-
1
-
-
20244387299
-
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.
-
Adolfsson, J. et al. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 121, 295-306 (2005).
-
(2005)
Cell
, vol.121
, pp. 295-306
-
-
Adolfsson, J.1
-
2
-
-
77951002652
-
Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.
-
Mansson, R. et al. Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity. Blood 115, 2601-2609 (2010).
-
(2010)
Blood
, vol.115
, pp. 2601-2609
-
-
Mansson, R.1
-
3
-
-
35348875823
-
The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways.
-
Ishikawa, F. et al. The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways. Blood 110, 3591-3660 (2007).
-
(2007)
Blood
, vol.110
, pp. 3591-3660
-
-
Ishikawa, F.1
-
4
-
-
34248199004
-
Bifurcation dynamics in lineage-commitment in bipotent progenitor cells
-
Huang, S., Guo, Y.P., May, G. and Enver, T. Bifurcation dynamics in lineage-commitment in bipotent progenitor cells. Dev. Biol. 305, 695-713 (2007).
-
(2007)
Dev. Biol
, vol.305
, pp. 695-713
-
-
Huang, S.1
Guo, Y.P.2
May, G.3
Enver, T.4
-
5
-
-
34247092922
-
Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors.
-
Månsson, R. et al. Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors. Immunity 26, 407-419 (2007).
-
(2007)
Immunity
, vol.26
, pp. 407-419
-
-
Månsson, R.1
-
6
-
-
38449102306
-
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
-
Pongubala, J.M. et al. Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat. Immunol. 9, 203-215 (2008).
-
(2008)
Nat. Immunol
, vol.9
, pp. 203-215
-
-
Pongubala, J.M.1
-
7
-
-
18244386710
-
IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF
-
Kikuchi, K., Lai, A.Y., Hsu, C.L. and Kondo, M. IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF. J. Exp. Med. 201, 1197-1203 (2005).
-
(2005)
J. Exp. Med
, vol.201
, pp. 1197-1203
-
-
Kikuchi, K.1
Lai, A.Y.2
Hsu, C.L.3
Kondo, M.4
-
8
-
-
33846141460
-
Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5
-
Roessler, S. et al. Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5. Mol. Cell. Biol. 27, 579-594 (2007).
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 579-594
-
-
Roessler, S.1
-
9
-
-
51549083884
-
EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors.
-
Zandi, S. et al. EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors. J. Immunol. 181, 3364-3372 (2008).
-
(2008)
J. Immunol
, vol.181
, pp. 3364-3372
-
-
Zandi, S.1
-
10
-
-
77953763449
-
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
-
Lin,, Y.C. et al. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat. Immunol. 11, 635-643 (2010).
-
(2010)
Nat. Immunol
, vol.11
, pp. 635-643
-
-
Lin, Y.C.1
-
11
-
-
0033533891
-
Commitment to the B-lymphoid lineage depends on the transcription factor Pax5.
-
Nutt, S.L., Heavey, B., Rolink, A.G. and Busslinger, M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 401, 556-562 (1999).
-
(1999)
Nature
, vol.401
, pp. 556-562
-
-
Nutt, S.L.1
Heavey, B.2
Rolink, A.G.3
Busslinger, M.4
-
12
-
-
84866839947
-
Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo
-
Zandi, S. et al. Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo. Proc. Natl. Acad. Sci. USA 109, 15871-15876 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 15871-15876
-
-
Zandi, S.1
-
13
-
-
2542455620
-
Stepwise reprogramming of B cells into macrophages.
-
Xie, H., Ye, M., Feng, R. and Graf, T. Stepwise reprogramming of B cells into macrophages. Cell 117, 663-676 (2004).
-
(2004)
Cell
, vol.117
, pp. 663-676
-
-
Xie, H.1
Ye, M.2
Feng, R.3
Graf, T.4
-
14
-
-
80054746874
-
CCAAT/enhancer binding protein α (C/EBPα)-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation
-
Di Tullio, A. et al. CCAAT/enhancer binding protein α (C/EBPα)-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation. Proc. Natl. Acad. Sci. USA 108, 17016-17021 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 17016-17021
-
-
Di Tullio, A.1
-
15
-
-
0029805130
-
Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site
-
Oyake, T. et al. Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol. Cell. Biol. 16, 6083-6095 (1996).
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 6083-6095
-
-
Oyake, T.1
-
16
-
-
2942537762
-
The transcriptional programme of antibody class switching involves the repressor Bach2.
-
Muto, A. et al. The transcriptional programme of antibody class switching involves the repressor Bach2. Nature 429, 566-571 (2004).
-
(2004)
Nature
, vol.429
, pp. 566-571
-
-
Muto, A.1
-
17
-
-
78649688039
-
Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch.
-
Muto, A. et al. Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch. EMBO J. 29, 4048-4061 (2010).
-
(2010)
EMBO J
, vol.29
, pp. 4048-4061
-
-
Muto, A.1
-
18
-
-
84882281048
-
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint
-
Swaminathan, S. et al. BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint. Nat. Med. 19, 1014-1022 (2013).
-
(2013)
Nat. Med
, vol.19
, pp. 1014-1022
-
-
Swaminathan, S.1
-
19
-
-
84879685794
-
BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis.
-
Roychoudhuri, R. et al. BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis. Nature 498, 506-510 (2013).
-
(2013)
Nature
, vol.498
, pp. 506-510
-
-
Roychoudhuri, R.1
-
20
-
-
84879537754
-
Bach2 maintains T cells in a naive state by suppressing effector memory-related genes
-
Tsukumo, S. et al. Bach2 maintains T cells in a naive state by suppressing effector memory-related genes. Proc. Natl. Acad. Sci. USA 110, 10735-10740 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 10735-10740
-
-
Tsukumo, S.1
-
21
-
-
84886851330
-
Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function
-
Nakamura, A. et al. Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function. J. Exp. Med. 210, 2191-2204 (2013).
-
(2013)
J. Exp. Med
, vol.210
, pp. 2191-2204
-
-
Nakamura, A.1
-
22
-
-
79958833141
-
The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells
-
McManus, S. et al. The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells. EMBO J. 30, 2388-2404 (2011).
-
(2011)
EMBO J
, vol.30
, pp. 2388-2404
-
-
McManus, S.1
-
23
-
-
0028048369
-
Generation of lymphohematopoietic cells from embryonic stem cells in culture.
-
Nakano, T., Kodama, H. and Honjo, T. Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science 265, 1098-1101 (1994).
-
(1994)
Science
, vol.265
, pp. 1098-1101
-
-
Nakano, T.1
Kodama, H.2
Honjo, T.3
-
24
-
-
0025248588
-
Clonal growth of murine pre-B colony-forming cells and their targeted infection by a retroviral vector: Dependence on interleukin-7.
-
Williams, D.E., Namen, A.E., Mochizuki, D.Y. and Overell, R.W. Clonal growth of murine pre-B colony-forming cells and their targeted infection by a retroviral vector: dependence on interleukin-7. Blood 75, 1132-1138 (1990).
-
(1990)
Blood
, vol.75
, pp. 1132-1138
-
-
Williams, D.E.1
Namen, A.E.2
Mochizuki, D.Y.3
Overell, R.W.4
-
25
-
-
17144422917
-
Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors
-
Dias, S., Silva, H. Jr., Cumano, A. and Vieira, P. Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors. J. Exp. Med. 201, 971-979 (2005).
-
(2005)
J. Exp. Med
, vol.201
, pp. 971-979
-
-
Dias, S.1
Silva, H.2
Cumano, A.3
Vieira, P.4
-
26
-
-
50849143861
-
B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells.
-
Mansson, R. et al. B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells. Blood 112, 1048-1055 (2008).
-
(2008)
Blood
, vol.112
, pp. 1048-1055
-
-
Mansson, R.1
-
27
-
-
77954321988
-
An essential developmental checkpoint for production of the T cell lineage.
-
Ikawa, T. et al. An essential developmental checkpoint for production of the T cell lineage. Science 329, 93-96 (2010).
-
(2010)
Science
, vol.329
, pp. 93-96
-
-
Ikawa, T.1
-
28
-
-
0030956715
-
CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation.
-
Matsumoto, A. et al. CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. Blood 89, 3148-3154 (1997).
-
(1997)
Blood
, vol.89
, pp. 3148-3154
-
-
Matsumoto, A.1
-
29
-
-
70350093398
-
Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development.
-
Inlay, M.A. et al. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 23, 2376-2381 (2009).
-
(2009)
Genes Dev
, vol.23
, pp. 2376-2381
-
-
Inlay, M.A.1
-
30
-
-
48749094942
-
E2A proteins promote development of lymphoid-primed multipotent progenitors.
-
Dias, S. et al. E2A proteins promote development of lymphoid-primed multipotent progenitors. Immunity 29, 217-227 (2008).
-
(2008)
Immunity
, vol.29
, pp. 217-227
-
-
Dias, S.1
-
31
-
-
18644378321
-
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene.
-
Sun, J. et al. Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene. EMBO J. 21, 5216-5224 (2002).
-
(2002)
EMBO J
, vol.21
, pp. 5216-5224
-
-
Sun, J.1
-
32
-
-
24744442149
-
Inhibition of EBF function by active Notch signaling reveals a novel regulatory pathway in early B-cell development.
-
Smith, E.M. et al. Inhibition of EBF function by active Notch signaling reveals a novel regulatory pathway in early B-cell development. Blood 106, 1995-2001 (2005).
-
(2005)
Blood
, vol.106
, pp. 1995-2001
-
-
Smith, E.M.1
-
33
-
-
0034717335
-
Regulation of B lymphocyte and macrophage development by graded expression of PU.1.
-
DeKoter, R.P. and Singh, H. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288, 1439-1441 (2000).
-
(2000)
Science
, vol.288
, pp. 1439-1441
-
-
Dekoter, R.P.1
Singh, H.2
-
34
-
-
42049089318
-
Adult T-cell progenitors retain myeloid potential.
-
Wada, H. et al. Adult T-cell progenitors retain myeloid potential. Nature 452, 768-772 (2008).
-
(2008)
Nature
, vol.452
, pp. 768-772
-
-
Wada, H.1
-
35
-
-
77954329976
-
An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b.
-
Li, L., Leid, M. and Rothenberg, E.V. An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b. Science 329, 89-93 (2010).
-
(2010)
Science
, vol.329
, pp. 89-93
-
-
Li, L.1
Leid, M.2
Rothenberg, E.V.3
-
36
-
-
58249104981
-
Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis.
-
Kohyama, M. et al. Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis. Nature 457, 318-321 (2009).
-
(2009)
Nature
, vol.457
, pp. 318-321
-
-
Kohyama, M.1
-
37
-
-
55249115644
-
Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling
-
Zhu, X. et al. Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling. Eur. J. Immunol. 38, 2587-2599 (2008).
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 2587-2599
-
-
Zhu, X.1
-
38
-
-
0242416539
-
Noise in eukaryotic gene expression.
-
Blake, W.J., M K, A., Cantor, C.R. and Collins, J.J. Noise in eukaryotic gene expression. Nature 422, 633-637 (2003).
-
(2003)
Nature
, vol.422
, pp. 633-637
-
-
Blake, W.J.1
Cantor, C.R.2
Collins, J.J.3
-
39
-
-
84859641038
-
Using gene expression noise to understand gene regulation.
-
Munsky, B., Neuert, G. and van, O.A. Using gene expression noise to understand gene regulation. Science 336, 183-187 (2012).
-
(2012)
Science
, vol.336
, pp. 183-187
-
-
Munsky, B.1
Neuert, G.2
Van, O.A.3
-
40
-
-
79956292375
-
Heme regulates B cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2.
-
Watanabe-Matsui, M. et al. Heme regulates B cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2. Blood 117, 5438-5448 (2011).
-
(2011)
Blood
, vol.117
, pp. 5438-5448
-
-
Watanabe-Matsui, M.1
-
41
-
-
84900515792
-
Wearing red for signaling: The heme-bach axis in heme metabolism, oxidative stress response and iron immunology
-
Igarashi, K. and Watanabe-Matsui, M. Wearing red for signaling: the heme-bach axis in heme metabolism, oxidative stress response and iron immunology. Tohoku J. Exp. Med. 232, 229-253 (2014).
-
(2014)
Tohoku J. Exp. Med
, vol.232
, pp. 229-253
-
-
Igarashi, K.1
Watanabe-Matsui, M.2
-
42
-
-
77951912210
-
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
-
Guo, G. et al. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev. Cell 18, 675-685 (2010).
-
(2010)
Dev. Cell
, vol.18
, pp. 675-685
-
-
Guo, G.1
-
43
-
-
0037036377
-
Activation of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with promyelocytic leukemia nuclear bodies
-
Muto, A. et al. Activation of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with promyelocytic leukemia nuclear bodies. J. Biol. Chem. 277, 20724-20733 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 20724-20733
-
-
Muto, A.1
-
44
-
-
81255154496
-
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2
-
Mandal, M. et al. Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2. Nat. Immunol. 12, 1212-1220 (2011).
-
(2011)
Nat. Immunol
, vol.12
, pp. 1212-1220
-
-
Mandal, M.1
-
45
-
-
84857195761
-
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation
-
Ochiai, K. et al. A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat. Immunol. 13, 300-307 (2012).
-
(2012)
Nat. Immunol
, vol.13
, pp. 300-307
-
-
Ochiai, K.1
-
46
-
-
0029080316
-
Conditional expression of the ubiquitous transcription factor MafK induces erythroleukemia cell differentiation
-
Igarashi, K., Itoh, K., Hayashi, N., Nishizawa, M. and Yamamoto, M Conditional expression of the ubiquitous transcription factor MafK induces erythroleukemia cell differentiation. Proc. Natl. Acad. Sci. USA 92, 7445-7449 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7445-7449
-
-
Igarashi, K.1
Itoh, K.2
Hayashi, N.3
Nishizawa, M.4
Yamamoto, M.5
|