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Volumn 22, Issue 1, 2012, Pages 176-180

AST-120 Ameliorates Epithelial-to-Mesenchymal Transition and Interstitial Fibrosis in the Kidneys of Chronic Kidney Disease Rats

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; AST 120; CARBON; INDICAN; MEMBRANE PROTEIN; OXIDE; PHOSPHOPROTEIN; PROTEIN ZO1; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84855175734     PISSN: 10512276     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.jrn.2011.10.015     Document Type: Article
Times cited : (41)

References (30)
  • 1
    • 0028466186 scopus 로고
    • Indoxyl sulfate, a circulating uremic toxin, stimulates the progression of glomerular sclerosis
    • Niwa T., Ise M. Indoxyl sulfate, a circulating uremic toxin, stimulates the progression of glomerular sclerosis. J Lab Clin Med 1994, 124:96-104.
    • (1994) J Lab Clin Med , vol.124 , pp. 96-104
    • Niwa, T.1    Ise, M.2
  • 2
    • 33744809267 scopus 로고    scopus 로고
    • Indoxyl sulfate induces complex redox alterations in mesangial cells
    • Gelasco A.K., Raymond J.R. Indoxyl sulfate induces complex redox alterations in mesangial cells. Am J Physiol Renal Physiol 2006, 290:F1551-F1558.
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Gelasco, A.K.1    Raymond, J.R.2
  • 3
    • 34250163587 scopus 로고    scopus 로고
    • The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells
    • Dou L., Jourde-Chiche N., Faure V., et al. The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells. JThromb Haemost 2007, 5:1302-1308.
    • (2007) JThromb Haemost , vol.5 , pp. 1302-1308
    • Dou, L.1    Jourde-Chiche, N.2    Faure, V.3
  • 4
    • 58149146910 scopus 로고    scopus 로고
    • Indoxyl sulfate inhibits nitric oxide production and cell viability by inducing oxidative stress in vascular endothelial cells
    • Tumur Z., Niwa T. Indoxyl sulfate inhibits nitric oxide production and cell viability by inducing oxidative stress in vascular endothelial cells. Am J Nephrol 2009, 29:551-557.
    • (2009) Am J Nephrol , vol.29 , pp. 551-557
    • Tumur, Z.1    Niwa, T.2
  • 5
    • 67651100885 scopus 로고    scopus 로고
    • Indoxyl sulphate induces oxidative stress and the expression of osteoblasts-specific proteins in vascular smooth muscle cells
    • Muteliefu G., Enomoto A., Jiang P., Takahashi M., Niwa T. Indoxyl sulphate induces oxidative stress and the expression of osteoblasts-specific proteins in vascular smooth muscle cells. Nephrol Dial Transplant 2009, 24:2051-2058.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2051-2058
    • Muteliefu, G.1    Enomoto, A.2    Jiang, P.3    Takahashi, M.4    Niwa, T.5
  • 6
    • 58049157534 scopus 로고    scopus 로고
    • Indoxyl sulfate promotes proliferation of human aortic smooth muscle cells by inducing oxidative stress
    • Muteliefu G., Enomoto A., Niwa T. Indoxyl sulfate promotes proliferation of human aortic smooth muscle cells by inducing oxidative stress. J Ren Nutr 2009, 19:29-32.
    • (2009) J Ren Nutr , vol.19 , pp. 29-32
    • Muteliefu, G.1    Enomoto, A.2    Niwa, T.3
  • 7
    • 68849102859 scopus 로고    scopus 로고
    • ROS and PDGF-β receptors are critically involved in indoxyl sulfate actions that promote vascular smooth muscle cell proliferation and migration
    • Shimizu H., Hirose Y., Nishijima F., Tsubakihara Y., Miyazaki H. ROS and PDGF-β receptors are critically involved in indoxyl sulfate actions that promote vascular smooth muscle cell proliferation and migration. Am J Physiol Cell Physiol 2009, 297:C389-C396.
    • (2009) Am J Physiol Cell Physiol , vol.297
    • Shimizu, H.1    Hirose, Y.2    Nishijima, F.3    Tsubakihara, Y.4    Miyazaki, H.5
  • 8
    • 44449148845 scopus 로고    scopus 로고
    • Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats
    • Adijiang A., Goto S., Uramoto S., Nishijima F., Niwa T. Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats. Nephrol Dial Transplant 2008, 23:1892-1901.
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 1892-1901
    • Adijiang, A.1    Goto, S.2    Uramoto, S.3    Nishijima, F.4    Niwa, T.5
  • 9
    • 77956266118 scopus 로고    scopus 로고
    • Indoxyl sulfate, a uremic toxin, promotes cell senescence in aorta of hypertensive rats
    • Adijiang A., Higuchi Y., Nishijima F., Shimizu H., Niwa T. Indoxyl sulfate, a uremic toxin, promotes cell senescence in aorta of hypertensive rats. Biochem Biophys Res Commun 2010, 399:637-641.
    • (2010) Biochem Biophys Res Commun , vol.399 , pp. 637-641
    • Adijiang, A.1    Higuchi, Y.2    Nishijima, F.3    Shimizu, H.4    Niwa, T.5
  • 10
    • 84943010134 scopus 로고    scopus 로고
    • Indoxyl sulfate is a nephro-vascular toxin
    • Niwa T. Indoxyl sulfate is a nephro-vascular toxin. J Ren Nutr 2010, 20(suppl 5):S2-S6.
    • (2010) J Ren Nutr , vol.20 , Issue.SUPPL. 5
    • Niwa, T.1
  • 11
    • 0030686486 scopus 로고    scopus 로고
    • Indoxyl sulfate and progression of renal failure: effects of low-protein diet and oral sorbent on indoxyl sulfate production in uremic rats and undialyzed uremic patients
    • Niwa T., Tsukushi S., Ise M., et al. Indoxyl sulfate and progression of renal failure: effects of low-protein diet and oral sorbent on indoxyl sulfate production in uremic rats and undialyzed uremic patients. Miner Electrolyte Metab 1997, 23:179-184.
    • (1997) Miner Electrolyte Metab , vol.23 , pp. 179-184
    • Niwa, T.1    Tsukushi, S.2    Ise, M.3
  • 12
    • 0030663544 scopus 로고    scopus 로고
    • The protein metabolite hypothesis, a model for the progression renal failure: an oral sorbent lowers indoxyl sulfate levels in undialyzed uremic patients
    • Niwa T., Nomura T., Sugiyama S., Miyazaki T., Tsukushi S., Tsutsui S. The protein metabolite hypothesis, a model for the progression renal failure: an oral sorbent lowers indoxyl sulfate levels in undialyzed uremic patients. Kidney Int 1997, 52(suppl 62):S23-S28.
    • (1997) Kidney Int , vol.52 , Issue.SUPPL. 62
    • Niwa, T.1    Nomura, T.2    Sugiyama, S.3    Miyazaki, T.4    Tsukushi, S.5    Tsutsui, S.6
  • 13
    • 0033762864 scopus 로고    scopus 로고
    • An oral sorbent reduces overload of indoxyl sulfate and gene expression of TGF-β1 in uremic rat kidneys
    • Miyazaki T., Aoyama I., Ise M., Seo H., Niwa T. An oral sorbent reduces overload of indoxyl sulfate and gene expression of TGF-β1 in uremic rat kidneys. Nephrol Dial Transplant 2000, 15:1773-1781.
    • (2000) Nephrol Dial Transplant , vol.15 , pp. 1773-1781
    • Miyazaki, T.1    Aoyama, I.2    Ise, M.3    Seo, H.4    Niwa, T.5
  • 14
    • 0036187485 scopus 로고    scopus 로고
    • Combination therapy with benazepril and oral adsorbent ameliorates progressive renal fibrosis in uremic rats
    • Aoyama I., Shimokata K., Niwa T. Combination therapy with benazepril and oral adsorbent ameliorates progressive renal fibrosis in uremic rats. Nephron 2002, 90:297-312.
    • (2002) Nephron , vol.90 , pp. 297-312
    • Aoyama, I.1    Shimokata, K.2    Niwa, T.3
  • 15
    • 33845733638 scopus 로고    scopus 로고
    • Indoxyl sulfate-lowering capacity of oral sorbents affects prognosis of kidney function and oxidative stress in chronic kidney disease
    • Taki K., Niwa T. Indoxyl sulfate-lowering capacity of oral sorbents affects prognosis of kidney function and oxidative stress in chronic kidney disease. J Ren Nutr 2007, 17:48-52.
    • (2007) J Ren Nutr , vol.17 , pp. 48-52
    • Taki, K.1    Niwa, T.2
  • 17
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • Kalluri R., Neilson E.G. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003, 112:1776-1784.
    • (2003) J Clin Invest , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 18
    • 0035661067 scopus 로고    scopus 로고
    • Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)
    • Oldfield M.D., Bach L.A., Forbes J.M., et al. Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE). J Clin Invest 2001, 108:1853-1863.
    • (2001) J Clin Invest , vol.108 , pp. 1853-1863
    • Oldfield, M.D.1    Bach, L.A.2    Forbes, J.M.3
  • 19
    • 44449161800 scopus 로고    scopus 로고
    • Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat
    • Picard N., Baum O., Vogetseder A., Kaissling B., Le Hir M. Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat. Histochem Cell Biol 2008, 130:141-155.
    • (2008) Histochem Cell Biol , vol.130 , pp. 141-155
    • Picard, N.1    Baum, O.2    Vogetseder, A.3    Kaissling, B.4    Le Hir, M.5
  • 20
    • 0036318317 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies
    • Rastaldi M.P., Ferrario F., Giardino L., et al. Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies. Kidney Int 2002, 62:137-146.
    • (2002) Kidney Int , vol.62 , pp. 137-146
    • Rastaldi, M.P.1    Ferrario, F.2    Giardino, L.3
  • 21
    • 37049007816 scopus 로고    scopus 로고
    • An oral sorbent AST-120 increases renal NO synthesis in uremic rats
    • Tumur Z., Niwa T. An oral sorbent AST-120 increases renal NO synthesis in uremic rats. J Ren Nutr 2008, 18:60-64.
    • (2008) J Ren Nutr , vol.18 , pp. 60-64
    • Tumur, Z.1    Niwa, T.2
  • 22
    • 70849098235 scopus 로고    scopus 로고
    • An oral sorbent, AST-120, increases Klotho expression and inhibits cell senescence in the kidney of uremic rats
    • Adijiang A., Niwa T. An oral sorbent, AST-120, increases Klotho expression and inhibits cell senescence in the kidney of uremic rats. Am J Nephrol 2010, 31:160-164.
    • (2010) Am J Nephrol , vol.31 , pp. 160-164
    • Adijiang, A.1    Niwa, T.2
  • 23
    • 0020358296 scopus 로고
    • Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells
    • Greenburg G., Hay E.D. Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells. J Cell Biol 1989, 95:333-339.
    • (1989) J Cell Biol , vol.95 , pp. 333-339
    • Greenburg, G.1    Hay, E.D.2
  • 24
    • 77949351029 scopus 로고    scopus 로고
    • New insights into epithelial-mesenchymal transition in kidney fibrosis
    • Liu Y. New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 2010, 21:212-222.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 212-222
    • Liu, Y.1
  • 25
    • 0029806531 scopus 로고    scopus 로고
    • Transdifferentiation: a new angle on renal fibrosis
    • Strutz F., Muller G.A., Neilson E.G. Transdifferentiation: a new angle on renal fibrosis. Exp Nephrol 1996, 4:267-270.
    • (1996) Exp Nephrol , vol.4 , pp. 267-270
    • Strutz, F.1    Muller, G.A.2    Neilson, E.G.3
  • 26
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang J., Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 2001, 159:1465-1475.
    • (2001) Am J Pathol , vol.159 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 28
    • 0036324946 scopus 로고    scopus 로고
    • Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor
    • Jin M., Barron E., He S., Ryan S.J., Hinton D.R. Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor. Invest Ophthalmol Vis Sci 2002, 43:2782-2790.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 2782-2790
    • Jin, M.1    Barron, E.2    He, S.3    Ryan, S.J.4    Hinton, D.R.5
  • 29
    • 0029742425 scopus 로고    scopus 로고
    • Relationship between alpha-smooth muscle actin expression and fibrotic changes in human kidney
    • Boukhalfa G., Desmouliere A., Rondeau E., Gabbiani G., Sraer J.D. Relationship between alpha-smooth muscle actin expression and fibrotic changes in human kidney. Exp Nephrol 1996, 4:241-247.
    • (1996) Exp Nephrol , vol.4 , pp. 241-247
    • Boukhalfa, G.1    Desmouliere, A.2    Rondeau, E.3    Gabbiani, G.4    Sraer, J.D.5
  • 30
    • 0029117124 scopus 로고
    • Myofibroblasts and the progression of experimental glomerulonephritis
    • Zhang G., Moorhead P.J., el Nahas A.M. Myofibroblasts and the progression of experimental glomerulonephritis. Exp Nephrol 1995, 3:308-318.
    • (1995) Exp Nephrol , vol.3 , pp. 308-318
    • Zhang, G.1    Moorhead, P.J.2    el Nahas, A.M.3


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