-
1
-
-
59149085501
-
The global burden of hepatitis C
-
Lavanchy D. The global burden of hepatitis C. Liver Int. 2009;29 Suppl 1:74-81.
-
(2009)
Liver Int.
, vol.29
, pp. 74-81
-
-
Lavanchy, D.1
-
2
-
-
0036142230
-
Iron as a comorbid factor in chronic viral hepatitis
-
Bonkovsky HL. Iron as a comorbid factor in chronic viral hepatitis. Am J Gastroenterol. 2002;97(1):1-4.
-
(2002)
Am J Gastroenterol.
, vol.97
, Issue.1
, pp. 1-4
-
-
Bonkovsky, H.L.1
-
3
-
-
34948817771
-
Hepatic iron accumulation is associated with disease progression and resistance to interferon/ribavirin combination therapy in chronic hepatitis C
-
Fujita N, Sugimoto R, Urawa N, Araki J, Mifuji R, Yamamoto M, et al. Hepatic iron accumulation is associated with disease progression and resistance to interferon/ribavirin combination therapy in chronic hepatitis C. J Gastroenterol Hepatol. 2007;22(11):1886- 93.
-
(2007)
J Gastroenterol Hepatol.
, vol.22
, Issue.11
, pp. 1886-1893
-
-
Fujita, N.1
Sugimoto, R.2
Urawa, N.3
Araki, J.4
Mifuji, R.5
Yamamoto, M.6
-
4
-
-
1442350427
-
Clinical significance of hepatic iron deposition and serum iron values in patients with chronic hepatitis C infection
-
Metwally MA, Zein CO, Zein NN. Clinical significance of hepatic iron deposition and serum iron values in patients with chronic hepatitis C infection. Am J Gastroenterol. 2004;99(2):286-91.
-
(2004)
Am J Gastroenterol.
, vol.99
, Issue.2
, pp. 286-291
-
-
Metwally, M.A.1
Zein, C.O.2
Zein, N.N.3
-
5
-
-
77649266238
-
The role of iron overload and HFE gene mutations in the era of pegylated interferon and ribavirin treatment of chronic hepatitis C
-
Sikorska K, Stalke P, Izycka-Swieszewska E, Romanowski T, Bielawski KP. The role of iron overload and HFE gene mutations in the era of pegylated interferon and ribavirin treatment of chronic hepatitis C. Med Sci Monit. 2010;16(3):CR137-43.
-
(2010)
Med Sci Monit.
, vol.16
, Issue.3
, pp. CR137-CR143
-
-
Sikorska, K.1
Stalke, P.2
Izycka-Swieszewska, E.3
Romanowski, T.4
Bielawski, K.P.5
-
6
-
-
31044433625
-
Hepatocellular carcinoma caused by iron overload: A possible mechanism of direct hepatocarcinogenicity
-
Asare GA, Mossanda KS, Kew MC, Paterson AC, Kahler-Venter CP, Siziba K. Hepatocellular carcinoma caused by iron overload: a possible mechanism of direct hepatocarcinogenicity. Toxicology. 2006;219(1-3):41-52.
-
(2006)
Toxicology.
, vol.219
, Issue.1-3
, pp. 41-52
-
-
Asare, G.A.1
Mossanda, K.S.2
Kew, M.C.3
Paterson, A.C.4
Kahler-Venter, C.P.5
Siziba, K.6
-
7
-
-
70350567326
-
Hepatic iron overload and hepatocellular carcinoma
-
Kew MC. Hepatic iron overload and hepatocellular carcinoma. Cancer Lett. 2009;286(1):38-43.
-
(2009)
Cancer Lett.
, vol.286
, Issue.1
, pp. 38-43
-
-
Kew, M.C.1
-
8
-
-
78651455570
-
Beyond hereditary hemochromatosis: New insights into the relationship between iron overload and chronic liver diseases
-
Fargion S, Valenti L, Fracanzani AL. Beyond hereditary hemochromatosis: new insights into the relationship between iron overload and chronic liver diseases. Dig Liver Dis. 2011;43(2):89-95.
-
(2011)
Dig Liver Dis.
, vol.43
, Issue.2
, pp. 89-95
-
-
Fargion, S.1
Valenti, L.2
Fracanzani, A.L.3
-
9
-
-
56149115918
-
Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity
-
Miura K, Taura K, Kodama Y, Schnabl B, Brenner DA. Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity. Hepatology. 2008;48(5):1420-9.
-
(2008)
Hepatology.
, vol.48
, Issue.5
, pp. 1420-1429
-
-
Miura, K.1
Taura, K.2
Kodama, Y.3
Schnabl, B.4
Brenner, D.A.5
-
10
-
-
37349065804
-
Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription
-
Nishina S, Hino K, Korenaga M, Vecchi C, Pietrangelo A, Mizukami Y, et al. Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription. Gastroenterology. 2008;134(1):226-38.
-
(2008)
Gastroenterology.
, vol.134
, Issue.1
, pp. 226-238
-
-
Nishina, S.1
Hino, K.2
Korenaga, M.3
Vecchi, C.4
Pietrangelo, A.5
Mizukami, Y.6
-
11
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci U S A. 2001;98(15):8780-5.
-
(2001)
Proc Natl Acad Sci U S A.
, vol.98
, Issue.15
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
Beaumont, C.4
Grandchamp, B.5
Kahn, A.6
-
12
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306(5704):2090-3.
-
(2004)
Science.
, vol.306
, Issue.5704
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
Vaughn, M.B.4
Donovan, A.5
Ward, D.M.6
-
13
-
-
84885768132
-
Systemic iron homeostasis
-
Ganz T. Systemic iron homeostasis. Physiol Rev. 2013;93(4):1721-41.
-
(2013)
Physiol Rev.
, vol.93
, Issue.4
, pp. 1721-1741
-
-
Ganz, T.1
-
14
-
-
33846212344
-
STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo
-
Pietrangelo A, Dierssen U, Valli L, Garuti C, Rump A, Corradini E, et al. STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo. Gastroenterology. 2007;132(1):294-300.
-
(2007)
Gastroenterology.
, vol.132
, Issue.1
, pp. 294-300
-
-
Pietrangelo, A.1
Dierssen, U.2
Valli, L.3
Garuti, C.4
Rump, A.5
Corradini, E.6
-
15
-
-
63449103712
-
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
-
Andriopoulos B, Jr., Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, et al. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet. 2009;41(4):482-7.
-
(2009)
Nat Genet.
, vol.41
, Issue.4
, pp. 482-487
-
-
Andriopoulos, B.1
Corradini, E.2
Xia, Y.3
Faasse, S.A.4
Chen, S.5
Grgurevic, L.6
-
16
-
-
78649634981
-
Hepcidin in human iron disorders: Therapeutic implications
-
Pietrangelo A. Hepcidin in human iron disorders: therapeutic implications. J Hepatol. 2011;54(1):173-81.
-
(2011)
J Hepatol.
, vol.54
, Issue.1
, pp. 173-181
-
-
Pietrangelo, A.1
-
17
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem. 2001;276(11):7806-10.
-
(2001)
J Biol Chem.
, vol.276
, Issue.11
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
Ganz, T.4
-
18
-
-
15744383449
-
Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus
-
Fillebeen C, Rivas-Estilla AM, Bisaillon M, Ponka P, Muckenthaler M, Hentze MW, et al. Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus. J Biol Chem. 2005;280(10):9049-57.
-
(2005)
J Biol Chem.
, vol.280
, Issue.10
, pp. 9049-9057
-
-
Fillebeen, C.1
Rivas-Estilla, A.M.2
Bisaillon, M.3
Ponka, P.4
Muckenthaler, M.5
Hentze, M.W.6
-
19
-
-
78049455727
-
Iron inhibits replication of infectious hepatitis C virus in permissive Huh7.5.1 cells
-
Fillebeen C, Pantopoulos K. Iron inhibits replication of infectious hepatitis C virus in permissive Huh7.5.1 cells. J Hepatol. 2010;53(6):995-9.
-
(2010)
J Hepatol.
, vol.53
, Issue.6
, pp. 995-999
-
-
Fillebeen, C.1
Pantopoulos, K.2
-
20
-
-
3943098598
-
Iron regulates hepatitis C virus translation via stimulation of expression of translation initiation factor 3
-
Theurl I, Zoller H, Obrist P, Datz C, Bachmann F, Elliott RM, et al. Iron regulates hepatitis C virus translation via stimulation of expression of translation initiation factor 3. J Infect Dis. 2004;190(4):819-25.
-
(2004)
J Infect Dis.
, vol.190
, Issue.4
, pp. 819-825
-
-
Theurl, I.1
Zoller, H.2
Obrist, P.3
Datz, C.4
Bachmann, F.5
Elliott, R.M.6
-
21
-
-
49849091690
-
Iron increases translation initiation directed by internal ribosome entry site of hepatitis C virus
-
Cho H, Lee HC, Jang SK, Kim YK. Iron increases translation initiation directed by internal ribosome entry site of hepatitis C virus. Virus Genes. 2008;37(2):154-60.
-
(2008)
Virus Genes.
, vol.37
, Issue.2
, pp. 154-160
-
-
Cho, H.1
Lee, H.C.2
Jang, S.K.3
Kim, Y.K.4
-
22
-
-
80051739560
-
Modulation of hepatitis C virus replication by iron and hepcidin in Huh7 hepatocytes
-
Bartolomei G, Cevik RE, Marcello A. Modulation of hepatitis C virus replication by iron and hepcidin in Huh7 hepatocytes. J Gen Virol. 2011;92(Pt 9):2072-81.
-
(2011)
J Gen Virol.
, vol.92
, pp. 2072-2081
-
-
Bartolomei, G.1
Cevik, R.E.2
Marcello, A.3
-
23
-
-
84867692347
-
Iron regulator hepcidin exhibits antiviral activity against hepatitis C virus
-
Liu H, Trinh TL, Dong H, Keith R, Nelson D, Liu C. Iron regulator hepcidin exhibits antiviral activity against hepatitis C virus. PLoS One. 2012;7(10).
-
(2012)
PLoS One.
, vol.7
, Issue.10
-
-
Liu, H.1
Trinh, T.L.2
Dong, H.3
Keith, R.4
Nelson, D.5
Liu, C.6
-
24
-
-
79960453276
-
EASL Clinical Practice Guidelines: Management of hepatitis C virus infection
-
European Association for the Study of the L. EASL Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol. 2011;55(2):245-64.
-
(2011)
J Hepatol.
, vol.55
, Issue.2
, pp. 245-264
-
-
-
25
-
-
48349098530
-
GUS and PMM1 as suitable reference genes for gene expression analysis in the liver tissue of patients with chronic hepatitis
-
Romanowski T, Sikorska K, Bielawski KP. GUS and PMM1 as suitable reference genes for gene expression analysis in the liver tissue of patients with chronic hepatitis. Med Sci Monit. 2008;14(7):BR147-52.
-
(2008)
Med Sci Monit.
, vol.14
, Issue.7
, pp. BR147-BR152
-
-
Romanowski, T.1
Sikorska, K.2
Bielawski, K.P.3
-
26
-
-
0037129827
-
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
-
RESEARCH0034
-
Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002;3(7):RESEARCH0034.
-
(2002)
Genome Biol.
, vol.3
, Issue.7
-
-
Vandesompele, J.1
De Preter, K.2
Pattyn, F.3
Poppe, B.4
Van Roy, N.5
De Paepe, A.6
-
27
-
-
33947103479
-
Liver iron is a surrogate marker of severe fibrosis in chronic hepatitis C
-
Guyader D, Thirouard AS, Erdtmann L, Rakba N, Jacquelinet S, Danielou H, et al. Liver iron is a surrogate marker of severe fibrosis in chronic hepatitis C. J Hepatol. 2007;46(4):587-95.
-
(2007)
J Hepatol.
, vol.46
, Issue.4
, pp. 587-595
-
-
Guyader, D.1
Thirouard, A.S.2
Erdtmann, L.3
Rakba, N.4
Jacquelinet, S.5
Danielou, H.6
-
28
-
-
53249142510
-
Patients with chronic hepatitis C achieving a sustained virological response to peginterferon and ribavirin therapy recover from impaired hepcidin secretion
-
Fujita N, Sugimoto R, Motonishi S, Tomosugi N, Tanaka H, Takeo M, et al. Patients with chronic hepatitis C achieving a sustained virological response to peginterferon and ribavirin therapy recover from impaired hepcidin secretion. J Hepatol. 2008;49(5):702-10.
-
(2008)
J Hepatol.
, vol.49
, Issue.5
, pp. 702-710
-
-
Fujita, N.1
Sugimoto, R.2
Motonishi, S.3
Tomosugi, N.4
Tanaka, H.5
Takeo, M.6
-
29
-
-
11144280608
-
Liver hepcidin mRNA correlates with iron stores, but not inflammation, in patients with chronic hepatitis C
-
Aoki CA, Rossaro L, Ramsamooj R, Brandhagen D, Burritt MF, Bowlus CL. Liver hepcidin mRNA correlates with iron stores, but not inflammation, in patients with chronic hepatitis C. J Clin Gastroenterol. 2005;39(1):71-4.
-
(2005)
J Clin Gastroenterol.
, vol.39
, Issue.1
, pp. 71-74
-
-
Aoki, C.A.1
Rossaro, L.2
Ramsamooj, R.3
Brandhagen, D.4
Burritt, M.F.5
Bowlus, C.L.6
-
30
-
-
84877007665
-
Hepcidin mRNA level as a parameter of disease progression in chronic hepatitis C and hepatocellular carcinoma
-
Abd Elmonem E, Tharwa el S, Farag MA, Fawzy A, El Shinnawy SF, Suliman S. Hepcidin mRNA level as a parameter of disease progression in chronic hepatitis C and hepatocellular carcinoma. J Egypt Natl Canc Inst. 2009;21(4):333-42.
-
(2009)
J Egypt Natl Canc Inst.
, vol.21
, Issue.4
, pp. 333-342
-
-
Abd Elmonem, E.1
el Tharwa, S.2
Farag, M.A.3
Fawzy, A.4
El Shinnawy, S.F.5
Suliman, S.6
-
31
-
-
70349746734
-
Reduced serum hepcidin levels in patients with chronic hepatitis C
-
Girelli D, Pasino M, Goodnough JB, Nemeth E, Guido M, Castagna A, et al. Reduced serum hepcidin levels in patients with chronic hepatitis C. J Hepatol. 2009;51(5):845-52.
-
(2009)
J Hepatol.
, vol.51
, Issue.5
, pp. 845-852
-
-
Girelli, D.1
Pasino, M.2
Goodnough, J.B.3
Nemeth, E.4
Guido, M.5
Castagna, A.6
-
32
-
-
56649099169
-
Altered expression of iron regulatory genes in cirrhotic human livers: Clues to the cause of hemosiderosis?
-
Bergmann OM, Mathahs MM, Broadhurst KA, Weydert JA, Wilkinson N, Howe JR, et al. Altered expression of iron regulatory genes in cirrhotic human livers: clues to the cause of hemosiderosis? Lab Invest. 2008;88(12):1349-57.
-
(2008)
Lab Invest.
, vol.88
, Issue.12
, pp. 1349-1357
-
-
Bergmann, O.M.1
Mathahs, M.M.2
Broadhurst, K.A.3
Weydert, J.A.4
Wilkinson, N.5
Howe, J.R.6
-
33
-
-
79959562083
-
Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice
-
Corradini E, Meynard D, Wu Q, Chen S, Ventura P, Pietrangelo A, et al. Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice. Hepatology. 2011;54(1):273-84.
-
(2011)
Hepatology.
, vol.54
, Issue.1
, pp. 273-284
-
-
Corradini, E.1
Meynard, D.2
Wu, Q.3
Chen, S.4
Ventura, P.5
Pietrangelo, A.6
-
34
-
-
84908533396
-
-
editors. Fourth Congress of the International BioIron Society (IBIS), Biennal World Meeting (BioIron 2013).; Vancouver, Canada
-
Eddowes LA, Ramamurthy N, Ryan J, Boninsegna S, Armitage A, Fabris P, editors. Hepatitis C virus disrupts BMP/SMAD signaling suppressing hepcidin.; Fourth Congress of the International BioIron Society (IBIS), Biennal World Meeting (BioIron 2013).; 2012; Vancouver, Canada. p. 68.
-
(2012)
Hepatitis C virus disrupts BMP/SMAD signaling suppressing hepcidin.
-
-
Eddowes, L.A.1
Ramamurthy, N.2
Ryan, J.3
Boninsegna, S.4
Armitage, A.5
Fabris, P.6
-
35
-
-
84880616927
-
Distribution of HCV genotypes in Poland
-
Panasiuk A, Flisiak R, Mozer-Lisewska I, Adamek A, Tyczyno M, Halota W, et al. Distribution of HCV genotypes in Poland. Przegl Epidemiol. 2013;67(1):11-6.
-
(2013)
Przegl Epidemiol.
, vol.67
, Issue.1
, pp. 11-16
-
-
Panasiuk, A.1
Flisiak, R.2
Mozer-Lisewska, I.3
Adamek, A.4
Tyczyno, M.5
Halota, W.6
-
36
-
-
61849160363
-
A functional genomic screen identifies cellular cofactors of hepatitis C virus replication
-
Tai AW, Benita Y, Peng LF, Kim SS, Sakamoto N, Xavier RJ, et al. A functional genomic screen identifies cellular cofactors of hepatitis C virus replication. Cell Host Microbe. 2009;5(3):298-307.
-
(2009)
Cell Host Microbe.
, vol.5
, Issue.3
, pp. 298-307
-
-
Tai, A.W.1
Benita, Y.2
Peng, L.F.3
Kim, S.S.4
Sakamoto, N.5
Xavier, R.J.6
-
37
-
-
84864332902
-
Pegylated interferon-alpha induced hypoferremia is associated with the immediate response to treatment in hepatitis C
-
Ryan JD, Altamura S, Devitt E, Mullins S, Lawless MW, Muckenthaler MU, et al. Pegylated interferon-alpha induced hypoferremia is associated with the immediate response to treatment in hepatitis C. Hepatology. 2012;56(2):492-500.
-
(2012)
Hepatology.
, vol.56
, Issue.2
, pp. 492-500
-
-
Ryan, J.D.1
Altamura, S.2
Devitt, E.3
Mullins, S.4
Lawless, M.W.5
Muckenthaler, M.U.6
-
38
-
-
84896493619
-
Hepcidin as a predictor of treatment response in chronic hepatitis C infection
-
Strnad P, Nuraldeen R, Fischer J, Berg T, Trautwein C. Hepcidin as a predictor of treatment response in chronic hepatitis C infection. Hepatology. 2014;59(4):1648.
-
(2014)
Hepatology.
, vol.59
, Issue.4
, pp. 1648
-
-
Strnad, P.1
Nuraldeen, R.2
Fischer, J.3
Berg, T.4
Trautwein, C.5
|