Iron chelation acutely stimulates fetal human intestinal cell production of IL-6 and VEGF while decreasing HGF: The roles of p38, ERK, and JNK MAPK signaling

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 292, Issue 4, 2007, Pages

  Markel, Troy A ^a   Crisostomo, Paul R ^a   Wang, Meijing ^a   Herring, Christine M ^a   Lahm, Tim ^a   Meldrum, Kirstan K ^a   Lillemoe, Keith D ^a   Rescorla, Frederick J ^a   Meldrum, Daniel R ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b Emerson Hall 215 ^*  (United States)

Author keywords

c Jun NH2 terminal kinase; Extracellular signal regulated kinase; Hepatocyte growth factor; Inflammation; Interleukin 6; Intestinal ischemia; Mitogen activated protein kinase signaling; Vascular endothelial growth factor

Indexed keywords

DEFEROXAMINE; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SCATTER FACTOR; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FETUS CELL; HUMAN; HUMAN CELL; INTESTINE CELL; IRON CHELATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE; DEFEROXAMINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FETUS; HUMANS; INTERLEUKIN-6; INTESTINAL MUCOSA; IRON CHELATING AGENTS; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 34147153241     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00502.2006     Document Type: Article

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