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Volumn 90, Issue , 2014, Pages 44-52

Acquired resistance to selective estrogen receptor modulators (SERMs) in clinical practice (tamoxifen & raloxifene) by selection pressure in breast cancer cell populations

Author keywords

Estrogen; Estrogen induced apoptosis; Resistance; Selective estrogen receptor modulator (SERM)

Indexed keywords

ESTROGEN; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN;

EID: 84908703414     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2014.06.002     Document Type: Article
Times cited : (29)

References (102)
  • 1
    • 33845929000 scopus 로고    scopus 로고
    • Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer
    • V.C. Jordan, and A.M.H. Brodie Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer Steroids 72 2007 7 25
    • (2007) Steroids , vol.72 , pp. 7-25
    • Jordan, V.C.1    Brodie, A.M.H.2
  • 2
    • 75749092296 scopus 로고    scopus 로고
    • Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen
    • M. Dowsett, J. Cuzick, J. Ingle, A. Coates, J. Forbes, and J. Bliss Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen J Clin Oncol 28 2010 509 518
    • (2010) J Clin Oncol , vol.28 , pp. 509-518
    • Dowsett, M.1    Cuzick, J.2    Ingle, J.3    Coates, A.4    Forbes, J.5    Bliss, J.6
  • 3
    • 33751019459 scopus 로고    scopus 로고
    • Emerging principles for the development of resistance to antihormonal therapy: Implications for the clinical utility of fulvestrant
    • E.A. Ariazi, J.S. Lewis-Wambi, S.D. Gill, J.R. Pyle, J.L. Ariazi, and H.R. Kim Emerging principles for the development of resistance to antihormonal therapy: implications for the clinical utility of fulvestrant J Steroid Biochem Mol Biol 102 2006 128 138
    • (2006) J Steroid Biochem Mol Biol , vol.102 , pp. 128-138
    • Ariazi, E.A.1    Lewis-Wambi, J.S.2    Gill, S.D.3    Pyle, J.R.4    Ariazi, J.L.5    Kim, H.R.6
  • 4
    • 0037102126 scopus 로고    scopus 로고
    • Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: Results of a North American trial
    • C.K. Osborne, J. Pippen, S.E. Jones, L.M. Parker, M. Ellis, and S. Come Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial J Clin Oncol 20 2002 3386 3395
    • (2002) J Clin Oncol , vol.20 , pp. 3386-3395
    • Osborne, C.K.1    Pippen, J.2    Jones, S.E.3    Parker, L.M.4    Ellis, M.5    Come, S.6
  • 5
    • 0037102121 scopus 로고    scopus 로고
    • Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment
    • A. Howell, J.F. Robertson, J. Quaresma Albano, A. Aschermannova, L. Mauriac, and U.R. Kleeberg Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment J Clin Oncol 20 2002 3396 3403
    • (2002) J Clin Oncol , vol.20 , pp. 3396-3403
    • Howell, A.1    Robertson, J.F.2    Quaresma Albano, J.3    Aschermannova, A.4    Mauriac, L.5    Kleeberg, U.R.6
  • 6
    • 0037501319 scopus 로고    scopus 로고
    • The estrogen receptor: A model for molecular medicine
    • E.V. Jensen, and V.C. Jordan The estrogen receptor: a model for molecular medicine Clin Cancer Res 9 2003 1980 1989
    • (2003) Clin Cancer Res , vol.9 , pp. 1980-1989
    • Jensen, E.V.1    Jordan, V.C.2
  • 7
    • 0032537990 scopus 로고    scopus 로고
    • Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
    • B. Fisher, J.P. Costantino, D.L. Wickerham, C.K. Redmond, M. Kavanah, and W.M. Cronin Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study J Natl Cancer Inst 90 1998 1371 1388
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1371-1388
    • Fisher, B.1    Costantino, J.P.2    Wickerham, D.L.3    Redmond, C.K.4    Kavanah, M.5    Cronin, W.M.6
  • 8
    • 37149028451 scopus 로고    scopus 로고
    • Tamoxifen: Catalyst for the change to targeted therapy
    • V.C. Jordan Tamoxifen: catalyst for the change to targeted therapy Eur J Cancer 44 2008 30 38
    • (2008) Eur J Cancer , vol.44 , pp. 30-38
    • Jordan, V.C.1
  • 9
    • 15844425226 scopus 로고    scopus 로고
    • Adjuvant chemotherapy plus tamoxifen compared with tamoxifen alone for postmenopausal breast cancer: Meta-analysis of quality-adjusted survival
    • R.D. Gelber, B.F. Cole, A. Goldhirsch, C. Rose, B. Fisher, and C.K. Osborne Adjuvant chemotherapy plus tamoxifen compared with tamoxifen alone for postmenopausal breast cancer: meta-analysis of quality-adjusted survival Lancet 347 1996 1066 1071
    • (1996) Lancet , vol.347 , pp. 1066-1071
    • Gelber, R.D.1    Cole, B.F.2    Goldhirsch, A.3    Rose, C.4    Fisher, B.5    Osborne, C.K.6
  • 10
    • 19344364880 scopus 로고    scopus 로고
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005; 365: p. 1687-717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 11
    • 85203363507 scopus 로고    scopus 로고
    • Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: Patient-level meta-analysis of randomised trials
    • C. Davies, J. Godwin, R. Gray, M. Clarke, D. Cutter, and S. Darby Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials Lancet 378 2011 771 784
    • (2011) Lancet , vol.378 , pp. 771-784
    • Davies, C.1    Godwin, J.2    Gray, R.3    Clarke, M.4    Cutter, D.5    Darby, S.6
  • 12
    • 0020963216 scopus 로고
    • Laboratory studies to develop general principles for the adjuvant treatment of breast cancer with antiestrogens: Problems and potential for future clinical applications
    • V.C. Jordan Laboratory studies to develop general principles for the adjuvant treatment of breast cancer with antiestrogens: problems and potential for future clinical applications Breast Cancer Res Treat 3 1983 S73 S86
    • (1983) Breast Cancer Res Treat , vol.3 , pp. 73-S86
    • Jordan, V.C.1
  • 13
    • 84908668652 scopus 로고    scopus 로고
    • The aTTom Collaborative Group. ATTom: Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years in 6,953 women with early breast cancer
    • [supplement]
    • The aTTom Collaborative Group. aTTom: Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years in 6,953 women with early breast cancer. J Clin Oncol 2013; 31 [supplement].
    • (2013) J Clin Oncol , vol.31
  • 14
    • 84874745627 scopus 로고    scopus 로고
    • Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial
    • C. Davies, H. Pan, J. Godwin, R. Gray, R. Arriagada, and V. Raina Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial Lancet 381 2013 805 816
    • (2013) Lancet , vol.381 , pp. 805-816
    • Davies, C.1    Pan, H.2    Godwin, J.3    Gray, R.4    Arriagada, R.5    Raina, V.6
  • 15
  • 16
    • 45849109878 scopus 로고    scopus 로고
    • The rise of raloxifene and the fall of invasive breast cancer
    • V.C. Jordan The rise of raloxifene and the fall of invasive breast cancer J Natl Cancer Inst 100 2008 831 833
    • (2008) J Natl Cancer Inst , vol.100 , pp. 831-833
    • Jordan, V.C.1
  • 17
    • 0033575083 scopus 로고    scopus 로고
    • The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial. Multiple outcomes of raloxifene evaluation
    • S.R. Cummings, S. Eckert, K.A. Krueger, D. Grady, T.J. Powles, and J.A. Cauley The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple outcomes of raloxifene evaluation JAMA 281 1999 2189 2197
    • (1999) JAMA , vol.281 , pp. 2189-2197
    • Cummings, S.R.1    Eckert, S.2    Krueger, K.A.3    Grady, D.4    Powles, T.J.5    Cauley, J.A.6
  • 18
    • 0033581212 scopus 로고    scopus 로고
    • Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: Results from a 3-year randomized clinical trial Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators
    • B. Ettinger, D.M. Black, B.H. Mitlak, R.K. Knickerbocker, T. Nickelsen, and H.K. Genant Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators JAMA 282 1999 637 645
    • (1999) JAMA , vol.282 , pp. 637-645
    • Ettinger, B.1    Black, D.M.2    Mitlak, B.H.3    Knickerbocker, R.K.4    Nickelsen, T.5    Genant, H.K.6
  • 19
    • 33745249570 scopus 로고    scopus 로고
    • The study of tamoxifen and raloxifene (STAR): Report of the National Surgical Adjuvant Breast and Bowel Project P-2 Trial
    • V.G. Vogel, J.P. Costantino, D.L. Wickerham, W.M. Cronin, R.S. Cecchini, and J.N. Atkins The study of tamoxifen and raloxifene (STAR): Report of the National Surgical Adjuvant Breast and Bowel Project P-2 Trial JAMA 295 2006 2727 2741
    • (2006) JAMA , vol.295 , pp. 2727-2741
    • Vogel, V.G.1    Costantino, J.P.2    Wickerham, D.L.3    Cronin, W.M.4    Cecchini, R.S.5    Atkins, J.N.6
  • 20
    • 77953529620 scopus 로고    scopus 로고
    • Update of the National Surgical Adjuvant Breast and Bowel Project Study of tamoxifen and raloxifene (STAR) P-2 Trial: Preventing breast cancer
    • V.G. Vogel, J.P. Costantino, D.L. Wickerham, W.M. Cronin, R.S. Cecchini, and J.N. Atkins Update of the National Surgical Adjuvant Breast and Bowel Project Study of tamoxifen and raloxifene (STAR) P-2 Trial: preventing breast cancer Cancer Prev Res 3 2010 696 706
    • (2010) Cancer Prev Res , vol.3 , pp. 696-706
    • Vogel, V.G.1    Costantino, J.P.2    Wickerham, D.L.3    Cronin, W.M.4    Cecchini, R.S.5    Atkins, J.N.6
  • 21
    • 84914107396 scopus 로고    scopus 로고
    • A(nother) scientific strategy to prevent breast cancer in postmenopausal women by enhancing estrogen-induced apoptosis?
    • [Epub ahead of print]
    • Jordan VC. A(nother) scientific strategy to prevent breast cancer in postmenopausal women by enhancing estrogen-induced apoptosis? Menopause 2014; [Epub ahead of print].
    • (2014) Menopause
    • Jordan, V.C.1
  • 22
    • 84900133083 scopus 로고    scopus 로고
    • Changes in bone mineral density are correlated with bone markers and reductions in hot flush severity in postmenopausal women treated with bazedoxifene/conjugated estrogens
    • J.C. Gallagher, H. Shi, S. Mirkin, and A.A. Chines Changes in bone mineral density are correlated with bone markers and reductions in hot flush severity in postmenopausal women treated with bazedoxifene/conjugated estrogens Menopause 20 2013 1126 1132
    • (2013) Menopause , vol.20 , pp. 1126-1132
    • Gallagher, J.C.1    Shi, H.2    Mirkin, S.3    Chines, A.A.4
  • 23
    • 30444434216 scopus 로고    scopus 로고
    • Tamoxifen (ICI 46,474) as a targeted therapy to treat and prevent breast cancer
    • V.C. Jordan Tamoxifen (ICI 46,474) as a targeted therapy to treat and prevent breast cancer Br J Pharmacol 147 2006 S269 S276
    • (2006) Br J Pharmacol , vol.147 , pp. 269-S276
    • Jordan, V.C.1
  • 24
    • 0025338591 scopus 로고
    • Development of antiestrogens and their use in breast cancer: Eighth Cain memorial award lecture
    • L.J. Lerner, and V.C. Jordan Development of antiestrogens and their use in breast cancer: eighth Cain memorial award lecture Cancer Res 50 1990 4177 4189
    • (1990) Cancer Res , vol.50 , pp. 4177-4189
    • Lerner, L.J.1    Jordan, V.C.2
  • 25
    • 33947714587 scopus 로고    scopus 로고
    • SERMs: Meeting the promise of multifunctional medicines
    • V.C. Jordan SERMs: meeting the promise of multifunctional medicines J Natl Cancer Inst 99 2007 350 356
    • (2007) J Natl Cancer Inst , vol.99 , pp. 350-356
    • Jordan, V.C.1
  • 29
    • 0023915865 scopus 로고
    • Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse
    • M.M. Gottardis, S.P. Robinson, P.G. Satyaswaroop, and V.C. Jordan Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse Cancer Res 48 1988 812 815
    • (1988) Cancer Res , vol.48 , pp. 812-815
    • Gottardis, M.M.1    Robinson, S.P.2    Satyaswaroop, P.G.3    Jordan, V.C.4
  • 30
    • 0025300620 scopus 로고
    • Effect of steroidal and nonsteroidal antiestrogens on the growth of a tamoxifen-stimu lated human endometrial carcinoma (EnCa101) in athymic mice
    • M.M. Gottardis, M.E. Ricchio, P.G. Satyaswaroop, and V.C. Jordan Effect of steroidal and nonsteroidal antiestrogens on the growth of a tamoxifen-stimu lated human endometrial carcinoma (EnCa101) in athymic mice Cancer Res 50 1990 3189 3192
    • (1990) Cancer Res , vol.50 , pp. 3189-3192
    • Gottardis, M.M.1    Ricchio, M.E.2    Satyaswaroop, P.G.3    Jordan, V.C.4
  • 32
    • 84875503848 scopus 로고    scopus 로고
    • Effects of bazedoxifene/conjugated estrogens on endometrial safety and bone in postmenopausal women
    • S. Mirkin, B.S. Komm, K. Pan, and A.A. Chines Effects of bazedoxifene/conjugated estrogens on endometrial safety and bone in postmenopausal women Climacteric 16 2013 338 346
    • (2013) Climacteric , vol.16 , pp. 338-346
    • Mirkin, S.1    Komm, B.S.2    Pan, K.3    Chines, A.A.4
  • 33
    • 0037192501 scopus 로고    scopus 로고
    • Molecular determinants for the tissue specificity of SERMs
    • Y. Shang, and M. Brown Molecular determinants for the tissue specificity of SERMs Science 295 2002 2465 2468
    • (2002) Science , vol.295 , pp. 2465-2468
    • Shang, Y.1    Brown, M.2
  • 34
    • 0028846193 scopus 로고
    • Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
    • S.A. Onate, S.Y. Tsai, M.J. Tsai, and B.W. O'Malley Sequence and characterization of a coactivator for the steroid hormone receptor superfamily Science 270 1995 1354 1357
    • (1995) Science , vol.270 , pp. 1354-1357
    • Onate, S.A.1    Tsai, S.Y.2    Tsai, M.J.3    O'Malley, B.W.4
  • 35
    • 1442351143 scopus 로고    scopus 로고
    • Coregulator function: A key to understanding tissue specificity of selective receptor modulators
    • C.L. Smith, and B.W. O'Malley Coregulator function: a key to understanding tissue specificity of selective receptor modulators Endocr Rev 25 2004 45 71
    • (2004) Endocr Rev , vol.25 , pp. 45-71
    • Smith, C.L.1    O'Malley, B.W.2
  • 36
    • 0033637703 scopus 로고    scopus 로고
    • Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
    • Y. Shang, X. Hu, J. DiRenzo, M.A. Lazar, and M. Brown Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription Cell 103 2000 843 852
    • (2000) Cell , vol.103 , pp. 843-852
    • Shang, Y.1    Hu, X.2    Direnzo, J.3    Lazar, M.A.4    Brown, M.5
  • 37
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/co-activator recognition and the antagonism of this interaction by tamoxifen
    • A.K. Shiau, D. Barstad, P.M. Loria, L. Cheng, P.J. Kushner, and D.A. Agard The structural basis of estrogen receptor/co-activator recognition and the antagonism of this interaction by tamoxifen Cell 95 1998 927 937
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6
  • 40
    • 0034534579 scopus 로고    scopus 로고
    • Temporally distinct and ligand-specific recruitment of nuclear receptor-interacting peptides and cofactors to subnuclear domains containing the estrogen receptor
    • F. Schaufele, C.Y. Chang, W. Liu, J.D. Baxter, S.K. Nordeen, and Y. Wan Temporally distinct and ligand-specific recruitment of nuclear receptor-interacting peptides and cofactors to subnuclear domains containing the estrogen receptor Mol Endocrinol 14 2000 2024 2039
    • (2000) Mol Endocrinol , vol.14 , pp. 2024-2039
    • Schaufele, F.1    Chang, C.Y.2    Liu, W.3    Baxter, J.D.4    Nordeen, S.K.5    Wan, Y.6
  • 41
    • 0036185782 scopus 로고    scopus 로고
    • Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements
    • J.M. Hall, D.P. McDonnell, and K.S. Korach Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements Mol Endocrinol 16 2002 469 486
    • (2002) Mol Endocrinol , vol.16 , pp. 469-486
    • Hall, J.M.1    McDonnell, D.P.2    Korach, K.S.3
  • 42
    • 69249110003 scopus 로고    scopus 로고
    • Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family
    • J. Xu, R.C. Wu, and B.W. O'Malley Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family Nat Rev Cancer 9 2009 615 630
    • (2009) Nat Rev Cancer , vol.9 , pp. 615-630
    • Xu, J.1    Wu, R.C.2    O'Malley, B.W.3
  • 43
    • 84876260390 scopus 로고    scopus 로고
    • Molecular mechanism of action of bisphenol and bisphenol a mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells
    • S. Sengupta, I. Obiorah, P.Y. Maximov, R. Curpan, and V.C. Jordan Molecular mechanism of action of bisphenol and bisphenol a mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells Br J Pharmacol 169 2013 167 178
    • (2013) Br J Pharmacol , vol.169 , pp. 167-178
    • Sengupta, S.1    Obiorah, I.2    Maximov, P.Y.3    Curpan, R.4    Jordan, V.C.5
  • 44
    • 80053199540 scopus 로고    scopus 로고
    • The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1
    • J.S. Lewis-Wambi, H. Kim, R. Curpan, R. Grigg, M.A. Sarker, and V.C. Jordan The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1 Mol Pharmacol 80 2011 610 620
    • (2011) Mol Pharmacol , vol.80 , pp. 610-620
    • Lewis-Wambi, J.S.1    Kim, H.2    Curpan, R.3    Grigg, R.4    Sarker, M.A.5    Jordan, V.C.6
  • 45
    • 84877091558 scopus 로고    scopus 로고
    • Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: Implications for treatment of advanced disease
    • S.E. Wardell, E.R. Nelson, C.A. Chao, and D.P. McDonnell Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: implications for treatment of advanced disease Clin Cancer Res 19 2013 2420 2431
    • (2013) Clin Cancer Res , vol.19 , pp. 2420-2431
    • Wardell, S.E.1    Nelson, E.R.2    Chao, C.A.3    McDonnell, D.P.4
  • 46
    • 37649007431 scopus 로고    scopus 로고
    • Selective estrogen-receptor modulators and antihormonal resistance in breast cancer
    • V.C. Jordan, and B.W. O'Malley Selective estrogen-receptor modulators and antihormonal resistance in breast cancer J Clin Oncol 25 2007 5815 5824
    • (2007) J Clin Oncol , vol.25 , pp. 5815-5824
    • Jordan, V.C.1    O'Malley, B.W.2
  • 47
    • 84897861518 scopus 로고    scopus 로고
    • Prediction of tamoxifen outcome by genetic variation of CYP2D6 in post-menopausal women with early breast cancer
    • H. Brauch, and M. Schwab Prediction of tamoxifen outcome by genetic variation of CYP2D6 in post-menopausal women with early breast cancer Br J Clin Pharmacol 77 2014 695 703
    • (2014) Br J Clin Pharmacol , vol.77 , pp. 695-703
    • Brauch, H.1    Schwab, M.2
  • 48
    • 0028093565 scopus 로고
    • The estrogen receptor from a tamoxifen stimulated MCF-7 tumor variant contains a point mutation in the ligand binding domain
    • D.M. Wolf, and V.C. Jordan The estrogen receptor from a tamoxifen stimulated MCF-7 tumor variant contains a point mutation in the ligand binding domain Breast Cancer Res Treat 31 1994 129 138
    • (1994) Breast Cancer Res Treat , vol.31 , pp. 129-138
    • Wolf, D.M.1    Jordan, V.C.2
  • 49
    • 0028144926 scopus 로고
    • Characterization of tamoxifen stimulated MCF-7 tumor variants grown in athymic mice
    • D.M. Wolf, and V.C. Jordan Characterization of tamoxifen stimulated MCF-7 tumor variants grown in athymic mice Breast Cancer Res Treat 31 1994 117 127
    • (1994) Breast Cancer Res Treat , vol.31 , pp. 117-127
    • Wolf, D.M.1    Jordan, V.C.2
  • 50
    • 0037088656 scopus 로고    scopus 로고
    • Structure-function relationships of the raloxifene-estrogen receptor-alpha complex for regulating transforming growth factor-alpha expression in breast cancer cells
    • H. Liu, W.C. Park, D.J. Bentrem, K.P. McKian, L. Reyes Ade, and J.A. Loweth Structure-function relationships of the raloxifene-estrogen receptor-alpha complex for regulating transforming growth factor-alpha expression in breast cancer cells J Biol Chem 277 2002 9189 9198
    • (2002) J Biol Chem , vol.277 , pp. 9189-9198
    • Liu, H.1    Park, W.C.2    Bentrem, D.J.3    McKian, K.P.4    Reyes Ade, L.5    Loweth, J.A.6
  • 51
    • 0035328727 scopus 로고    scopus 로고
    • Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor alpha complex
    • H. Liu, E.S. Lee, A. Deb Los Reyes, J.W. Zapf, and V.C. Jordan Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor alpha complex Cancer Res 61 2001 3632 3639
    • (2001) Cancer Res , vol.61 , pp. 3632-3639
    • Liu, H.1    Lee, E.S.2    Deb Los Reyes, A.3    Zapf, J.W.4    Jordan, V.C.5
  • 52
    • 0344931629 scopus 로고    scopus 로고
    • The interaction of raloxifene and the active metabolite of the antiestrogen EM-800 (SC 5705) with the human estrogen receptor
    • J.M. Schafer, H. Liu, D.A. Tonetti, and V.C. Jordan The interaction of raloxifene and the active metabolite of the antiestrogen EM-800 (SC 5705) with the human estrogen receptor Cancer Res 59 1999 4308 4313
    • (1999) Cancer Res , vol.59 , pp. 4308-4313
    • Schafer, J.M.1    Liu, H.2    Tonetti, D.A.3    Jordan, V.C.4
  • 53
    • 0031008040 scopus 로고    scopus 로고
    • Estrogenic activity is increased for an antiestrogen by a natural mutation of the estrogen receptor
    • A.S. Levenson, W.H. Catherino, and V.C. Jordan Estrogenic activity is increased for an antiestrogen by a natural mutation of the estrogen receptor J Steroid Biochem Mol Biol 60 1997 261 268
    • (1997) J Steroid Biochem Mol Biol , vol.60 , pp. 261-268
    • Levenson, A.S.1    Catherino, W.H.2    Jordan, V.C.3
  • 54
    • 2642593030 scopus 로고    scopus 로고
    • The key to the antiestrogenic mechanism of raloxifene is amino acid 351 (aspartate) in the estrogen receptor
    • A.S. Levenson, and V.C. Jordan The key to the antiestrogenic mechanism of raloxifene is amino acid 351 (aspartate) in the estrogen receptor Cancer Res 58 1998 1872 1875
    • (1998) Cancer Res , vol.58 , pp. 1872-1875
    • Levenson, A.S.1    Jordan, V.C.2
  • 55
    • 84898717745 scopus 로고    scopus 로고
    • Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer
    • R. Jeselsohn, R. Yelensky, G. Buchwalter, G. Frampton, F. Meric-Bernstam, and A.M. Gonzalez-Angulo Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer Clin Cancer Res 20 2014 1757 1767
    • (2014) Clin Cancer Res , vol.20 , pp. 1757-1767
    • Jeselsohn, R.1    Yelensky, R.2    Buchwalter, G.3    Frampton, G.4    Meric-Bernstam, F.5    Gonzalez-Angulo, A.M.6
  • 56
    • 84890252506 scopus 로고    scopus 로고
    • D538G mutation in estrogen receptor-α: A novel mechanism for acquired endocrine resistance in breast cancer
    • K. Merenbakh-Lamin, N. Ben-Baruch, A. Yeheskel, A. Dvir, L. Soussan-Gutman, and R. Jeselsohn D538G mutation in estrogen receptor-α: a novel mechanism for acquired endocrine resistance in breast cancer Cancer Res 73 2013 6856 6864
    • (2013) Cancer Res , vol.73 , pp. 6856-6864
    • Merenbakh-Lamin, K.1    Ben-Baruch, N.2    Yeheskel, A.3    Dvir, A.4    Soussan-Gutman, L.5    Jeselsohn, R.6
  • 57
    • 84884559238 scopus 로고    scopus 로고
    • Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts
    • S. Li, D. Shen, J. Shao, R. Crowder, W. Liu, and A. Prat Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts Cell Rep 4 2013 1116 1130
    • (2013) Cell Rep , vol.4 , pp. 1116-1130
    • Li, S.1    Shen, D.2    Shao, J.3    Crowder, R.4    Liu, W.5    Prat, A.6
  • 58
    • 84888381937 scopus 로고    scopus 로고
    • Activating ESR1 mutations in hormone-resistant metastatic breast cancer
    • D.R. Robinson, Y.M. Wu, P. Vats, F. Su, R.J. Lonigro, and X. Cao Activating ESR1 mutations in hormone-resistant metastatic breast cancer Nat Genet 45 2013 1446 1451
    • (2013) Nat Genet , vol.45 , pp. 1446-1451
    • Robinson, D.R.1    Wu, Y.M.2    Vats, P.3    Su, F.4    Lonigro, R.J.5    Cao, X.6
  • 59
    • 84888391516 scopus 로고    scopus 로고
    • ESR1 ligand-binding domain mutations in hormone-resistant breast cancer
    • W. Toy, Y. Shen, H. Won, B. Green, R.A. Sakr, and M. Will ESR1 ligand-binding domain mutations in hormone-resistant breast cancer Nat Genet 45 2013 1439 1445
    • (2013) Nat Genet , vol.45 , pp. 1439-1445
    • Toy, W.1    Shen, Y.2    Won, H.3    Green, B.4    Sakr, R.A.5    Will, M.6
  • 60
    • 0023760993 scopus 로고
    • Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration
    • M.M. Gottardis, and V.C. Jordan Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration Cancer Res 48 1988 5183 5187
    • (1988) Cancer Res , vol.48 , pp. 5183-5187
    • Gottardis, M.M.1    Jordan, V.C.2
  • 61
    • 0024316533 scopus 로고
    • Differential ability of antiestrogens to stimulate breast cancer cell (MCF-7) growth in vivo and in vitro
    • M.M. Gottardis, R.J. Wagner, E.C. Borden, and V.C. Jordan Differential ability of antiestrogens to stimulate breast cancer cell (MCF-7) growth in vivo and in vitro Cancer Res 49 1989 4765 4769
    • (1989) Cancer Res , vol.49 , pp. 4765-4769
    • Gottardis, M.M.1    Wagner, R.J.2    Borden, E.C.3    Jordan, V.C.4
  • 62
    • 0034066141 scopus 로고    scopus 로고
    • Antitumor action of physiological estradiol on tamoxifen-stimulated breast tumors grown in athymic mice
    • K. Yao, E.S. Lee, D.J. Bentrem, G. England, J.I. Schafer, and R.M. O'Regan Antitumor action of physiological estradiol on tamoxifen-stimulated breast tumors grown in athymic mice Clin Cancer Res 6 2000 2028 2036
    • (2000) Clin Cancer Res , vol.6 , pp. 2028-2036
    • Yao, K.1    Lee, E.S.2    Bentrem, D.J.3    England, G.4    Schafer, J.I.5    O'Regan, R.M.6
  • 63
    • 0024319781 scopus 로고
    • Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens
    • M.M. Gottardis, S.Y. Jiang, M.H. Jeng, and V.C. Jordan Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens Cancer Res 49 1989 4090 4093
    • (1989) Cancer Res , vol.49 , pp. 4090-4093
    • Gottardis, M.M.1    Jiang, S.Y.2    Jeng, M.H.3    Jordan, V.C.4
  • 64
    • 0034490211 scopus 로고    scopus 로고
    • Cross-resistance of triphenylethylene-type antiestrogens but not ICI 182,780 in tamoxifen-stimulated breast tumors grown in athymic mice
    • E.S. Lee, J.M. Schafer, K. Yao, G. England, R.M. O'Regan, and A. De Los Reyes Cross-resistance of triphenylethylene-type antiestrogens but not ICI 182,780 in tamoxifen-stimulated breast tumors grown in athymic mice Clin Cancer Res 6 2000 4893 4899
    • (2000) Clin Cancer Res , vol.6 , pp. 4893-4899
    • Lee, E.S.1    Schafer, J.M.2    Yao, K.3    England, G.4    O'Regan, R.M.5    De Los Reyes, A.6
  • 65
    • 1642544604 scopus 로고    scopus 로고
    • Selective estrogen receptor modulation: Concept and consequences in cancer
    • V.C. Jordan Selective estrogen receptor modulation: concept and consequences in cancer Cancer Cell 5 2004 207 213
    • (2004) Cancer Cell , vol.5 , pp. 207-213
    • Jordan, V.C.1
  • 66
    • 0027357258 scopus 로고
    • A laboratory model to explain the survival advantage observed in patients taking adjuvant tamoxifen therapy
    • D.M. Wolf, and V.C. Jordan A laboratory model to explain the survival advantage observed in patients taking adjuvant tamoxifen therapy Recent Results Cancer Res 127 1993 23 33
    • (1993) Recent Results Cancer Res , vol.127 , pp. 23-33
    • Wolf, D.M.1    Jordan, V.C.2
  • 67
    • 46449134193 scopus 로고    scopus 로고
    • The 38th David A. Karnofsky Lecture. The paradoxical actions of estrogen in breast cancer: Survival or death?
    • V.C. Jordan The 38th David A. Karnofsky Lecture. The paradoxical actions of estrogen in breast cancer: survival or death? J Clin Oncol 26 2008 3073 3082
    • (2008) J Clin Oncol , vol.26 , pp. 3073-3082
    • Jordan, V.C.1
  • 68
    • 28044447607 scopus 로고    scopus 로고
    • The apoptotic action of estrogen following exhaustive antihormonal therapy: A new clinical treatment strategy
    • V.C. Jordan, J.S. Lewis, C. Osipo, and D. Cheng The apoptotic action of estrogen following exhaustive antihormonal therapy: a new clinical treatment strategy Breast 14 2005 624 630
    • (2005) Breast , vol.14 , pp. 624-630
    • Jordan, V.C.1    Lewis, J.S.2    Osipo, C.3    Cheng, D.4
  • 69
    • 0034891355 scopus 로고    scopus 로고
    • High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine therapy
    • P.E. Lønning, P.D. Taylor, G. Anker, J. Iddon, L. Wie, and L.M. Jørgensen High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine therapy Breast Cancer Res Treat 67 2001 111 116
    • (2001) Breast Cancer Res Treat , vol.67 , pp. 111-116
    • Lønning, P.E.1    Taylor, P.D.2    Anker, G.3    Iddon, J.4    Wie, L.5    Jørgensen, L.M.6
  • 70
    • 68949102467 scopus 로고    scopus 로고
    • Lower-dose vs high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: A phase 2 randomized study
    • M.J. Ellis, F. Gao, F. Dehdashti, D.B. Jeffe, P.K. Marcom, and L.A. Carey Lower-dose vs high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: a phase 2 randomized study JAMA 302 2009 774 780
    • (2009) JAMA , vol.302 , pp. 774-780
    • Ellis, M.J.1    Gao, F.2    Dehdashti, F.3    Jeffe, D.B.4    Marcom, P.K.5    Carey, L.A.6
  • 71
    • 0026768801 scopus 로고
    • Response after withdrawal of tamoxifen and progestogens in advanced breast cancer
    • A. Howell, D.J. Dodwell, H. Anderson, and J. Redford Response after withdrawal of tamoxifen and progestogens in advanced breast cancer Ann Oncol 3 1992 611 617
    • (1992) Ann Oncol , vol.3 , pp. 611-617
    • Howell, A.1    Dodwell, D.J.2    Anderson, H.3    Redford, J.4
  • 72
    • 2542464918 scopus 로고
    • Phenol red in tissue culture media is a weak estrogen: Implications concerning the study of estrogen-responsive cells in culture
    • Y. Berthois, J.A. Katzenellenbogen, and B.S. Katzenellenbogen Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture Proc Natl Acad Sci USA 83 1986 2496 2500
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2496-2500
    • Berthois, Y.1    Katzenellenbogen, J.A.2    Katzenellenbogen, B.S.3
  • 73
    • 0023606475 scopus 로고
    • Adaptation of estrogen-dependent MCF-7 cells to low estrogen (phenol red-free) culture
    • W.V. Welshons, and V.C. Jordan Adaptation of estrogen-dependent MCF-7 cells to low estrogen (phenol red-free) culture Eur J Cancer Clin Oncol 23 1987 1935 1939
    • (1987) Eur J Cancer Clin Oncol , vol.23 , pp. 1935-1939
    • Welshons, W.V.1    Jordan, V.C.2
  • 74
    • 0023199060 scopus 로고
    • Proliferation, hormonal responsiveness, and estrogen receptor content of MCF-7 human breast cancer cells grown in the short-term and long-term absence of estrogens
    • B.S. Katzenellenbogen, K.L. Kendra, M.J. Norman, and Y. Berthois Proliferation, hormonal responsiveness, and estrogen receptor content of MCF-7 human breast cancer cells grown in the short-term and long-term absence of estrogens Cancer Res 47 1987 4355 4360
    • (1987) Cancer Res , vol.47 , pp. 4355-4360
    • Katzenellenbogen, B.S.1    Kendra, K.L.2    Norman, M.J.3    Berthois, Y.4
  • 75
    • 0028853923 scopus 로고
    • Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells
    • S. Masamura, S.J. Santner, D.F. Heitjan, and R.J. Santen Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells J Clin Endocrinol Metab 80 1995 2918 2925
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2918-2925
    • Masamura, S.1    Santner, S.J.2    Heitjan, D.F.3    Santen, R.J.4
  • 76
    • 0036721523 scopus 로고    scopus 로고
    • Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol
    • W. Yue, J.P. Wang, M. Conaway, S. Masamura, Y. Li, and R.J. Santen Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol Endocrinology 143 2002 3221 3229
    • (2002) Endocrinology , vol.143 , pp. 3221-3229
    • Yue, W.1    Wang, J.P.2    Conaway, M.3    Masamura, S.4    Li, Y.5    Santen, R.J.6
  • 77
    • 0035930095 scopus 로고    scopus 로고
    • Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17beta-estradiol
    • R.X. Song, G. Mor, F. Naftolin, R.A. McPherson, J. Song, and Z. Zhang Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17beta-estradiol J Natl Cancer Inst 93 2001 714 723
    • (2001) J Natl Cancer Inst , vol.93 , pp. 714-723
    • Song, R.X.1    Mor, G.2    Naftolin, F.3    McPherson, R.A.4    Song, J.5    Zhang, Z.6
  • 78
    • 84965250913 scopus 로고
    • Influence of synthetic oestrogens upon advanced malignant disease
    • A. Haddow, J.M. Watkinson, E. Paterson, and P.C. Koller Influence of synthetic oestrogens upon advanced malignant disease BMJ 23 1944 393 398
    • (1944) BMJ , vol.23 , pp. 393-398
    • Haddow, A.1    Watkinson, J.M.2    Paterson, E.3    Koller, P.C.4
  • 79
    • 0037036684 scopus 로고    scopus 로고
    • Re: Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17 beta-estradiol and the two faces of Janus: Sex steroids as mediators of both cell proliferation and cell death
    • V.C. Jordan, H. Liu, and R. Dardes Re: Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17 beta-estradiol and the two faces of Janus: sex steroids as mediators of both cell proliferation and cell death J Natl Cancer Inst 94 2002 1173
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1173
    • Jordan, V.C.1    Liu, H.2    Dardes, R.3
  • 80
    • 0026460218 scopus 로고
    • An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol
    • S.Y. Jiang, D.M. Wolf, J.M. Yingling, C. Chang, and V.C. Jordan An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol Mol Cell Endocrinol 90 1992 77 86
    • (1992) Mol Cell Endocrinol , vol.90 , pp. 77-86
    • Jiang, S.Y.1    Wolf, D.M.2    Yingling, J.M.3    Chang, C.4    Jordan, V.C.5
  • 81
    • 0029041374 scopus 로고
    • An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein
    • J.J. Pink, S.Y. Jiang, M. Fritsch, and V.C. Jordan An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein Cancer Res 55 1995 2583 2590
    • (1995) Cancer Res , vol.55 , pp. 2583-2590
    • Pink, J.J.1    Jiang, S.Y.2    Fritsch, M.3    Jordan, V.C.4
  • 82
    • 63849267401 scopus 로고    scopus 로고
    • Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis
    • J.S. Lewis-Wambi, H.R. Kim, C. Wambi, R. Patel, J.R. Pyle, and A.J. Klein-Szanto Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis Breast Cancer Res 10 2008 R104
    • (2008) Breast Cancer Res , vol.10 , pp. 104
    • Lewis-Wambi, J.S.1    Kim, H.R.2    Wambi, C.3    Patel, R.4    Pyle, J.R.5    Klein-Szanto, A.J.6
  • 83
    • 62949186374 scopus 로고    scopus 로고
    • Potential of l-buthionine sulfoximine to enhance the apoptotic action of estradiol to reverse acquired antihormonal resistance in metastatic breast cancer
    • J.S. Lewis-Wambi, R. Swaby, H. Kim, and V.C. Jordan Potential of l-buthionine sulfoximine to enhance the apoptotic action of estradiol to reverse acquired antihormonal resistance in metastatic breast cancer J Steroid Biochem Mol Biol 114 2009 33 39
    • (2009) J Steroid Biochem Mol Biol , vol.114 , pp. 33-39
    • Lewis-Wambi, J.S.1    Swaby, R.2    Kim, H.3    Jordan, V.C.4
  • 84
    • 84899046603 scopus 로고    scopus 로고
    • Mechanisms underlying differential response to estrogen-induced apoptosis in long-term estrogen-deprived breast cancer cells
    • E.E. Sweeney, P. Fan, and V.C. Jordan Mechanisms underlying differential response to estrogen-induced apoptosis in long-term estrogen-deprived breast cancer cells Int J Oncol 44 2014 1529 1538
    • (2014) Int J Oncol , vol.44 , pp. 1529-1538
    • Sweeney, E.E.1    Fan, P.2    Jordan, V.C.3
  • 85
    • 18144364655 scopus 로고    scopus 로고
    • Estrogen-induced apoptosis in a breast cancer model resistant to long-term estrogen withdrawal
    • J.S. Lewis, C. Osipo, K. Meeke, and V.C. Jordan Estrogen-induced apoptosis in a breast cancer model resistant to long-term estrogen withdrawal J Steroid Biochem Mol Biol 94 2005 131 141
    • (2005) J Steroid Biochem Mol Biol , vol.94 , pp. 131-141
    • Lewis, J.S.1    Osipo, C.2    Meeke, K.3    Jordan, V.C.4
  • 86
    • 28944444552 scopus 로고    scopus 로고
    • Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation
    • J.S. Lewis, K. Meeke, C. Osipo, E.A. Ross, N. Kidawi, and T. Li Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation J Natl Cancer Inst 97 2005 1746 1759
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1746-1759
    • Lewis, J.S.1    Meeke, K.2    Osipo, C.3    Ross, E.A.4    Kidawi, N.5    Li, T.6
  • 87
    • 82755168809 scopus 로고    scopus 로고
    • Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time
    • E.A. Ariazi, H.E. Cunliffe, J.S. Lewis-Wambi, M.J. Slifker, A.L. Willis, and P. Ramos Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time Proc Natl Acad Sci USA 108 2011 18879 18886
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 18879-18886
    • Ariazi, E.A.1    Cunliffe, H.E.2    Lewis-Wambi, J.S.3    Slifker, M.J.4    Willis, A.L.5    Ramos, P.6
  • 88
    • 0344742233 scopus 로고    scopus 로고
    • Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancer
    • C. Osipo, C. Gajdos, H. Liu, B. Chen, and V.C. Jordan Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancer J Natl Cancer Inst 95 2003 1597 1608
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1597-1608
    • Osipo, C.1    Gajdos, C.2    Liu, H.3    Chen, B.4    Jordan, V.C.5
  • 89
    • 0345604400 scopus 로고    scopus 로고
    • Apoptotic action of 17beta-estradiol in raloxifene-resistant MCF-7 cells in vitro and in vivo
    • H. Liu, E.S. Lee, C. Gajdos, S.T. Pearce, B. Chen, and C. Osipo Apoptotic action of 17beta-estradiol in raloxifene-resistant MCF-7 cells in vitro and in vivo J Natl Cancer Inst 95 2003 1586 1597
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1586-1597
    • Liu, H.1    Lee, E.S.2    Gajdos, C.3    Pearce, S.T.4    Chen, B.5    Osipo, C.6
  • 90
    • 34047274789 scopus 로고    scopus 로고
    • Role for HER2/neu and HER3 in fulvestrant-resistant breast cancer
    • C. Osipo, K. Meeke, D. Cheng, A. Weichel, A. Bertucci, and H. Liu Role for HER2/neu and HER3 in fulvestrant-resistant breast cancer Int J Oncol 30 2007 509 520
    • (2007) Int J Oncol , vol.30 , pp. 509-520
    • Osipo, C.1    Meeke, K.2    Cheng, D.3    Weichel, A.4    Bertucci, A.5    Liu, H.6
  • 91
    • 84900436902 scopus 로고    scopus 로고
    • Defining the conformation of the estrogen receptor complex that controls estrogen induced apoptosis in breast cancer
    • I.E. Obiorah, S. Sengupta, R. Curpan, and V.C. Jordan Defining the conformation of the estrogen receptor complex that controls estrogen induced apoptosis in breast cancer Mol Pharmacol 85 2014 789 799
    • (2014) Mol Pharmacol , vol.85 , pp. 789-799
    • Obiorah, I.E.1    Sengupta, S.2    Curpan, R.3    Jordan, V.C.4
  • 92
    • 84896490292 scopus 로고    scopus 로고
    • Delayed triggering of oestrogen induced apoptosis that contrasts with rapid paclitaxel-induced breast cancer cell death
    • Obiorah I, S. Sengupta, P. Fan, and V.C. Jordan Delayed triggering of oestrogen induced apoptosis that contrasts with rapid paclitaxel-induced breast cancer cell death Br J Cancer 110 2014 1488 1496
    • (2014) Br J Cancer , vol.110 , pp. 1488-1496
    • Sengupta, S.1    Fan, P.2    Jordan, V.C.3
  • 93
    • 84876175066 scopus 로고    scopus 로고
    • Scientific rationale for postmenopause delay in the use of conjugated equine estrogens among postmenopausal women that causes reduction in breast cancer incidence and mortality
    • I. Obiorah, and V.C. Jordan Scientific rationale for postmenopause delay in the use of conjugated equine estrogens among postmenopausal women that causes reduction in breast cancer incidence and mortality Menopause 20 2013 372 382
    • (2013) Menopause , vol.20 , pp. 372-382
    • Obiorah, I.1    Jordan, V.C.2
  • 94
    • 84880899869 scopus 로고    scopus 로고
    • C-Src modulates estrogen-induced stress and apoptosis in estrogen-deprived breast cancer cells
    • P. Fan, O.L. Griffith, F.A. Agboke, P. Anur, X. Zou, and R.E. McDaniel C-Src modulates estrogen-induced stress and apoptosis in estrogen-deprived breast cancer cells Cancer Res 73 2013 4510 4520
    • (2013) Cancer Res , vol.73 , pp. 4510-4520
    • Fan, P.1    Griffith, O.L.2    Agboke, F.A.3    Anur, P.4    Zou, X.5    McDaniel, R.E.6
  • 95
    • 84869489330 scopus 로고    scopus 로고
    • Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines
    • P. Fan, R.E. McDaniel, H.R. Kim, D. Clagett, B. Haddad, and V.C. Jordan Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines Eur J Cancer 48 2012 3488 3498
    • (2012) Eur J Cancer , vol.48 , pp. 3488-3498
    • Fan, P.1    McDaniel, R.E.2    Kim, H.R.3    Clagett, D.4    Haddad, B.5    Jordan, V.C.6
  • 96
    • 84891828889 scopus 로고    scopus 로고
    • Inhibition of c-Src blocks oestrogen-induced apoptosis and restores oestrogen-stimulated growth in long-term oestrogen-deprived breast cancer cells
    • P. Fan, F.A. Agboke, R.E. McDaniel, E.E. Sweeney, X. Zou, and K. Creswell Inhibition of c-Src blocks oestrogen-induced apoptosis and restores oestrogen-stimulated growth in long-term oestrogen-deprived breast cancer cells Eur J Cancer 50 2014 457 468
    • (2014) Eur J Cancer , vol.50 , pp. 457-468
    • Fan, P.1    Agboke, F.A.2    McDaniel, R.E.3    Sweeney, E.E.4    Zou, X.5    Creswell, K.6
  • 97
    • 77954148994 scopus 로고    scopus 로고
    • Raloxifene-stimulated experimental breast cancer with the paradoxical actions of estrogen to promote or prevent tumor growth: A unifying concept in anti-hormone resistance
    • G.M. Balaburski, R.C. Dardes, M. Johnson, B. Haddad, F. Zhu, and E.A. Ross Raloxifene-stimulated experimental breast cancer with the paradoxical actions of estrogen to promote or prevent tumor growth: a unifying concept in anti-hormone resistance Int J Oncol 37 2010 387 398
    • (2010) Int J Oncol , vol.37 , pp. 387-398
    • Balaburski, G.M.1    Dardes, R.C.2    Johnson, M.3    Haddad, B.4    Zhu, F.5    Ross, E.A.6
  • 99
    • 38849091433 scopus 로고    scopus 로고
    • Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function
    • S. Massarweh, C.K. Osborne, C.J. Creighton, L. Qin, A. Tsimelzon, and S. Huang Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function Cancer Res 68 2008 826 833
    • (2008) Cancer Res , vol.68 , pp. 826-833
    • Massarweh, S.1    Osborne, C.K.2    Creighton, C.J.3    Qin, L.4    Tsimelzon, A.5    Huang, S.6
  • 100
    • 0037364074 scopus 로고    scopus 로고
    • Tamoxifen: A most unlikely pioneering medicine
    • V.C. Jordan Tamoxifen: a most unlikely pioneering medicine Nat Rev Drug Discov 2 2003 205 213
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 205-213
    • Jordan, V.C.1
  • 101
    • 80051691488 scopus 로고    scopus 로고
    • The St. Gallen Prize Lecture 2011: Evolution of long-term adjuvant anti-hormone therapy: Consequences and opportunities
    • V.C. Jordan, I. Obiorah, P. Fan, H.R. Kim, E. Ariazi, and H. Cunliffe The St. Gallen Prize Lecture 2011: evolution of long-term adjuvant anti-hormone therapy: consequences and opportunities Breast 20 2011 S1 S11
    • (2011) Breast , vol.20 , pp. 1-S11
    • Jordan, V.C.1    Obiorah, I.2    Fan, P.3    Kim, H.R.4    Ariazi, E.5    Cunliffe, H.6
  • 102
    • 60549103920 scopus 로고    scopus 로고
    • A century of deciphering the control mechanisms of sex steroid action in breast and prostate cancer: The origins of targeted therapy and chemoprevention
    • V.C. Jordan A century of deciphering the control mechanisms of sex steroid action in breast and prostate cancer: the origins of targeted therapy and chemoprevention Cancer Res 69 2009 1243 1254
    • (2009) Cancer Res , vol.69 , pp. 1243-1254
    • Jordan, V.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.