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Volumn 41, Issue 9, 2014, Pages 459-463

Rapamycin and Ageing: When, for How Long, and How Much?

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN;

EID: 84908897552     PISSN: 16738527     EISSN: 18735533     Source Type: Journal    
DOI: 10.1016/j.jgg.2014.06.009     Document Type: Article
Times cited : (33)

References (37)
  • 1
    • 84863403169 scopus 로고    scopus 로고
    • The caloric restriction paradigm: implications for healthy human aging
    • Anderson R.M., Weindruch R. The caloric restriction paradigm: implications for healthy human aging. Am. J. Hum. Biol. 2012, 24:101-106.
    • (2012) Am. J. Hum. Biol. , vol.24 , pp. 101-106
    • Anderson, R.M.1    Weindruch, R.2
  • 4
    • 75549090275 scopus 로고    scopus 로고
    • MTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells
    • Chen C., Liu Y., Zheng P. mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells. Sci. Signal. 2009, 2:ra75.
    • (2009) Sci. Signal. , vol.2 , pp. ra75
    • Chen, C.1    Liu, Y.2    Zheng, P.3
  • 5
    • 77957226879 scopus 로고    scopus 로고
    • Drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans
    • Ching T.T., Paal A.B., Mehta A., Zhong L., Hsu A.L. drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans. Aging Cell 2010, 9:545-557.
    • (2010) Aging Cell , vol.9 , pp. 545-557
    • Ching, T.T.1    Paal, A.B.2    Mehta, A.3    Zhong, L.4    Hsu, A.L.5
  • 6
    • 1642491749 scopus 로고    scopus 로고
    • Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae
    • Fabrizio P., Pletcher S.D., Minois N., Vaupel J.W., Longo V.D. Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae. FEBS Lett. 2004, 557:136-142.
    • (2004) FEBS Lett. , vol.557 , pp. 136-142
    • Fabrizio, P.1    Pletcher, S.D.2    Minois, N.3    Vaupel, J.W.4    Longo, V.D.5
  • 7
  • 10
    • 4544311861 scopus 로고    scopus 로고
    • The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
    • Jia K., Chen D., Riddle D.L. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 2004, 131:3897-3906.
    • (2004) Development , vol.131 , pp. 3897-3906
    • Jia, K.1    Chen, D.2    Riddle, D.L.3
  • 12
    • 84872527628 scopus 로고    scopus 로고
    • MTOR is a key modulator of ageing and age-related disease
    • Johnson S.C., Rabinovitch P.S., Kaeberlein M. mTOR is a key modulator of ageing and age-related disease. Nature 2013, 493:338-345.
    • (2013) Nature , vol.493 , pp. 338-345
    • Johnson, S.C.1    Rabinovitch, P.S.2    Kaeberlein, M.3
  • 15
    • 84898663324 scopus 로고    scopus 로고
    • MTOR inhibition: from aging to autism and beyond
    • Kaeberlein M. mTOR inhibition: from aging to autism and beyond. Scientifica (Cairo) 2013, 2013:849186.
    • (2013) Scientifica (Cairo) , vol.2013 , pp. 849186
    • Kaeberlein, M.1
  • 17
    • 77955747346 scopus 로고    scopus 로고
    • With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging
    • Kapahi P., Chen D., Rogers A.N., Katewa S.D., Li P.W., Thomas E.L., Kockel L. With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab. 2010, 11:453-465.
    • (2010) Cell Metab. , vol.11 , pp. 453-465
    • Kapahi, P.1    Chen, D.2    Rogers, A.N.3    Katewa, S.D.4    Li, P.W.5    Thomas, E.L.6    Kockel, L.7
  • 19
    • 3042648746 scopus 로고    scopus 로고
    • Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
    • Kapahi P., Zid B.M., Harper T., Koslover D., Sapin V., Benzer S. Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr. Biol. 2004, 14:885-890.
    • (2004) Curr. Biol. , vol.14 , pp. 885-890
    • Kapahi, P.1    Zid, B.M.2    Harper, T.3    Koslover, D.4    Sapin, V.5    Benzer, S.6
  • 22
    • 84859778293 scopus 로고    scopus 로고
    • MTOR signaling in growth control and disease
    • Laplante M., Sabatini D.M. mTOR signaling in growth control and disease. Cell 2012, 149:274-293.
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 23
    • 22744445281 scopus 로고    scopus 로고
    • Overview of caloric restriction and ageing
    • Masoro E.J. Overview of caloric restriction and ageing. Mech. Ageing Dev. 2005, 126:913-922.
    • (2005) Mech. Ageing Dev. , vol.126 , pp. 913-922
    • Masoro, E.J.1
  • 24
    • 35648995939 scopus 로고    scopus 로고
    • MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae
    • Medvedik O., Lamming D.W., Kim K.D., Sinclair D.A. MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. PLoS Biol. 2007, 5:e261.
    • (2007) PLoS Biol. , vol.5 , pp. e261
    • Medvedik, O.1    Lamming, D.W.2    Kim, K.D.3    Sinclair, D.A.4
  • 30
    • 30944458446 scopus 로고    scopus 로고
    • Extension of chronological life span in yeast by decreased TOR pathway signaling
    • Powers R.W., Kaeberlein M., Caldwell S.D., Kennedy B.K., Fields S. Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev. 2006, 20:174-184.
    • (2006) Genes Dev. , vol.20 , pp. 174-184
    • Powers, R.W.1    Kaeberlein, M.2    Caldwell, S.D.3    Kennedy, B.K.4    Fields, S.5
  • 37


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.