Engrafted human stem cell-derived hepatocytes establish an infectious HCV murine model

Journal of Clinical Investigation

Volumn 124, Issue 11, 2014, Pages 4953-4964

  Carpentier, Arnaud ^a   Tesfaye, Abeba ^a,b   Chu, Virginia ^a   Nimgaonkar, Ila ^a   Zhang, Fang ^a   Lee, Seung Bum ^c   Thorgeirsson, Snorri S ^c   Feinstone, Stephen M ^a,b   Liang, T Jake ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD81 ANTIGEN; CYTOCHROME P450 3A4; UROKINASE; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CONTACT; CELL DIFFERENTIATION; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDODERM; HEPATITIS C; HEPATOCYTE TRANSPLANTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPID STORAGE; LIPOPROTEIN SECRETION; LIVER CELL; LIVER DEVELOPMENT; LIVER PARENCHYMA; MOUSE; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PROTEIN URINE LEVEL; STEM CELL DERIVED HEPATOCYTE TRANSPLANTATION; VIRUS REPLICATION; ANIMAL; CELL CULTURE; DISEASE MODEL; EMBRYONIC STEM CELL; HEPACIVIRUS; LIVER; METABOLISM; PATHOLOGY; PHYSIOLOGY; SCID MOUSE; TRANSPLANTATION; VIROLOGY;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; HEPACIVIRUS; HEPATITIS C; HEPATOCYTES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LIVER; MICE; MICE, SCID; VIRAL PROTEINS;

EID: 84908627887     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI75456     Document Type: Article

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