Crystal Structure of streptococcus pyogenes Sortase A: Implications for sortase mechanism

Journal of Biological Chemistry

Volumn 284, Issue 11, 2009, Pages 6924-6933

  Race, Paul R ^a   Bentley, Matthew L ^b   Melvin, Jeff A ^b   Crow, Allister ^c   Hughes, Richard K ^c   Smith, Wendy D ^a   Sessions, Richard B ^d   Kehoe, Michael A ^a   McCafferty, Dewey G ^b   Banfield, Mark J ^a,c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b DUKE UNIVERSITY   (United States)

^c JOHN INNES CENTRE   (United Kingdom)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ALKYLATING REAGENTS; ANTI-MICROBIAL AGENT; BACTERIAL CELL SURFACE; BACTERIAL CELLS; BACTERIAL PATHOGENS; CATALYTIC MECHANISMS; CATALYTIC RESIDUE; GRAM-POSITIVE PATHOGENS; HUMAN PATHOGENS; IN-VITRO; INHIBITOR DESIGN; KINETIC ANALYSIS; PEPTIDOGLYCAN; SECRETED PROTEIN; SORTASE; STREPTOCOCCUS PYOGENES; SUBSTRATE RECOGNITION; SULFENIC ACIDS; SURFACE PROTEINS;

BACTERIOLOGY; CATALYTIC OXIDATION; CELL MEMBRANES; PATHOGENS; PROTEINS; QUANTUM CHEMISTRY;

CRYSTAL STRUCTURE;

CYSTEINE; SORTASE; SORTASE A; SULFENIC ACID DERIVATIVE; UNCLASSIFIED DRUG; AMINOACYLTRANSFERASE; BACTERIAL PROTEIN; CYSTEINE PROTEINASE;

ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME MODIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; HOUSEKEEPING GENE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; STREPTOCOCCUS PYOGENES; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; KINETICS; OXIDATION REDUCTION REACTION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOCOCCUS PYOGENES;

AMINOACYLTRANSFERASES; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYSTEINE ENDOPEPTIDASES; KINETICS; OXIDATION-REDUCTION; PROTEIN STRUCTURE, TERTIARY; STREPTOCOCCUS PYOGENES; SULFENIC ACIDS;

EID: 65449140986     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805406200     Document Type: Article

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