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Volumn 8, Issue 11, 2013, Pages

Neurosteroid 3α-androstanediol efficiently counteracts paclitaxel-induced peripheral neuropathy and painful symptoms

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANEDIOL; ANTINEOPLASTIC AGENT; NEUROPROTECTIVE AGENT; PACLITAXEL;

EID: 84894173275     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080915     Document Type: Article
Times cited : (21)

References (78)
  • 1
    • 79955439425 scopus 로고    scopus 로고
    • Chemotherapy-induced peripheral neuropathies: From clinical relevance to preclinical evidence
    • doi:10.1517/14740338.2011.543417. PubMed: 21210753
    • Balayssac D, Ferrier J, Descoeur J, Ling B, Pezet D, Eschalier A, Authier N (2011) Chemotherapy-induced peripheral neuropathies: from clinical relevance to preclinical evidence. Expert Opin Drug Saf 10: 407-417. doi:10.1517/14740338. 2011.543417. PubMed: 21210753.
    • (2011) Expert Opin Drug Saf , vol.10 , pp. 407-417
    • Balayssac, D.1    Ferrier, J.2    Descoeur, J.3    Ling, B.4    Pezet, D.5    Eschalier, A.6    Authier, N.7
  • 2
    • 0036158822 scopus 로고    scopus 로고
    • Chemotherapy-induced peripheral neuropathy
    • Quasthoff S, Hartung HP (2002) Chemotherapy-induced peripheral neuropathy. J Neurol 249: 9-17. doi:10.1007/PL00007853. PubMed: 11954874. (Pubitemid 34119018)
    • (2002) Journal of Neurology , vol.249 , Issue.1 , pp. 9-17
    • Quasthoff, S.1    Hartung, H.P.2
  • 4
    • 1842735565 scopus 로고    scopus 로고
    • Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients
    • DOI 10.1016/j.pain.2004.01.021, PII S0304395904000533
    • Dougherty PM, Cata JP, Cordella JV, Burton A, Weng HR (2004) Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients. Pain 109: 132-142. doi:10.1016/j.pain.2004.01.021. PubMed: 15082135. (Pubitemid 38479779)
    • (2004) Pain , vol.109 , Issue.1-2 , pp. 132-142
    • Dougherty, P.M.1    Cata, J.P.2    Cordella, J.V.3    Burton, A.4    Weng, H.-R.5
  • 5
    • 0041621727 scopus 로고    scopus 로고
    • Neurotoxic complications of chemotherapy in patients with cancer: Clinical signs and optimal management
    • DOI 10.2165/00003495-200363150-00003
    • Verstappen CC, Heimans JJ, Hoekman K, Postma TJ (2003) Neurotoxic complications of chemotherapy in patients with cancer: clinical signs and optimal management. Drugs 63: 1549-1563. doi: 10.2165/00003495-200363150-00003. PubMed: 12887262. (Pubitemid 36976138)
    • (2003) Drugs , vol.63 , Issue.15 , pp. 1549-1563
    • Verstappen, C.C.P.1    Heimans, J.J.2    Hoekman, K.3    Postma, T.J.4
  • 6
    • 0033927620 scopus 로고    scopus 로고
    • Paclitaxel induces apoptosis in AIDS-related Kaposi's sarcoma cells
    • Cai J, Zheng T, Masood R, Smith DL, Hinton DR, Kim CN, Fang G, Bhalla K, Gill PS (2000) Paclitaxel Induces Apoptosis in AIDS-Related Kaposi's Sarcoma Cells. Sarcoma 4: 37-45. doi:10.1155/S1357714X00000074. PubMed: 18521433. (Pubitemid 30480280)
    • (2000) Sarcoma , vol.4 , Issue.1-2 , pp. 37-45
    • Cai, J.1    Zheng, T.2    Masood, R.3    Smith, D.L.4    Hinton, D.R.5    Kim, C.N.6    Fang, G.7    Bhalla, K.8    Gill, P.S.9
  • 7
    • 80155159962 scopus 로고    scopus 로고
    • Bevacizumab: A review of its use in combination with paclitaxel or capecitabine as first-line therapy for HER2-negative metastatic breast cancer
    • doi: 10.2165/11207720-000000000-00000. PubMed: 22035518
    • Croom KF, Dhillon S (2011) Bevacizumab: a review of its use in combination with paclitaxel or capecitabine as first-line therapy for HER2-negative metastatic breast cancer. Drugs 71: 2213-2229. doi: 10.2165/11207720-000000000-00000. PubMed: 22035518.
    • (2011) Drugs , vol.71 , pp. 2213-2229
    • Croom, K.F.1    Dhillon, S.2
  • 9
    • 84860400947 scopus 로고    scopus 로고
    • Src family kinases and paclitaxel sensitivity
    • doi:10.4161/cbt.12.4.16430. PubMed: 21646863
    • Le XF, Bast RC Jr. (2011) Src family kinases and paclitaxel sensitivity. Cancer Biol Ther 12: 260-269. doi:10.4161/cbt.12.4.16430. PubMed: 21646863.
    • (2011) Cancer Biol Ther , vol.12 , pp. 260-269
    • Le, X.F.1    Bast Jr., R.C.2
  • 10
    • 72449143090 scopus 로고    scopus 로고
    • Paclitaxel in cancer treatment: Perspectives and prospects of its delivery challenges
    • doi:10.1615/CritRevTherDrugCarrierSyst.v26.i4.10. PubMed: 20001890
    • Singh S, Dash AK (2009) Paclitaxel in cancer treatment: perspectives and prospects of its delivery challenges. Crit Rev Ther Drug Carrier Syst 26: 333-372. doi:10.1615/CritRevTherDrugCarrierSyst.v26.i4.10. PubMed: 20001890.
    • (2009) Crit Rev Ther Drug Carrier Syst , vol.26 , pp. 333-372
    • Singh, S.1    Dash, A.K.2
  • 11
    • 0035689892 scopus 로고    scopus 로고
    • Paclitaxel: A pharmacoeconomic review of its use in the treatment of ovarian cancer
    • Young M, Plosker GL (2001) Paclitaxel: a pharmacoeconomic review of its use in the treatment of ovarian cancer. Pharmacoeconomics 19: 1227-1259. doi:10.2165/00019053-200119120-00005. PubMed: 11772158. (Pubitemid 34074786)
    • (2001) PharmacoEconomics , vol.19 , Issue.12 , pp. 1227-1259
    • Young, M.1    Plosker, G.L.2
  • 12
    • 0028901936 scopus 로고
    • Peripheral neurotoxicity of taxol in patients previously treated with cisplatin
    • doi: 10.1002/1097-0142(19950301)75:5. PubMed: 7850713
    • Cavaletti G, Bogliun G, Marzorati L, Zincone A, Marzola M, Colombo N, Tredici G (1995) Peripheral neurotoxicity of taxol in patients previously treated with cisplatin. Cancer 75: 1141-1150. doi: 10.1002/1097-0142(19950301) 75:5. PubMed: 7850713.
    • (1995) Cancer , vol.75 , pp. 1141-1150
    • Cavaletti, G.1    Bogliun, G.2    Marzorati, L.3    Zincone, A.4    Marzola, M.5    Colombo, N.6    Tredici, G.7
  • 13
    • 0028270476 scopus 로고
    • Peripheral neuropathy from taxol and cisplatin combination chemotherapy: Clinical and electrophysiological studies
    • Chaudhry V, Rowinsky EK, Sartorius SE, Donehower RC, Cornblath DR (1994) Peripheral neuropathy from taxol and cisplatin combination chemotherapy: clinical and electrophysiological studies. Ann Neurol 35: 304-311. doi:10.1002/ana.410350310. PubMed: 7907208. (Pubitemid 24089653)
    • (1994) Annals of Neurology , vol.35 , Issue.3 , pp. 304-311
    • Chaudhry, V.1    Rowinsky, E.K.2    Sartorius, S.E.3    Donehower, R.C.4    Cornblath, D.R.5
  • 14
    • 0030839691 scopus 로고    scopus 로고
    • Prospective study of paclitaxel-induced peripheral neuropathy with quantitative sensory testing
    • DOI 10.1023/A:1005805907311
    • Forsyth PA, Balmaceda C, Peterson K, Seidman AD, Brasher P, DeAngelis LM (1997) Prospective study of paclitaxel-induced peripheral neuropathy with quantitative sensory testing. J Neuro Oncol 35: 47-53. doi:10.1023/A: 1005805907311. PubMed: 9266440. (Pubitemid 27361845)
    • (1997) Journal of Neuro-Oncology , vol.35 , Issue.1 , pp. 47-53
    • Forsyth, P.A.1    Balmaceda, C.2    Peterson, K.3    Seidman, A.D.4    Brasher, P.5    DeAngelis, L.M.6
  • 15
    • 0030913598 scopus 로고    scopus 로고
    • Phase I dose escalation of paclitaxel in patients with advanced ovarian cancer receiving cisplatin: Rapid development of neurotoxicity is dose- limiting
    • Gordon AN, Stringer CA, Matthews CM, Willis DL, Nemunaitis J (1997) Phase I dose escalation of paclitaxel in patients with advanced ovarian cancer receiving cisplatin: rapid development of neurotoxicity is doselimiting. J Clin Oncol 15: 1965-1973. PubMed: 9164208. (Pubitemid 27209527)
    • (1997) Journal of Clinical Oncology , vol.15 , Issue.5 , pp. 1965-1973
    • Gordon, A.N.1    Stringer, C.A.2    Matthews, C.M.3    Willis, D.L.4    Nemunaitis, J.5
  • 16
    • 0035214661 scopus 로고    scopus 로고
    • A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel
    • DOI 10.1016/S0304-3959(01)00363-3, PII S0304395901003633
    • Polomano RC, Mannes AJ, Clark US, Bennett GJ (2001) A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel. Pain 94: 293-304. doi:10.1016/S0304-3959(01)00363-3. PubMed: 11731066. (Pubitemid 33145399)
    • (2001) Pain , vol.94 , Issue.3 , pp. 293-304
    • Polomano, R.C.1    Mannes, A.J.2    Clark, U.S.3    Bennett, G.J.4
  • 18
    • 0030910759 scopus 로고    scopus 로고
    • Progression of paclitaxel-induced neuropathy following discontinuation of treatment
    • DOI 10.1002/(SICI)1097-4598(199706)20:6<750::AID-MU
    • van den Bent MJ, van Raaij-van den Aarssen VJ, Verweij J, Doorn PA, Smitt Sillevis (1997) Progression of paclitaxel-induced neuropathy following discontinuation of treatment. Muscle Nerve 20: 750-752. doi: 10.1002/(SICI)1097-4598(199706)20:6. PubMed: 9149085. (Pubitemid 27197731)
    • (1997) Muscle and Nerve , vol.20 , Issue.6 , pp. 750-752
    • Van Den, B.M.J.1    Van Raaij-Van, D.A.V.J.M.2    Verweij, J.3    Doorn, P.A.V.4    Smitt, P.A.E.S.5
  • 19
    • 18844420343 scopus 로고    scopus 로고
    • Clinical activity of venlafaxine and topiramate against oxaliplatin-induced disabling permanent neuropathy
    • DOI 10.1097/00001813-200506000-00015
    • Durand JP, Alexandre J, Guillevin L, Goldwasser F (2005) Clinical activity of venlafaxine and topiramate against oxaliplatin-induced disabling permanent neuropathy. Anti Cancer Drugs 16: 587-591. doi: 10.1097/00001813- 200506000-00015. PubMed: 15846125. (Pubitemid 40685744)
    • (2005) Anti-Cancer Drugs , vol.16 , Issue.5 , pp. 587-591
    • Durand, J.-P.1    Alexandre, J.2    Guillevin, L.3    Goldwasser, F.4
  • 20
    • 3042523914 scopus 로고    scopus 로고
    • Prevention of oxaliplatin-related neurotoxicity by calcium and magnesium infusions: A retrospective study of 161 patients receiving oxaliplatin combined with 5-fluorouracil and leucovorin for advanced colorectal cancer
    • DOI 10.1158/1078-0432.CCR-03-0666
    • Gamelin L, Boisdron-Celle M, Delva R, Guérin-Meyer V, Ifrah N, Morel A, Gamelin E (2004) Prevention of oxaliplatin-related neurotoxicity by calcium and magnesium infusions: a retrospective study of 161 patients receiving oxaliplatin combined with 5-Fluorouracil and leucovorin for advanced colorectal cancer. Clin Cancer Res 10: 4055-4061. doi: 10.1158/1078-0432.CCR-03-0666. PubMed: 15217938. (Pubitemid 38812481)
    • (2004) Clinical Cancer Research , vol.10 , Issue.12 I , pp. 4055-4061
    • Gamelin, L.1    Boisdron-Celle, M.2    Delva, R.3    Guerin-Meyer, V.4    Ifrah, N.5    Morel, A.6    Gamelin, E.7
  • 21
    • 0030275439 scopus 로고    scopus 로고
    • Venlafaxine hydrochloride (Effexor) relieves thermal hyperalgesia in rats with an experimental mononeuropathy
    • DOI 10.1016/S0304-3959(96)03223-X, PII S030439599603223X
    • Lang E, Hord AH, Denson D (1996) Venlafaxine hydrochloride (Effexor) relieves thermal hyperalgesia in rats with an experimental mononeuropathy. Pain 68: 151-155. doi:10.1016/S0304-3959(96)03223-X. PubMed: 9252010. (Pubitemid 126407767)
    • (1996) Pain , vol.68 , Issue.1 , pp. 151-155
    • Lang, E.1    Hord, A.H.2    Denson, D.3
  • 22
    • 33847796722 scopus 로고    scopus 로고
    • Behavioral and pharmacological description of oxaliplatin-induced painful neuropathy in rat
    • DOI 10.1016/j.pain.2006.09.016, PII S0304395906004921
    • Ling B, Authier N, Balayssac D, Eschalier A, Coudore F (2007) Behavioral and pharmacological description of oxaliplatin-induced painful neuropathy in rat. Pain 128: 225-234. doi:10.1016/j.pain.2006.09.016. PubMed: 17084975. (Pubitemid 46389544)
    • (2007) Pain , vol.128 , Issue.3 , pp. 225-234
    • Ling, B.1    Authier, N.2    Balayssac, D.3    Eschalier, A.4    Coudore, F.5
  • 23
    • 0038359357 scopus 로고    scopus 로고
    • Evidence for a monoamine mediated, opioid-independent, antihyperalgesic effect of venlafaxine, a non-tricyclic antidepressant, in a neurogenic pain model in rats
    • DOI 10.1016/S0304-3959(03)00168-4
    • Marchand F, Alloui A, Chapuy E, Jourdan D, Pelissier T, Ardid D, Hernandez A, Eschalier A (2003) Evidence for a monoamine mediated, opioid-independent, antihyperalgesic effect of venlafaxine, a non-tricyclic antidepressant, in a neurogenic pain model in rats. Pain 103: 229-235. doi:10.1016/S0304-3959(03)00168-4. PubMed: 12791429. (Pubitemid 36638812)
    • (2003) Pain , vol.103 , Issue.3 , pp. 229-235
    • Marchand, F.1    Alloui, A.2    Chapuy, E.3    Jourdan, D.4    Pelissier, T.5    Ardid, D.6    Hernandez, A.7    Eschalier, A.8
  • 24
    • 77956784645 scopus 로고    scopus 로고
    • Cellular and functional evidence for a protective action of neurosteroids against vincristine chemotherapy-induced painful neuropathy
    • doi:10.1007/s00018-010-0372-0. PubMed: 20431905
    • Meyer L, Patte-Mensah C, Taleb O, Mensah-Nyagan AG (2010) Cellular and functional evidence for a protective action of neurosteroids against vincristine chemotherapy-induced painful neuropathy. Cell Mol Life Sci 67: 3017-3034. doi:10.1007/s00018-010-0372-0. PubMed: 20431905.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 3017-3034
    • Meyer, L.1    Patte-Mensah, C.2    Taleb, O.3    Mensah-Nyagan, A.G.4
  • 25
    • 78650415465 scopus 로고    scopus 로고
    • Allopregnanolone prevents and suppresses oxaliplatin-evoked painful neuropathy: Multi-parametric assessment and direct evidence
    • doi:10.1016/j.pain.2010.10.015. PubMed: 21071147
    • Meyer L, Patte-Mensah C, Taleb O, Mensah-Nyagan AG (2011) Allopregnanolone prevents and suppresses oxaliplatin-evoked painful neuropathy: multi-parametric assessment and direct evidence. Pain 152: 170-181. doi:10.1016/j.pain.2010.10.015. PubMed: 21071147.
    • (2011) Pain , vol.152 , pp. 170-181
    • Meyer, L.1    Patte-Mensah, C.2    Taleb, O.3    Mensah-Nyagan, A.G.4
  • 26
    • 21744447595 scopus 로고    scopus 로고
    • A receptor
    • DOI 10.1038/nrn1703
    • Belelli D, Lambert JJ (2005) Neurosteroids: endogenous regulators of the GABA(A) receptor. Nat Rev Neurosci 6: 565-575. doi:10.1038/nrn1703. PubMed: 15959466. (Pubitemid 40942823)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.7 , pp. 565-575
    • Belelli, D.1    Lambert, J.J.2
  • 27
    • 0030069886 scopus 로고    scopus 로고
    • Chronic anabolic-androgenic steroid treatment affects brain GABA(A) receptor-gated chloride ion transport
    • doi: 10.1016/0024-3205(95)02326-7. PubMed: 8632710
    • Bitran D, Hilvers RJ, Frye CA, Erskine MS (1996) Chronic anabolic-androgenic steroid treatment affects brain GABA(A) receptor-gated chloride ion transport. Life Sci 58: 573-583. doi: 10.1016/0024-3205(95)02326-7. PubMed: 8632710.
    • (1996) Life Sci , vol.58 , pp. 573-583
    • Bitran, D.1    Hilvers, R.J.2    Frye, C.A.3    Erskine, M.S.4
  • 28
    • 0030245598 scopus 로고    scopus 로고
    • Behavioral effects of 3alpha-androstanediol II: Hypothalamic and preoptic area actions via a GABAergic mechanism
    • DOI 10.1016/S0166-4328(96)00005-8
    • Frye CA, Duncan JE, Basham M, Erskine MS (1996) Behavioral effects of 3 alpha-androstanediol. II: Hypothalamic and preoptic area actions via a GABAergic mechanism. Behav Brain Res 79: 119-130. doi: 10.1016/0166-4328(96)00005-8. PubMed: 8883823. (Pubitemid 26308932)
    • (1996) Behavioural Brain Research , vol.79 , Issue.1-2 , pp. 119-130
    • Frye, C.A.1    Duncan, J.E.2    Basham, M.3    Erskine, M.S.4
  • 29
    • 0034897446 scopus 로고    scopus 로고
    • The testosterone metabolite and neurosteroid 3alpha-androstanediol may mediate the effects of testosterone on conditioned place preference
    • DOI 10.1016/S0306-4530(01)00027-0, PII S0306453001000270
    • Frye CA, Park D, Tanaka M, Rosellini R, Svare B (2001) The testosterone metabolite and neurosteroid 3alpha-androstanediol may mediate the effects of testosterone on conditioned place preference. Psychoneuroendocrinol 26: 731-750. doi:10.1016/S0306-4530(01)00027-0. PubMed: 1174408411500254. (Pubitemid 32738997)
    • (2001) Psychoneuroendocrinology , vol.26 , Issue.7 , pp. 731-750
    • Frye, C.A.1    Park, D.2    Tanaka, M.3    Rosellini, R.4    Svare, B.5
  • 30
    • 33751314737 scopus 로고    scopus 로고
    • A receptors through two discrete transmembrane sites
    • DOI 10.1038/nature05324, PII NATURE05324
    • Hosie AM, Wilkins ME, da Silva HM, Smart TG (2006) Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites. Nature 444: 486-489. doi:10.1038/nature05324. PubMed: 17108970. (Pubitemid 44809065)
    • (2006) Nature , vol.444 , Issue.7118 , pp. 486-489
    • Hosie, A.M.1    Wilkins, M.E.2    Da, S.H.M.A.3    Smart, T.G.4
  • 31
    • 38349187871 scopus 로고    scopus 로고
    • Mass spectrometric assay and physiological-pharmacological activity of androgenic neurosteroids
    • doi:10.1016/j.neuint.2007.05.019. PubMed: 17624627
    • Reddy DS (2008) Mass spectrometric assay and physiological- pharmacological activity of androgenic neurosteroids. Neurochem Int 52: 541-553. doi:10.1016/j.neuint.2007.05.019. PubMed: 17624627.
    • (2008) Neurochem Int , vol.52 , pp. 541-553
    • Reddy, D.S.1
  • 32
    • 33847150143 scopus 로고    scopus 로고
    • Self-administration of 3alpha-androstanediol increases locomotion and analgesia and decreases aggressive behavior of male hamsters
    • DOI 10.1016/j.pbb.2006.05.025, PII S0091305706001705, Adolescents, drug abuse and mental disorders
    • Frye CA, Babson A, Walf AA (2007) Self-administration of 3alpha-androstanediol increases locomotion and analgesia and decreases aggressive behavior of male hamsters. Pharmacol Biochem Behav 86: 415-421. doi:10.1016/j.pbb.2006.05.025. PubMed: 16828856. (Pubitemid 46282039)
    • (2007) Pharmacology Biochemistry and Behavior , vol.86 , Issue.2 , pp. 415-421
    • Frye, C.A.1    Babson, A.2    Walf, A.A.3
  • 33
    • 3142604665 scopus 로고    scopus 로고
    • Androgens in the hippocampus can alter, and be altered by, ictal activity
    • DOI 10.1016/j.pbb.2004.04.020, PII S0091305704001431
    • Rhodes ME, Frye CA (2004) Androgens in the hippocampus can alter, and be altered by, ictal activity. Pharmacol Biochem Behav 78: 483-493. doi:10.1016/j.pbb.2004.04.020. PubMed: 15251257. (Pubitemid 38901016)
    • (2004) Pharmacology Biochemistry and Behavior , vol.78 , Issue.3 , pp. 483-493
    • Rhodes, M.E.1    Frye, C.A.2
  • 34
    • 3142619945 scopus 로고    scopus 로고
    • Testosterone's analgesic, anxiolytic, and cognitive-enhancing effects may be due in part to actions of its 5alpha-reduced metabolites in the hippocampus
    • DOI 10.1037/0735-7044.118.6.1352
    • Edinger KL, Frye CA (2004) Testosterone's analgesic, anxiolytic, and cognitive-enhancing effects may be due in part to actions of its 5alpha-reduced metabolites in the hippocampus. Behav Neurosci 118: 1352-1364. doi:10.1037/0735-7044.118.6.1352. PubMed: 15598144. (Pubitemid 39578482)
    • (2004) Behavioral Neuroscience , vol.118 , Issue.6 , pp. 1352-1364
    • Edinger, K.L.1    Frye, C.A.2
  • 35
    • 0032731191 scopus 로고    scopus 로고
    • The amygdala mediates the anxiolytic-like effect of the neurosteroid allopregnanolone in rat
    • DOI 10.1016/S0166-4328(99)00101-1, PII S0166432899001011
    • Akwa Y, Purdy RH, Koob GF, Britton KT (1999) The amygdala mediates the anxiolytic-like effect of the neurosteroid allopregnanolone in rat. Behav Brain Res 106: 119-125. doi:10.1016/S0166-4328(99)00101-1. PubMed: 10595427. (Pubitemid 29528492)
    • (1999) Behavioural Brain Research , vol.106 , Issue.1-2 , pp. 119-125
    • Akwa, Y.1    Purdy, R.H.2    Koob, G.F.3    Britton, K.T.4
  • 36
    • 0742272125 scopus 로고    scopus 로고
    • Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo
    • DOI 10.1111/j.1365-2826.2004.01121.x
    • Ciriza I, Azcoitia I, Garcia-Segura LM (2004) Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo. J Neuroendocrinol 16: 58-63. doi:10.1111/j.1365-2826.2004.01121.x. PubMed: 14962077. (Pubitemid 38159394)
    • (2004) Journal of Neuroendocrinology , vol.16 , Issue.1 , pp. 58-63
    • Ciriza, I.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 37
    • 33747099290 scopus 로고    scopus 로고
    • Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective
    • DOI 10.1002/neu.20293
    • Ciriza I, Carrero P, Frye CA, Garcia-Segura LM (2006) Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective. J Neurobiol 66: 916-928. doi: 10.1002/neu.20293. PubMed: 16758493. (Pubitemid 44222653)
    • (2006) Journal of Neurobiology , vol.66 , Issue.9 , pp. 916-928
    • Ciriza, I.1    Carrero, P.2    Frye, C.A.3    Garcia-Segura, L.M.4
  • 38
    • 3142774112 scopus 로고    scopus 로고
    • Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone
    • DOI 10.1038/nm1073
    • Griffin LD, Gong W, Verot L, Mellon SH (2004) Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone. Nat Med 10: 704-711. doi:10.1038/nm1073. PubMed: 15208706. (Pubitemid 38937635)
    • (2004) Nature Medicine , vol.10 , Issue.7 , pp. 704-711
    • Griffin, L.D.1    Gong, W.2    Verot, L.3    Mellon, S.H.4
  • 39
    • 40849126968 scopus 로고    scopus 로고
    • The biological activity of 3alpha-hydroxysteroid oxido-reductase in the spinal cord regulates thermal and mechanical pain thresholds after sciatic nerve injury
    • DOI 10.1016/j.nbd.2007.12.001, PII S0969996107002689
    • Meyer L, Venard C, Schaeffer V, Patte-Mensah C, Mensah-Nyagan AG (2008) The biological activity of 3alpha-hydroxysteroid oxido-reductase in the spinal cord regulates thermal and mechanical pain thresholds after sciatic nerve injury. Neurobiol Dis 30: 30-41. doi:10.1016/j.nbd.2007.12.001. PubMed: 18291663. (Pubitemid 351391981)
    • (2008) Neurobiology of Disease , vol.30 , Issue.1 , pp. 30-41
    • Meyer, L.1    Venard, C.2    Schaeffer, V.3    Patte-Mensah, C.4    Mensah-Nyagan, A.G.5
  • 42
    • 77950868172 scopus 로고    scopus 로고
    • Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease
    • doi:10.1073/pnas.1001422107. PubMed: 20231471
    • Wang JM, Singh C, Liu L, Irwin RW, Chen S, Chung EJ, Thompson RF, Brinton RD (2010) Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 107: 6498-6503. doi:10.1073/pnas.1001422107. PubMed: 20231471.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 6498-6503
    • Wang, J.M.1    Singh, C.2    Liu, L.3    Irwin, R.W.4    Chen, S.5    Chung, E.J.6    Thompson, R.F.7    Brinton, R.D.8
  • 43
    • 0037370361 scopus 로고    scopus 로고
    • Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination
    • DOI 10.1038/ng1095
    • Lappe-Siefke C, Goebbels S, Gravel M, Nicksch E, Lee J, Braun PE, Griffiths IR, Nave KA (2003) Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nat Genet 33: 366-374. doi:10.1038/ng1095. PubMed: 12590258. (Pubitemid 36278853)
    • (2003) Nature Genetics , vol.33 , Issue.3 , pp. 366-374
    • Lappe-Siefke, C.1    Goebbels, S.2    Gravel, M.3    Nicksch, E.4    Lee, J.5    Braun, P.E.6    Griffiths, I.R.7    Navel, K.-A.8
  • 44
    • 0026699427 scopus 로고
    • Regulation of 2',3'-cyclic nucleotide phosphodiesterase gene expression in experimental peripheral neuropathies
    • doi:10.1016/0169-328X(92)90149-6. PubMed: 1279349
    • LeBlanc AC, Pringle J, Lemieux J, Poduslo JF, Mezei C (1992) Regulation of 2',3'-cyclic nucleotide phosphodiesterase gene expression in experimental peripheral neuropathies. Brain Res. Mol Brain Res 15: 40-46. doi:10.1016/0169-328X(92)90149-6. PubMed: 1279349.
    • (1992) Brain Res. Mol Brain Res , vol.15 , pp. 40-46
    • LeBlanc, A.C.1    Pringle, J.2    Lemieux, J.3    Poduslo, J.F.4    Mezei, C.5
  • 46
    • 40449088635 scopus 로고    scopus 로고
    • Neuroactive steroids: State of the art and new perspectives
    • doi:10.1007/s00018-007-7403-5. PubMed: 18038216
    • Melcangi RC, Garcia-Segura LM, Mensah-Nyagan AG (2008) Neuroactive steroids: state of the art and new perspectives. Cell Mol Life Sci 65: 777-797. doi:10.1007/s00018-007-7403-5. PubMed: 18038216.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 777-797
    • Melcangi, R.C.1    Garcia-Segura, L.M.2    Mensah-Nyagan, A.G.3
  • 47
    • 0032956181 scopus 로고    scopus 로고
    • Neurosteroids: Expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system
    • Mensah-Nyagan AG, Do-Rego JL, Beaujean D, Luu-The V, Pelletier G, Vaudry H (1999) Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system. Pharmacol Rev 51: 63-81. PubMed: 10049998. (Pubitemid 29113866)
    • (1999) Pharmacological Reviews , vol.51 , Issue.1 , pp. 63-81
    • Mensah-Nyagan, A.G.1    Do-Rego, J.-L.2    Beaujean, D.3    Luu-The, V.4    Pelletier, G.5    Vaudry, H.6
  • 48
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • doi: 10.1016/0304-3959(83)90201-4. PubMed: 6877845
    • Zimmermann M (1983) Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16: 109-110. doi: 10.1016/0304-3959(83)90201-4. PubMed: 6877845.
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1
  • 49
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • doi:10.1016/0304-3959(88)90026-7. PubMed: 3340425
    • Hargreaves K, Dubner R, Brown F, Flores C, Joris J (1988) A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32: 77-88. doi:10.1016/0304-3959(88)90026-7. PubMed: 3340425.
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 51
    • 0022803115 scopus 로고
    • Reactivity of a panel of neurofilament antibodies on phosphorylated and dephosphorylated neurofilaments
    • PubMed: 3539605
    • Shaw G, Osborn M, Weber K (1986) Reactivity of a panel of neurofilament antibodies on phosphorylated and dephosphorylated neurofilaments. Eur J Cell Biol 42: 1-9. PubMed: 3539605.
    • (1986) Eur J Cell Biol , vol.42 , pp. 1-9
    • Shaw, G.1    Osborn, M.2    Weber, K.3
  • 52
    • 33748430474 scopus 로고    scopus 로고
    • Paclitaxel- and vincristine-evoked painful peripheral neuropathies: Loss of epidermal innervation and activation of Langerhans cells
    • DOI 10.1016/j.expneurol.2006.05.007, PII S0014488606002937
    • Siau C, Xiao W, Bennett GJ (2006) Paclitaxel- and vincristine-evoked painful peripheral neuropathies: loss of epidermal innervation and activation of Langerhans cells. Exp Neurol 201: 507-514. doi:10.1016/j.expneurol.2006.05.007. PubMed: 16797537. (Pubitemid 44344243)
    • (2006) Experimental Neurology , vol.201 , Issue.2 , pp. 507-514
    • Siau, C.1    Xiao, W.2    Bennett, G.J.3
  • 53
    • 0024600269 scopus 로고
    • 2',3'-cyclic nucleotide 3'-phosphodiesterase, an oligodendrocyte-Schwann cell and myelin-associated enzyme of the nervous system
    • PubMed: 2537684
    • Sprinkle TJ (1989) 2',3'-cyclic nucleotide 3'-phosphodiesterase, an oligodendrocyte-Schwann cell and myelin-associated enzyme of the nervous system. Crit Rev Neurobiol 4: 235-301. PubMed: 2537684.
    • (1989) Crit Rev Neurobiol , vol.4 , pp. 235-301
    • Sprinkle, T.J.1
  • 54
    • 0021954440 scopus 로고
    • Localization of 2',3'-cyclic nucleotide 3'-phosphodiesterase on cultured Schwann cells
    • DOI 10.1016/0006-8993(85)90316-6
    • Yoshino JE, Dinneen MP, Sprinkle TJ, DeVries GH (1985) Localization of 2',3'-cyclic nucleotide 3'-phosphodiesterase on cultured Schwann cells. Brain Res 325: 199-203. doi:10.1016/0006-8993(85)90316-6. PubMed: 2983827. (Pubitemid 15134882)
    • (1985) Brain Research , vol.325 , Issue.1-2 , pp. 199-203
    • Yoshino, J.E.1    Dinneen, M.P.2    Sprinkle, T.J.3    DeVries, G.H.4
  • 55
    • 0029972544 scopus 로고    scopus 로고
    • Neuronal intermediate filaments
    • Lee MK, Cleveland DW (1996) Neuronal intermediate filaments. Annu Rev Neurosci 19: 187-217. doi:10.1146/annurev.ne.19.030196.001155. PubMed: 8833441. (Pubitemid 26080827)
    • (1996) Annual Review of Neuroscience , vol.19 , pp. 187-217
    • Lee, M.K.1    Cleveland, D.W.2
  • 56
    • 64549093289 scopus 로고    scopus 로고
    • Depression-like behavior of aged male and female mice is ameliorated with administration of testosterone or its metabolites
    • doi:10.1016/j.physbeh.2009.02.022. PubMed: 19254734
    • Frye CA, Walf AA (2009) Depression-like behavior of aged male and female mice is ameliorated with administration of testosterone or its metabolites. Physiol Behav 97: 266-269. doi:10.1016/j.physbeh.2009.02.022. PubMed: 19254734.
    • (2009) Physiol Behav , vol.97 , pp. 266-269
    • Frye, C.A.1    Walf, A.A.2
  • 57
    • 78649719759 scopus 로고    scopus 로고
    • 3alpha-androstanediol, but not testosterone, attenuates age-related decrements in cognitive, anxiety, and depressive behavior of male rats
    • PubMed: 20552051
    • Frye CA, Edinger KL, Lephart ED, Walf AA (2010) 3alpha-androstanediol, but not testosterone, attenuates age-related decrements in cognitive, anxiety, and depressive behavior of male rats. Front Aging Neurosci 2: 15. PubMed: 20552051.
    • (2010) Front Aging Neurosci , vol.2 , pp. 15
    • Frye, C.A.1    Edinger, K.L.2    Lephart, E.D.3    Walf, A.A.4
  • 60
    • 0028999006 scopus 로고
    • Experimental peripheral neuropathy induced in adult rats by repeated intraperitoneal administration of taxol
    • doi:10.1006/exnr.1995.1008. PubMed: 7601264
    • Cavaletti G, Tredici G, Braga M, Tazzari S (1995) Experimental peripheral neuropathy induced in adult rats by repeated intraperitoneal administration of taxol. Exp Neurol 133: 64-72. doi:10.1006/exnr.1995.1008. PubMed: 7601264.
    • (1995) Exp Neurol , vol.133 , pp. 64-72
    • Cavaletti, G.1    Tredici, G.2    Braga, M.3    Tazzari, S.4
  • 61
    • 0036771836 scopus 로고    scopus 로고
    • WldS mice are resistant to paclitaxel (taxol) neuropathy
    • doi: 10.1002/ana.10300. PubMed: 12325073
    • Wang MS, Davis AA, Culver DG, Glass JD (2002) WldS mice are resistant to paclitaxel (taxol) neuropathy. Ann Neurol 52: 442-447. doi: 10.1002/ana.10300. PubMed: 12325073.
    • (2002) Ann Neurol , vol.52 , pp. 442-447
    • Wang, M.S.1    Davis, A.A.2    Culver, D.G.3    Glass, J.D.4
  • 63
    • 78651477418 scopus 로고    scopus 로고
    • Intraepidermal nerve fiber loss corresponds to the development of taxol-induced hyperalgesia and can be prevented by treatment with minocycline
    • doi:10.1016/j.pain.2010.10.030. PubMed: 21145656
    • Boyette-Davis J, Xin W, Zhang H, Dougherty PM (2011) Intraepidermal nerve fiber loss corresponds to the development of taxol-induced hyperalgesia and can be prevented by treatment with minocycline. Pain 152: 308-313. doi:10.1016/j.pain.2010.10.030. PubMed: 21145656.
    • (2011) Pain , vol.152 , pp. 308-313
    • Boyette-Davis, J.1    Xin, W.2    Zhang, H.3    Dougherty, P.M.4
  • 64
    • 33846571392 scopus 로고    scopus 로고
    • Dysfunction in Multiple Primary Afferent Fiber Subtypes Revealed By Quantitative Sensory Testing in Patients with Chronic Vincristine-Induced Pain
    • DOI 10.1016/j.jpainsymman.2006.08.006, PII S0885392406006798
    • Dougherty PM, Cata JP, Burton AW, Vu K, Weng HR (2007) Dysfunction in multiple primary afferent fiber subtypes revealed by quantitative sensory testing in patients with chronic vincristine-induced pain. J Pain Symptom Manage 33: 166-179. doi:10.1016/j.jpainsymman.2006.08.006. PubMed: 17280922. (Pubitemid 46186866)
    • (2007) Journal of Pain and Symptom Management , vol.33 , Issue.2 , pp. 166-179
    • Dougherty, P.M.1    Cata, J.P.2    Burton, A.W.3    Vu, K.4    Weng, H.-R.5
  • 65
    • 17344373155 scopus 로고    scopus 로고
    • Nociceptor hyper-responsiveness during vincristine-induced painful peripheral neuropathy in the rat
    • PubMed: 9698336
    • Tanner KD, Reichling DB, Levine JD (1998) Nociceptor hyper-responsiveness during vincristine-induced painful peripheral neuropathy in the rat. J Neurosci 18: 6480-6491. PubMed: 9698336.
    • (1998) J Neurosci , vol.18 , pp. 6480-6491
    • Tanner, K.D.1    Reichling, D.B.2    Levine, J.D.3
  • 67
    • 0034576145 scopus 로고    scopus 로고
    • Electrophysiological properties of axons in mice lacking neurofilament subunit genes: Disparity between conduction velocity and axon diameter in absence of NF-H
    • doi:10.1016/S0006-8993(00)02899-7. PubMed: 11121527
    • Kriz J, Zhu Q, Julien JP, Padjen AL (2000) Electrophysiological properties of axons in mice lacking neurofilament subunit genes: disparity between conduction velocity and axon diameter in absence of NF-H. Brain Res 885: 32-44. doi:10.1016/S0006-8993(00)02899-7. PubMed: 11121527.
    • (2000) Brain Res , vol.885 , pp. 32-44
    • Kriz, J.1    Zhu, Q.2    Julien, J.P.3    Padjen, A.L.4
  • 69
    • 0022353699 scopus 로고
    • Slowing of neurofilament transport and the radial growth of developing nerve fibers
    • Hoffman PN, Griffin JW, Gold BG, Price DL (1985) Slowing of neurofilament transport and the radial growth of developing nerve fibers. J Neurosci 5: 2920-2929. PubMed: 2414416. (Pubitemid 16225492)
    • (1985) Journal of Neuroscience , vol.5 , Issue.11 , pp. 2920-2929
    • Hoffman, P.N.1    Griffin, J.W.2    Gold, B.G.3    Price, D.L.4
  • 70
    • 0021280389 scopus 로고
    • Control of axonal caliber by neurofilament transport
    • Hoffman PN, Griffin JW, Price DL (1984) Control of axonal caliber by neurofilament transport. J Cell Biol 99: 705-714. doi:10.1083/jcb.99.2.705. PubMed: 6204997. (Pubitemid 14065199)
    • (1984) Journal of Cell Biology , vol.99 , Issue.2 , pp. 705-714
    • Hoffman, P.N.1    Griffin, J.W.2    Price, D.L.3
  • 71
    • 0031985487 scopus 로고    scopus 로고
    • 2-terminal kinase/activator protein 1 pathway and inhibition of extracellular signal-regulated kinase are early effects in paclitaxel-mediated apoptosis in human B lymphoblasts
    • Amato SF, Swart JM, Berg M, Wanebo HJ, Mehta SR, Chiles TC (1998) Transient stimulation of the c-Jun-NH2-terminal kinase/activator protein 1 pathway and inhibition of extracellular signal-regulated kinase are early effects in paclitaxel-mediated apoptosis in human B lymphoblasts. Cancer Res 58: 241-247. PubMed: 9443400. (Pubitemid 28047062)
    • (1998) Cancer Research , vol.58 , Issue.2 , pp. 241-247
    • Amato, S.F.1    Swart, J.M.2    Berg, M.3    Wanebo, H.J.4    Mehta, S.R.5    Chiles, T.C.6
  • 72
    • 79960026150 scopus 로고    scopus 로고
    • Deciphering the role of forkhead transcription factors in cancer therapy
    • doi:10.2174/138945011796150299. PubMed: 21443462
    • Yang JY, Hung MC (2011) Deciphering the role of forkhead transcription factors in cancer therapy. Curr Drug Targets 12: 1284-1290. doi:10.2174/ 138945011796150299. PubMed: 21443462.
    • (2011) Curr Drug Targets , vol.12 , pp. 1284-1290
    • Yang, J.Y.1    Hung, M.C.2
  • 73
    • 34548226494 scopus 로고    scopus 로고
    • An evolving cellular pathology occurs in dorsal root ganglia, peripheral nerve and spinal cord following intravenous administration of paclitaxel in the rat
    • DOI 10.1016/j.brainres.2007.06.066, PII S0006899307013728
    • Peters CM, Jimenez-Andrade JM, Kuskowski MA, Ghilardi JR, Mantyh PW (2007) An evolving cellular pathology occurs in dorsal root ganglia, peripheral nerve and spinal cord following intravenous administration of paclitaxel in the rat. Brain Res 1168: 46-59. doi:10.1016/j.brainres.2007.06.066. PubMed: 17698044. (Pubitemid 47320623)
    • (2007) Brain Research , vol.1168 , Issue.1 , pp. 46-59
    • Peters, C.M.1    Jimenez-Andrade, J.M.2    Kuskowski, M.A.3    Ghilardi, J.R.4    Mantyh, P.W.5
  • 74
    • 21144432157 scopus 로고    scopus 로고
    • Substance P inhibits progesterone conversion to neuroactive metabolites in spinal sensory circuit: A potential component of nociception
    • DOI 10.1073/pnas.0502968102
    • Patte-Mensah C, Kibaly C, Mensah-Nyagan AG (2005) Substance P inhibits progesterone conversion to neuroactive metabolites in spinal sensory circuit: a potential component of nociception. Proc Natl Acad Sci U S A 102: 9044-9049. doi:10.1073/pnas.0502968102. PubMed: 15951421. (Pubitemid 40881075)
    • (2005) Proceedings of the National Academy of Sciences of the United States of America , vol.102 , Issue.25 , pp. 9044-9049
    • Patte-Mensah, C.1    Kibaly, C.2    Mensah-Nyagan, A.G.3
  • 75
    • 4344694364 scopus 로고    scopus 로고
    • Anatomical and cellular localization of neuroactive 5alpha/3alpha- reduced steroid-synthesizing enzymes in the spinal cord
    • DOI 10.1002/cne.20251
    • Patte-Mensah C, Penning TM, Mensah-Nyagan AG (2004) Anatomical and cellular localization of neuroactive 5 alpha/3 alpha-reduced steroid-synthesizing enzymes in the spinal cord. J Comp Neurol 477: 286-299. doi:10.1002/cne.20251. PubMed: 15305365. (Pubitemid 39136235)
    • (2004) Journal of Comparative Neurology , vol.477 , Issue.3 , pp. 286-299
    • Patte-Mensah, C.1    Penning, T.M.2    Mensah-Nyagan, A.G.3
  • 76
    • 13844276633 scopus 로고    scopus 로고
    • Testosterone's anti-anxiety and analgesic effects may be due in part to actions of its 5alpha-reduced metabolites in the hippocampus
    • DOI 10.1016/j.psyneuen.2004.11.001
    • Edinger KL, Frye CA (2005) Testosterone's anti-anxiety and analgesic effects may be due in part to actions of its 5alpha-reduced metabolites in the hippocampus. Psychoneuroendocrinol 30: 418-430. doi:10.1016/j.psyneuen.2004.11. 001. PubMed: 15721054. (Pubitemid 40249808)
    • (2005) Psychoneuroendocrinology , vol.30 , Issue.5 , pp. 418-430
    • Edinger, K.L.1    Frye, C.A.2
  • 78
    • 32544454801 scopus 로고    scopus 로고
    • Proliferation and death of oligodendrocytes and myelin proteins are differentially regulated in male and female rodents
    • DOI 10.1523/JNEUROSCI.2219-05.2006
    • Cerghet M, Skoff RP, Bessert D, Zhang Z, Mullins C, Ghandour MS (2006) Proliferation and death of oligodendrocytes and myelin proteins are differentially regulated in male and female rodents. J Neurosci 26: 1439-1447. doi:10.1523/JNEUROSCI.2219-05.2006. PubMed: 16452667. (Pubitemid 43237014)
    • (2006) Journal of Neuroscience , vol.26 , Issue.5 , pp. 1439-1447
    • Cerghet, M.1    Skoff, R.P.2    Bessert, D.3    Zhang, Z.4    Mullins, C.5    Ghandour, M.S.6


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