Induction of Pi form of glutathione S -transferase by carnosic acid is mediated through PI3K/Akt/NF-κB pathway and protects against neurotoxicity

Chemical Research in Toxicology

Volumn 27, Issue 11, 2014, Pages 1958-1966

  Lin, Chia Yuan ^a   Chen, Jing Hsien ^b,c   Fu, Ru Huei ^a,d   Tsai, Chia Wen ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CARNOSIC ACID; CASPASE 3; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OXIDOPAMINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SYNAPTOTAGMIN I; ABIETANE DERIVATIVE; GLUTATHIONE TRANSFERASE P1; NEUROPROTECTIVE AGENT; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNOBLOTTING; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; ENZYME INDUCTION; ENZYMOLOGY; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; NEUROTOXICITY SYNDROMES; TUMOR CELL LINE; WESTERN BLOTTING; WISTAR RAT;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME INDUCTION; GLUTATHIONE S-TRANSFERASE PI; HUMANS; MALE; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; NF-KAPPA B; OXIDOPAMINE; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; RATS, WISTAR; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84910676294     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx5003063     Document Type: Article

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