메뉴 건너뛰기




Volumn 13, Issue 11, 2014, Pages 5094-5105

Whole serum 3D LC-nESI-FTMS quantitative proteomics reveals sexual dimorphism in the milieu intérieur of overweight and obese adults

Author keywords

cardiovascular physiology; depletion free; FT MS; iTRAQ; multiplex quantitative proteomics; sexual dimorphism; size exclusion chromatography; subproteome enrichment; whole serum milieu int rieur

Indexed keywords

ESTRADIOL; LIPID; PROSTANOID; PROTEOME; VITAMIN D; PLASMA PROTEIN; TRANSCRIPTOME;

EID: 84908879504     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5003406     Document Type: Article
Times cited : (58)

References (64)
  • 1
    • 84858297008 scopus 로고    scopus 로고
    • The link between obesity and low circulating 25-hydroxyvitamin D concentrations: Considerations and implications
    • Earthman, C. P.; Beckman, L. M.; Masodkar, K.; Sibley, S. D. The link between obesity and low circulating 25-hydroxyvitamin D concentrations: considerations and implications Int. J. Obes. 2012, 36 (3) 387-96
    • (2012) Int. J. Obes. , vol.36 , Issue.3 , pp. 387-396
    • Earthman, C.P.1    Beckman, L.M.2    Masodkar, K.3    Sibley, S.D.4
  • 2
    • 84898748705 scopus 로고    scopus 로고
    • The need for serological markers of response to vitamin D status optimization: A case for quantitative serum proteomics
    • Al-Daghri, N. M.; Garbis, S. D. The need for serological markers of response to vitamin D status optimization: a case for quantitative serum proteomics Bioanalysis 2014, 6 (6) 721-3
    • (2014) Bioanalysis , vol.6 , Issue.6 , pp. 721-723
    • Al-Daghri, N.M.1    Garbis, S.D.2
  • 4
    • 84890547453 scopus 로고    scopus 로고
    • The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications
    • Madsbad, S. The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications Diabetes Obes. Metab. 2014, 16 (1) 9-21
    • (2014) Diabetes Obes. Metab. , vol.16 , Issue.1 , pp. 9-21
    • Madsbad, S.1
  • 5
    • 57749184775 scopus 로고    scopus 로고
    • Sex-dependent role of glucocorticoids and androgens in the pathophysiology of human obesity
    • Pasquali, R.; Vicennati, V.; Gambineri, A.; Pagotto, U. Sex-dependent role of glucocorticoids and androgens in the pathophysiology of human obesity Int. J. Obes. 2008, 32 (12) 1764-79
    • (2008) Int. J. Obes. , vol.32 , Issue.12 , pp. 1764-1779
    • Pasquali, R.1    Vicennati, V.2    Gambineri, A.3    Pagotto, U.4
  • 6
    • 33747627417 scopus 로고    scopus 로고
    • Visceral obesity, the metabolic syndrome, androgens and estrogens
    • Gooren, L. Visceral obesity, the metabolic syndrome, androgens and estrogens Aging Male 2006, 9 (2) 75-9
    • (2006) Aging Male , vol.9 , Issue.2 , pp. 75-79
    • Gooren, L.1
  • 8
    • 15744387573 scopus 로고    scopus 로고
    • Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men
    • Wang, Y.; Rimm, E. B.; Stampfer, M. J.; Willett, W. C.; Hu, F. B. Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men Am. J. Clin. Nutr. 2005, 81 (3) 555-63
    • (2005) Am. J. Clin. Nutr. , vol.81 , Issue.3 , pp. 555-563
    • Wang, Y.1    Rimm, E.B.2    Stampfer, M.J.3    Willett, W.C.4    Hu, F.B.5
  • 9
    • 84867806173 scopus 로고    scopus 로고
    • Prognostic implications for insulin-sensitive and insulin-resistant normal-weight and obese individuals from a population-based cohort
    • Bo, S.; Musso, G.; Gambino, R.; Villois, P.; Gentile, L.; Durazzo, M.; Cavallo-Perin, P.; Cassader, M. Prognostic implications for insulin-sensitive and insulin-resistant normal-weight and obese individuals from a population-based cohort Am. J. Clin. Nutr. 2012, 96 (5) 962-9
    • (2012) Am. J. Clin. Nutr. , vol.96 , Issue.5 , pp. 962-969
    • Bo, S.1    Musso, G.2    Gambino, R.3    Villois, P.4    Gentile, L.5    Durazzo, M.6    Cavallo-Perin, P.7    Cassader, M.8
  • 10
    • 84872271216 scopus 로고    scopus 로고
    • Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: A need for screening tools to target interventions
    • DeBoer, M. D. Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: a need for screening tools to target interventions Nutrition 2013, 29 (2) 379-86
    • (2013) Nutrition , vol.29 , Issue.2 , pp. 379-386
    • Deboer, M.D.1
  • 11
    • 84878469610 scopus 로고    scopus 로고
    • Link between obesity and cancer
    • Williams, S. C. Link between obesity and cancer Proc. Natl. Acad. Sci. U. S. A. 2013, 110 (22) 8753-4
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , Issue.22 , pp. 8753-8754
    • Williams, S.C.1
  • 14
    • 84875826371 scopus 로고    scopus 로고
    • The human gut microbiome and body metabolism: Implications for obesity and diabetes
    • Devaraj, S.; Hemarajata, P.; Versalovic, J. The human gut microbiome and body metabolism: implications for obesity and diabetes Clin. Chem. 2013, 59 (4) 617-28
    • (2013) Clin. Chem. , vol.59 , Issue.4 , pp. 617-628
    • Devaraj, S.1    Hemarajata, P.2    Versalovic, J.3
  • 15
    • 70349484669 scopus 로고    scopus 로고
    • Mechanisms of obesity and related pathology: Linking immune responses to metabolic stress
    • Karalis, K. P.; Giannogonas, P.; Kodela, E.; Koutmani, Y.; Zoumakis, M.; Teli, T. Mechanisms of obesity and related pathology: linking immune responses to metabolic stress FEBS J. 2009, 276 (20) 5747-54
    • (2009) FEBS J. , vol.276 , Issue.20 , pp. 5747-5754
    • Karalis, K.P.1    Giannogonas, P.2    Kodela, E.3    Koutmani, Y.4    Zoumakis, M.5    Teli, T.6
  • 16
    • 59649109958 scopus 로고    scopus 로고
    • Shaping the stress response: Interplay of palatable food choices, glucocorticoids, insulin and abdominal obesity
    • Warne, J. P. Shaping the stress response: interplay of palatable food choices, glucocorticoids, insulin and abdominal obesity Mol. Cell. Endocrinol. 2009, 300 (1-2) 137-46
    • (2009) Mol. Cell. Endocrinol. , vol.300 , Issue.12 , pp. 137-146
    • Warne, J.P.1
  • 17
    • 37349020115 scopus 로고    scopus 로고
    • How growth hormone controls growth, obesity and sexual dimorphism
    • Lichanska, A. M.; Waters, M. J. How growth hormone controls growth, obesity and sexual dimorphism Trends Genet. 2008, 24 (1) 41-7
    • (2008) Trends Genet. , vol.24 , Issue.1 , pp. 41-47
    • Lichanska, A.M.1    Waters, M.J.2
  • 18
    • 34548486232 scopus 로고    scopus 로고
    • Resistance to high-fat-diet-induced obesity and sexual dimorphism in the metabolic responses of transgenic mice with moderate uncoupling protein 3 overexpression in glycolytic skeletal muscles
    • Tiraby, C.; Tavernier, G.; Capel, F.; Mairal, A.; Crampes, F.; Rami, J.; Pujol, C.; Boutin, J. A.; Langin, D. Resistance to high-fat-diet-induced obesity and sexual dimorphism in the metabolic responses of transgenic mice with moderate uncoupling protein 3 overexpression in glycolytic skeletal muscles Diabetologia 2007, 50 (10) 2190-9
    • (2007) Diabetologia , vol.50 , Issue.10 , pp. 2190-2199
    • Tiraby, C.1    Tavernier, G.2    Capel, F.3    Mairal, A.4    Crampes, F.5    Rami, J.6    Pujol, C.7    Boutin, J.A.8    Langin, D.9
  • 20
    • 84879476021 scopus 로고    scopus 로고
    • The apelinergic system: Sexual dimorphism and tissue-specific modulations by obesity and insulin resistance in female mice
    • Butruille, L.; Drougard, A.; Knauf, C.; Moitrot, E.; Valet, P.; Storme, L.; Deruelle, P.; Lesage, J. The apelinergic system: sexual dimorphism and tissue-specific modulations by obesity and insulin resistance in female mice Peptides 2013, 46, 94-101
    • (2013) Peptides , vol.46 , pp. 94-101
    • Butruille, L.1    Drougard, A.2    Knauf, C.3    Moitrot, E.4    Valet, P.5    Storme, L.6    Deruelle, P.7    Lesage, J.8
  • 21
    • 79952116875 scopus 로고    scopus 로고
    • Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence
    • Duma, D.; Collins, J. B.; Chou, J. W.; Cidlowski, J. A. Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence Sci. Signal 2010, 3 (143) ra74
    • (2010) Sci. Signal , vol.3 , Issue.143 , pp. 74
    • Duma, D.1    Collins, J.B.2    Chou, J.W.3    Cidlowski, J.A.4
  • 22
    • 0031020076 scopus 로고    scopus 로고
    • Sexual dimorphism of the human stress response may be due to estradiol-mediated stimulation of hypothalamic corticotropin-releasing hormone synthesis
    • Torpy, D. J.; Papanicolaou, D. A.; Chrousos, G. P. Sexual dimorphism of the human stress response may be due to estradiol-mediated stimulation of hypothalamic corticotropin-releasing hormone synthesis J. Clin. Endocrinol. Metab. 1997, 82 (3) 982
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , Issue.3 , pp. 982
    • Torpy, D.J.1    Papanicolaou, D.A.2    Chrousos, G.P.3
  • 23
    • 77958062011 scopus 로고    scopus 로고
    • Stress and sex versus immunity and inflammation
    • Chrousos, G. P. Stress and sex versus immunity and inflammation Sci. Signal 2010, 3 (143) pe36
    • (2010) Sci. Signal , vol.3 , Issue.143 , pp. 36
    • Chrousos, G.P.1
  • 24
    • 0017642176 scopus 로고
    • Claude Bernards (extended) milieu interieur revisited: Autoregulation of cell and subcell integrity
    • Robin, E. D. Claude Bernards (extended) milieu interieur revisited: autoregulation of cell and subcell integrity Clin Sci. Mol. Med. 1977, 52 (5) 443-8
    • (1977) Clin Sci. Mol. Med. , vol.52 , Issue.5 , pp. 443-448
    • Robin, E.D.1
  • 25
    • 0022527908 scopus 로고
    • The milieu interieur, and regulatory physiology
    • Holmes, F. L.; Bernard, Claude the milieu interieur, and regulatory physiology Hist. Philos. Life Sci. 1986, 8 (1) 3-25
    • (1986) Hist. Philos. Life Sci. , vol.8 , Issue.1 , pp. 3-25
    • Holmes, F.L.1    Bernard, C.2
  • 26
    • 0023286769 scopus 로고
    • The inconstancy of the milieu interieur
    • Morris, B. The inconstancy of the milieu interieur Immunol. Cell Biol. 1987, 65 (Pt 1) 49-55
    • (1987) Immunol. Cell Biol. , vol.65 , Issue.PART 1 , pp. 49-55
    • Morris, B.1
  • 27
    • 0026856382 scopus 로고
    • An odyssey into the milieu interieur: Pondering the enigmas
    • Schrier, R. W. An odyssey into the milieu interieur: pondering the enigmas J. Am. Soc. Nephrol. 1992, 2 (11) 1549-59
    • (1992) J. Am. Soc. Nephrol. , vol.2 , Issue.11 , pp. 1549-1559
    • Schrier, R.W.1
  • 28
    • 66149142254 scopus 로고    scopus 로고
    • Milieu interieur: The search for myocardial arteriogenic signals
    • Millard, R. W.; Wang, Y. Milieu interieur: the search for myocardial arteriogenic signals J. Am. Coll. Cardiol. 2009, 53 (23) 2148-9
    • (2009) J. Am. Coll. Cardiol. , vol.53 , Issue.23 , pp. 2148-2149
    • Millard, R.W.1    Wang, Y.2
  • 29
    • 79952140710 scopus 로고    scopus 로고
    • A novel multidimensional protein identification technology approach combining protein size exclusion prefractionation, peptide zwitterion-ion hydrophilic interaction chromatography, and nano-ultraperformance RP chromatography/nESI-MS2 for the in-depth analysis of the serum proteome and phosphoproteome: Application to clinical sera derived from humans with benign prostate hyperplasia
    • Garbis, S. D.; Roumeliotis, T. I.; Tyritzis, S. I.; Zorpas, K. M.; Pavlakis, K.; Constantinides, C. A. A novel multidimensional protein identification technology approach combining protein size exclusion prefractionation, peptide zwitterion-ion hydrophilic interaction chromatography, and nano-ultraperformance RP chromatography/nESI-MS2 for the in-depth analysis of the serum proteome and phosphoproteome: application to clinical sera derived from humans with benign prostate hyperplasia Anal. Chem. 2011, 83 (3) 708-18
    • (2011) Anal. Chem. , vol.83 , Issue.3 , pp. 708-718
    • Garbis, S.D.1    Roumeliotis, T.I.2    Tyritzis, S.I.3    Zorpas, K.M.4    Pavlakis, K.5    Constantinides, C.A.6
  • 30
    • 41649100689 scopus 로고    scopus 로고
    • Mining the plasma proteome for cancer biomarkers
    • Hanash, S. M.; Pitteri, S. J.; Faca, V. M. Mining the plasma proteome for cancer biomarkers Nature 2008, 452 (7187) 571-9
    • (2008) Nature , vol.452 , Issue.7187 , pp. 571-579
    • Hanash, S.M.1    Pitteri, S.J.2    Faca, V.M.3
  • 31
    • 75749130354 scopus 로고    scopus 로고
    • The clinical plasma proteome: A survey of clinical assays for proteins in plasma and serum
    • Anderson, N. L. The clinical plasma proteome: a survey of clinical assays for proteins in plasma and serum Clin. Chem. 2010, 56 (2) 177-85
    • (2010) Clin. Chem. , vol.56 , Issue.2 , pp. 177-185
    • Anderson, N.L.1
  • 32
    • 34548324770 scopus 로고    scopus 로고
    • Serum and plasma proteomics
    • Issaq, H. J.; Xiao, Z.; Veenstra, T. D. Serum and plasma proteomics Chem. Rev. 2007, 107 (8) 3601-20
    • (2007) Chem. Rev. , vol.107 , Issue.8 , pp. 3601-3620
    • Issaq, H.J.1    Xiao, Z.2    Veenstra, T.D.3
  • 33
    • 84894033166 scopus 로고    scopus 로고
    • Proteomics of human prostate cancer biospecimens: The global, systems-wide perspective for protein markers with potential clinical utility
    • Garbis, S. D.; Townsend, P. A. Proteomics of human prostate cancer biospecimens: the global, systems-wide perspective for protein markers with potential clinical utility Expert Rev. Proteomics 2013, 10 (4) 337-54
    • (2013) Expert Rev. Proteomics , vol.10 , Issue.4 , pp. 337-354
    • Garbis, S.D.1    Townsend, P.A.2
  • 34
    • 84870896177 scopus 로고    scopus 로고
    • Assessment of two immunodepletion methods: Off-target effects and variations in immunodepletion efficiency may confound plasma proteomics
    • Patel, B. B.; Barrero, C. A.; Braverman, A.; Kim, P. D.; Jones, K. A.; Chen, D. E.; Bowler, R. P.; Merali, S.; Kelsen, S. G.; Yeung, A. T. Assessment of two immunodepletion methods: off-target effects and variations in immunodepletion efficiency may confound plasma proteomics J. Proteome Res. 2012, 11 (12) 5947-58
    • (2012) J. Proteome Res. , vol.11 , Issue.12 , pp. 5947-5958
    • Patel, B.B.1    Barrero, C.A.2    Braverman, A.3    Kim, P.D.4    Jones, K.A.5    Chen, D.E.6    Bowler, R.P.7    Merali, S.8    Kelsen, S.G.9    Yeung, A.T.10
  • 36
    • 53049090352 scopus 로고    scopus 로고
    • Search for potential markers for prostate cancer diagnosis, prognosis and treatment in clinical tissue specimens using amine-specific isobaric tagging (iTRAQ) with two-dimensional liquid chromatography and tandem mass spectrometry
    • Garbis, S. D.; Tyritzis, S. I.; Roumeliotis, T.; Zerefos, P.; Giannopoulou, E. G.; Vlahou, A.; Kossida, S.; Diaz, J.; Vourekas, S.; Tamvakopoulos, C.; Pavlakis, K.; Sanoudou, D.; Constantinides, C. A. Search for potential markers for prostate cancer diagnosis, prognosis and treatment in clinical tissue specimens using amine-specific isobaric tagging (iTRAQ) with two-dimensional liquid chromatography and tandem mass spectrometry J. Proteome Res. 2008, 7 (8) 3146-58
    • (2008) J. Proteome Res. , vol.7 , Issue.8 , pp. 3146-3158
    • Garbis, S.D.1    Tyritzis, S.I.2    Roumeliotis, T.3    Zerefos, P.4    Giannopoulou, E.G.5    Vlahou, A.6    Kossida, S.7    Diaz, J.8    Vourekas, S.9    Tamvakopoulos, C.10    Pavlakis, K.11    Sanoudou, D.12    Constantinides, C.A.13
  • 37
    • 53849144620 scopus 로고    scopus 로고
    • Strategies for discovering novel cancer biomarkers through utilization of emerging technologies
    • Kulasingam, V.; Diamandis, E. P. Strategies for discovering novel cancer biomarkers through utilization of emerging technologies Nat. Clin. Pract. Oncol. 2008, 5 (10) 588-99
    • (2008) Nat. Clin. Pract. Oncol. , vol.5 , Issue.10 , pp. 588-599
    • Kulasingam, V.1    Diamandis, E.P.2
  • 38
    • 26844561626 scopus 로고    scopus 로고
    • Effect of immunoaffinity depletion of human serum during proteomic investigations
    • Yocum, A. K.; Yu, K.; Oe, T.; Blair, I. A. Effect of immunoaffinity depletion of human serum during proteomic investigations J. Proteome Res. 2005, 4 (5) 1722-31
    • (2005) J. Proteome Res. , vol.4 , Issue.5 , pp. 1722-1731
    • Yocum, A.K.1    Yu, K.2    Oe, T.3    Blair, I.A.4
  • 39
    • 29544441467 scopus 로고    scopus 로고
    • Albumin depletion of human plasma also removes low abundance proteins including the cytokines
    • Granger, J.; Siddiqui, J.; Copeland, S.; Remick, D. Albumin depletion of human plasma also removes low abundance proteins including the cytokines Proteomics 2005, 5 (18) 4713-8
    • (2005) Proteomics , vol.5 , Issue.18 , pp. 4713-4718
    • Granger, J.1    Siddiqui, J.2    Copeland, S.3    Remick, D.4
  • 40
    • 34249992814 scopus 로고    scopus 로고
    • Investigation of an albumin-enriched fraction of human serum and its albuminome
    • Gundry, R. L.; Fu, Q.; Jelinek, C. A.; Van Eyk, J. E.; Cotter, R. J. Investigation of an albumin-enriched fraction of human serum and its albuminome Proteomics Clin. Appl. 2007, 1 (1) 73-88
    • (2007) Proteomics Clin. Appl. , vol.1 , Issue.1 , pp. 73-88
    • Gundry, R.L.1    Fu, Q.2    Jelinek, C.A.3    Van Eyk, J.E.4    Cotter, R.J.5
  • 41
    • 21144435518 scopus 로고    scopus 로고
    • A rapid screening approach to metabonomics using UPLC and oa-TOF mass spectrometry: Application to age, gender and diurnal variation in normal/Zucker obese rats and black, white and nude mice
    • Plumb, R. S.; Granger, J. H.; Stumpf, C. L.; Johnson, K. A.; Smith, B. W.; Gaulitz, S.; Wilson, I. D.; Castro-Perez, J. A rapid screening approach to metabonomics using UPLC and oa-TOF mass spectrometry: application to age, gender and diurnal variation in normal/Zucker obese rats and black, white and nude mice Analyst 2005, 130 (6) 844-9
    • (2005) Analyst , vol.130 , Issue.6 , pp. 844-849
    • Plumb, R.S.1    Granger, J.H.2    Stumpf, C.L.3    Johnson, K.A.4    Smith, B.W.5    Gaulitz, S.6    Wilson, I.D.7    Castro-Perez, J.8
  • 43
    • 79959274524 scopus 로고    scopus 로고
    • Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (Riyadh cohort 2): A decade of an epidemic
    • Al-Daghri, N. M.; Al-Attas, O. S.; Alokail, M. S.; Alkharfy, K. M.; Yousef, M.; Sabico, S. L.; Chrousos, G. P. Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (Riyadh cohort 2): a decade of an epidemic BMC Med. 2011, 9, 76
    • (2011) BMC Med. , vol.9 , pp. 76
    • Al-Daghri, N.M.1    Al-Attas, O.S.2    Alokail, M.S.3    Alkharfy, K.M.4    Yousef, M.5    Sabico, S.L.6    Chrousos, G.P.7
  • 44
    • 60849109966 scopus 로고    scopus 로고
    • Standard operating procedures for serum and plasma collection: Early detection research network consensus statement standard operating procedure integration working group
    • Tuck, M. K.; Chan, D. W.; Chia, D.; Godwin, A. K.; Grizzle, W. E.; Krueger, K. E.; Rom, W.; Sanda, M.; Sorbara, L.; Stass, S.; Wang, W.; Brenner, D. E. Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration working group J. Proteome Res. 2009, 8 (1) 113-7
    • (2009) J. Proteome Res. , vol.8 , Issue.1 , pp. 113-117
    • Tuck, M.K.1    Chan, D.W.2    Chia, D.3    Godwin, A.K.4    Grizzle, W.E.5    Krueger, K.E.6    Rom, W.7    Sanda, M.8    Sorbara, L.9    Stass, S.10    Wang, W.11    Brenner, D.E.12
  • 45
    • 84877157474 scopus 로고    scopus 로고
    • The shotgun proteomic study of the human ThinPrep cervical smear using iTRAQ mass-tagging and 2D LC-FT-Orbitrap-MS: The detection of the human papillomavirus at the protein level
    • Papachristou, E. K.; Roumeliotis, T. I.; Chrysagi, A.; Trigoni, C.; Charvalos, E.; Townsend, P. A.; Pavlakis, K.; Garbis, S. D. The shotgun proteomic study of the human ThinPrep cervical smear using iTRAQ mass-tagging and 2D LC-FT-Orbitrap-MS: the detection of the human papillomavirus at the protein level J. Proteome Res. 2013, 12 (5) 2078-89
    • (2013) J. Proteome Res. , vol.12 , Issue.5 , pp. 2078-2089
    • Papachristou, E.K.1    Roumeliotis, T.I.2    Chrysagi, A.3    Trigoni, C.4    Charvalos, E.5    Townsend, P.A.6    Pavlakis, K.7    Garbis, S.D.8
  • 46
    • 84875926034 scopus 로고    scopus 로고
    • Pharmacoproteomic study of the natural product Ebenfuran III in DU-145 prostate cancer cells: The quantitative and temporal interrogation of chemically induced cell death at the protein level
    • Roumeliotis, T. I.; Halabalaki, M.; Alexi, X.; Ankrett, D.; Giannopoulou, E.; Skaltsounis, A. L.; Sayan, B. S.; Alexis, M. N.; Townsend, P. A.; Garbis, S. D. Pharmacoproteomic study of the natural product Ebenfuran III in DU-145 prostate cancer cells: The quantitative and temporal interrogation of chemically induced cell death at the protein level J. Proteome Res. 2013, 12, 1591-1603
    • (2013) J. Proteome Res. , vol.12 , pp. 1591-1603
    • Roumeliotis, T.I.1    Halabalaki, M.2    Alexi, X.3    Ankrett, D.4    Giannopoulou, E.5    Skaltsounis, A.L.6    Sayan, B.S.7    Alexis, M.N.8    Townsend, P.A.9    Garbis, S.D.10
  • 48
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da, W.; Sherman, B. T.; Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat. Protoc. 2009, 4 (1) 44-57
    • (2009) Nat. Protoc. , vol.4 , Issue.1 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 49
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang da, W.; Sherman, B. T.; Lempicki, R. A. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists Nucleic Acids Res. 2009, 37 (1) 1-13
    • (2009) Nucleic Acids Res. , vol.37 , Issue.1 , pp. 1-13
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 50
    • 0037433040 scopus 로고    scopus 로고
    • Identifying differentially expressed genes using false discovery rate controlling procedures
    • Reiner, A.; Yekutieli, D.; Benjamini, Y. Identifying differentially expressed genes using false discovery rate controlling procedures Bioinformatics 2003, 19 (3) 368-75
    • (2003) Bioinformatics , vol.19 , Issue.3 , pp. 368-375
    • Reiner, A.1    Yekutieli, D.2    Benjamini, Y.3
  • 53
    • 84873328157 scopus 로고    scopus 로고
    • PRIDE Cluster: Building a consensus of proteomics data
    • Griss, J.; Foster, J. M.; Hermjakob, H.; Vizcaino, J. A. PRIDE Cluster: building a consensus of proteomics data Nat. Methods 2013, 10 (2) 95-6
    • (2013) Nat. Methods , vol.10 , Issue.2 , pp. 95-96
    • Griss, J.1    Foster, J.M.2    Hermjakob, H.3    Vizcaino, J.A.4
  • 54
    • 33745515108 scopus 로고    scopus 로고
    • The Proteomics Identifications Database (PRIDE) and the ProteomExchange Consortium: Making proteomics data accessible
    • Hermjakob, H.; Apweiler, R. The Proteomics Identifications Database (PRIDE) and the ProteomExchange Consortium: making proteomics data accessible Expert Rev. Proteomics 2006, 3 (1) 1-3
    • (2006) Expert Rev. Proteomics , vol.3 , Issue.1 , pp. 1-3
    • Hermjakob, H.1    Apweiler, R.2
  • 57
    • 84859515309 scopus 로고    scopus 로고
    • The multifaceted exosome: Biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities
    • Pant, S.; Hilton, H.; Burczynski, M. E. The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities Biochem. Pharmacol. 2012, 83 (11) 1484-94
    • (2012) Biochem. Pharmacol. , vol.83 , Issue.11 , pp. 1484-1494
    • Pant, S.1    Hilton, H.2    Burczynski, M.E.3
  • 59
    • 79951635872 scopus 로고    scopus 로고
    • Improved precision of iTRAQ and TMT quantification by an axial extraction field in an Orbitrap HCD cell
    • Pichler, P.; Kocher, T.; Holzmann, J.; Mohring, T.; Ammerer, G.; Mechtler, K. Improved precision of iTRAQ and TMT quantification by an axial extraction field in an Orbitrap HCD cell Anal. Chem. 2011, 83 (4) 1469-74
    • (2011) Anal. Chem. , vol.83 , Issue.4 , pp. 1469-1474
    • Pichler, P.1    Kocher, T.2    Holzmann, J.3    Mohring, T.4    Ammerer, G.5    Mechtler, K.6
  • 60
    • 80052213520 scopus 로고    scopus 로고
    • TiO2-ZrO2 affinity chromatography polymeric microchip for phosphopeptide enrichment and separation
    • Tsougeni, K.; Zerefos, P.; Tserepi, A.; Vlahou, A.; Garbis, S. D.; Gogolides, E. TiO2-ZrO2 affinity chromatography polymeric microchip for phosphopeptide enrichment and separation Lab Chip 2011, 11 (18) 3113-20
    • (2011) Lab Chip , vol.11 , Issue.18 , pp. 3113-3120
    • Tsougeni, K.1    Zerefos, P.2    Tserepi, A.3    Vlahou, A.4    Garbis, S.D.5    Gogolides, E.6
  • 62
    • 34648846030 scopus 로고    scopus 로고
    • Glucocorticoid and sex hormone receptors: Clinical implications and therapeutic relevance
    • viii
    • Stefanaki, C.; Chrousos, G. P.; Katsambas, A. Glucocorticoid and sex hormone receptors: clinical implications and therapeutic relevance Dermatol. Clin. 2007, 25 (4) 503-13 viii.
    • (2007) Dermatol. Clin. , vol.25 , Issue.4 , pp. 503-513
    • Stefanaki, C.1    Chrousos, G.P.2    Katsambas, A.3
  • 63
    • 77957718168 scopus 로고    scopus 로고
    • Serum pattern profiling for analyzing different types of stress by protein chip technology: A preliminary study
    • Liu, H.; Hou, D.; Wu, D.; Yin, H.; Wu, X. Serum pattern profiling for analyzing different types of stress by protein chip technology: a preliminary study Eur. J. Mass Spectrom. (Chichester, Eng) 2010, 16 (5) 619-23
    • (2010) Eur. J. Mass Spectrom. (Chichester, Eng) , vol.16 , Issue.5 , pp. 619-623
    • Liu, H.1    Hou, D.2    Wu, D.3    Yin, H.4    Wu, X.5
  • 64
    • 84900526349 scopus 로고    scopus 로고
    • Policy: NIH to balance sex in cell and animal studies
    • Clayton, J. A.; Collins, F. S. Policy: NIH to balance sex in cell and animal studies Nature 2014, 509 (7500) 282-3
    • (2014) Nature , vol.509 , Issue.7500 , pp. 282-283
    • Clayton, J.A.1    Collins, F.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.