Biodistribution and bioimaging studies of hybrid paclitaxel nanocrystals: Lessons learned of the EPR effect and image-guided drug delivery

Journal of Controlled Release

Volumn 172, Issue 1, 2013, Pages 12-21

  Hollis, Christin P ^a   Weiss, Heidi L ^b   Leggas, Markos ^a   Evers, B Mark ^c   Gemeinhart, Richard A ^d   Li, Tonglei ^e  

^a University of Kentucky   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^e PURDUE UNIVERSITY   (United States)

Author keywords

Biodistribution; Chemotherapy; EPR; Nanocrystals; Paclitaxel; Theranostics

Indexed keywords

ANTI-TUMOR ACTIVITIES; BIODISTRIBUTIONS; ENHANCED PERMEABILITY AND RETENTION EFFECTS; FLUORESCENT INTENSITY; INTRAVENOUS ADMINISTRATION; PACLITAXEL; SCINTILLATION COUNTING; THERANOSTICS;

ANIMALS; CHEMOTHERAPY; DIAGNOSIS; DRUG DELIVERY; DRUG DOSAGE; FLUORESCENCE; INFRARED DEVICES; OPTICAL IMAGE STORAGE; PARAMAGNETIC RESONANCE; PHARMACOKINETICS; TOXICITY; TRITIUM; TUMORS;

NANOCRYSTALS;

FLUORESCENT DYE; NANOCRYSTAL; PACLITAXEL; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; COLON CANCER; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG RETENTION; EX VIVO STUDY; FEMALE; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; HYBRID; INFRARED RADIATION; ISOTOPE LABELING; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; SCINTILLATION COUNTING; SOLUBILIZATION; SURVIVAL; SURVIVAL TIME; TISSUE DISTRIBUTION; TUMOR XENOGRAFT;

BIODISTRIBUTION; CHEMOTHERAPY; EPR; NANOCRYSTALS; PACLITAXEL; THERANOSTICS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; COLONIC NEOPLASMS; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; MICE; MICE, NUDE; NANOPARTICLES; OPTICAL IMAGING; PACLITAXEL; PERMEABILITY; TISSUE DISTRIBUTION;

EID: 84883492467     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.06.039     Document Type: Article

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