Potentiation of natural killer cell activity with myricetin

Anticancer Research

Volumn 34, Issue 8, 2014, Pages 3975-3980

  Lindqvist, Christer ^a   Bobrowska Hägerstrand, Małgorzata ^a   Mrówczyńska, Lucyna ^b   Engblom, Christine ^a   Hägerstrand, Henry ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

^b ADAM MICKIEWICZ UNIVERSITY   (Poland)

Author keywords

Cytotoxicity; Myricetin; NK cells; Polyphenols; Quercetin

Indexed keywords

EUCHRESTAFLAVONE A; FLAVONOID; GENISTEIN; MYRICETIN; QUERCETIN; SOPHORAFLAVONE H; UNCLASSIFIED DRUG; POLYPHENOL;

ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG SCREENING; EFFECTOR CELL; ERYTHROLEUKEMIA CELL; HUMAN; HUMAN CELL; LYSIS; NATURAL KILLER CELL; CYTOTOXICITY; DOSE RESPONSE; DRUG EFFECT; IMMUNOLOGY; K562 CELL LINE; NK-CELLS;

CYTOTOXICITY; MYRICETIN; NK-CELLS; POLYPHENOLS; QUERCETIN;

DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; HUMANS; K562 CELLS; KILLER CELLS, NATURAL;

EID: 84908689742     PISSN: 02507005     EISSN: 17917530     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Lesschaeve I and Noble CA: Polyphenols: factors influencing their sensory properties and their effects on food and beverage preferences: Am J Clin Nutr 81: 330S-335S, 2005.
2. Romagnolo DF and Selmin OI: Flavonoids and cancer prevention: a review of the evidence. J Nutr Gerontol Geriatr 31: 206-238, 2012.
3. Dong JY and Qin LQ: Soy isoflavones consumption and risk of breast cancer incidence or recurrence: a meta-analysis of prospective studies. Breast Cancer Res Treat 125: 315-323, 2011.
4. Nöthlings U, Murphy SP, Wilkens LR, Henderson BE and Kolonel LN: Flavonols and Pancreatic Cancer Risk The Multiethnic Cohort Study. Am J Epidemiol 166: 924-931, 2007.
5. Burda S and Oleszek W: Antioxidant and antiradical activities of flavonoids. J Agric Food Chem 49: 2774-2779, 2001.
6. Kiessling R, Klein E and Wigzell H: "Natural" killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype. Eur J Immunol 5: 112-117, 1975.
7. Herbermann RB, Nunn ME and Lavrin DH: Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. I. Distribution of reactivity and specificity. Int J Cancer 16: 216-229, 1975.
8. Hercend T and Schmidt RE: Characteristics and uses of natural killer cells. Immunol Today 9: 291-293, 1988.
9. Long EO: Regulation of immune responses through inhibitory receptors. Annu Rev Immunol 17: 875-904, 1999.
10. Ljunggren HG and Kärre K: In search of the "missing self". MHC molecules and NK cell recognition. Immunol Today 11: 237-244, 1990.
11. Bauer S, Groh V, Wu J, Steinle A, Phillips JH, Lanier LL and Spies T: Activation of NK cells and T cells by NKG2, a receptor for stress-inducible MICA. Science 285: 727-729, 1999.
12. Moretta A, Biassoni R, Bottino C, Mingari MC and Moretta L: Natural cytotoxicity receptors that trigger human NK-mediated cytolysis. Immunol Today 21: 228-234, 2000.
13. Kirwan SE and Burshtyn DN: Regulation of natural killer cell activity. Curr Opin Immunol 19: 46-54, 2007.
14. Gong J-H, Maki G and Klingemann H-G: Characterization of a human cell line (NK-92) with phenotypocal and functional characteristics of activated natural killer cells. Leukemia 8: 652-658, 1994.
15. Lozzio CB and Lozzio B: Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood 45: 321-324, 1975.
16. Blomberg K, Hautala R, Lövgren J, Mukkala V-M, Lindqvist C and A˚kerman K: Time resolved fluorometric assay for natural killer activity using target cells labelled with a fluorescence enhancing ligand. J Immunol Meth 193: 199-206, 1996.
17. Orange JS: Formation and function of the lytic NK-cell immunological synapse. Nat Rev Immunol 8: 713-725, 2008.
18. Lanier LL: Up to the tightrope: natural killer cell activation and inhibition. Nat Immunol 9: 495-502, 2008.
19. Mrówczyńska L, Bobrowska-Hägerstrand M, Hägerstrand H and Lindqvist C: Increased sensitivity of cholera toxin B treated K562 cells to natural killer cells. Cell Immunol 269: 1-4, 2011.
20. Koch J, Steinle A, Watzl C and Mandelboim O: Activating natural cytotoxicity receptors of natural killer cells in cancer and infection. Trends Immunol 34: 182-191, 2013.
21. Tonn T, Becker S, Esser R, Schwabe D and Seifried E: Cellular immunotherapy of malignancies using the clonal natural killer cell line NK-92. J Hematother Stem Cell Res 10: 535-544, 2001.
22. Kang KA, Wang ZH, Zhang R, Piao MJ, Kim KC, Kang SS, Kim YW, Lee J, Park D and Hyun JW: Myricetin Protects Cells against Oxidative Stress-Induced Apoptosis via Regulation of PI3K/Akt and MAPK Signaling Pathways. Int J Mol Sci 11: 4348-4360, 2010.
23. Büchter C, Ackermann D, Havermann S, Honnen S, Chovolou Y, Fritz G, Kampkötter A and Wätjen W: Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16. Int J Mol Sci 14: 11895-11914, 2013.
24. Peraldi MN, Berrou J, Dulphy N, Seidowsky A, Haas P, Boissel N, Metivier F, Randoux C, Kossari N, Guérin A, Geffroy S, Delavaud G, Marin-Esteban V, Glotz D, Charron D and Toubert A: Oxidative stress mediates a reduced expression of the activating receptor NKG2D in NK cells from end-stage renal disease patients. J Immunol 182: 1696-1705, 2009.
25. Hui C, Qi X, Qianyong Z, Xiaoli P, Jundong Z and Mantian MJ: Flavonoids, flavonoid subclasses and breast cancer risk: a meta-analysis of epidemiologic studies. PLoS One 8: 1-8, 2013.