메뉴 건너뛰기




Volumn 1842, Issue 12, 2014, Pages 2427-2438

Improvement of neuronal bioenergetics by neurosteroids: Implications for age-related neurodegenerative disorders

Author keywords

Bioenergetics; Mitochondria; Neurosteroid; Redox homeostasis

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; ADENOSINE TRIPHOSPHATE; ANDROGEN RECEPTOR ANTAGONIST; ANDROSTANEDIOL; ESTRADIOL; ESTRONE; HORMONE RECEPTOR BLOCKING AGENT; MANGANESE SUPEROXIDE DISMUTASE; MIFEPRISTONE; MITOCHONDRIAL REACTIVE OXYGEN SPECIES; NEUROSTEROID; PRASTERONE; PROGESTERONE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TESTOSTERONE; UNCLASSIFIED DRUG; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ELTANOLONE; SUPEROXIDE DISMUTASE;

EID: 84910044705     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.09.013     Document Type: Article
Times cited : (94)

References (64)
  • 1
    • 3242737585 scopus 로고    scopus 로고
    • Energetic basis of brain activity: implications for neuroimaging
    • Shulman R.G., Rothman D.L., Behar K.L., Hyder F. Energetic basis of brain activity: implications for neuroimaging. Trends Neurosci. 2004, 27:489-495.
    • (2004) Trends Neurosci. , vol.27 , pp. 489-495
    • Shulman, R.G.1    Rothman, D.L.2    Behar, K.L.3    Hyder, F.4
  • 3
    • 57049143140 scopus 로고    scopus 로고
    • Mitochondria in neuroplasticity and neurological disorders
    • Mattson M.P., Gleichmann M., Cheng A. Mitochondria in neuroplasticity and neurological disorders. Neuron 2008, 60:748-766.
    • (2008) Neuron , vol.60 , pp. 748-766
    • Mattson, M.P.1    Gleichmann, M.2    Cheng, A.3
  • 6
    • 84868127393 scopus 로고    scopus 로고
    • From mitochondrial dysfunction to amyloid beta formation: novel insights into the pathogenesis of Alzheimer's disease
    • Leuner K., Muller W.E., Reichert A.S. From mitochondrial dysfunction to amyloid beta formation: novel insights into the pathogenesis of Alzheimer's disease. Mol. Neurobiol. 2012, 46:186-193.
    • (2012) Mol. Neurobiol. , vol.46 , pp. 186-193
    • Leuner, K.1    Muller, W.E.2    Reichert, A.S.3
  • 7
    • 77955089623 scopus 로고    scopus 로고
    • Mitochondrial dysfunction: common final pathway in brain aging and Alzheimer's disease-therapeutic aspects
    • Muller W.E., Eckert A., Kurz C., Eckert G.P., Leuner K. Mitochondrial dysfunction: common final pathway in brain aging and Alzheimer's disease-therapeutic aspects. Mol. Neurobiol. 2010, 41:159-171.
    • (2010) Mol. Neurobiol. , vol.41 , pp. 159-171
    • Muller, W.E.1    Eckert, A.2    Kurz, C.3    Eckert, G.P.4    Leuner, K.5
  • 12
    • 0032956181 scopus 로고    scopus 로고
    • Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system
    • Mensah-Nyagan A.G., Do-Rego J.L., Beaujean D., V.Luu-The, Pelletier G., Vaudry H. Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system. Pharmacol. Rev. 1999, 51:63-81.
    • (1999) Pharmacol. Rev. , vol.51 , pp. 63-81
    • Mensah-Nyagan, A.G.1    Do-Rego, J.L.2    Beaujean, D.3    V.Luu-The Pelletier, G.4    Vaudry, H.5
  • 14
    • 0037213976 scopus 로고    scopus 로고
    • Oxidative stress-mediated DHEA formation in Alzheimer's disease pathology
    • Brown R.C., Han Z., Cascio C., Papadopoulos V. Oxidative stress-mediated DHEA formation in Alzheimer's disease pathology. Neurobiol. Aging 2003, 24:57-65.
    • (2003) Neurobiol. Aging , vol.24 , pp. 57-65
    • Brown, R.C.1    Han, Z.2    Cascio, C.3    Papadopoulos, V.4
  • 16
    • 33744497811 scopus 로고    scopus 로고
    • 3alpha,5alpha-THP: a potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia
    • Smith C.D., Wekstein D.R., Markesbery W.R., Frye C.A. 3alpha,5alpha-THP: a potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia. Psychopharmacology (Berl) 2006, 186:481-485.
    • (2006) Psychopharmacology (Berl) , vol.186 , pp. 481-485
    • Smith, C.D.1    Wekstein, D.R.2    Markesbery, W.R.3    Frye, C.A.4
  • 18
    • 40949142713 scopus 로고    scopus 로고
    • Dose-dependent and sequence-sensitive effects of amyloid-beta peptide on neurosteroidogenesis in human neuroblastoma cells
    • Schaeffer V., Meyer L., Patte-Mensah C., Eckert A., Mensah-Nyagan A.G. Dose-dependent and sequence-sensitive effects of amyloid-beta peptide on neurosteroidogenesis in human neuroblastoma cells. Neurochem. Int. 2008, 52:948-955.
    • (2008) Neurochem. Int. , vol.52 , pp. 948-955
    • Schaeffer, V.1    Meyer, L.2    Patte-Mensah, C.3    Eckert, A.4    Mensah-Nyagan, A.G.5
  • 19
    • 33745791723 scopus 로고    scopus 로고
    • Modulation of neurosteroid production in human neuroblastoma cells by Alzheimer's disease key proteins
    • Schaeffer V., Patte-Mensah C., Eckert A., Mensah-Nyagan A.G. Modulation of neurosteroid production in human neuroblastoma cells by Alzheimer's disease key proteins. J. Neurobiol. 2006, 66:868-881.
    • (2006) J. Neurobiol. , vol.66 , pp. 868-881
    • Schaeffer, V.1    Patte-Mensah, C.2    Eckert, A.3    Mensah-Nyagan, A.G.4
  • 21
    • 84868115047 scopus 로고    scopus 로고
    • Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationship
    • Grimm A., Lim Y.A., Mensah-Nyagan A.G., Gotz J., Eckert A. Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationship. Mol. Neurobiol. 2012, 46:151-160.
    • (2012) Mol. Neurobiol. , vol.46 , pp. 151-160
    • Grimm, A.1    Lim, Y.A.2    Mensah-Nyagan, A.G.3    Gotz, J.4    Eckert, A.5
  • 23
    • 38449089795 scopus 로고    scopus 로고
    • Estradiol in vivo regulation of brain mitochondrial proteome
    • Nilsen J., Irwin R.W., Gallaher T.K., Brinton R.D. Estradiol in vivo regulation of brain mitochondrial proteome. J. Neurosci. 2007, 27:14069-14077.
    • (2007) J. Neurosci. , vol.27 , pp. 14069-14077
    • Nilsen, J.1    Irwin, R.W.2    Gallaher, T.K.3    Brinton, R.D.4
  • 24
    • 84861895505 scopus 로고    scopus 로고
    • Ovarian hormone loss induces bioenergetic deficits and mitochondrial beta-amyloid
    • Yao J., Irwin R., Chen S., Hamilton R., Cadenas E., Brinton R.D. Ovarian hormone loss induces bioenergetic deficits and mitochondrial beta-amyloid. Neurobiol. Aging 2012, 33:1507-1521.
    • (2012) Neurobiol. Aging , vol.33 , pp. 1507-1521
    • Yao, J.1    Irwin, R.2    Chen, S.3    Hamilton, R.4    Cadenas, E.5    Brinton, R.D.6
  • 25
    • 79953116520 scopus 로고    scopus 로고
    • Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease
    • Rosario E.R., Chang L., Head E.H., Stanczyk F.Z., Pike C.J. Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease. Neurobiol. Aging 2011, 32:604-613.
    • (2011) Neurobiol. Aging , vol.32 , pp. 604-613
    • Rosario, E.R.1    Chang, L.2    Head, E.H.3    Stanczyk, F.Z.4    Pike, C.J.5
  • 27
    • 68149148549 scopus 로고    scopus 로고
    • Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells
    • Rhein V., Baysang G., Rao S., Meier F., Bonert A., Muller-Spahn F., Eckert A. Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells. Cell. Mol. Neurobiol. 2009, 29:1063-1071.
    • (2009) Cell. Mol. Neurobiol. , vol.29 , pp. 1063-1071
    • Rhein, V.1    Baysang, G.2    Rao, S.3    Meier, F.4    Bonert, A.5    Muller-Spahn, F.6    Eckert, A.7
  • 29
    • 84878443230 scopus 로고    scopus 로고
    • Estradiol and testosterone regulate arginine-vasopressin expression in SH-SY5Y human female neuroblastoma cells through estrogen receptors-alpha and -beta
    • Grassi D., Bellini M.J., Acaz-Fonseca E., Panzica G., Garcia-Segura L.M. Estradiol and testosterone regulate arginine-vasopressin expression in SH-SY5Y human female neuroblastoma cells through estrogen receptors-alpha and -beta. Endocrinology 2013, 154:2092-2100.
    • (2013) Endocrinology , vol.154 , pp. 2092-2100
    • Grassi, D.1    Bellini, M.J.2    Acaz-Fonseca, E.3    Panzica, G.4    Garcia-Segura, L.M.5
  • 31
    • 79955977746 scopus 로고    scopus 로고
    • Dehydroepiandrosterone protects against oxidative stress-induced endothelial dysfunction in ovariectomized rats
    • Camporez J.P., Akamine E.H., Davel A.P., Franci C.R., Rossoni L.V., Carvalho C.R. Dehydroepiandrosterone protects against oxidative stress-induced endothelial dysfunction in ovariectomized rats. J. Physiol. 2011, 589:2585-2596.
    • (2011) J. Physiol. , vol.589 , pp. 2585-2596
    • Camporez, J.P.1    Akamine, E.H.2    Davel, A.P.3    Franci, C.R.4    Rossoni, L.V.5    Carvalho, C.R.6
  • 32
  • 33
    • 84055197904 scopus 로고    scopus 로고
    • Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function
    • Irwin R.W., Yao J., J.To, Hamilton R.T., Cadenas E., Brinton R.D. Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function. J. Neuroendocrinol. 2012, 24:236-248.
    • (2012) J. Neuroendocrinol. , vol.24 , pp. 236-248
    • Irwin, R.W.1    Yao, J.2    J.To Hamilton, R.T.3    Cadenas, E.4    Brinton, R.D.5
  • 34
    • 84894173275 scopus 로고    scopus 로고
    • Neurosteroid 3alpha-androstanediol efficiently counteracts paclitaxel-induced peripheral neuropathy and painful symptoms
    • Meyer L., Patte-Mensah C., Taleb O., Mensah-Nyagan A.G. Neurosteroid 3alpha-androstanediol efficiently counteracts paclitaxel-induced peripheral neuropathy and painful symptoms. PLoS One 2013, 8:e80915.
    • (2013) PLoS One , vol.8 , pp. e80915
    • Meyer, L.1    Patte-Mensah, C.2    Taleb, O.3    Mensah-Nyagan, A.G.4
  • 35
    • 84861882571 scopus 로고    scopus 로고
    • Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice
    • Singh C., Liu L., Wang J.M., Irwin R.W., Yao J., Chen S., Henry S., Thompson R.F., Brinton R.D. Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice. Neurobiol. Aging 2012, 33:1493-1506.
    • (2012) Neurobiol. Aging , vol.33 , pp. 1493-1506
    • Singh, C.1    Liu, L.2    Wang, J.M.3    Irwin, R.W.4    Yao, J.5    Chen, S.6    Henry, S.7    Thompson, R.F.8    Brinton, R.D.9
  • 36
    • 0033973454 scopus 로고    scopus 로고
    • Crucial role of the membrane potential for ATP synthesis by F(1)F(o) ATP synthases
    • Dimroth P., Kaim G., Matthey U. Crucial role of the membrane potential for ATP synthesis by F(1)F(o) ATP synthases. J. Exp. Biol. 2000, 203:51-59.
    • (2000) J. Exp. Biol. , vol.203 , pp. 51-59
    • Dimroth, P.1    Kaim, G.2    Matthey, U.3
  • 37
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden M.G., Cantley L.C., Thompson C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 38
    • 34548639993 scopus 로고    scopus 로고
    • Neurosteroid binding sites on GABA(A) receptors
    • Hosie A.M., Wilkins M.E., Smart T.G. Neurosteroid binding sites on GABA(A) receptors. Pharmacol. Ther. 2007, 116:7-19.
    • (2007) Pharmacol. Ther. , vol.116 , pp. 7-19
    • Hosie, A.M.1    Wilkins, M.E.2    Smart, T.G.3
  • 39
    • 0030729851 scopus 로고    scopus 로고
    • High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
    • Korshunov S.S., Skulachev V.P., Starkov A.A. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett. 1997, 416:15-18.
    • (1997) FEBS Lett. , vol.416 , pp. 15-18
    • Korshunov, S.S.1    Skulachev, V.P.2    Starkov, A.A.3
  • 40
    • 0142150051 scopus 로고    scopus 로고
    • Mitochondrial formation of reactive oxygen species
    • Turrens J.F. Mitochondrial formation of reactive oxygen species. J. Physiol. 2003, 552:335-344.
    • (2003) J. Physiol. , vol.552 , pp. 335-344
    • Turrens, J.F.1
  • 41
    • 0031765501 scopus 로고    scopus 로고
    • Androgen receptor in mouse brain: sex differences and similarities in autoregulation
    • Lu S.F., McKenna S.E., Cologer-Clifford A., Nau E.A., Simon N.G. Androgen receptor in mouse brain: sex differences and similarities in autoregulation. Endocrinology 1998, 139:1594-1601.
    • (1998) Endocrinology , vol.139 , pp. 1594-1601
    • Lu, S.F.1    McKenna, S.E.2    Cologer-Clifford, A.3    Nau, E.A.4    Simon, N.G.5
  • 43
    • 0035811226 scopus 로고    scopus 로고
    • Sex differences in progesterone receptor immunoreactivity in neonatal mouse brain depend on estrogen receptor alpha expression
    • Wagner C.K., Pfau J.L., De Vries G.J., Merchenthaler I.J. Sex differences in progesterone receptor immunoreactivity in neonatal mouse brain depend on estrogen receptor alpha expression. J. Neurobiol. 2001, 47:176-182.
    • (2001) J. Neurobiol. , vol.47 , pp. 176-182
    • Wagner, C.K.1    Pfau, J.L.2    De Vries, G.J.3    Merchenthaler, I.J.4
  • 44
    • 84898487816 scopus 로고    scopus 로고
    • Novel receptor targets for production and action of allopregnanolone in the central nervous system: a focus on pregnane xenobiotic receptor
    • Frye C.A., Koonce C.J., Walf A.A. Novel receptor targets for production and action of allopregnanolone in the central nervous system: a focus on pregnane xenobiotic receptor. Front. Cell. Neurosci. 2014, 8:106.
    • (2014) Front. Cell. Neurosci. , vol.8 , pp. 106
    • Frye, C.A.1    Koonce, C.J.2    Walf, A.A.3
  • 49
    • 32544445370 scopus 로고    scopus 로고
    • The mitochondrion as a primary site of action of steroid and thyroid hormones: presence and action of steroid and thyroid hormone receptors in mitochondria of animal cells
    • Psarra A.M., Solakidi S., Sekeris C.E. The mitochondrion as a primary site of action of steroid and thyroid hormones: presence and action of steroid and thyroid hormone receptors in mitochondria of animal cells. Mol. Cell. Endocrinol. 2006, 246:21-33.
    • (2006) Mol. Cell. Endocrinol. , vol.246 , pp. 21-33
    • Psarra, A.M.1    Solakidi, S.2    Sekeris, C.E.3
  • 50
    • 84892882368 scopus 로고    scopus 로고
    • Estrogen: a master regulator of bioenergetic systems in the brain and body
    • Rettberg J.R., Yao J., Brinton R.D. Estrogen: a master regulator of bioenergetic systems in the brain and body. Front. Neuroendocrinol. 2014, 35:8-30.
    • (2014) Front. Neuroendocrinol. , vol.35 , pp. 8-30
    • Rettberg, J.R.1    Yao, J.2    Brinton, R.D.3
  • 51
    • 84886522237 scopus 로고    scopus 로고
    • Oxidative stress defines the neuroprotective or neurotoxic properties of androgens in immortalized female rat dopaminergic neuronal cells
    • Holmes S., Abbassi B., Su C., Singh M., Cunningham R.L. Oxidative stress defines the neuroprotective or neurotoxic properties of androgens in immortalized female rat dopaminergic neuronal cells. Endocrinology 2013, 154:4281-4292.
    • (2013) Endocrinology , vol.154 , pp. 4281-4292
    • Holmes, S.1    Abbassi, B.2    Su, C.3    Singh, M.4    Cunningham, R.L.5
  • 52
    • 84884954360 scopus 로고    scopus 로고
    • Actions of 17beta-estradiol and testosterone in the mitochondria and their implications in aging
    • Vasconsuelo A., Milanesi L., Boland R. Actions of 17beta-estradiol and testosterone in the mitochondria and their implications in aging. Ageing Res. Rev. 2013, 12:907-917.
    • (2013) Ageing Res. Rev. , vol.12 , pp. 907-917
    • Vasconsuelo, A.1    Milanesi, L.2    Boland, R.3
  • 53
    • 78649719759 scopus 로고    scopus 로고
    • 3alpha-Androstanediol, but not testosterone, attenuates age-related decrements in cognitive, anxiety, and depressive behavior of male rats
    • Frye C.A., Edinger K.L., Lephart E.D., Walf A.A. 3alpha-Androstanediol, but not testosterone, attenuates age-related decrements in cognitive, anxiety, and depressive behavior of male rats. Front. Aging Neurosci. 2010, 2:15.
    • (2010) Front. Aging Neurosci. , vol.2 , pp. 15
    • Frye, C.A.1    Edinger, K.L.2    Lephart, E.D.3    Walf, A.A.4
  • 54
    • 67349158251 scopus 로고    scopus 로고
    • Progesterone reduces depression-like behavior in a murine model of Alzheimer's disease
    • Frye C.A., Walf A.A. Progesterone reduces depression-like behavior in a murine model of Alzheimer's disease. Age 2009, 31:143-153.
    • (2009) Age , vol.31 , pp. 143-153
    • Frye, C.A.1    Walf, A.A.2
  • 55
    • 84892892196 scopus 로고    scopus 로고
    • The role of allopregnanolone in depression and anxiety
    • Schule C., Nothdurfter C., Rupprecht R. The role of allopregnanolone in depression and anxiety. Prog. Neurobiol. 2014, 113:79-87.
    • (2014) Prog. Neurobiol. , vol.113 , pp. 79-87
    • Schule, C.1    Nothdurfter, C.2    Rupprecht, R.3
  • 57
    • 84891784115 scopus 로고    scopus 로고
    • Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability
    • Carver C.M., Reddy D.S. Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability. Psychopharmacology (Berl) 2013, 230:151-188.
    • (2013) Psychopharmacology (Berl) , vol.230 , pp. 151-188
    • Carver, C.M.1    Reddy, D.S.2
  • 58
  • 59
    • 84903371571 scopus 로고    scopus 로고
    • Dehydroepiandrosterone sulfate and cognition in midlife, post-menopausal women
    • Chua C.K., Henderson V.W., Dennerstein L., Ames D., Szoeke C. Dehydroepiandrosterone sulfate and cognition in midlife, post-menopausal women. Neurobiol. Aging 2014, 35:1654-1655.
    • (2014) Neurobiol. Aging , vol.35 , pp. 1654-1655
    • Chua, C.K.1    Henderson, V.W.2    Dennerstein, L.3    Ames, D.4    Szoeke, C.5
  • 60
    • 33646759950 scopus 로고    scopus 로고
    • Treatment with dehydroepiandrosterone (DHEA) stimulates oxidative energy metabolism in the cerebral mitochondria. A comparative study of effects in old and young adult rats
    • Patel M.A., Katyare S.S. Treatment with dehydroepiandrosterone (DHEA) stimulates oxidative energy metabolism in the cerebral mitochondria. A comparative study of effects in old and young adult rats. Neurosci. Lett. 2006, 402:131-136.
    • (2006) Neurosci. Lett. , vol.402 , pp. 131-136
    • Patel, M.A.1    Katyare, S.S.2
  • 62
    • 35148853175 scopus 로고    scopus 로고
    • Estrogen suppresses brain mitochondrial oxidative stress in female and male rats
    • Razmara A., Duckles S.P., Krause D.N., Procaccio V. Estrogen suppresses brain mitochondrial oxidative stress in female and male rats. Brain Res. 2007, 1176:71-81.
    • (2007) Brain Res. , vol.1176 , pp. 71-81
    • Razmara, A.1    Duckles, S.P.2    Krause, D.N.3    Procaccio, V.4
  • 63
    • 77956178214 scopus 로고    scopus 로고
    • Menopause and mitochondria: windows into estrogen effects on Alzheimer's disease risk and therapy
    • Henderson V.W., Brinton R.D. Menopause and mitochondria: windows into estrogen effects on Alzheimer's disease risk and therapy. Prog. Brain Res. 2010, 182:77-96.
    • (2010) Prog. Brain Res. , vol.182 , pp. 77-96
    • Henderson, V.W.1    Brinton, R.D.2
  • 64
    • 34648834538 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons
    • Reddy P.H. Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons. Antioxid. Redox Signal. 2007, 9:1647-1658.
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 1647-1658
    • Reddy, P.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.