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Volumn 9, Issue 6, 2003, Pages 1980-1989

The estrogen receptor: A model for molecular medicine

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; CLOMIFENE; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ETHAMOXYTRIPHETOL; NAFOXIDINE; NONSTEROID ANTIINFLAMMATORY AGENT; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TAMOXIFEN CITRATE;

EID: 0037501319     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (404)

References (95)
  • 1
    • 50549123220 scopus 로고
    • On the treatment of inoperable cases of carcinoma of the mamma: Suggestions for a new method of treatment with illustrative cases
    • Beatson, G. T. On the treatment of inoperable cases of carcinoma of the mamma: suggestions for a new method of treatment with illustrative cases. Lancet, 2: 104-107, 1896.
    • (1896) Lancet , vol.2 , pp. 104-107
    • Beatson, G.T.1
  • 2
    • 0001733527 scopus 로고
    • On oophorectomy in cancer of the breast
    • Boyd, S. On oophorectomy in cancer of the breast. BMJ, 2: 1161-1167, 1900.
    • (1900) BMJ , vol.2 , pp. 1161-1167
    • Boyd, S.1
  • 3
    • 0001561849 scopus 로고
    • Inhibition of human mammary and prostatic cancers by adrenalectomy
    • Huggins, C., and Bergenstal, D. M. Inhibition of human mammary and prostatic cancers by adrenalectomy. Cancer Res., 12: 134-141, 1952.
    • (1952) Cancer Res. , vol.12 , pp. 134-141
    • Huggins, C.1    Bergenstal, D.M.2
  • 4
    • 0001566887 scopus 로고
    • Experiences with hypophysectomy in man
    • Luft, R., and Olivecrona, H. Experiences with hypophysectomy in man. J. Neurosurg., 10: 301-316, 1953.
    • (1953) J. Neurosurg. , vol.10 , pp. 301-316
    • Luft, R.1    Olivecrona, H.2
  • 5
    • 84965250913 scopus 로고
    • Influence of synthetic oestrogens upon advanced malignant disease
    • Haddow, A., Watkinson, J. M., and Paterson, E. Influence of synthetic oestrogens upon advanced malignant disease. BMJ, 2: 393-398, 1944.
    • (1944) BMJ , vol.2 , pp. 393-398
    • Haddow, A.1    Watkinson, J.M.2    Paterson, E.3
  • 6
    • 84965819865 scopus 로고
    • Further investigations on the origins of tumors in mice III on the part played by internal secretions in the spontaneous development of tumors
    • Lathrop, A. E., and Loeb, L. Further investigations on the origins of tumors in mice III on the part played by internal secretions in the spontaneous development of tumors. J. Cancer Res., 1: 1-19, 1916.
    • (1916) J. Cancer Res. , vol.1 , pp. 1-19
    • Lathrop, A.E.1    Loeb, L.2
  • 7
    • 0000673542 scopus 로고
    • An ovarian hormone: Preliminary report on its localization, extraction and partial purification and action in test animals
    • Allen, E., and Doisy, E. A. An ovarian hormone: preliminary report on its localization, extraction and partial purification and action in test animals. J. Am. Med. Assoc., 81: 819-821, 1923.
    • (1923) J. Am. Med. Assoc. , vol.81 , pp. 819-821
    • Allen, E.1    Doisy, E.A.2
  • 8
    • 84965826780 scopus 로고
    • Hormonal pathogenesis of adenocarcinoma of the breast
    • Lacassagne, A. Hormonal pathogenesis of adenocarcinoma of the breast. Am. J. Cancer, 27: 217-225, 1936.
    • (1936) Am. J. Cancer , vol.27 , pp. 217-225
    • Lacassagne, A.1
  • 9
    • 0002746620 scopus 로고
    • Fate of steroidal estrogens in target tissues
    • G. Pincus and E. P. Vollmer (eds.). New York: Academic Press
    • Jensen, E. V., and Jacobson, H. I. Fate of steroidal estrogens in target tissues. In: G. Pincus and E. P. Vollmer (eds.), Biological Activities of Steroids in Relation to Cancer, pp. 161-174. New York: Academic Press, 1960.
    • (1960) Biological Activities of Steroids in Relation to Cancer , pp. 161-174
    • Jensen, E.V.1    Jacobson, H.I.2
  • 10
    • 0001464486 scopus 로고
    • Basic guides to the mechanism of estrogen action
    • Jensen, E. V., and Jacobson, H. I. Basic guides to the mechanism of estrogen action. Recent Prog. Horm. Res., 18: 318-414, 1962.
    • (1962) Recent Prog. Horm. Res. , vol.18 , pp. 318-414
    • Jensen, E.V.1    Jacobson, H.I.2
  • 11
    • 0013913886 scopus 로고
    • A receptor molecule for estrogens: Isolation from the rat uterus and preliminary characterization
    • Toft, D., and Gorski, J. A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization. Proc. Natl. Acad. Sci. USA, 55: 1574-1581, 1966.
    • (1966) Proc. Natl. Acad. Sci. USA , vol.55 , pp. 1574-1581
    • Toft, D.1    Gorski, J.2
  • 12
    • 0014096121 scopus 로고
    • A receptor molecule for estrogens: Studies using a cell-free system
    • Toft, D., Shyamala, G., and Gorski, J. A receptor molecule for estrogens: studies using a cell-free system. Proc. Natl. Acad. Sci. USA, 57: 1740-1743, 1967.
    • (1967) Proc. Natl. Acad. Sci. USA , vol.57 , pp. 1740-1743
    • Toft, D.1    Shyamala, G.2    Gorski, J.3
  • 14
    • 0015861556 scopus 로고
    • Estrogenic hormone effect transformation of specific receptor proteins to a biochemically functional form
    • Jensen, E. V., and DeSombre, E. R. Estrogenic hormone effect transformation of specific receptor proteins to a biochemically functional form. Science (Wash. DC), 182: 126-134, 1973.
    • (1973) Science (Wash. DC) , vol.182 , pp. 126-134
    • Jensen, E.V.1    DeSombre, E.R.2
  • 16
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau, A. K., Barstad, D., Loria, P. M., Cheng, L., Kushner, P. J., Agard, D. A., and Greene, G. L. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell, 95: 927-937, 1998.
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6    Greene, G.L.7
  • 19
    • 0004648364 scopus 로고
    • Antibodies to estrogen receptor. Immunoclinical similarity of estrophilin from various mammalian species
    • Green, G. L., Closs, L. E., Fleming, H., De Sombre, E. R., and Jensen, E. V. Antibodies to estrogen receptor. Immunoclinical similarity of estrophilin from various mammalian species. Proc. Natl. Acad. Sci. USA, 74: 3681-3685, 1977.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 3681-3685
    • Green, G.L.1    Closs, L.E.2    Fleming, H.3    De Sombre, E.R.4    Jensen, E.V.5
  • 20
    • 0018904999 scopus 로고
    • Monoclonal antibodies to estrophilin: Probes for the study of estrogen receptors
    • Greene, G., Fitch, F. W., and Jensen, E. V. Monoclonal antibodies to estrophilin: probes for the study of estrogen receptors. Proc. Natl. Acad. Sci. USA, 77: 157-161, 1980.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 157-161
    • Greene, G.1    Fitch, F.W.2    Jensen, E.V.3
  • 22
    • 0022517602 scopus 로고
    • Determination of estrogen receptor in breast cancer using monoclonal antibody technology: Results of a multicenter study in the United States
    • Jordan, V. C., Jacobson, H. I., and Keenan, E. J. Determination of estrogen receptor in breast cancer using monoclonal antibody technology: results of a multicenter study in the United States. Cancer Res., 46: 4237s-4240s, 1986.
    • (1986) Cancer Res. , vol.46
    • Jordan, V.C.1    Jacobson, H.I.2    Keenan, E.J.3
  • 24
    • 0021934430 scopus 로고
    • Comparison of immunocytochemical and steroid binding assays for estrogen receptor in human breast tumors
    • King, W. J., DeSombre, E. R., Jensen, E. V., and Green, G. L. Comparison of immunocytochemical and steroid binding assays for estrogen receptor in human breast tumors. Cancer Res., 45: 293-304, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 293-304
    • King, W.J.1    DeSombre, E.R.2    Jensen, E.V.3    Green, G.L.4
  • 25
    • 0015069359 scopus 로고
    • A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474
    • Cole, M. P., Jones, C. T., and Todd, I. D. A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474. Br. J. Cancer, 25: 270-275, 1971.
    • (1971) Br. J. Cancer , vol.25 , pp. 270-275
    • Cole, M.P.1    Jones, C.T.2    Todd, I.D.3
  • 26
    • 0015915672 scopus 로고
    • Anti-oestrogen therapy for breast cancer: A trial of tamoxifen at two dose levels
    • Ward, H. W. Anti-oestrogen therapy for breast cancer: a trial of tamoxifen at two dose levels. Br. Med. J., 1: 13-14, 1973.
    • (1973) Br. Med. J. , vol.1 , pp. 13-14
    • Ward, H.W.1
  • 27
    • 0023773272 scopus 로고
    • The development of tamoxifen for breast cancer therapy: A tribute to the late Arthur L. Walpole
    • Jordan, V. C. The development of tamoxifen for breast cancer therapy: a tribute to the late Arthur L. Walpole. Breast Cancer Res. Treat., 11: 197-209, 1988.
    • (1988) Breast Cancer Res. Treat. , vol.11 , pp. 197-209
    • Jordan, V.C.1
  • 28
    • 0014710806 scopus 로고
    • Postcoital contraception
    • Emmens, C. W. Postcoital contraception. Br. Med. Bull., 26: 45-51. 1970.
    • (1970) Br. Med. Bull. , vol.26 , pp. 45-51
    • Emmens, C.W.1
  • 29
    • 0014132654 scopus 로고
    • The Wm. S. Merrell Company Clomiphene citrate (Clomid). Clin. Pharmacol. Therap., 8: 891-897, 1967.
    • (1967) Clin. Pharmacol. Therap. , vol.8 , pp. 891-897
  • 30
    • 36949059277 scopus 로고
    • Contrasting endocrine activities of cis and trans isomers in a series of substituted triphenylethylenes
    • Harper, M. J., and Walpole, A. L. Contrasting endocrine activities of cis and trans isomers in a series of substituted triphenylethylenes. Nature (Lond.), 212: 87, 1966.
    • (1966) Nature (Lond.) , vol.212 , pp. 87
    • Harper, M.J.1    Walpole, A.L.2
  • 31
    • 0014053604 scopus 로고
    • A new derivative of triphenylethylene: Effect on implantation and mode of action in rats
    • Harper, M. J., and Walpole, A. L. A new derivative of triphenylethylene: effect on implantation and mode of action in rats. J. Reprod. Fertil., 13: 101-119, 1967.
    • (1967) J. Reprod. Fertil. , vol.13 , pp. 101-119
    • Harper, M.J.1    Walpole, A.L.2
  • 32
    • 0014039539 scopus 로고
    • Mode of action of ICI 46,474 in preventing implantation in rats
    • Harper, M. J., and Walpole, A. L. Mode of action of ICI 46,474 in preventing implantation in rats. J. Endocrinol., 37: 83-92, 1967.
    • (1967) J. Endocrinol. , vol.37 , pp. 83-92
    • Harper, M.J.1    Walpole, A.L.2
  • 33
    • 0001761072 scopus 로고
    • Preparation and identification of cis and trans isomers of a substituted triphenylethylene
    • Bedford, G., and Richardson, D. N. Preparation and identification of cis and trans isomers of a substituted triphenylethylene. Nature (Lond.), 212: 733-734, 1966.
    • (1966) Nature (Lond.) , vol.212 , pp. 733-734
    • Bedford, G.1    Richardson, D.N.2
  • 34
    • 0015228433 scopus 로고
    • New synthetic agent for the induction of ovulation. Preliminary trial in women
    • Klopper, A., and Hall, M. New synthetic agent for the induction of ovulation. Preliminary trial in women. Br. Med. J., 1: 152-154, 1971.
    • (1971) Br. Med. J. , vol.1 , pp. 152-154
    • Klopper, A.1    Hall, M.2
  • 35
    • 0015364812 scopus 로고
    • Treatment of menometrorrhagia with antioestrogen
    • El-Sheikha, Z., Klopper, A., and Beck, J. S. Treatment of menometrorrhagia with antioestrogen. Clin. Endocrinol., 1: 275-282, 1972.
    • (1972) Clin. Endocrinol. , vol.1 , pp. 275-282
    • El-Sheikha, Z.1    Klopper, A.2    Beck, J.S.3
  • 38
    • 0000468691 scopus 로고
    • Mammary cancer induced by a single feeding of polynuclear hydrocarbons and their suppression
    • Huggins, C., Grand, L. C., and Brillantes, F. P. Mammary cancer induced by a single feeding of polynuclear hydrocarbons and their suppression. Nature (Lond.), 189: 204, 1961.
    • (1961) Nature (Lond.) , vol.189 , pp. 204
    • Huggins, C.1    Grand, L.C.2    Brillantes, F.P.3
  • 39
    • 0000795850 scopus 로고
    • The role of ovarian hormones in initiating the induction of mammary cancer in rats by polynuclear hydrocarbons
    • Dao, T. L. The role of ovarian hormones in initiating the induction of mammary cancer in rats by polynuclear hydrocarbons. Cancer Res., 22: 973-978, 1962.
    • (1962) Cancer Res. , vol.22 , pp. 973-978
    • Dao, T.L.1
  • 41
    • 0013993396 scopus 로고
    • The uptake of triated oestradiol by dimethylbenzanthracene-induced mammary tumours of the rat
    • Mobbs, B. G. The uptake of triated oestradiol by dimethylbenzanthracene-induced mammary tumours of the rat. J. Endocrinol., 36: 409-414, 1966.
    • (1966) J. Endocrinol. , vol.36 , pp. 409-414
    • Mobbs, B.G.1
  • 42
    • 0015294754 scopus 로고
    • Effect of some triphenylethylenes on oestradiol binding in vitro to macromolecules from uterus and anterior pituitary
    • Skidmore, J. R., Walpole, A. L., and Woodburn, J. Effect of some triphenylethylenes on oestradiol binding in vitro to macromolecules from uterus and anterior pituitary. J. Endocrinol., 52: 289-298, 1972.
    • (1972) J. Endocrinol. , vol.52 , pp. 289-298
    • Skidmore, J.R.1    Walpole, A.L.2    Woodburn, J.3
  • 43
    • 0016424339 scopus 로고
    • Prolonged antioestrogenic activity of ICI 46,474 in the ovariectomized mouse
    • Jordan, V. C. Prolonged antioestrogenic activity of ICI 46,474 in the ovariectomized mouse. J. Reprod. Fertil., 42: 251-258, 1975.
    • (1975) J. Reprod. Fertil. , vol.42 , pp. 251-258
    • Jordan, V.C.1
  • 44
    • 0017152984 scopus 로고
    • Tamoxifen as an antitumour agent: Effect on oestrogen binding
    • Jordan, V. C., and Dowse, L. J. Tamoxifen as an antitumour agent: effect on oestrogen binding. J. Endocrinol., 68: 297-303, 1976.
    • (1976) J. Endocrinol. , vol.68 , pp. 297-303
    • Jordan, V.C.1    Dowse, L.J.2
  • 45
    • 0016638259 scopus 로고
    • Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor
    • Jordan, V. C., and Koerner, S. Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor. Eur. J. Cancer, 11: 205-206, 1975.
    • (1975) Eur. J. Cancer , vol.11 , pp. 205-206
    • Jordan, V.C.1    Koerner, S.2
  • 46
    • 0017098034 scopus 로고
    • Tamoxifen as an antitumour agent: Oestrogen binding as a predictive test for tumour response
    • Jordan, V. C., and Jaspan, T. Tamoxifen as an antitumour agent: oestrogen binding as a predictive test for tumour response. J. Endocrinol., 68: 453-460, 1976.
    • (1976) J. Endocrinol. , vol.68 , pp. 453-460
    • Jordan, V.C.1    Jaspan, T.2
  • 47
    • 0018906517 scopus 로고
    • Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model
    • Jordan, V. C., and Allen, K. E. Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model. Eur. J. Cancer, 16: 239-251, 1980.
    • (1980) Eur. J. Cancer , vol.16 , pp. 239-251
    • Jordan, V.C.1    Allen, K.E.2
  • 48
    • 0002487846 scopus 로고
    • The effectiveness of long term tamoxifen treatment in a laboratory model for adjuvant hormone therapy of breast cancer
    • Jordan, V. C., Dix, C. J., and Allen, K. E. The effectiveness of long term tamoxifen treatment in a laboratory model for adjuvant hormone therapy of breast cancer. Adj. Ther. Cancer, 2: 19-26, 1979.
    • (1979) Adj. Ther. Cancer , vol.2 , pp. 19-26
    • Jordan, V.C.1    Dix, C.J.2    Allen, K.E.3
  • 49
    • 0032537396 scopus 로고    scopus 로고
    • EBCTCG Tamoxifen for early breast cancer: An overview of the randomised trials
    • EBCTCG Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet, 351: 1451-1467, 1998.
    • (1998) Lancet , vol.351 , pp. 1451-1467
  • 50
    • 0001626384 scopus 로고
    • Antitumour activity of the antioestrogen ICI 46,474 (tamoxifen) in the dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma model
    • Jordan, V. C. Antitumour activity of the antioestrogen ICI 46,474 (tamoxifen) in the dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma model. J. Steroid Biochem., 5: 354, 1974.
    • (1974) J. Steroid Biochem. , vol.5 , pp. 354
    • Jordan, V.C.1
  • 51
    • 0017078344 scopus 로고
    • Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata
    • Jordan, V. C. Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata. Eur. J. Cancer, 12: 419-424, 1976.
    • (1976) Eur. J. Cancer , vol.12 , pp. 419-424
    • Jordan, V.C.1
  • 54
    • 0025338591 scopus 로고
    • The development of antiestrogens for the treatment of breast cancer
    • Lerner, L. J., and Jordan, V. C. The development of antiestrogens for the treatment of breast cancer. Cancer Res., 50: 4177-4189, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 4177-4189
    • Lerner, L.J.1    Jordan, V.C.2
  • 56
    • 0007649376 scopus 로고
    • The influence of clomid and its isomers on dimethylbenzanthracene-induced rat mammary tumours
    • Basel: Karger
    • Schulz, K-D., Haselmayer, B., and Holzel, F. The influence of clomid and its isomers on dimethylbenzanthracene-induced rat mammary tumours. In: Basic Actions of Sex Steroids on Target Organs, pp. 274-279. Basel: Karger, 1971.
    • (1971) Basic Actions of Sex Steroids on Target Organs , pp. 274-279
    • Schulz, K.-D.1    Haselmayer, B.2    Holzel, F.3
  • 57
    • 0023547257 scopus 로고
    • Effects of antiestrogens on bone in castrated and intact female rats
    • Jordan, V. C., Phelps, E., and Lindgren, J. U. Effects of antiestrogens on bone in castrated and intact female rats. Breast Cancer Res. Treat., 10: 31-35, 1987.
    • (1987) Breast Cancer Res. Treat. , vol.10 , pp. 31-35
    • Jordan, V.C.1    Phelps, E.2    Lindgren, J.U.3
  • 58
    • 0023229345 scopus 로고
    • Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model
    • Gottardis, M. M., and Jordan, V. C. Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model. Cancer Res., 47: 4020-4024, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 4020-4024
    • Gottardis, M.M.1    Jordan, V.C.2
  • 59
    • 0023930991 scopus 로고
    • Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats
    • Turner, R. T., Wakley, G. K., Hannon, K. S., and Bell. N. H. Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats. Endocrinology, 122: 1146-1150, 1988.
    • (1988) Endocrinology , vol.122 , pp. 1146-1150
    • Turner, R.T.1    Wakley, G.K.2    Hannon, K.S.3    Bell, N.H.4
  • 61
    • 0023915865 scopus 로고
    • Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse
    • Gottardis, M. M., Robinson, S. P., Satyaswaroop, P. G., and Jordan, V. C. Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse. Cancer Res., 48: 812-815, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 812-815
    • Gottardis, M.M.1    Robinson, S.P.2    Satyaswaroop, P.G.3    Jordan, V.C.4
  • 63
    • 0020694796 scopus 로고
    • Antagonism of estrogen action with a new benzothiophene derived antiestrogen
    • Black, L. J., Jones, C. D., and Falcone, J. F. Antagonism of estrogen action with a new benzothiophene derived antiestrogen. Life Sci., 32: 1031-1036, 1983.
    • (1983) Life Sci. , vol.32 , pp. 1031-1036
    • Black, L.J.1    Jones, C.D.2    Falcone, J.F.3
  • 64
    • 0023683229 scopus 로고
    • Phase II evaluation of Ly156758 in metastatic breast cancer
    • Buzdar, A. U., Marcus, C., Holmes, F., Hug, V., and Hortobagyi, G. Phase II evaluation of Ly156758 in metastatic breast cancer. Oncology, 45: 344-345, 1988.
    • (1988) Oncology , vol.45 , pp. 344-345
    • Buzdar, A.U.1    Marcus, C.2    Holmes, F.3    Hug, V.4    Hortobagyi, G.5
  • 67
    • 0027201501 scopus 로고
    • Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats
    • Greaves, P., Goonetilleke, R., Nunn, G., Topham, J., and Orton, T. Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats. Cancer Res., 53: 3919-3924, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 3919-3924
    • Greaves, P.1    Goonetilleke, R.2    Nunn, G.3    Topham, J.4    Orton, T.5
  • 68
    • 0034989609 scopus 로고    scopus 로고
    • Understanding the genotoxicity of tamoxifen?
    • Phillips, D. H. Understanding the genotoxicity of tamoxifen? Carcinogenesis (Lond.), 22: 839-849, 2001.
    • (2001) Carcinogenesis (Lond.) , vol.22 , pp. 839-849
    • Phillips, D.H.1
  • 72
    • 0033533207 scopus 로고    scopus 로고
    • Raloxifene as a multifunctional medicine?
    • Jordan, V. C., and Morrow, M. Raloxifene as a multifunctional medicine? BMJ, 319: 331-332, 1999.
    • (1999) BMJ , vol.319 , pp. 331-332
    • Jordan, V.C.1    Morrow, M.2
  • 73
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women principal results from the women's health initiative randomized controlled trial
    • Writing Group for the Women's Health Initiative Investigators Risks and benefits of estrogen plus progestin in healthy postmenopausal women principal results from the women's health initiative randomized controlled trial. J. Am. Med. Assoc., 288: 321-333, 2002.
    • (2002) J. Am. Med. Assoc. , vol.288 , pp. 321-333
  • 75
    • 0004496862 scopus 로고
    • Adjuvant tamoxifen in the management of operable breast cancer: The Scottish Trial. Report from the Breast Cancer Trials Committee, Scottish Cancer Trials Office (MRC), Edinburgh
    • Adjuvant tamoxifen in the management of operable breast cancer: the Scottish Trial. Report from the Breast Cancer Trials Committee, Scottish Cancer Trials Office (MRC), Edinburgh. Lancet., 2: 171-175, 1987.
    • (1987) Lancet , vol.2 , pp. 171-175
  • 76
    • 0020587401 scopus 로고
    • An estrogen receptor model to describe the regulation of prolactin synthesis by antiestrogens in vitro
    • Lieberman, M. E., Gorski, J., and Jordan, V. C. An estrogen receptor model to describe the regulation of prolactin synthesis by antiestrogens in vitro. J. Biol. Chem., 258: 4741-4745, 1983.
    • (1983) J. Biol. Chem. , vol.258 , pp. 4741-4745
    • Lieberman, M.E.1    Gorski, J.2    Jordan, V.C.3
  • 77
    • 0021365432 scopus 로고
    • Differences between estrogen- and antiestrogen-estrogen receptor complexes from human breast tumors identified with an antibody raised against the estrogen receptor
    • Tate, A. C., Greene, G. L., DeSombre, E. R., Jensen, E. V., and Jordan, V. C. Differences between estrogen- and antiestrogen-estrogen receptor complexes from human breast tumors identified with an antibody raised against the estrogen receptor. Cancer Res., 44: 1012-1018, 1984.
    • (1984) Cancer Res. , vol.44 , pp. 1012-1018
    • Tate, A.C.1    Greene, G.L.2    DeSombre, E.R.3    Jensen, E.V.4    Jordan, V.C.5
  • 78
    • 0020585962 scopus 로고
    • Direct and reversible inhibition of estradiol-stimulated prolactin synthesis by antiestrogens in vitro
    • Lieberman, M. E., Jordan, V. C., Fritsch, M., Santos, M. A., and Gorski, J. Direct and reversible inhibition of estradiol-stimulated prolactin synthesis by antiestrogens in vitro. J. Biol. Chem., 258: 4734-4740, 1983.
    • (1983) J. Biol. Chem. , vol.258 , pp. 4734-4740
    • Lieberman, M.E.1    Jordan, V.C.2    Fritsch, M.3    Santos, M.A.4    Gorski, J.5
  • 79
    • 0023110431 scopus 로고
    • Laboratory models of breast cancer to aid the elucidation of antiestrogen action
    • Jordan, V. C. Laboratory models of breast cancer to aid the elucidation of antiestrogen action. J. Lab. Clin. Med., 109: 267-277, 1987.
    • (1987) J. Lab. Clin. Med. , vol.109 , pp. 267-277
    • Jordan, V.C.1
  • 83
    • 0028093565 scopus 로고
    • The estrogen receptor from a tamoxifen stimulated MCF-7 tumor variant contains a point mutation in the ligand binding domain
    • Wolf, D. M., and Jordan, V. C. The estrogen receptor from a tamoxifen stimulated MCF-7 tumor variant contains a point mutation in the ligand binding domain. Breast Cancer Res. Treat., 31: 129-138, 1994.
    • (1994) Breast Cancer Res. Treat. , vol.31 , pp. 129-138
    • Wolf, D.M.1    Jordan, V.C.2
  • 84
    • 0029154750 scopus 로고
    • A naturally occurring estrogen receptor mutation results in increased estrogenicity of a tamoxifen analog
    • Catherino, W. H., Wolf, D. M., and Jordan, V. C. A naturally occurring estrogen receptor mutation results in increased estrogenicity of a tamoxifen analog. Mol. Endocrinol., 9: 1053-1063, 1995.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 1053-1063
    • Catherino, W.H.1    Wolf, D.M.2    Jordan, V.C.3
  • 85
    • 0031008040 scopus 로고    scopus 로고
    • Estrogenic activity is increased for an antiestrogen by a natural mutation of the estrogen receptor
    • Levenson, A. S., Catherino, W. H., and Jordan, V. C. Estrogenic activity is increased for an antiestrogen by a natural mutation of the estrogen receptor. J. Steroid Biochem. Mol. Biol., 60: 261-268, 1997.
    • (1997) J. Steroid Biochem. Mol. Biol. , vol.60 , pp. 261-268
    • Levenson, A.S.1    Catherino, W.H.2    Jordan, V.C.3
  • 86
    • 2642593030 scopus 로고    scopus 로고
    • The key to the antiestrogenic mechanism of raloxifene is amino acid 351 (aspartate) in the estrogen receptor
    • Levenson, A. S., and Jordan, V. C. The key to the antiestrogenic mechanism of raloxifene is amino acid 351 (aspartate) in the estrogen receptor. Cancer Res., 58: 1872-1875, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 1872-1875
    • Levenson, A.S.1    Jordan, V.C.2
  • 87
    • 0034665358 scopus 로고    scopus 로고
    • Allosteric silencing of activating function 1 in the 4-hydroxytamoxifen estrogen receptor complex by substituting glycine for aspartate at amino acid 351
    • MacGregor-Shafer, J. I., Liu, H., Bentrem, D., Zapf, J., and Jordan, V. C. Allosteric silencing of activating function 1 in the 4-hydroxytamoxifen estrogen receptor complex by substituting glycine for aspartate at amino acid 351. Cancer Res., 60: 5097-5105, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 5097-5105
    • MacGregor-Shafer, J.I.1    Liu, H.2    Bentrem, D.3    Zapf, J.4    Jordan, V.C.5
  • 88
    • 0035328727 scopus 로고    scopus 로고
    • Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor α complex
    • Liu, H., Lee, E. S., De Los Reyes, A., Zapf, J. W., and Jordan, V. C. Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor α complex. Cancer Res., 61: 3632-3639, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 3632-3639
    • Liu, H.1    Lee, E.S.2    De Los Reyes, A.3    Zapf, J.W.4    Jordan, V.C.5
  • 89
    • 0035103201 scopus 로고    scopus 로고
    • Molecular mechanism of action at estrogen receptor alpha of a new clinically relevant antiestrogen (GW7604) related to tamoxifen
    • Bentrem, D., Dardes, R., Liu, H., MacGregor-Schafer, J., Zapf, J., and Jordan, V. Molecular mechanism of action at estrogen receptor alpha of a new clinically relevant antiestrogen (GW7604) related to tamoxifen. Endocrinology, 142: 838-846, 2001.
    • (2001) Endocrinology , vol.142 , pp. 838-846
    • Bentrem, D.1    Dardes, R.2    Liu, H.3    MacGregor-Schafer, J.4    Zapf, J.5    Jordan, V.6
  • 90
    • 0037088656 scopus 로고    scopus 로고
    • Structure-function relationships of the raloxifene-estrogen receptor α complex for regulating transforming growth factor alpha expression in breast cancer cells
    • Liu, H., Park, W., Bentrem, D., McKian, K. P., De Los Reyes, A., MacGregor Schafer, J., Zapf, J., and Jordan, V. C. Structure-function relationships of the raloxifene-estrogen receptor α complex for regulating transforming growth factor alpha expression in breast cancer cells. J. Biol. Chem., 277: 9189-9198, 2002.
    • (2002) J. Biol. Chem. , vol.277 , pp. 9189-9198
    • Liu, H.1    Park, W.2    Bentrem, D.3    McKian, K.P.4    De Los Reyes, A.5    MacGregor Schafer, J.6    Zapf, J.7    Jordan, V.C.8
  • 91
    • 0037435046 scopus 로고    scopus 로고
    • Antiestrogens and selective estrogen receptor modulators as multifunctional medicines part I: Receptor interactions
    • Jordan, V. C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines part I: receptor interactions. J. Med. Chem. 46: 883-908, 2003.
    • (2003) J. Med. Chem. , vol.46 , pp. 883-908
    • Jordan, V.C.1
  • 92
    • 0037621719 scopus 로고    scopus 로고
    • Antiestrogens and selective estrogen receptor modulators as multifunctional medicines part II: Clinical considerations and new agents
    • Jordan, V. C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines part II: clinical considerations and new agents. J. Med. Chem., 46: 1082-1111, 2003.
    • (2003) J. Med. Chem. , vol.46 , pp. 1082-1111
    • Jordan, V.C.1
  • 94
    • 0037102126 scopus 로고    scopus 로고
    • Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: Results of a North American trial
    • Osborne, C. K., Pippen, J., Jones, S. E., Parker, L. M., Ellis, M., Come, S., Gertler, S. Z., May, J. T., Burton, G., Dimery, I., Webster, A., Morris, C., Elledge, R., and Buzdar, A. Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial. J. Clin. Oncol., 20: 3386-3395, 2002.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3386-3395
    • Osborne, C.K.1    Pippen, J.2    Jones, S.E.3    Parker, L.M.4    Ellis, M.5    Come, S.6    Gertler, S.Z.7    May, J.T.8    Burton, G.9    Dimery, I.10    Webster, A.11    Morris, C.12    Elledge, R.13    Buzdar, A.14
  • 95
    • 0037157603 scopus 로고    scopus 로고
    • Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomized trial
    • The ATAC Trialist Group Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomized trial. Lancet, 359: 2131-2139, 2002.
    • (2002) Lancet , vol.359 , pp. 2131-2139


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