Sortase A: An ideal target for anti-virulence drug development

Microbial Pathogenesis

Volumn 77, Issue , 2014, Pages 105-112

  Cascioferro, Stella ^a   Totsika, Makrina ^b   Schillaci, Domenico ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Antimicrobial resistance; Antivirulence drugs; Gram positive pathogens; Sortase A; Sortase A inhibitors

Indexed keywords

3 (2,5 DIMETHOXYPHENYL) 2 (4 METHOXYPHENYL)ACRYLONITRILE; BERBERINE; BETA SITOSTEROL 3 O GLUCOPYRANOSIDE; BROMODEOXYTOPSENTIN; CURCUMIN; DEOXYTOPSENTIN; DISCORHABDIN Z; ENZYME INHIBITOR; HALISULFATE 1; ISOAAPTAMIN; KURARINOL; METHYL(2E) 2,3 BIS(4 METHOXYPHENYL)PROP 2 ENOATE; MORIN; MYRICETIN; NATURAL PRODUCT; PSAMMAPLIN A1; QUERCETIN; SITOSTEROL DERIVATIVE; SORTASE; SORTASE A; UNCLASSIFIED DRUG; AMINOACYLTRANSFERASE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; CYSTEINE PROTEINASE; VIRULENCE FACTOR;

ANTIVIRULENCE ACTIVITY; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BIOFILM; CELL MEMBRANE; DISEASE SEVERITY; DRUG ACTIVITY; DRUG SYNTHESIS; DRUG TARGETING; HIGH THROUGHPUT SCREENING; HOST RESISTANCE; HUMAN; IC50; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PATHOGENESIS; REVIEW; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; ANTAGONISTS AND INHIBITORS; DRUG DEVELOPMENT; DRUG EFFECTS; ENZYMOLOGY; GRAM POSITIVE BACTERIUM; ISOLATION AND PURIFICATION; METABOLISM; PROCEDURES; VIRULENCE;

AMINOACYLTRANSFERASES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CYSTEINE ENDOPEPTIDASES; DRUG DISCOVERY; GRAM-POSITIVE BACTERIA; VIRULENCE; VIRULENCE FACTORS;

EID: 84910680420     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2014.10.007     Document Type: Review

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