Molecular nanoworm with PCL core and PEO shell as a non-spherical carrier for drug delivery

Macromolecular Rapid Communications

Volumn 33, Issue 16, 2012, Pages 1351-1355

  Zhao, Peng ^a   Liu, Lixin ^b   Feng, Xiaoqin ^b   Wang, Chun ^c   Shuai, Xintao ^d   Chen, Yongming ^a  

^a INSTITUTE OF CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c University of Minnesota   (United States)

^d SUN YAT SEN UNIVERSITY   (China)

Author keywords

controlled polymerization; drug delivery systems; graft copolymers; polymer brushes

Indexed keywords

ALKYNYLS; ANTICANCER DRUG; AVERAGE LENGTH; CAPROLACTONE; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED POLYMERIZATION; CORE/SHELL; DEGREE OF POLYMERIZATION; DOXORUBICIN; DRUG DELIVERY SYSTEM; ETHYLENE OXIDES; FUNCTIONALIZED; HEPG2 CELLS; HYDROPHOBIC INTERACTIONS; LOADING EFFICIENCY; MOLECULAR BRUSHES; NON-SPHERICAL; PCL-B-PEO; POLYMER BRUSHES; POLYMETHACRYLATES; RELEASE RATE; SPHERICAL MICELLES; WATERSOLUBLE; WORM-LIKE POLYMERS;

CONFOCAL MICROSCOPY; GRAFT COPOLYMERS; GRAFTING (CHEMICAL); POLYETHYLENE OXIDES; POLYMERIZATION; POLYMERS;

DRUG DELIVERY;

DRUG CARRIER; NANOMATERIAL; POLYESTER; POLYETHYLENE OXIDE POLYCAPROLACTONE COPOLYMER; POLYETHYLENE OXIDE-POLYCAPROLACTONE COPOLYMER; POLYMER;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DELIVERY SYSTEM; INSTRUMENTATION; SYNTHESIS;

DRUG CARRIERS; DRUG DELIVERY SYSTEMS; MOLECULAR STRUCTURE; NANOSTRUCTURES; POLYESTERS; POLYMERS;

EID: 84864998581     PISSN: 10221336     EISSN: 15213927     Source Type: Journal    
DOI: 10.1002/marc.201200172     Document Type: Article

References (31)

1. H. J. Yoon, W. D. Jang, J. Mater. Chem. 2010, 20, 211.
2. K. Kataoka, A. Harada, Y. Nagasaki, Adv. Drug Delivery Rev. 2001, 47, 113.
3. G. S. Kwon, K. Kataoka, Adv. Drug Delivery Rev. 1995, 16, 295.
4. A. S. Mikhail, C. Allen, J. Controlled Release 2009, 138, 214.
5. X. T. Shuai, H. Aia, N. Nasongkla, S. Kim, J. M. Gao, J. Controlled Release 2004, 98, 415.
6. A. D'Emanuele, D. Attwood, Adv. Drug Delivery Rev. 2005, 57, 2147.
7. D. Peer, J. M. Karp, S. Hong, O. C. Farokhzad, R. Margalit, R. Langer, Nat. Nanotechnol. 2007, 2, 751.
8. G. S. Kwon, T. Okano, Adv. Drug Delivery Rev. 1996, 21, 107.
9. O. Harush-Frenkel, E. Rozentur, S. Benita, Y. Altschuler, Biomacromolecules 2008, 9, 435.
10. G. Sahay, D. Y. Alakhova, A. V. Kabanov, J. Controlled Release 2010, 145, 182.
11. S. S. Cai, K. Vijayan, D. Cheng, E. M. Lima, D. E. Discher, Pharm. Res. 2007, 24, 2099.
12. Y. Geng, P. Dalhaimer, S. S. Cai, R. Tsai, M. Tewari, T. Minko, D. E. Discher, Nat. Nanotechnol. 2007, 2, 249.
13. K. Zhang, H. F. Fang, Z. Y. Chen, J. S. A. Taylor, K. L. Wooley, Bioconjugate Chem. 2008, 19, 1880.
14. F. Gu, L. Zhang, B. A. Teply, N. Mann, A. Wang, A. F. Radovic-Moreno, R. Langer, O. C. Farokhzad, Proc. Natl. Acad. Sci. USA 2008, 105, 2586.
15. S. E. A. Gratton, P. A. Ropp, P. D. Pohlhaus, J. C. Luft, V. J. Madden, M. E. Napier, J. M. DeSimone, Proc. Natl. Acad. Sci. USA 2008, 105, 11613.
16. J. A. Champion, S. Mitragotri, Proc. Natl. Acad. Sci. USA 2006, 103, 4930.
17. P. Decuzzi, R. Pasqualini, W. Arap, M. Ferrari, Pharm. Res. 2009, 26, 235.
18. K. Yang, Y. Q. Ma, Nat. Nanotechnol. 2010, 5, 579.
19. R. A. Petros, J. M. DeSimone, Nat. Rev. Drug Discov. 2010, 9, 615.
20. D. A. Christian, S. S. Cai, O. B. Garbuzenko, T. Harada, A. L. Zajac, T. Minko, D. E. Discher, Mol. Pharm. 2009, 6, 1343.
21. S. S. Sheiko, B. S. Sumerlin, K. Matyjaszewski, Prog. Polym. Sci. 2008, 33, 759.
22. J. A. Johnson, Y. Y. Lu, A. O. Burts, Y. Xia, A. C. Durrell, D. A. Tirrell, R. H. Grubbs, Macromolecules 2010, 43, 10326.
23. J. A. Johnson, Y. Y. Lu, A. O. Burts, Y. H. Lim, M. G. Finn, J. T. Koberstein, N. J. Turro, D. A. Tirrell, R. H. Grubbs, J. Am. Chem. Soc. 2011, 133, 559.
24. J. Z. Du, L. Y. Tang, W. J. Song, Y. Shi, J. Wang, Biomacromolecules 2009, 10, 2169.
25. Y. Yu, J. Zou, L. Yu, W. Ji, Y. Li, W. C. Law, C. Cheng, Macromolecules 2011, 44, 4793.
26. J. Zou, G. Jafr, E. Themistou, Y. Yap, Z. A. P. Wintrob, P. Alexandridis, A. C. Ceacareanu, C. Cheng, Chem. Commun. 2011, 47, 4493.
27. W. L. Zhang, Y. L. Li, L. X. Liu, Q. Q. Sun, X. T. Shuai, W. Zhu, Y. M. Chen, Biomacromolecules 2010, 11, 1331.
28. H. Zhu, G. H. Deng, Y. M. Chen, Polymer 2008, 49, 405.
29. H. Wang, H. R. Song, Y. Cui, Y. J. Deng, X. S. Chen, Chin. J. Polym. Sci. 2011, 29, 173.
30. P. Zhao, Y. C. Yan, X. Q. Feng, L. X. Liu, C. Wang, Y. M. Chen, Polymer 2012, 53, 1992.
31. M. Wintermantel, M. Gerle, K. Fischer, M. Schmidt, I. Wataoka, H. Urakawa, K. Kajiwara, Y. Tsukahara, Macromolecules 1996, 29, 978.