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Volumn 155, Issue 5, 2014, Pages 1899-1907

Indoxyl Sulfate-Induced Activation of (Pro)Renin Receptor Is Involved in Expression of TGF-α1 and β-Smooth Muscle Actin in Proximal Tubular Cells

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALPHA SMOOTH MUSCLE ACTIN; AST 120; DIPHENYLIODONIUM SALT; I KAPPA B; INDICAN; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PRORENIN RECEPTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84899458357     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1937     Document Type: Article
Times cited : (47)

References (29)
  • 1
    • 0028466186 scopus 로고
    • Indoxyl sulfate, a circulating uremic toxin, stimulates the progression of glomerular sclerosis
    • Niwa T, Ise M. Indoxyl sulfate, a circulating uremic toxin, stimulates the progression of glomerular sclerosis. J Lab Clin Med. 1994; 124:96-104 (Pubitemid 2125685)
    • (1994) Journal of Laboratory and Clinical Medicine , vol.124 , Issue.1 , pp. 96-104
    • Niwa, T.1    Ise, M.2
  • 2
    • 0030723638 scopus 로고    scopus 로고
    • Indoxyl sulfate increases the gene expressions of TGF-β1,TIMP-1 and pro-a1 (I) collagen in uremic rat kidneys
    • Miyazaki T, IseM,Seo H,NiwaT. Indoxyl sulfate increases the gene expressions of TGF-β1, TIMP-1 and pro-a1(I) collagen in uremic rat kidneys. Kidney Int. 1997;62:S15-S22
    • (1997) Kidney Int. , vol.62
    • Miyazaki, T.1    Ise, M.2    Seo, H.3    Niwa, T.4
  • 4
    • 80054884869 scopus 로고    scopus 로고
    • NF-B plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells
    • Shimizu H, Bolati D, Adijiang A, et al. NF-B plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells. Am J Physiol Cell Physiol. 2011;301:C1201-C1212
    • (2011) Am J Physiol Cell Physiol. , vol.301
    • Shimizu, H.1    Bolati, D.2    Adijiang, A.3
  • 5
    • 78349295987 scopus 로고    scopus 로고
    • Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate
    • Shimizu H, Bolati D, Adijiang A, et al. Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate. Am J Physiol Cell Physiol. 2010;299: C1110-C1117
    • (2010) Am J Physiol Cell Physiol , vol.299
    • Shimizu, H.1    Bolati, D.2    Adijiang, A.3
  • 6
    • 84864812072 scopus 로고    scopus 로고
    • Stat3 contributes to indoxyl sulfate-induced inflammatory and fibrotic gene expression and cellular senescence
    • Shimizu H, Yisireyili M, Nishijima F, Niwa T. Stat3 contributes to indoxyl sulfate-induced inflammatory and fibrotic gene expression and cellular senescence. Am J Nephrol. 2012;36:184-189
    • (2012) Am J Nephrol , vol.36 , pp. 184-189
    • Shimizu, H.1    Yisireyili, M.2    Nishijima, F.3    Niwa, T.4
  • 7
    • 84878247681 scopus 로고    scopus 로고
    • CREB NF.-κB and NADPH oxidase coordinately upregulate indoxyl sul-fate-induced angiotensinogen expression in proximal tubular cells
    • Shimizu H, Saito S, Higashiyama Y, Nishijima F, Niwa T. CREB, NF-κB, and NADPH oxidase coordinately upregulate indoxyl sul- fate-induced angiotensinogen expression in proximal tubular cells. Am J Physiol Cell Physiol. 2013;304:C685-C692
    • (2013) Am J Physiol Cell Physiol. , vol.304
    • Shimizu, H.1    Saito, S.2    Higashiyama, Y.3    Nishijima, F.4    Niwa, T.5
  • 8
    • 84859111301 scopus 로고    scopus 로고
    • Indoxyl sulfate upregulates renal expression of MCP-1 via production of ROS and activation of NF-κB, p53, ERK, and JNK in proximal tubular cells
    • Shimizu H, Bolati D, Higashiyama Y, Nishijima F, Shimizu K, Niwa T. Indoxyl sulfate upregulates renal expression of MCP-1 via production of ROS and activation of NF-κB, p53, ERK, and JNK in proximal tubular cells. Life Sci. 2012;90:525-530
    • (2012) Life Sci , vol.90 , pp. 525-530
    • Shimizu, H.1    Bolati, D.2    Higashiyama, Y.3    Nishijima, F.4    Shimizu, K.5    Niwa, T.6
  • 9
    • 78650684104 scopus 로고    scopus 로고
    • Indoxyl sulfate reduces klotho expression and promotes senescence in the kidneys of hypertensive rats
    • Adijiang A, Shimizu H, Higuchi Y, Nishijima F, Niwa T. Indoxyl sulfate reduces klotho expression and promotes senescence in the kidneys of hypertensive rats. J Ren Nutr. 2011;21:105-109
    • (2011) J Ren Nutr , vol.21 , pp. 105-109
    • Adijiang, A.1    Shimizu, H.2    Higuchi, Y.3    Nishijima, F.4    Niwa, T.5
  • 10
    • 84872281329 scopus 로고    scopus 로고
    • Indoxyl sulfate upregulates renal expression of ICAM-1 via production of ROS and activation of NF-κB and p53 in proximal tubular cells
    • Shimizu H, Yisireyili M, Higashiyama Y, Nishijima F, Niwa T. Indoxyl sulfate upregulates renal expression of ICAM-1 via production of ROS and activation of NF-κB and p53 in proximal tubular cells. Life Sci. 2013;92:143-148
    • (2013) Life Sci , vol.92 , pp. 143-148
    • Shimizu, H.1    Yisireyili, M.2    Higashiyama, Y.3    Nishijima, F.4    Niwa, T.5
  • 11
    • 84873030568 scopus 로고    scopus 로고
    • Indoxyl sulfate enhances p53-TGF-β1-Smad3 pathway in proximal tubular cells
    • Shimizu H, Yisireyili M, Nishijima F, Niwa T. Indoxyl sulfate enhances p53-TGF-β1-Smad3 pathway in proximal tubular cells. Am J Nephrol. 2013;37:97-103
    • (2013) Am J Nephrol , vol.37 , pp. 97-103
    • Shimizu, H.1    Yisireyili, M.2    Nishijima, F.3    Niwa, T.4
  • 12
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • DOI 10.1172/JCI200214276
    • Nguyen G, Delarue F, Burcklé C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest. 2002;109:1417- 1427 (Pubitemid 34596167)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.11 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.-D.6
  • 13
    • 30944469631 scopus 로고    scopus 로고
    • Renin increases mesangial cell transforming growth factor-β1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
    • DOI 10.1038/sj.ki.5000011, PII 5000011
    • Huang Y, Wongamorntham S, Kasting J, et al. Renin increases mesangial cell transforming growth factor-β1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int. 2006;69:105-113 (Pubitemid 43117745)
    • (2006) Kidney International , vol.69 , Issue.1 , pp. 105-113
    • Huang, Y.1    Wongamorntham, S.2    Kasting, J.3    McQuillan, D.4    Owens, R.T.5    Yu, L.6    Noble, N.A.7    Border, W.8
  • 14
    • 34548483245 scopus 로고    scopus 로고
    • The (Pro)renin receptor and the kidney
    • DOI 10.1016/j.semnephrol.2007.07.005, PII S0270929507000903, Hypertension and the kidney: New Avenues for an Improved Management of Hypertension in Renal Diseases
    • Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Itoh H. The (pro)renin receptor and the kidney. Semin Nephrol. 2007;27:524- 528 (Pubitemid 47374903)
    • (2007) Seminars in Nephrology , vol.27 , Issue.5 , pp. 524-528
    • Ichihara, A.1    Kaneshiro, Y.2    Takemitsu, T.3    Sakoda, M.4    Itoh, H.5
  • 15
    • 0029853814 scopus 로고    scopus 로고
    • Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen
    • Nguyen G, Delarue F, Berrou J, Rondeau E, Sraer JD. Specific receptor binding of renin onhumanmesangial cells in culture increases plasminogen activator inhibitor-1 antigen. Kidney Int. 1996;50: 1897-1903 (Pubitemid 26417532)
    • (1996) Kidney International , vol.50 , Issue.6 , pp. 1897-1903
    • Nguyen, G.1    Delarue, F.2    Berrou, J.3    Rondeau, E.4    Sraer, J.-D.5
  • 16
    • 34347350179 scopus 로고    scopus 로고
    • Renin-stimulated TGF-β1 expression is regulated by a mitogen-activated protein kinase in mesangial cells
    • DOI 10.1038/sj.ki.5002243, PII 5002243
    • Huang Y, Noble NA, Zhang J, Xu C, Border WA. Renin-stimulated TGF-β1 expression is regulated by a mitogen-activated protein kinase in mesangial cells. Kidney Int. 2007;72:45-52 (Pubitemid 47014443)
    • (2007) Kidney International , vol.72 , Issue.1 , pp. 45-52
    • Huang, Y.1    Noble, N.A.2    Zhang, J.3    Xu, C.4    Border, W.A.5
  • 19
    • 71349085194 scopus 로고    scopus 로고
    • Increased expression of (pro) renin receptor in the remnant kidneys of 5/6 nephrectomized rats
    • Hirose T, Mori N, Totsune K, et al. Increased expression of (pro) renin receptor in the remnant kidneys of 5/6 nephrectomized rats. Regul Pept. 2010;159:93-99
    • (2010) Regul Pept , vol.159 , pp. 93-99
    • Hirose, T.1    Mori, N.2    Totsune, K.3
  • 20
    • 0021943664 scopus 로고
    • Application of immunochemical methods to the identification and characterization of rat kidney inactive renin
    • Takii Y, Figueiredo AF, Inagami T. Application of immunochemical methods to the identification and characterization of rat kidney inactive renin. Hypertension. 1985;7:236-243 (Pubitemid 15093649)
    • (1985) Hypertension , vol.7 , Issue.2 , pp. 236-243
    • Takii, Y.1    Figueiredo, A.F.S.2    Inagami, T.3
  • 21
    • 84855175734 scopus 로고    scopus 로고
    • AST-120 ameliorates epithelial-tomesenchymal transition and interstitial fibrosis in the kidneys of chronic kidney disease rats
    • Bolati D, Shimizu H, Niwa T. AST-120 ameliorates epithelial-tomesenchymal transition and interstitial fibrosis in the kidneys of chronic kidney disease rats. J Ren Nutr. 2012;22:176-180
    • (2012) J Ren Nutr , vol.22 , pp. 176-180
    • Bolati, D.1    Shimizu, H.2    Niwa, T.3
  • 23
    • 0030663544 scopus 로고    scopus 로고
    • The protein metabolite hypothesis, a model for the progression of renal failure: An oral adsorbent lowers indoxyl sulfate levels in undialyzed uremic patients
    • Niwa T, Nomura T, Sugiyama S, Miyazaki T, Tsukushi S, Tsutsui S. The protein metabolite hypothesis, a model for the progression of renal failure: an oral adsorbent lowers indoxyl sulfate levels in undialyzed uremic patients. Kidney Int. 1997;52(suppl 62):S23-S28 (Pubitemid 27489396)
    • (1997) Kidney International, Supplement , vol.51 , Issue.62
    • Niwa, T.1    Nomura, T.2    Sugiyama, S.3    Miyazaki, T.4    Tsukushi, S.5    Tsutsui, S.6
  • 24
    • 84856271704 scopus 로고    scopus 로고
    • Sodium depletion enhances renal expression of (pro)renin receptor via cyclic GMP-protein kinase G signaling pathway
    • Huang J, Siragy HM. Sodium depletion enhances renal expression of (pro)renin receptor via cyclic GMP-protein kinase G signaling pathway. Hypertension. 2012;59:317-323
    • (2012) Hypertension. , vol.59 , pp. 317-323
    • Huang, J.1    Siragy, H.M.2
  • 25
    • 79953227634 scopus 로고    scopus 로고
    • Soluble form of the (pro)renin receptor is augmented in the collecting duct and urine of chronic angiotensin II-dependent hypertensive rats
    • Gonzalez AA, Lara LS, Luffman C, Seth DM, Prieto MC. Soluble form of the (pro)renin receptor is augmented in the collecting duct and urine of chronic angiotensin II-dependent hypertensive rats. Hypertension. 2011;57:859-864
    • (2011) Hypertension , vol.57 , pp. 859-864
    • Gonzalez, A.A.1    Lara, L.S.2    Luffman, C.3    Seth, D.M.4    Prieto, M.C.5
  • 27
    • 0036033161 scopus 로고    scopus 로고
    • The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation
    • DOI 10.1016/S0006-291X(02)02291-X, PII S0006291X0202291X
    • Yamamoto T, Sekine Y, Kashima K, et al. The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation. Biochem Biophys Res Commun. 2002;297:811-817 (Pubitemid 35230323)
    • (2002) Biochemical and Biophysical Research Communications , vol.297 , Issue.4 , pp. 811-817
    • Yamamoto, T.1    Sekine, Y.2    Kashima, K.3    Kubota, A.4    Sato, N.5    Aoki, N.6    Matsuda, T.7
  • 28
    • 84873057372 scopus 로고    scopus 로고
    • Evolving concepts on regulation and function of renin in distal nephron
    • Prieto MC, Gonzalez AA, Navar LG. Evolving concepts on regulation and function of renin in distal nephron. Pflugers Arch. 2013; 465:121-132
    • (2013) Pflugers Arch , vol.465 , pp. 121-132
    • Prieto, M.C.1    Gonzalez, A.A.2    Navar, L.G.3
  • 29
    • 84881640491 scopus 로고    scopus 로고
    • Overexpression of Renin in the collecting duct causes elevated blood pressure
    • Ramkumar N, Ying J, Stuart D, Kohan DE. Overexpression of Renin in the collecting duct causes elevated blood pressure. Am J Hypertens. 2013;26:965-972
    • (2013) Am J Hypertens , vol.26 , pp. 965-972
    • Ramkumar, N.1    Ying, J.2    Stuart, D.3    Kohan, D.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.