Iron increases APP translation and amyloid-beta production in the retina

Experimental Eye Research

Volumn 129, Issue , 2014, Pages 31-37

  Guo, Lucie Y ^a   Alekseev, Oleg ^a,b   Li, Yafeng ^a   Song, Ying ^a   Dunaief, Joshua L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Aceruloplasminemia; Age related macular degeneration; Amyloid precursor protein; Amyloid beta; Iron

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; DEFERIPRONE; FERRIC AMMONIUM CITRATE; IRON; ROSAPROSTOL; APP PROTEIN, HUMAN; MESSENGER RNA;

ACERULOPLASMINEMIA; ADULT; AGE RELATED MACULAR DEGENERATION; ARTICLE; AUTOSOMAL DISORDER; CASE REPORT; DRUSEN; EPITHELIUM CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IRON OVERLOAD; MALE; MIDDLE AGED; PIGMENT EPITHELIUM; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN SECRETION; TISSUE SECTION; UPREGULATION; BIOSYNTHESIS; CELL CULTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; MACULAR DEGENERATION; METABOLISM; PATHOLOGY; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AMYLOID BETA-PROTEIN PRECURSOR; BLOTTING, WESTERN; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; IRON; MACULAR DEGENERATION; MALE; MIDDLE AGED; PROTEIN BIOSYNTHESIS; REAL-TIME POLYMERASE CHAIN REACTION; RETINAL PIGMENT EPITHELIUM; RNA, MESSENGER;

EID: 84910071896     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2014.10.012     Document Type: Article

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