Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis

Immunology Today

Volumn 21, Issue 5, 2000, Pages 228-234

  Moretta, Alessandro ^a   Biassoni, Roberto ^b   Bottino, Cristina ^b   Mingari, Maria C ^a,b   Moretta, Lorenzo ^a,b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; CELL SURFACE RECEPTOR; CYTOKINE; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN; INTERLEUKIN 2; LIGAND; LYMPHOCYTE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MONOCLONAL ANTIBODY;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MOLECULAR CLONING; MOUSE; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TARGET CELL; VIRUS INFECTION;

EID: 0034117882     PISSN: 01675699     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5699(00)01596-6     Document Type: Note

References (41)

1. R.B. Herberman Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumours, I: distribution of reactivity and specificity Int. J. Cancer 16 1976 216 229
2. G. Trinchieri Biology of natural killer cells Adv. Immunol. 47 1989 187 376
3. H.G. Ljunggren K. Karre In search of the ‘missing self’: MHC molecules and NK cell recognition Immunol. Today 11 1990 237 244
4. L. Moretta Human NK cells: origin, clonality, specificity and receptors Adv. Immunol. 55 1994 341 380
5. A. Moretta Receptors for HLA-class I-molecules in human natural killer cells Annu. Rev. Immunol. 14 1996 619 648
6. L.L. Lanier NK cell receptors Annu. Rev. Immunol. 16 1998 359 393
7. E.O. Long Regulation of immune responses through inhibitory receptors Annu. Rev. Immunol. 17 1999 875 904
8. M. Colonna Specificity and function of immunoglobulin superfamily NK cell inhibitory and stimulatory receptors Immunol. Rev. 155 1997 127 133
9. N.M. Valiante Killer cell receptors: keeping pace with MHC class I evolution Immunol. Rev. 155 1997 155 164
10. A. Moretta Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes Immunol. Rev. 155 1997 105 117
11. M. Lopez-Botet Structure and function of the CD94 C-type lectin receptor complex involved in recognition of HLA class I molecules Immunol. Rev. 155 1997 165 174
12. M.C. Mingari Regulation of KIR expression in human T lymphocytes: a safety mechanism which may impair protective T cell responses Immunol. Today 19 1998 153 157
13. + cytotoxic T lymphocytes via CD2 50 kD sheep erythrocyte receptor J. Immunol. 136 1986 3939 3944
14. L.L. Lanier Functional and biochemical analysis of CD16 antigen on natural killer cells and granulocytes J. Immunol. 141 1988 3478 3485
15. A. Moretta CD69-mediated pathway of lymphocyte activation: anti-CD69 mAbs trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing TCR α/β J. Exp. Med. 174 1991 1393 1398
16. L.L. Lanier Arousal and inhibition of human NK cells Immunol. Rev. 155 1997 145 154
17. A. Moretta Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells J. Exp. Med. 182 1995 875 884
18. R. Biassoni The human leukocyte antigen (HLA)-C-specific ‘activatory’ or ‘inhibitory’ natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions J. Exp. Med. 183 1996 645 650
19. C. Cantoni The activating form of CD94 receptor complex: the CD94-associated Kp39 protein represents the product of the NKG2-C gene Eur. J. Immunol. 28 1998 327 338
20. L. Olcese Human killer cell activatory are included in a multimeric complex expressed by natural killer cells J. Immunol. 158 1997 5083 5086
21. L.L. Lanier Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells Nature 391 1998 703 707
22. L. Moretta Allorecognition by NK cells: nonself or no self? Immunol. Today 13 1992 300 306
23. S. Sivori NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh of cultured human NK cells: correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells Eur. J. Immunol. 29 1999 1647 1655
24. S. Sivori p46, a novel natural killer cell-specific surface molecule which mediates cell activation J. Exp. Med. 186 1997 1129 1136
25. M. Vitale NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells is involved in non-MHC restricted tumor cell lysis J. Exp. Med. 187 1998 2065 2072
26. D. Pende Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells J. Exp. Med. 190 1999 1505 1516
27. A. Pessino Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity J. Exp. Med. 188 1998 953 960
28. R. Biassoni The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity Eur. J. Immunol. 29 1999 1014 1020
29. C. Cantoni NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily J. Exp. Med. 189 1999 787 796
30. D. Cosman A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules Immunity 7 1997 273 282
31. J. Samaridis M. Colonna Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways Eur. J. Immunol. 27 1997 660 665
32. M. Falco Identification of the rat homologue of the human NKp46 triggering receptor Immunol. Lett. 68 1999 411 414
33. A. Moretta Novel surface molecules involved in human NK cell activation and triggering of the lytic machinery Int. J. Cancer 7 1992 6 10
34. P.A. Mathew Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells J. Immunol. 151 1993 5328 5337
35. N.M. Valiante G. Trinchieri Identification of a novel signal transduction surface molecule on human cytotoxic lymphocytes J. Exp. Med. 178 1993 1397 1406
36. H. Nakajima Activating interactions in human NK cell recognition: the role of 2B4–CD48 Eur. J. Immunol. 29 1999 1676 1683
37. S.G. Tangye Human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP J. Immunol. 162 1999 6981 6985
38. S. Sivori 2B4 functions as a co-receptor in human natural killer cell activation Eur. J. Immunol. 30 2000 787 793
39. S. Bauer Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA Science 285 1999 727 729
40. J. Wu An activating immunoreceptor complex formed by NKG2D and DAP-10 Science 285 1999 730 732
41. S.R. Nalabolu Genes in a 220-Kb region spanning the TNF cluster in human MHC Genomics 31 1996 215 222