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Volumn 33, Issue 8, 2012, Pages 1507-1521

Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid

Author keywords

Alzheimer's; Bioenergetics; Estrogen; Mitochondria; Ovariectomy; Oxidative stress

Indexed keywords

AMYLOID BETA PROTEIN; BETA AMYLOID BINDING ALCOHOL DEHYDROGENASE; ESTRADIOL; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

EID: 84861895505     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2011.03.001     Document Type: Article
Times cited : (98)

References (59)
  • 1
    • 77949336151 scopus 로고    scopus 로고
    • 2010 Alzheimer's disease facts and figures
    • Alzheimer's Association
    • 2010 Alzheimer's disease facts and figures. Alzheimers Dement 2010, 6:158-194. Alzheimer's Association.
    • (2010) Alzheimers Dement , vol.6 , pp. 158-194
  • 3
    • 25444474703 scopus 로고    scopus 로고
    • Mitochondria take center stage in aging and neurodegeneration
    • Beal M.F. Mitochondria take center stage in aging and neurodegeneration. Ann. Neurol 2005, 58:495-505.
    • (2005) Ann. Neurol , vol.58 , pp. 495-505
    • Beal, M.F.1
  • 6
    • 0034103586 scopus 로고    scopus 로고
    • Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise
    • Blass J.P., Sheu R.K., Gibson G.E. Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise. Ann. N.Y. Acad. Sci 2000, 903:204-221.
    • (2000) Ann. N.Y. Acad. Sci , vol.903 , pp. 204-221
    • Blass, J.P.1    Sheu, R.K.2    Gibson, G.E.3
  • 7
    • 52049083656 scopus 로고    scopus 로고
    • The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications
    • Brinton R.D. The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications. Trends Neurosci 2008, 31:529-537.
    • (2008) Trends Neurosci , vol.31 , pp. 529-537
    • Brinton, R.D.1
  • 8
    • 62949120140 scopus 로고    scopus 로고
    • Estrogen-induced plasticity from cells to circuits: predictions for cognitive function
    • Brinton R.D. Estrogen-induced plasticity from cells to circuits: predictions for cognitive function. Trends Pharmacol. Sci 2009, 30:212-222.
    • (2009) Trends Pharmacol. Sci , vol.30 , pp. 212-222
    • Brinton, R.D.1
  • 9
    • 0033796250 scopus 로고    scopus 로고
    • Mitochondrial free radical generation, oxidative stress, and aging
    • Cadenas E., Davies K.J. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic. Biol. Med 2000, 29:222-230.
    • (2000) Free Radic. Biol. Med , vol.29 , pp. 222-230
    • Cadenas, E.1    Davies, K.J.2
  • 10
    • 42449163010 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators differentially regulate Alzheimer-like changes in female 3xTg-AD mice
    • Carroll J.C., Pike C.J. Selective estrogen receptor modulators differentially regulate Alzheimer-like changes in female 3xTg-AD mice. Endocrinology 2008, 149:2607-2611.
    • (2008) Endocrinology , vol.149 , pp. 2607-2611
    • Carroll, J.C.1    Pike, C.J.2
  • 12
    • 33745274726 scopus 로고    scopus 로고
    • Mitochondria: dynamic organelles in disease, aging, and development
    • Chan D.C. Mitochondria: dynamic organelles in disease, aging, and development. Cell 2006, 125:1241-1252.
    • (2006) Cell , vol.125 , pp. 1241-1252
    • Chan, D.C.1
  • 13
    • 64249133725 scopus 로고    scopus 로고
    • S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury
    • Cho D.H., Nakamura T., Fang J., Cieplak P., Godzik A., Gu Z., Lipton S.A. S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. Science 2009, 324:102-105.
    • (2009) Science , vol.324 , pp. 102-105
    • Cho, D.H.1    Nakamura, T.2    Fang, J.3    Cieplak, P.4    Godzik, A.5    Gu, Z.6    Lipton, S.A.7
  • 14
    • 0030016323 scopus 로고    scopus 로고
    • Increased risk of dementia in mothers of Alzheimer's disease cases: evidence for maternal inheritance
    • Edland S.D., Silverman J.M., Peskind E.R., Tsuang D., Wijsman E., Morris J.C. Increased risk of dementia in mothers of Alzheimer's disease cases: evidence for maternal inheritance. Neurology 1996, 47:254-256.
    • (1996) Neurology , vol.47 , pp. 254-256
    • Edland, S.D.1    Silverman, J.M.2    Peskind, E.R.3    Tsuang, D.4    Wijsman, E.5    Morris, J.C.6
  • 15
    • 0028201821 scopus 로고
    • APP processing, A beta-amyloidogenesis, and the pathogenesis of Alzheimer's disease
    • Gandy S., Caporaso G., Buxbaum J., Frangione B., Greengard P. APP processing, A beta-amyloidogenesis, and the pathogenesis of Alzheimer's disease. Neurobiol. Aging 1994, 15:253-256.
    • (1994) Neurobiol. Aging , vol.15 , pp. 253-256
    • Gandy, S.1    Caporaso, G.2    Buxbaum, J.3    Frangione, B.4    Greengard, P.5
  • 17
    • 77956178214 scopus 로고    scopus 로고
    • Menopause and mitochondria: windows into estrogen effects on Alzheimer's disease risk and therapy: progress in brain research
    • Henderson V.W. Menopause and mitochondria: windows into estrogen effects on Alzheimer's disease risk and therapy: progress in brain research. Neuroendocrinology 2010, 182:77-96.
    • (2010) Neuroendocrinology , vol.182 , pp. 77-96
    • Henderson, V.W.1
  • 19
  • 20
    • 77951624019 scopus 로고    scopus 로고
    • Aging and ovariectomy cause a decrease in brain glucose consumption in vivo in Wistar rats [in Spanish]
    • Lopez-Grueso R., Borras C., Gambini J., Viña J. Aging and ovariectomy cause a decrease in brain glucose consumption in vivo in Wistar rats [in Spanish]. Rev. Esp. Geriatr. Gerontol 2010, 45:136-140.
    • (2010) Rev. Esp. Geriatr. Gerontol , vol.45 , pp. 136-140
    • Lopez-Grueso, R.1    Borras, C.2    Gambini, J.3    Viña, J.4
  • 22
    • 33745988312 scopus 로고    scopus 로고
    • Neuron-glia metabolic coupling and plasticity
    • Magistretti P.J. Neuron-glia metabolic coupling and plasticity. J. Exp. Biol 2006, 209:2304-2311.
    • (2006) J. Exp. Biol , vol.209 , pp. 2304-2311
    • Magistretti, P.J.1
  • 24
    • 0034603609 scopus 로고    scopus 로고
    • Longitudinal effects of estrogen replacement therapy on PET cerebral blood flow and cognition
    • Maki P.M., Resnick S.M. Longitudinal effects of estrogen replacement therapy on PET cerebral blood flow and cognition. Neurobiol. Aging 2000, 21:373-383.
    • (2000) Neurobiol. Aging , vol.21 , pp. 373-383
    • Maki, P.M.1    Resnick, S.M.2
  • 25
    • 0034805892 scopus 로고    scopus 로고
    • Effects of estrogen on patterns of brain activity at rest and during cognitive activity: a review of neuroimaging studies
    • Maki P.M., Resnick S.M. Effects of estrogen on patterns of brain activity at rest and during cognitive activity: a review of neuroimaging studies. Neuroimage 2001, 14:789-801.
    • (2001) Neuroimage , vol.14 , pp. 789-801
    • Maki, P.M.1    Resnick, S.M.2
  • 26
    • 2942749992 scopus 로고    scopus 로고
    • Age at onset: important marker of genetic heterogeneity in Alzheimer's disease
    • Martins R.N., Hallmayer J. Age at onset: important marker of genetic heterogeneity in Alzheimer's disease. Pharmacogenomics J 2004, 4:138-140.
    • (2004) Pharmacogenomics J , vol.4 , pp. 138-140
    • Martins, R.N.1    Hallmayer, J.2
  • 27
    • 34249821079 scopus 로고    scopus 로고
    • Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes
    • Moreira P.I., Santos M.S., Seiça R., Oliveira C.R. Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes. J. Neurol. Sci 2007, 257:206-214.
    • (2007) J. Neurol. Sci , vol.257 , pp. 206-214
    • Moreira, P.I.1    Santos, M.S.2    Seiça, R.3    Oliveira, C.R.4
  • 32
    • 77955981090 scopus 로고    scopus 로고
    • Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models
    • Nicholson R.M., Kusne Y., Nowak L.A., Laferla F.M., Reiman E.M., Valla J. Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models. Brain Res 2010, 1347:179-185.
    • (2010) Brain Res , vol.1347 , pp. 179-185
    • Nicholson, R.M.1    Kusne, Y.2    Nowak, L.A.3    Laferla, F.M.4    Reiman, E.M.5    Valla, J.6
  • 33
    • 38449089795 scopus 로고    scopus 로고
    • Estradiol in vivo regulation of brain mitochondrial proteome
    • Nilsen J., Irwin R.W., Gallaher T.K., Brinton R.D. Estradiol in vivo regulation of brain mitochondrial proteome. J. Neurosci 2007, 27:14069-14077.
    • (2007) J. Neurosci , vol.27 , pp. 14069-14077
    • Nilsen, J.1    Irwin, R.W.2    Gallaher, T.K.3    Brinton, R.D.4
  • 36
    • 0034720686 scopus 로고    scopus 로고
    • Ovariectomy and 17beta-estradiol modulate the levels of Alzheimer's amyloid beta peptides in brain
    • Petanceska S.S., Nagy V., Frail D., Gandy S. Ovariectomy and 17beta-estradiol modulate the levels of Alzheimer's amyloid beta peptides in brain. Neurology 2000, 54:2212-2217.
    • (2000) Neurology , vol.54 , pp. 2212-2217
    • Petanceska, S.S.1    Nagy, V.2    Frail, D.3    Gandy, S.4
  • 38
    • 39149122810 scopus 로고    scopus 로고
    • Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
    • Reddy P.H., Beal M.F. Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol. Med 2008, 14:45-53.
    • (2008) Trends Mol. Med , vol.14 , pp. 45-53
    • Reddy, P.H.1    Beal, M.F.2
  • 39
    • 34247631332 scopus 로고    scopus 로고
    • Linking brain imaging and genomics in the study of Alzheimer's disease and aging
    • Reiman E.M. Linking brain imaging and genomics in the study of Alzheimer's disease and aging. Ann. N. Y. Acad. Sci 2007, 1097:94-113.
    • (2007) Ann. N. Y. Acad. Sci , vol.1097 , pp. 94-113
    • Reiman, E.M.1
  • 42
    • 77449147924 scopus 로고    scopus 로고
    • Oophorectomy, Menopause, estrogen, and cognitive aging: the timing hypothesis
    • Rocca W.A., Grossardt B.R., Shuster L.T. Oophorectomy, Menopause, estrogen, and cognitive aging: the timing hypothesis. Neurodegener. Dis 2010, 7:163-166.
    • (2010) Neurodegener. Dis , vol.7 , pp. 163-166
    • Rocca, W.A.1    Grossardt, B.R.2    Shuster, L.T.3
  • 44
    • 40749118030 scopus 로고    scopus 로고
    • Mitochondrial mechanisms of estrogen neuroprotection
    • Simpkins J.W., Dykens J.A. Mitochondrial mechanisms of estrogen neuroprotection. Brain Res. Rev 2008, 57:421-430.
    • (2008) Brain Res. Rev , vol.57 , pp. 421-430
    • Simpkins, J.W.1    Dykens, J.A.2
  • 46
    • 67649687124 scopus 로고    scopus 로고
    • The Alzheimer's disease mitochondrial cascade hypothesis: an update
    • Swerdlow R.H., Khan S.M. The Alzheimer's disease mitochondrial cascade hypothesis: an update. Exp. Neurol 2009, 218:308-315.
    • (2009) Exp. Neurol , vol.218 , pp. 308-315
    • Swerdlow, R.H.1    Khan, S.M.2
  • 48
    • 28044458281 scopus 로고    scopus 로고
    • Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis
    • Velliquette R.A., O'Connor T., Vassar R. Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis. J. Neurosci 2005, 25:10874-10883.
    • (2005) J. Neurosci , vol.25 , pp. 10874-10883
    • Velliquette, R.A.1    O'Connor, T.2    Vassar, R.3
  • 49
    • 18244393163 scopus 로고    scopus 로고
    • Why females live longer than males?. Importance of the upregulation of longevity-associated genes by oestrogenic compounds
    • Viña J., Borrás C., Gambini J., Sastre J., Pallardó F.V. Why females live longer than males?. Importance of the upregulation of longevity-associated genes by oestrogenic compounds. FEBS Lett 2005, 579:2541-2545.
    • (2005) FEBS Lett , vol.579 , pp. 2541-2545
    • Viña, J.1    Borrás, C.2    Gambini, J.3    Sastre, J.4    Pallardó, F.V.5
  • 50
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
    • Wallace D.C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet 2005, 39:359-407.
    • (2005) Annu. Rev. Genet , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 51
    • 67650732998 scopus 로고    scopus 로고
    • Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
    • Wang X., Su B., Lee H.G., Li X., Perry G., Smith M.A., Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J. Neurosci 2009, 29:9090-9103.
    • (2009) J. Neurosci , vol.29 , pp. 9090-9103
    • Wang, X.1    Su, B.2    Lee, H.G.3    Li, X.4    Perry, G.5    Smith, M.A.6    Zhu, X.7
  • 52
    • 79551493889 scopus 로고    scopus 로고
    • Timing of hormone therapy and dementia: The critical window theory revisited
    • Whitmer R.A., Quesenberry C.P., Zhou J., Yaffe K. Timing of hormone therapy and dementia: The critical window theory revisited. Ann. Neurol 2011, 69:163-169.
    • (2011) Ann. Neurol , vol.69 , pp. 163-169
    • Whitmer, R.A.1    Quesenberry, C.P.2    Zhou, J.3    Yaffe, K.4
  • 53
    • 34147159979 scopus 로고    scopus 로고
    • Analysis of mitochondrial function using phosphorescent oxygen-sensitive probes
    • Will Y., Hynes J., Ogurtsov V.I., Papkovsky D.B. Analysis of mitochondrial function using phosphorescent oxygen-sensitive probes. Nat. Protoc 2006, 1:2563-2572.
    • (2006) Nat. Protoc , vol.1 , pp. 2563-2572
    • Will, Y.1    Hynes, J.2    Ogurtsov, V.I.3    Papkovsky, D.B.4
  • 55
    • 44949213717 scopus 로고    scopus 로고
    • Mitochondrial DNA damage and repair in neurodegenerative disorders
    • Yang J.L., Weissman L., Bohr V.A., Mattson M.P. Mitochondrial DNA damage and repair in neurodegenerative disorders. DNA Repair (Amst) 2008, 7:1110-1120.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1110-1120
    • Yang, J.L.1    Weissman, L.2    Bohr, V.A.3    Mattson, M.P.4
  • 56
    • 77956179987 scopus 로고    scopus 로고
    • Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence
    • Yao J., Hamilton R.T., Cadenas E., Brinton R.D. Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence. Biochim. Biophys. Acta 2010, 1800:1121-1126.
    • (2010) Biochim. Biophys. Acta , vol.1800 , pp. 1121-1126
    • Yao, J.1    Hamilton, R.T.2    Cadenas, E.3    Brinton, R.D.4
  • 57
    • 70149093436 scopus 로고    scopus 로고
    • Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
    • Yao J., Irwin R.W., Zhao L., Nilsen J., Hamilton R.T., Brinton R.D. Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:14670-14675.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 14670-14675
    • Yao, J.1    Irwin, R.W.2    Zhao, L.3    Nilsen, J.4    Hamilton, R.T.5    Brinton, R.D.6
  • 58
    • 0037032401 scopus 로고    scopus 로고
    • Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study
    • Cache County Memory Study Investigators
    • Zandi P.P., Carlson M.C., Plassman B.L., Welsh-Bohmer K.A., Mayer L.S., Steffens D.C., Breitner J.C. Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study. JAMA 2002, 288:2123-2129. Cache County Memory Study Investigators.
    • (2002) JAMA , vol.288 , pp. 2123-2129
    • Zandi, P.P.1    Carlson, M.C.2    Plassman, B.L.3    Welsh-Bohmer, K.A.4    Mayer, L.S.5    Steffens, D.C.6    Breitner, J.C.7
  • 59
    • 80052640194 scopus 로고    scopus 로고
    • Estradiol regulates insulin-degrading enzyme expression via an ERbeta/PI3-K pathway in hippocampus: Relevance to Alzheimer's prevention
    • 2010 Jan 4. [Epub ahead of print]
    • Zhao d.L., Yao J., Mao Z., Chen S., Wang Y., Brinton R.D. Estradiol regulates insulin-degrading enzyme expression via an ERbeta/PI3-K pathway in hippocampus: Relevance to Alzheimer's prevention. Neurobiol. Aging 2010, 2010 Jan 4. [Epub ahead of print]. 10.1016/j.neurobiolaging.2009.12.010.
    • (2010) Neurobiol. Aging
    • Zhao, D.1    Yao, J.2    Mao, Z.3    Chen, S.4    Wang, Y.5    Brinton, R.D.6


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