Indoxyl sulfate-induced activation of (pro)renin receptor promotes cell proliferation and tissue factor expression in vascular smooth muscle cells

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Yisireyili, Maimaiti ^a   Saito, Shinichi ^a   Abudureyimu, Shaniya ^a   Adelibieke, Yelixiati ^a   Ng, Hwee Yeong ^c   Nishijima, Fuyuhiko ^b   Takeshita, Kyosuke ^a   Murohara, Toyoaki ^a   Niwa, Toshimitsu ^a,d  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KUREHA CORPORATION   (Japan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d SHUBUN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; AROMATIC HYDROCARBON RECEPTOR; DIPHENYLIODONIUM SALT; INDICAN; ORGANIC ANION TRANSPORTER 3; PRORENIN; PRORENIN RECEPTOR; REACTIVE OXYGEN METABOLITE; RENIN; SMALL INTERFERING RNA; THROMBOPLASTIN; TRANSCRIPTION FACTOR RELA; ATP6AP2 PROTEIN, HUMAN; CATION; CELL SURFACE RECEPTOR; ORGANIC ANION TRANSPORTER; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CELL PROLIFERATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPERTENSION; NONHUMAN; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; BIOSYNTHESIS; CHRONIC KIDNEY FAILURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY;

ANIMALS; AORTA; CELL PROLIFERATION; GENE EXPRESSION REGULATION; HUMANS; INDICAN; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; ONIUM COMPOUNDS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; RATS; RECEPTORS, CELL SURFACE; RENAL INSUFFICIENCY, CHRONIC; RNA, SMALL INTERFERING; THROMBOPLASTIN; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84908460048     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109268     Document Type: Article

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