메뉴 건너뛰기




Volumn 9, Issue 11, 2014, Pages 1651-1664

RNAi-mediated inhibition of apoptosis fails to prevent cationic nanoparticle-induced cell death in cultured cells

Author keywords

apoptosis; caspase; cationic nanoparticle; nanotoxicity; RNAi

Indexed keywords

AMINE; APOPTOSOME; BIM PROTEIN; POLYSTYRENE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PUMA PROTEIN; CASPASE 3; CASPASE 7; CATION; NANOPARTICLE; POLYSTYRENE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

EID: 84908880951     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.13.151     Document Type: Article
Times cited : (17)

References (39)
  • 2
    • 84880511751 scopus 로고    scopus 로고
    • Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide
    • Shmueli RB, Ohnaka M, Miki A et al. Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide. Biomaterials 34 (30), 7544-7551 (2013).
    • (2013) Biomaterials , vol.34 , Issue.30 , pp. 7544-7551
    • Shmueli, R.B.1    Ohnaka, M.2    Miki, A.3
  • 3
    • 84902124441 scopus 로고    scopus 로고
    • Polymeric materials for theranostic applications
    • Epub ahead of print
    • Wang Z, Niu G, Chen X. Polymeric materials for theranostic applications. Pharm. Res. doi:10.1007/s11095-013-1103-1107 (2013) (Epub ahead of print).
    • (2013) Pharm. Res
    • Wang, Z.1    Niu, G.2    Chen, X.3
  • 5
    • 34147106483 scopus 로고    scopus 로고
    • Toxicology of nanoparticles: A historical perspective
    • Oberdörster G, Stone V, Donaldson K. Toxicology of nanoparticles: a historical perspective. Nanotoxicology 1 (1), 2-25 (2007).
    • (2007) Nanotoxicology , vol.1 , Issue.1 , pp. 2-25
    • Oberdörster, G.1    Stone, V.2    Donaldson, K.3
  • 6
    • 0035881235 scopus 로고    scopus 로고
    • Cationic liposomes induce macrophage apoptosis through mitochondrial pathway
    • Aramaki Y, Takano S, Tsuchiya S. Cationic liposomes induce macrophage apoptosis through mitochondrial pathway. Arch. Biochem. Biophys. 392 (2), 245-250 (2001).
    • (2001) Arch. Biochem. Biophys. , vol.392 , Issue.2 , pp. 245-250
    • Aramaki, Y.1    Takano, S.2    Tsuchiya, S.3
  • 7
    • 30144442122 scopus 로고    scopus 로고
    • Cationic liposomes induce apoptosis through p38 MAP kinase-caspase-8-Bid pathway in macrophage-like RAW264.7 cells
    • Iwaoka S, Nakamura T, Takano S, Tsuchiya S, Aramaki Y. Cationic liposomes induce apoptosis through p38 MAP kinase-caspase-8-Bid pathway in macrophage-like RAW264.7 cells. J. Leukoc. Biol. 79 (1), 184-191 (2006).
    • (2006) J. Leukoc. Biol. , vol.79 , Issue.1 , pp. 184-191
    • Iwaoka, S.1    Nakamura, T.2    Takano, S.3    Tsuchiya, S.4    Aramaki, Y.5
  • 8
    • 33746438424 scopus 로고    scopus 로고
    • Toxicity of cationic lipids and cationic polymers in gene delivery
    • Lv H, Zhang S, Wang B, Cui S, Yan J. Toxicity of cationic lipids and cationic polymers in gene delivery. J. Control. Release 114 (1), 100-109 (2006).
    • (2006) J. Control. Release , vol.114 , Issue.1 , pp. 100-109
    • Lv, H.1    Zhang, S.2    Wang, B.3    Cui, S.4    Yan, J.5
  • 9
    • 80655125242 scopus 로고    scopus 로고
    • Cationic nanoparticles induce caspase 3-, 7-and 9-mediated cytotoxicity in a human astrocytoma cell line
    • Bexiga MG, Varela JA, Wang F et al. Cationic nanoparticles induce caspase 3-, 7-and 9-mediated cytotoxicity in a human astrocytoma cell line. Nanotoxicology 5 (4), 557-567 (2011).
    • (2011) Nanotoxicology , vol.5 , Issue.4 , pp. 557-567
    • Bexiga, M.G.1    Varela, J.A.2    Wang, F.3
  • 10
    • 42649099670 scopus 로고    scopus 로고
    • Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways
    • Xia T, Kovochich M, Liong M, Zink JI, Nel AE. Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. ACS Nano 2 (1), 85-96 (2008).
    • (2008) ACS Nano , vol.2 , Issue.1 , pp. 85-96
    • Xia, T.1    Kovochich, M.2    Liong, M.3    Zink, J.I.4    Nel, A.E.5
  • 11
    • 38049119903 scopus 로고    scopus 로고
    • Overlapping cleavage motif selectivity of caspases: Implications for analysis of apoptotic pathways
    • Mcstay GP, Salvesen GS, Green DR. Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways. Cell Death Differ. 15 (2), 322-331 (2008).
    • (2008) Cell Death Differ. , vol.15 , Issue.2 , pp. 322-331
    • McStay, G.P.1    Salvesen, G.S.2    Green, D.R.3
  • 12
    • 7444252784 scopus 로고    scopus 로고
    • Human ORFeome version 1.1: A platform for reverse proteomics
    • Rual JF, Hirozane-Kishikawa T, Hao T et al. Human ORFeome version 1.1: a platform for reverse proteomics. Genome Res. 14 (10B), 2128-2135 (2004).
    • (2004) Genome Res. , vol.14 B , Issue.10 , pp. 2128-2135
    • Rual, J.F.1    Hirozane-Kishikawa, T.2    Hao, T.3
  • 13
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391 (6669), 806-811 (1998).
    • (1998) Nature , vol.391 , Issue.6669 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 14
    • 33845755467 scopus 로고    scopus 로고
    • Illuminating the silence: Understanding the structure and function of small RNAs
    • Rana TM. Illuminating the silence: understanding the structure and function of small RNAs. Nat. Rev. Mol. Cell Biol. 8 (1), 23-36 (2007).
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , Issue.1 , pp. 23-36
    • Rana, T.M.1
  • 15
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • Kim DH, Rossi JJ. Strategies for silencing human disease using RNA interference. Nat. Rev. Genet. 8 (3), 173-184 (2007).
    • (2007) Nat. Rev. Genet. , vol.8 , Issue.3 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 16
    • 77950387346 scopus 로고    scopus 로고
    • Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
    • Neumann B, Walter T, Heriche JK et al. Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature 464 (7289), 721-727 (2010).
    • (2010) Nature , vol.464 , Issue.7289 , pp. 721-727
    • Neumann, B.1    Walter, T.2    Heriche, J.K.3
  • 17
    • 84863205689 scopus 로고    scopus 로고
    • Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway
    • Simpson JC, Joggerst B, Laketa V et al. Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Nat. Cell Biol. 14 (7), 764-774 (2012).
    • (2012) Nat. Cell Biol. , vol.14 , Issue.7 , pp. 764-774
    • Simpson, J.C.1    Joggerst, B.2    Laketa, V.3
  • 18
    • 0141750434 scopus 로고    scopus 로고
    • Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
    • Aza-Blanc P, Cooper CL, Wagner K, Batalov S, Deveraux QL, Cooke MP. Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Mol. Cell 12 (3), 627-637 (2003).
    • (2003) Mol. Cell , vol.12 , Issue.3 , pp. 627-637
    • Aza-Blanc, P.1    Cooper, C.L.2    Wagner, K.3    Batalov, S.4    Deveraux, Q.L.5    Cooke, M.P.6
  • 20
    • 42149103828 scopus 로고    scopus 로고
    • Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid β-42 and α-synuclein in children and young adults
    • Calderon-Garciduenas L, Solt AC, Henriquez-Roldan C et al. Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid -42 and α-synuclein in children and young adults. Toxicol. Pathol. 36 (2), 289-310 (2008).
    • (2008) Toxicol. Pathol. , vol.36 , Issue.2 , pp. 289-310
    • Calderon-Garciduenas, L.1    Solt, A.C.2    Henriquez-Roldan, C.3
  • 21
    • 69549103145 scopus 로고    scopus 로고
    • Recent advances in our understanding of neurodegeneration
    • Jellinger KA. Recent advances in our understanding of neurodegeneration. J. Neural. Transm. 116 (9), 1111-1162 (2009).
    • (2009) J. Neural. Transm. , vol.116 , Issue.9 , pp. 1111-1162
    • Jellinger, K.A.1
  • 22
    • 0033800844 scopus 로고    scopus 로고
    • Molecular mechanism of staurosporine-induced apoptosis in osteoblasts
    • Chae HJ, Kang JS, Byun JO et al. Molecular mechanism of staurosporine-induced apoptosis in osteoblasts. Pharmacol. Res. 42 (4), 373-381 (2000).
    • (2000) Pharmacol. Res. , vol.42 , Issue.4 , pp. 373-381
    • Chae, H.J.1    Kang, J.S.2    Byun, J.O.3
  • 23
    • 18944390248 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
    • Jagtap P, Szabo C. Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat. Rev. Drug Discov. 4 (5), 421-440 (2005).
    • (2005) Nat. Rev. Drug Discov. , vol.4 , Issue.5 , pp. 421-440
    • Jagtap, P.1    Szabo, C.2
  • 24
    • 80055087827 scopus 로고    scopus 로고
    • Automatic morphological subtyping reveals new roles of caspases in mitochondrial dynamics
    • Peng JY, Lin CC, Chen YJ et al. Automatic morphological subtyping reveals new roles of caspases in mitochondrial dynamics. PLoS Computat. Biol. 7 (10), e1002212 (2011).
    • (2011) PLoS Computat. Biol. , vol.7 , Issue.10 , pp. e1002212
    • Peng, J.Y.1    Lin, C.C.2    Chen, Y.J.3
  • 25
    • 84886447813 scopus 로고    scopus 로고
    • The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes
    • Wang F, Yu L, Monopoli MP et al. The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes. Nanomedicine 9 (8), 1159-1168 (2013).
    • (2013) Nanomedicine , vol.9 , Issue.8 , pp. 1159-1168
    • Wang, F.1    Yu, L.2    Monopoli, M.P.3
  • 27
    • 34247345833 scopus 로고    scopus 로고
    • The apoptosome: Signalling platform of cell death
    • Riedl SJ, Salvesen GS. The apoptosome: signalling platform of cell death. Nat. Rev. Mol. Cell Biol. 8 (5), 405-413 (2007).
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , Issue.5 , pp. 405-413
    • Riedl, S.J.1    Salvesen, G.S.2
  • 28
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • Youle RJ, Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 9 (1), 47-59 (2008).
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , Issue.1 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 29
    • 34247497716 scopus 로고    scopus 로고
    • Embedded together: The life and death consequences of interaction of the Bcl-2 family with membranes
    • Leber B, Lin J, Andrews DW. Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes. Apoptosis 12 (5), 897-911 (2007).
    • (2007) Apoptosis , vol.12 , Issue.5 , pp. 897-911
    • Leber, B.1    Lin, J.2    Andrews, D.W.3
  • 30
    • 33751504957 scopus 로고    scopus 로고
    • Upgrading the BCL-2 network
    • Galonek HL, Hardwick JM. Upgrading the BCL-2 network. Nat. Cell Biol. 8 (12), 1317-1319 (2006).
    • (2006) Nat. Cell Biol. , vol.8 , Issue.12 , pp. 1317-1319
    • Galonek, H.L.1    Hardwick, J.M.2
  • 31
    • 78649700978 scopus 로고    scopus 로고
    • BID, BIM, and PUMA are essential for activation of the BAX-and BAK-dependent cell death program
    • Ren D, Tu HC, Kim H et al. BID, BIM, and PUMA are essential for activation of the BAX-and BAK-dependent cell death program. Science 330 (6009), 1390-1393 (2010).
    • (2010) Science , vol.330 , Issue.6009 , pp. 1390-1393
    • Ren, D.1    Tu, H.C.2    Kim, H.3
  • 32
    • 68149108384 scopus 로고    scopus 로고
    • PUMA, a potent killer with or without p53
    • Yu J, Zhang L. PUMA, a potent killer with or without p53. Oncogene 27 (Suppl. 1), S71-S83 (2008).
    • (2008) Oncogene , vol.27 , pp. S71-S83
    • Yu, J.1    Zhang, L.2
  • 33
    • 65349152495 scopus 로고    scopus 로고
    • Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members
    • Gallenne T, Gautier F, Oliver L et al. Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members. J. Cell Biol. 185 (2), 279-290 (2009).
    • (2009) J. Cell Biol. , vol.185 , Issue.2 , pp. 279-290
    • Gallenne, T.1    Gautier, F.2    Oliver, L.3
  • 34
    • 62849097807 scopus 로고    scopus 로고
    • Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim
    • Jabbour AM, Heraud JE, Daunt CP et al. Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell Death Differ. 16 (4), 555-563 (2009).
    • (2009) Cell Death Differ. , vol.16 , Issue.4 , pp. 555-563
    • Jabbour, A.M.1    Heraud, J.E.2    Daunt, C.P.3
  • 35
    • 27644585945 scopus 로고    scopus 로고
    • Redundant cell death mechanisms as relics and backups
    • Golstein P, Kroemer G. Redundant cell death mechanisms as relics and backups. Cell Death Differ. 12 (Suppl. 2), 1490-1496 (2005).
    • (2005) Cell Death Differ. , vol.12 , pp. 1490-1496
    • Golstein, P.1    Kroemer, G.2
  • 36
    • 14644412456 scopus 로고    scopus 로고
    • Do inducers of apoptosis trigger caspase-independent cell death?
    • Chipuk JE, Green DR. Do inducers of apoptosis trigger caspase-independent cell death? Nat. Rev. Mol. Cell Biol. 6 (3), 268-275 (2005).
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , Issue.3 , pp. 268-275
    • Chipuk, J.E.1    Green, D.R.2
  • 37
    • 22544444514 scopus 로고    scopus 로고
    • Caspase-independent cell death
    • Kroemer G, Martin SJ. Caspase-independent cell death. Nat. Med. 11 (7), 725-730 (2005).
    • (2005) Nat. Med. , vol.11 , Issue.7 , pp. 725-730
    • Kroemer, G.1    Martin, S.J.2
  • 39
    • 2642536197 scopus 로고    scopus 로고
    • Alkylating DNA damage stimulates a regulated form of necrotic cell death
    • Zong WX, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev. 18 (11), 1272-1282 (2004).
    • (2004) Genes Dev. , vol.18 , Issue.11 , pp. 1272-1282
    • Zong, W.X.1    Ditsworth, D.2    Bauer, D.E.3    Wang, Z.Q.4    Thompson, C.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.