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Volumn 232, Issue 8, 2007, Pages 1090-1099

Doxorubicin and β-lapachone release and interaction with micellar core materials: Experiment and modeling

Author keywords

Drug release; Drug polymer interactions; Mathematical modeling; Physicochemical properties; Polymer micelles

Indexed keywords

BETA LAPACHONE; DOXORUBICIN; DRUG CARRIER; MACROGOL; POLY DEXTRO LACTIDE; POLYCAPROLACTONE; POLYMER; UNCLASSIFIED DRUG;

EID: 34548462205     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0702-RM-31     Document Type: Article
Times cited : (64)

References (58)
  • 2
    • 8144225129 scopus 로고    scopus 로고
    • Self-assembly and characterization of paclitaxel-loaded N-octyl-O-sulfate chitosan micellar system
    • Zhang C, Ping QN, Zhang HJ. Self-assembly and characterization of paclitaxel-loaded N-octyl-O-sulfate chitosan micellar system. Colloids Surf B Biointerfaces 39:69-75, 2004.
    • (2004) Colloids Surf B Biointerfaces , vol.39 , pp. 69-75
    • Zhang, C.1    Ping, Q.N.2    Zhang, H.J.3
  • 3
    • 0037148660 scopus 로고    scopus 로고
    • Polyether-polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations
    • Liggins RT, Burt HM. Polyether-polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations. Adv Drug Deliv Rev 54:191-202, 2002.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 191-202
    • Liggins, R.T.1    Burt, H.M.2
  • 4
    • 0029980834 scopus 로고    scopus 로고
    • Development of amphiphilic diblock copolymers as micellar carriers of taxol
    • Zhang XC, Jackson JK, Burt HM. Development of amphiphilic diblock copolymers as micellar carriers of taxol. Int J Pharm 132:195-206, 1996.
    • (1996) Int J Pharm , vol.132 , pp. 195-206
    • Zhang, X.C.1    Jackson, J.K.2    Burt, H.M.3
  • 5
    • 33845388144 scopus 로고    scopus 로고
    • Micellar nanocarriers: Pharmaceutical perspectives
    • Torchilin VP. Micellar nanocarriers: pharmaceutical perspectives. Pharm Res 24:1-16, 2007.
    • (2007) Pharm Res , vol.24 , pp. 1-16
    • Torchilin, V.P.1
  • 6
    • 1642541103 scopus 로고    scopus 로고
    • Polymeric micelles for delivery of poorly water-soluble compounds
    • Kwon GS. Polymeric micelles for delivery of poorly water-soluble compounds. Crit Rev Ther Drug Carrier Syst 20:357-403, 2003.
    • (2003) Crit Rev Ther Drug Carrier Syst , vol.20 , pp. 357-403
    • Kwon, G.S.1
  • 7
    • 34249023676 scopus 로고    scopus 로고
    • Functionalized micellar systems for cancer targeted drug delivery
    • Sutton D, Nasongkla N, Blanco E, Gao J. Functionalized micellar systems for cancer targeted drug delivery. Pharm Res 24:1029-1046, 2007.
    • (2007) Pharm Res , vol.24 , pp. 1029-1046
    • Sutton, D.1    Nasongkla, N.2    Blanco, E.3    Gao, J.4
  • 9
    • 2542559832 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies
    • Kim TY, Kim DW, Chung JY, Shin SG, Kim SC, Heo DS, Kim NK, Bang YJ. Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies. Clin Cancer Res 10:3708-3716, 2004.
    • (2004) Clin Cancer Res , vol.10 , pp. 3708-3716
    • Kim, T.Y.1    Kim, D.W.2    Chung, J.Y.3    Shin, S.G.4    Kim, S.C.5    Heo, D.S.6    Kim, N.K.7    Bang, Y.J.8
  • 10
    • 0028470454 scopus 로고
    • Barriers to drug-delivery in solid tumors
    • Jain RK. Barriers to drug-delivery in solid tumors. Sci Am 271:58-65, 1994.
    • (1994) Sci Am , vol.271 , pp. 58-65
    • Jain, R.K.1
  • 13
    • 0035850224 scopus 로고    scopus 로고
    • Structure and design of polymeric surfactant-based drug delivery systems
    • Torchilin VP. Structure and design of polymeric surfactant-based drug delivery systems. J Control Release 73:137-172, 2001.
    • (2001) J Control Release , vol.73 , pp. 137-172
    • Torchilin, V.P.1
  • 14
    • 0033980297 scopus 로고    scopus 로고
    • Doxorubicin-loaded poly (ethylene glycol)-poly(beta-benzyl- l-aspartate) copolymer micelles: Their pharmaceutical characteristics and biological significance
    • Kataoka K, Matsumoto T, Yokoyama M, Okano T, Sakurai Y, Fukushima S, Okamoto K, Kwon GS. Doxorubicin-loaded poly (ethylene glycol)-poly(beta-benzyl- l-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance. J Control Release 64:143-153, 2000.
    • (2000) J Control Release , vol.64 , pp. 143-153
    • Kataoka, K.1    Matsumoto, T.2    Yokoyama, M.3    Okano, T.4    Sakurai, Y.5    Fukushima, S.6    Okamoto, K.7    Kwon, G.S.8
  • 15
    • 29244477993 scopus 로고    scopus 로고
    • In vitro release of the mTOR inhibitor rapamycin from poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles
    • Forrest ML, Won CY, Malick AW, Kwon GS. In vitro release of the mTOR inhibitor rapamycin from poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles. J Control Release 110:370-377, 2006.
    • (2006) J Control Release , vol.110 , pp. 370-377
    • Forrest, M.L.1    Won, C.Y.2    Malick, A.W.3    Kwon, G.S.4
  • 16
    • 0346494420 scopus 로고    scopus 로고
    • Polymer-drug compatibility: A guide to the development of delivery systems for the anticancer agent, Ellipticine
    • Liu JB, Xiao YH, Allen C. Polymer-drug compatibility: A guide to the development of delivery systems for the anticancer agent, Ellipticine. J Pharm Sci 93:132-143, 2004.
    • (2004) J Pharm Sci , vol.93 , pp. 132-143
    • Liu, J.B.1    Xiao, Y.H.2    Allen, C.3
  • 17
    • 4143074645 scopus 로고    scopus 로고
    • Micellar carriers based on block copolymers of poly(e-caprolactone) and poly(ethylene glycol) for doxorubicin delivery
    • Shuai XT, Ai H, Nasongkla N, Kim S, Gao JM. Micellar carriers based on block copolymers of poly(e-caprolactone) and poly(ethylene glycol) for doxorubicin delivery. J Control Release 98:415-426, 2004.
    • (2004) J Control Release , vol.98 , pp. 415-426
    • Shuai, X.T.1    Ai, H.2    Nasongkla, N.3    Kim, S.4    Gao, J.M.5
  • 18
    • 0037130252 scopus 로고    scopus 로고
    • Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages
    • Yoo HS, Lee EA, Park TG. Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages. J Control Release 82:17-27, 2002.
    • (2002) J Control Release , vol.82 , pp. 17-27
    • Yoo, H.S.1    Lee, E.A.2    Park, T.G.3
  • 19
    • 14844303778 scopus 로고    scopus 로고
    • Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor
    • Lee ES, Na K, Bae YH. Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor. J Control Release 103: 405-418, 2005.
    • (2005) J Control Release , vol.103 , pp. 405-418
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 20
    • 33749073801 scopus 로고    scopus 로고
    • Remote loading of doxorubicin into liposomes driven by a transmembrane phosphate gradient
    • Fritze A, Hens F, Kimpfler A, Schubert R, Peschka-Suss R. Remote loading of doxorubicin into liposomes driven by a transmembrane phosphate gradient. BBA-Biomembranes 1758:1633-1640, 2006.
    • (2006) BBA-Biomembranes , vol.1758 , pp. 1633-1640
    • Fritze, A.1    Hens, F.2    Kimpfler, A.3    Schubert, R.4    Peschka-Suss, R.5
  • 22
    • 0032778659 scopus 로고    scopus 로고
    • Polymeric micelles: A new generation of colloidal drug carriers
    • Jones MC, Leroux JC. Polymeric micelles: a new generation of colloidal drug carriers. Eur J Pharm Biopharm 48:101-111, 1999.
    • (1999) Eur J Pharm Biopharm , vol.48 , pp. 101-111
    • Jones, M.C.1    Leroux, J.C.2
  • 23
    • 33845214383 scopus 로고    scopus 로고
    • Lipophilic prodrugs of Hsp90 inhibitor geldanamycin for nanoencapsulation in poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles
    • Forrest ML, Zhao A, Won CY, Malick AW, Kwon GS. Lipophilic prodrugs of Hsp90 inhibitor geldanamycin for nanoencapsulation in poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles. J Control Release 116:139-149, 2006.
    • (2006) J Control Release , vol.116 , pp. 139-149
    • Forrest, M.L.1    Zhao, A.2    Won, C.Y.3    Malick, A.W.4    Kwon, G.S.5
  • 24
    • 14644411706 scopus 로고    scopus 로고
    • Stereocomplex block copolymer micelles: Core-shell nanostructures with enhanced stability
    • Kang N, Perron ME, Prud'homme RE, Zhang YB, Gaucher G, Leroux JC. Stereocomplex block copolymer micelles: core-shell nanostructures with enhanced stability. Nano Lett 5:315-319, 2005.
    • (2005) Nano Lett , vol.5 , pp. 315-319
    • Kang, N.1    Perron, M.E.2    Prud'homme, R.E.3    Zhang, Y.B.4    Gaucher, G.5    Leroux, J.C.6
  • 25
    • 0035967645 scopus 로고    scopus 로고
    • Physicochemical evaluation of nanoparticles assembled from poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) block copolymers as drug delivery vehicles
    • Riley T, Stolnik S, Heald CR, Xiong CD, Garnett MC, Illum L, Davis SS, Purkiss SC, Barlow RJ, Gellert PR. Physicochemical evaluation of nanoparticles assembled from poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) block copolymers as drug delivery vehicles. Langmuir 17: 3168-3174, 2001.
    • (2001) Langmuir , vol.17 , pp. 3168-3174
    • Riley, T.1    Stolnik, S.2    Heald, C.R.3    Xiong, C.D.4    Garnett, M.C.5    Illum, L.6    Davis, S.S.7    Purkiss, S.C.8    Barlow, R.J.9    Gellert, P.R.10
  • 26
    • 0026059172 scopus 로고
    • Physicomechanical properties of degradable polymers used in medical applications: A comparative-study
    • Engelberg I, Kohn J. Physicomechanical properties of degradable polymers used in medical applications: a comparative-study. Biomaterials 12:292-304, 1991.
    • (1991) Biomaterials , vol.12 , pp. 292-304
    • Engelberg, I.1    Kohn, J.2
  • 27
    • 0024137697 scopus 로고
    • Thermal characterization of polylactides
    • Jamshidi K, Hyon SH, Ikada Y. Thermal characterization of polylactides. Polymer 29:2229-2234, 1988.
    • (1988) Polymer , vol.29 , pp. 2229-2234
    • Jamshidi, K.1    Hyon, S.H.2    Ikada, Y.3
  • 28
    • 0030176475 scopus 로고    scopus 로고
    • Diffusional release of a dispersed solute from a spherical polymer matrix
    • Abdekhodaie MJ, Cheng YL. Diffusional release of a dispersed solute from a spherical polymer matrix. J Membr Sci 115:171-178, 1996.
    • (1996) J Membr Sci , vol.115 , pp. 171-178
    • Abdekhodaie, M.J.1    Cheng, Y.L.2
  • 30
    • 0035844738 scopus 로고    scopus 로고
    • Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC)
    • Siepmann J, Peppas NA. Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Adv Drug Deliv Rev 48:139-157, 2001.
    • (2001) Adv Drug Deliv Rev , vol.48 , pp. 139-157
    • Siepmann, J.1    Peppas, N.A.2
  • 31
    • 2942557097 scopus 로고    scopus 로고
    • Theoretical analysis of drug release into a finite medium from sphere ensembles with various size and concentration distributions
    • Zhou Y, Chu JS, Wu XY. Theoretical analysis of drug release into a finite medium from sphere ensembles with various size and concentration distributions. Eur J Pharm Sci 22:251-259, 2004.
    • (2004) Eur J Pharm Sci , vol.22 , pp. 251-259
    • Zhou, Y.1    Chu, J.S.2    Wu, X.Y.3
  • 32
    • 0034738837 scopus 로고    scopus 로고
    • Drug release from an ensemble of swellable crosslinked polymer particles
    • Grassi M, Colombo I, Lapasin R. Drug release from an ensemble of swellable crosslinked polymer particles. J Control Release 68:97-113, 2000.
    • (2000) J Control Release , vol.68 , pp. 97-113
    • Grassi, M.1    Colombo, I.2    Lapasin, R.3
  • 33
    • 0038399818 scopus 로고    scopus 로고
    • Controlled drug delivery from swellable hydroxypropylmethylcellulose matrices: Model-based analysis of observed radial front movements
    • Kiil S, Dam-Johansen K. Controlled drug delivery from swellable hydroxypropylmethylcellulose matrices: model-based analysis of observed radial front movements. J Control Release 90:1-21, 2003.
    • (2003) J Control Release , vol.90 , pp. 1-21
    • Kiil, S.1    Dam-Johansen, K.2
  • 34
    • 0344893332 scopus 로고
    • Mechanism of sustained-action medication
    • Higuchi T. Mechanism of sustained-action medication. J Pharm Sci 52: 1145-1149, 1963.
    • (1963) J Pharm Sci , vol.52 , pp. 1145-1149
    • Higuchi, T.1
  • 35
    • 0023195932 scopus 로고
    • A simple equation for description of solute release I: Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs
    • Ritger PL, Peppas NA. A simple equation for description of solute release I: Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J Control Release 5:23-36, 1987.
    • (1987) J Control Release , vol.5 , pp. 23-36
    • Ritger, P.L.1    Peppas, N.A.2
  • 36
    • 0004020231 scopus 로고
    • New York: Oxford University Press, pp
    • Crank J. The Mathematics of Diffusion. New York: Oxford University Press, pp89-103, 1975.
    • (1975) The Mathematics of Diffusion , pp. 89-103
    • Crank, J.1
  • 38
    • 34548432186 scopus 로고    scopus 로고
    • Doxorubicin hydrochloride
    • Available at:, Accessed March
    • Sigma-Aldrich. Doxorubicin hydrochloride. In: product detail. Available at: www.sigmaaldrich.com. Accessed March 2006.
    • (2006) product detail
    • Sigma-Aldrich1
  • 39
    • 0026240517 scopus 로고
    • Asymptotic-behavior and long-range interactions in aqueous-solutions of poly(ethylene oxide)
    • Devanand K, Selser JC. Asymptotic-behavior and long-range interactions in aqueous-solutions of poly(ethylene oxide). Macromolecules 24:5943-5947, 1991.
    • (1991) Macromolecules , vol.24 , pp. 5943-5947
    • Devanand, K.1    Selser, J.C.2
  • 40
    • 0026838890 scopus 로고
    • Adsorbed polymer layer thickness determination at the solid liquid interface by different techniques
    • Siffert B, Li JF. Adsorbed polymer layer thickness determination at the solid liquid interface by different techniques. Colloids Surf 62:307-314, 1992.
    • (1992) Colloids Surf , vol.62 , pp. 307-314
    • Siffert, B.1    Li, J.F.2
  • 41
    • 0142089168 scopus 로고    scopus 로고
    • Johnson BK, Prud'homme RK. Mechanism for rapid self-assembly of block copolymer nanoparticles. Phys Rev Let 91:1183021-1183024, 2003.
    • Johnson BK, Prud'homme RK. Mechanism for rapid self-assembly of block copolymer nanoparticles. Phys Rev Let 91:1183021-1183024, 2003.
  • 42
    • 0004020231 scopus 로고
    • New York: Oxford University Press, p
    • Crank J. The Mathematics of Diffusion. New York: Oxford University Press, p44-68, 1975.
    • (1975) The Mathematics of Diffusion , pp. 44-68
    • Crank, J.1
  • 43
    • 18244412129 scopus 로고    scopus 로고
    • There is no evidence for the existence of complex formation between doxorubicin and glutathione
    • Marszalek M, Bartosz M, Bartosz G. There is no evidence for the existence of complex formation between doxorubicin and glutathione. Cell Mol Biol Lett 8:311-315, 2003.
    • (2003) Cell Mol Biol Lett , vol.8 , pp. 311-315
    • Marszalek, M.1    Bartosz, M.2    Bartosz, G.3
  • 44
    • 0037082709 scopus 로고    scopus 로고
    • Poly(D,L-lactic acid) surfaces modified by silk fibroin: Effects on the culture of osteoblast in vitro
    • Cai KY, Yao KD, Lin SB, Yang ZM, Li XQ, Xie HQ, Qing TW, Gao LB. Poly(D,L-lactic acid) surfaces modified by silk fibroin: effects on the culture of osteoblast in vitro. Biomaterials 23:1153-1160, 2002.
    • (2002) Biomaterials , vol.23 , pp. 1153-1160
    • Cai, K.Y.1    Yao, K.D.2    Lin, S.B.3    Yang, Z.M.4    Li, X.Q.5    Xie, H.Q.6    Qing, T.W.7    Gao, L.B.8
  • 45
    • 12444259723 scopus 로고    scopus 로고
    • Human skin cell cultures onto PLA(50) (PDLLA) bioresorbable polymers: Influence of chemical and morphological surface modifications
    • Garric X, Moles JP, Garreau H, Guilhou JJ, Vert M. Human skin cell cultures onto PLA(50) (PDLLA) bioresorbable polymers: influence of chemical and morphological surface modifications. J Biomed Mater Res A 72A:180-189, 2005.
    • (2005) J Biomed Mater Res A , vol.72 A , pp. 180-189
    • Garric, X.1    Moles, J.P.2    Garreau, H.3    Guilhou, J.J.4    Vert, M.5
  • 46
    • 4444247465 scopus 로고    scopus 로고
    • Laser surface modification of poly(epsilon-caprolactone) (PCL) membrane for tissue engineering applications
    • Tiaw KS, Goh SW, Hong M, Wang Z, Lan B, Teoh SH. Laser surface modification of poly(epsilon-caprolactone) (PCL) membrane for tissue engineering applications. Biomaterials 26:763-769, 2005.
    • (2005) Biomaterials , vol.26 , pp. 763-769
    • Tiaw, K.S.1    Goh, S.W.2    Hong, M.3    Wang, Z.4    Lan, B.5    Teoh, S.H.6
  • 47
  • 48
    • 0035808052 scopus 로고    scopus 로고
    • Swelling of poly(DL-lactide) and polylactide-co-glycolide in humid environments
    • Sharp JS, Forrest JA, Jones RAL. Swelling of poly(DL-lactide) and polylactide-co-glycolide in humid environments. Macromolecules 34: 8752-8760, 2001.
    • (2001) Macromolecules , vol.34 , pp. 8752-8760
    • Sharp, J.S.1    Forrest, J.A.2    Jones, R.A.L.3
  • 49
    • 0030082755 scopus 로고    scopus 로고
    • Surface properties and drug release behavior of polycaprolactone polyether blend and copolymer
    • Bei JZ, Wang WH, Wang ZF, Wang SG. Surface properties and drug release behavior of polycaprolactone polyether blend and copolymer. Polym Adv Technol 7:104-107, 1996.
    • (1996) Polym Adv Technol , vol.7 , pp. 104-107
    • Bei, J.Z.1    Wang, W.H.2    Wang, Z.F.3    Wang, S.G.4
  • 50
    • 13844269029 scopus 로고    scopus 로고
    • Polymeric micellar pH-sensitive drug delivery system for doxorubicin
    • Hruby M, Konak C, Ulbrich K. Polymeric micellar pH-sensitive drug delivery system for doxorubicin. J Control Release 103:137-148, 2005.
    • (2005) J Control Release , vol.103 , pp. 137-148
    • Hruby, M.1    Konak, C.2    Ulbrich, K.3
  • 52
    • 0021249685 scopus 로고
    • Self-association of doxorubicin and related-compounds in aqueous-solution
    • Menozzi M, Valentini L, Vannini E, Arcamone F. Self-association of doxorubicin and related-compounds in aqueous-solution. J Pharm Sci 73:766-770, 1984.
    • (1984) J Pharm Sci , vol.73 , pp. 766-770
    • Menozzi, M.1    Valentini, L.2    Vannini, E.3    Arcamone, F.4
  • 53
    • 15244345124 scopus 로고    scopus 로고
    • pH-responsive copolymer assemblies for controlled release of doxorubicin
    • Gillies ER, Frechet JMJ. pH-responsive copolymer assemblies for controlled release of doxorubicin. Bioconjug Chem 16:361-368, 2005.
    • (2005) Bioconjug Chem , vol.16 , pp. 361-368
    • Gillies, E.R.1    Frechet, J.M.J.2
  • 55
    • 33748307496 scopus 로고    scopus 로고
    • Doxorubicin encapsulation and diffusional release from stable, polymeric, hydrogel nanoparticles
    • Missirlis D, Kawamura R, Tirelli N, Hubbell JA. Doxorubicin encapsulation and diffusional release from stable, polymeric, hydrogel nanoparticles. Eur J Pharm Sci 29:120-129, 2006.
    • (2006) Eur J Pharm Sci , vol.29 , pp. 120-129
    • Missirlis, D.1    Kawamura, R.2    Tirelli, N.3    Hubbell, J.A.4
  • 56
    • 0021978742 scopus 로고
    • Doxorubicin decomposition on storage: Effect of pH, type of buffer and liposome encapsulation
    • Janssen MJH, Crommelin DJA, Storm G, Hulshoff A. Doxorubicin decomposition on storage: effect of pH, type of buffer and liposome encapsulation. Int J Pharm 23:1-11, 1985.
    • (1985) Int J Pharm , vol.23 , pp. 1-11
    • Janssen, M.J.H.1    Crommelin, D.J.A.2    Storm, G.3    Hulshoff, A.4
  • 57
    • 34548411795 scopus 로고    scopus 로고
    • Impact, version 4.0. User's manual. New York: Schrödinger, LLC, 2005.
    • Impact, version 4.0. User's manual. New York: Schrödinger, LLC, 2005.
  • 58
    • 0037059206 scopus 로고    scopus 로고
    • Incorporation and release of hydrophobic probes in biocompatible polycaprolactone-block-poly (ethylene oxide) micelles: Implications for drug delivery
    • Soo PL, Luo LB, Maysinger D, Eisenberg A. Incorporation and release of hydrophobic probes in biocompatible polycaprolactone-block-poly (ethylene oxide) micelles: implications for drug delivery. Langmuir 18: 9996-10004, 2002.
    • (2002) Langmuir , vol.18 , pp. 9996-10004
    • Soo, P.L.1    Luo, L.B.2    Maysinger, D.3    Eisenberg, A.4


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