Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2

FEBS Journal

Volumn 276, Issue 24, 2009, Pages 7237-7252

  Nakagawa, Hiroshi ^a   Wakabayashi Nakao, Kanako ^a   Tamura, Ai ^a   Toyoda, Yu ^a   Koshiba, Shoko ^a   Ishikawa, Toshihisa ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

ABC transporter; ABCG2; N linked glycosylation; Proteasome; Ubiquitin

Indexed keywords

1 DEOXYMANNONOJIRIMYCIN; 1 DEOXYNOJIRIMYCIN; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; ABC TRANSPORTER; ASPARAGINE; ATP BINDING CASSETTE TRANSPORTER ABCG2 VARIANT N596Q; BAFILOMYCIN A1; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BREAST CANCER RESISTANCE PROTEIN; BREFELDIN A; CASTANOSPERMINE; COMPLEMENTARY DNA; GENOMIC DNA; GLUTAMINE; GLYCAN; HOMODIMER; MONOMER; PROTEASOME; SWAINSONINE; TUNICAMYCIN; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CELL LYSATE; CELL MEMBRANE; DISULFIDE BOND; ENZYME ASSAY; ENZYME DEGRADATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; INTRACELLULAR MEMBRANE; LYSOSOME; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN STABILITY; PROTEIN SYNTHESIS INHIBITION; PROTEIN VARIANT; QUANTITATIVE ANALYSIS; UBIQUITINATION; WILD TYPE;

1-DEOXYNOJIRIMYCIN; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ASPARAGINE; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; GLUCOSAMINE; GLYCOSYLATION; HUMANS; INDOLIZINES; LEUPEPTINS; MACROLIDES; MANNOSYL-GLYCOPROTEIN ENDO-BETA-N-ACETYLGLUCOSAMINIDASE; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; PROTEASOME ENDOPEPTIDASE COMPLEX; SEQUENCE ALIGNMENT; TUNICAMYCIN; UBIQUITIN;

EID: 71949113235     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07423.x     Document Type: Article

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