TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7

Vaccine

Volumn 32, Issue 43, 2014, Pages 5593-5599

  Lai, Chao Yang ^a   Liu, Yi Ling ^a   Yu, Guann Yi ^a   Maa, Ming Chei ^b   Leu, Tzeng Horng ^c   Xu, Congfeng ^d   Luo, Yunping ^e   Xiang, Rong ^f   Chuang, Tsung Hsien ^a,g  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^f NANKAI UNIVERSITY   (China)

^g KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Adjuvant activity; Innate immunity; Pattern recognition receptor; Species specific recognition; Toll like receptor

Indexed keywords

ALUMINUM SALT; CL 075; CL 097; CL 264; COMPLEMENTARY DNA; FREUND ADJUVANT; GAMMA INTERFERON; GARDIQUIMOD; IMIDAZOQUINOLINE DERIVATIVE; IMIQUIMOD; IMMUNOGLOBULIN M; INTERLEUKIN 6; INTERLEUKIN 8; LOXORIBINE; RESIQUIMOD; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 7 AGONIST; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 8 AGONIST; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG; CYTOKINE; LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOREACTIVITY; IMMUNOREGULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; RABBIT; SEQUENCE ANALYSIS; SPLEEN CELL; AGONISTS; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY PRODUCTION; CELL CULTURE; CYTOLOGY; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SPLEEN;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODY FORMATION; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; HEK293 CELLS; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RABBITS; SPLEEN; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

EID: 84908514137     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.07.104     Document Type: Article

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