Indoxyl sulfate promotes cardiac fibrosis with enhanced oxidative stress in hypertensive rats

Life Sciences

Volumn 92, Issue 24-26, 2013, Pages 1180-1185

  Yisireyili, Maimaiti ^a   Shimizu, Hidehisa ^a   Saito, Shinichi ^a   Enomoto, Atsushi ^a   Nishijima, Fuyuhiko ^b   Niwa, Toshimitsu ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KUREHA CORPORATION   (Japan)

Author keywords

Fibrosis; Heart; Indoxyl sulfate; Nrf2; Oxidative stress; Uremic toxin

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; HEME OXYGENASE 1; INDICAN; MALONALDEHYDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; DRUG INDUCED DISEASE; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART VENTRICLE; HEART WEIGHT; IMMUNOHISTOCHEMISTRY; NONHUMAN; OXIDATIVE STRESS; RANDOMIZED CONTROLLED TRIAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; CARDIOMEGALY; FIBROSIS; HYPERTENSION; INDICAN; OXIDATIVE STRESS; RANDOM ALLOCATION; RATS; RATS, INBRED DAHL;

RATTUS;

EID: 84879420399     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.05.008     Document Type: Article

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