Direct reprogramming of human fibroblasts to functional and expandable hepatocytes

Cell Stem Cell

Volumn 14, Issue 3, 2014, Pages 370-384

  Huang, Pengyu ^a   Zhang, Ludi ^a   Gao, Yimeng ^a   He, Zhiying ^b   Yao, Dan ^c   Wu, Zhitao ^c   Cen, Jin ^a   Chen, Xiaotao ^a   Liu, Changcheng ^b   Hu, Yiping ^b   Lai, Dongmei ^d   Hu, Zhenlei ^e   Chen, Li ^f   Zhang, Ying ^f   Cheng, Xin ^a   Ma, Xiaojun ^f   Pan, Guoyu ^c   Wang, Xin ^g,h,i   Hui, Lijian ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^d Shanghai Municipal Key Clinical Specialty Shanghai Jiao Tong University School of Medicine   (China)

^e SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^f DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^g INNER MONGOLIA UNIVERSITY   (China)

^h UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

ⁱ Hepatoscience Incorporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLCHOLANTHRENE; CELL NUCLEUS RECEPTOR; CONCANAVALIN A; COUMARIN; CYTOCHROME P450; DEXTROMETHORPHAN; ENZYME; FUMARYLACETOACETATE DEHYDROLASE; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 3GAMMA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; PHENACETIN; PHENOBARBITAL; RIFAMPICIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; FUMARYLACETOACETASE; LENTIVIRUS VECTOR; VIRUS LARGE T ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILIARY EXCRETION; CELL LINEAGE; DETOXIFICATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; FIBROBLAST; GENE EXPRESSION; HEPATOCYTE TRANSPLANTATION; HUMAN; HUMAN CELL; LENTIVIRINAE; LIQUID CHROMATOGRAPHY; LIVER CELL; LIVER DISEASE; LIVER FAILURE; METABOLIC DISORDER; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; ACUTE LIVER FAILURE; ADULT; ANIMAL TISSUE; CELL EXPANSION; CELL FUNCTION; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; FETUS; FULMINANT HEPATIC FAILURE; HEPATIC PROGENITOR CELL; IN VITRO STUDY; LIVER FUNCTION; METABOLIC LIVER DISEASE; NUCLEOTIDE SEQUENCE;

MUS;

ADULT; ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BILIARY TRACT; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CONCANAVALIN A; FETUS; FIBROBLASTS; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; HYDROLASES; LIVER FAILURE; METABOLIC DETOXICATION, DRUG; MICE; MICE, INBRED C57BL; NUCLEAR REPROGRAMMING; STEM CELLS;

EID: 84896142695     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2014.01.003     Document Type: Article

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