Long circulating self-assembled nanoparticles from cholesterol-containing brush-like block copolymers for improved drug delivery to tumors

Biomacromolecules

Volumn 15, Issue 11, 2014, Pages 4363-4375

  Tran, Thanh Huyen ^a   Nguyen, Chi Thanh ^a   Gonzalez Fajardo, Laura ^a   Hargrove, Derek ^a   Song, Donghui ^a   Deshmukh, Prashant ^a   Mahajan, Lalit ^a   Ndaya, Dennis ^a   Lai, Laijun ^a   Kasi, Rajeswari M ^a   Lu, Xiuling ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOCK COPOLYMERS; CHOLESTEROL; DRUG DELIVERY; ETHYLENE; ETHYLENE GLYCOL; NANOPARTICLES; STRESS ANALYSIS;

AMPHIPHILIC BRUSHES; CERVICAL CANCER CELLS; CIRCULATION TIME; HIGH DRUG LOADINGS; IN-VIVO IMAGING; LONG CIRCULATING; SELF ASSEMBLED NANOPARTICLES; TISSUE DISTRIBUTIONS;

TUMORS;

ALANINE AMINOTRANSFERASE; AMPHOPHILE; CHOLESTEROL; COPOLYMER; DOXORUBICIN; IDARUBICIN; MACROGOL; NANOPARTICLE; POLYNORBENE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; POLYMER;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DOSE REDUCTION; DRUG STABILITY; DRUG TISSUE LEVEL; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER TOXICITY; MALE; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; SCID MOUSE; SINGLE DRUG DOSE; STEADY STATE; SUSTAINED DRUG RELEASE; TISSUE DISTRIBUTION; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DRUG SCREENING; NUDE MOUSE; PROCEDURES; RANDOMIZATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CHOLESTEROL; DRUG DELIVERY SYSTEMS; HELA CELLS; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICE, SCID; NANOPARTICLES; POLYMERS; RANDOM ALLOCATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84910047113     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm5013822     Document Type: Article

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