HPLC quantification of doxorubicin in plasma and tissues of rats treated with doxorubicin loaded poly(alkylcyanoacrylate) nanoparticles

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 887-888, Issue , 2012, Pages 128-132

  Alhareth, Khairallah ^a,b,c   Vauthier, Christine ^a,b   Gueutin, Claire ^a,b   Ponchel, Gilles ^a,b   Moussa, Fathi ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b CNRS   (France)

^c IUST   (Syrian Arab Republic)

Author keywords

Doxorubicin; Doxorubicinol; Doxorubicinon; Idarubicin; Poly(alkylcyanoacrylate) nanoparticles

Indexed keywords

ALKYLCYANOACRYLATE; DOXORUBICIN; DOXORUBICINOL; DOXORUBICINON; IDARUBICIN;

CHROMATOGRAPHIC ANALYSIS; DRUG DELIVERY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOLOGY; PHARMACOKINETICS; RATS; TISSUE;

NANOPARTICLES;

ADRIAMYCINONE; CYANOACRYLATE DERIVATIVE; DOXORUBICIN; DOXORUBICINOL; IDARUBICIN; NANOPARTICLE; POLY(ALKYLCYANOACRYLATE); UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; DRUG ISOLATION; DRUG LIVER LEVEL; DRUG TISSUE LEVEL; EMULSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SINGLE DRUG DOSE; SPLEEN;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYANOACRYLATES; DOXORUBICIN; IDARUBICIN; LIMIT OF DETECTION; LIVER; MALE; MYOCARDIUM; NANOPARTICLES; POLYMERS; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SPLEEN; TISSUE DISTRIBUTION;

RATTUS;

EID: 84857140762     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.01.025     Document Type: Article

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