biol 2006 10 : 652 657.
80. Hornebeck W, Partridge SM. Conformational changes in fibrous elastin due to calcium ions. Eur J Biochem 1975 51 : 73 8.
81. Lee JS, Basalyga DM, Simionescu A, Isenburg JC, Simionescu DT, Vyavahare NR. Elastin calcification in the rat subdermal model is accompanied by up-regulation of degradative and osteogenic cellular responses. Am J Pathol 2006 168 : 490 498.
82. Hollinger JO, Schmitz JP, Yaskovich R, Long MM, Prasad KU, Urry DW. A synthetic polypentapeptide of elastin for initiating calcification. Calcif Tissue Int 1988 42 : 231 236.
83. Chaussain Miller C, Septier D, Bonnefoix M, Lecolle S, Lebreton-Decoster C, Coulomb B, Pellat B, Godeau G. Human dermal and gingival fibroblasts in a three-dimensional culture: a comparative study on matrix remodeling. Clin Oral Investig 2002 6 : 39 50.
84. Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 2002 3 : 349 363.
85. Fioretti F, Lebreton-DeCoster C, Gueniche F, Yousfi M, Humbert P, Godeau G, Senni K, Desmoulière A, Coulomb B. Human bone marrow-derived cells: an attractive source to populate dermal substitutes. Wound Repair Regen 2008 16 : 87 94.
86. Ashcroft GS, Horan MA, Ferguson M.W. Aging is associated with reduced deposition of specific extracellular matrix components, an upregulation of angiogenesis, and an altered inflammatory response in a murine incisional wound healing model. J Invest Dermatol 1997 108 : 430 437.
87. Mizuno T, Mickle DA, Kiani CG, Li RK. Overexpression of elastin fragments in infarcted myocardium attenuates scar expansion and heart dysfunction. Am J Physiol Heart Circ Physiol 2005 288 : H2819 27.
88. Houghton AM, Quintero PA, Perkins DL, Kobayashi DK, Kelley DG, Marconcini LA, Mecham RP, Senior RM, Shapiro SD. Elastin fragments drive disease progression in a murine model of emphysema. J Clin Invest 2006 116 : 753 759.
89. Nackman GB, Rarkowski FJ, Halpern VJ, Gaetz HP, Tilson MD. Elasting degradation products induce adventitial angiogenesis in the Anidjar/Dobrin rat aneurysm model. Surgery 1997 122 : 39 404.