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Volumn 5, Issue 4, 2014, Pages

Rho gtpases masters of cell migration

Author keywords

Cell migration; Microenvironment; Rho GTPases

Indexed keywords

PROTEIN CDC42; RAC PROTEIN; RHO FACTOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; RHOBTB GUANINE NUCLEOTIDE BINDING PROTEIN; RHOD GUANINE NUCLEOTIDE BINDING PROTEIN; RHOF GUANINE NUCLEOTIDE BINDING PROTEIN; RHOH GUANINE NUCLEOTIDE BINDING PROTEIN; RHOJ GUANINE NUCLEOTIDE BINDING PROTEIN; RHOQ GUANINE NUCLEOTIDE BINDING PROTEIN; RHOU GUANINE NUCLEOTIDE BINDING PROTEIN; RHOV GUANINE NUCLEOTIDE BINDING PROTEIN; RND1 GUANINE NUCLEOTIDE BINDING PROTEIN; RND2 GUANINE NUCLEOTIDE BINDING PROTEIN; RND3 GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; ACTIN;

EID: 84908424942     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.29710     Document Type: Article
Times cited : (178)

References (79)
  • 1
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • PMID:16212495;
    • Jaffe AB, Hall A. Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 2005; 21:247-69; PMID:16212495; http://dx.doi.org/10.1146/annurev.cellbio.21.020604.150721
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 2
    • 34249018367 scopus 로고    scopus 로고
    • GEFs and GAPs: Critical elements in the control of small G proteins
    • PMID:17540168;
    • Bos JL, Rehmann H, Wittinghofer A. GEFs and GAPs: critical elements in the control of small G proteins. Cell 2007; 129:865-77; PMID:17540168; http://dx.doi.org/10.1016/j.cell.2007.05.018
    • (2007) Cell , vol.129 , pp. 865-877
    • Bos, J.L.1    Rehmann, H.2    Wittinghofer, A.3
  • 3
    • 79960706295 scopus 로고    scopus 로고
    • The ‘invisible hand’: Regulation of RHO GTPases by RHOGDIs
    • PMID:21779026;
    • Garcia-Mata R, Boulter E, Burridge K. The ‘invisible hand’: regulation of RHO GTPases by RHOGDIs. Nat Rev Mol Cell Biol 2011; 12:493-504; PMID:21779026; http://dx.doi.org/10.1038/ nrm3153
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 493-504
    • Garcia-Mata, R.1    Boulter, E.2    Burridge, K.3
  • 4
    • 84876937357 scopus 로고    scopus 로고
    • .14-3-3 proteins interact with a hybrid prenylphosphorylation motif to inhibit G proteins
    • PMID:23622247;
    • Riou P, Kjær S, Garg R, Purkiss A, George R, Cain RJ, Bineva G, Reymond N, McColl B, Thompson AJ, et al. 14-3-3 proteins interact with a hybrid prenylphosphorylation motif to inhibit G proteins. Cell 2013; 153:640-53; PMID:23622247; http://dx.doi.org/10.1016/j.cell.2013.03.044
    • (2013) Cell , vol.153 , pp. 640-653
    • Riou, P.1    Kjær, S.2    Garg, R.3    Purkiss, A.4    George, R.5    Cain, R.J.6    Bineva, G.7    Reymond, N.8    McColl, B.9    Thompson, A.J.10
  • 5
    • 84870209800 scopus 로고    scopus 로고
    • Rho family GTPases
    • PMID:23176484;
    • Hall A. Rho family GTPases. Biochem Soc Trans 2012; 40:1378-82; PMID:23176484; http://dx.doi.org/10.1042/BST20120103
    • (2012) Biochem Soc Trans , vol.40 , pp. 1378-1382
    • Hall, A.1
  • 6
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • PMID:1643658;
    • Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 1992; 70:401-10; PMID:1643658; http://dx.doi.org/10.1016/0092-8674(92)90164-8
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 7
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actinstress fibers in response to growth factors
    • PMID:1643657;
    • Ridley AJ, Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actinstress fibers in response to growth factors. Cell 1992; 70:389-99; PMID:1643657; http://dx.doi.org/10.1016/0092-8674(92)90163-7
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 8
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regu-late the assembly of multimolecular focal complexesassociated with actin stress fibers, lamellipodia, and filopodia
    • PMID:7536630;
    • Nobes CD, Hall A. Rho, rac, and cdc42 GTPases regu-late the assembly of multimolecular focal complexesassociated with actin stress fibers, lamellipodia, and filopodia. Cell 1995; 81:53-62; PMID:7536630; http:// dx.doi.org/10.1016/0092-8674(95)90370-4
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 9
    • 0037102301 scopus 로고    scopus 로고
    • Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
    • PMID:12181570;
    • Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW. Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck. Nature 2002; 418:790-3; PMID:12181570; http://dx.doi.org/10.1038/nature00859
    • (2002) Nature , vol.418 , pp. 790-793
    • Eden, S.1    Rohatgi, R.2    Podtelejnikov, A.V.3    Mann, M.4    Kirschner, M.W.5
  • 11
    • 0042674398 scopus 로고    scopus 로고
    • RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
    • PMID:12879077;
    • Katoh H, Negishi M. RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature 2003; 424:461-4; PMID:12879077; http://dx.doi.org/10.1038/nature01817
    • (2003) Nature , vol.424 , pp. 461-464
    • Katoh, H.1    Negishi, M.2
  • 12
    • 0033574722 scopus 로고    scopus 로고
    • The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
    • PMID:10219243;
    • Rohatgi R, Ma L, Miki H, Lopez M, Kirchhausen T, Takenawa T, Kirschner MW. The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell 1999; 97:221-31; PMID:10219243; http://dx.doi.org/10.1016/S00928674(00)80732-1
    • (1999) Cell , vol.97 , pp. 221-231
    • Rohatgi, R.1    Ma, L.2    Miki, H.3    Lopez, M.4    Kirchhausen, T.5    Takenawa, T.6    Kirschner, M.W.7
  • 15
    • 68549122708 scopus 로고    scopus 로고
    • Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
    • PMID:19160018;
    • Narumiya S, Tanji M, Ishizaki T. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Rev 2009; 28:65-76; PMID:19160018; http://dx.doi.org/10.1007/s10555008-9170-7
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 65-76
    • Narumiya, S.1    Tanji, M.2    Ishizaki, T.3
  • 16
    • 33646197411 scopus 로고    scopus 로고
    • Spatio-temporal dynamics of RhoA activity in migrating cells
    • PMID:16547516;
    • Pertz O, Hodgson L, Klemke RL, Hahn KM. Spatio-temporal dynamics of RhoA activity in migrating cells. Nature 2006; 440:1069-72; PMID:16547516; http://dx.doi.org/10.1038/nature04665
    • (2006) Nature , vol.440 , pp. 1069-1072
    • Pertz, O.1    Hodgson, L.2    Klemke, R.L.3    Hahn, K.M.4
  • 17
    • 69949185998 scopus 로고    scopus 로고
    • Nalbant P, Abell A, Johnson GL, Hahn KM, Danuser  G. Coordination of Rho GTPase activities during cell protrusion
    • PMID:19693013;
    • Machacek M, Hodgson L, Welch C, Elliott H, Pertz O,  Nalbant P, Abell A, Johnson GL, Hahn KM, Danuser  G. Coordination of Rho GTPase activities during cell protrusion. Nature 2009; 461:99-103; PMID:19693013; http://dx.doi.org/10.1038/ nature08242
    • (2009) Nature , vol.461 , pp. 99-103
    • Machacek, M.1    Hodgson, L.2    Welch, C.3    Elliott, H.4    Pertz, O.5
  • 18
    • 0345731237 scopus 로고    scopus 로고
    • Rho GTPases lead the way
    • PMID:14697350;
    • Raftopoulou M, Hall A. Cell migration: Rho GTPases lead the way. Dev Biol 2004; 265:23-32; PMID:14697350; http://dx.doi.org/10.1016/j.ydbio.2003.06.003
    • (2004) Dev Biol , vol.265 , pp. 23-32
    • Raftopoulou, M.1    Migration, H.A.C.2
  • 19
    • 79958232399 scopus 로고    scopus 로고
    • RhoA and RhoC have distinct roles in migration and invasion by acting through different targets
    • PMID:21576392;
    • Vega FM, Fruhwirth G, Ng T, Ridley AJ. RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. J Cell Biol 2011; 193:655-65; PMID:21576392; http://dx.doi.org/10.1083/jcb.201011038
    • (2011) J Cell Biol , vol.193 , pp. 655-665
    • Vega, F.M.1    Fruhwirth, G.2    Ng, T.3    Ridley, A.J.4
  • 20
    • 79955382980 scopus 로고    scopus 로고
    • RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts
    • PMID:21454503;
    • Melendez J, Stengel K, Zhou X, Chauhan BK, Debidda M, Andreassen P, Lang RA, Zheng Y. RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts. J Biol Chem 2011; 286:15132-7; PMID:21454503; http://dx.doi.org/10.1074/jbc.C111.229336
    • (2011) J Biol Chem , vol.286 , pp. 15132-15137
    • Melendez, J.1    Stengel, K.2    Zhou, X.3    Chauhan, B.K.4    Debidda, M.5    Reassen, P.6    Lang, R.A.7    Zheng, Y.8
  • 21
    • 0026612457 scopus 로고
    • Intracellular localization of the P21rho proteins
    • PMID:1383236;
    • Adamson P, Paterson HF, Hall A. Intracellular localization of the P21rho proteins. J Cell Biol 1992; 119:617-27; PMID:1383236; http://dx.doi.org/10.1083/jcb.119.3.617
    • (1992) J Cell Biol , vol.119 , pp. 617-627
    • Adamson, P.1    Paterson, H.F.2    Hall, A.3
  • 22
    • 0036714174 scopus 로고    scopus 로고
    • Small interfering RNAs as a tool to assign Rho GTPase exchange-factor function in vivo
    • PMID:12113653;
    • Gampel A, Mellor H. Small interfering RNAs as a tool to assign Rho GTPase exchange-factor function in vivo. Biochem J 2002; 366:393-8; PMID:12113653; http://dx.doi.org/10.1042/BJ20020844
    • (2002) Biochem J , vol.366 , pp. 393-398
    • Gampel, A.1    Mellor, H.2
  • 23
    • 0033539150 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB
    • PMID:10508588;
    • Gampel A, Parker PJ, Mellor H. Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB. Curr Biol 1999; 9:955-8; PMID:10508588; http://dx.doi.org/10.1016/S0960-9822(99)80422-9
    • (1999) Curr Biol , vol.9 , pp. 955-958
    • Gampel, A.1    Parker, P.J.2    Mellor, H.3
  • 24
    • 34548384688 scopus 로고    scopus 로고
    • ROCK I-mediated activation of NFkappaB by RhoB
    • PMID:17728102;
    • Rodriguez PL, Sahay S, Olabisi OO, Whitehead IP. ROCK I-mediated activation of NFkappaB by RhoB. Cell Signal 2007; 19:2361-9; PMID:17728102; http://dx.doi.org/10.1016/j.cellsig.2007.07.021
    • (2007) Cell Signal , vol.19 , pp. 2361-2369
    • Rodriguez, P.L.1    Sahay, S.2    Olabisi, O.O.3    Whitehead, I.P.4
  • 25
    • 84864819464 scopus 로고    scopus 로고
    • RhoB regulates uPAR signalling
    • PMID:22366462;
    • Alfano D, Ragno P, Stoppelli MP, Ridley AJ. RhoB regulates uPAR signalling. J Cell Sci 2012; 125:2369-80; PMID:22366462; http://dx.doi.org/10.1242/jcs.091579
    • (2012) J Cell Sci , vol.125 , pp. 2369-2380
    • Alfano, D.1    Ragno, P.2    Stoppelli, M.P.3    Ridley, A.J.4
  • 26
    • 50249145697 scopus 로고    scopus 로고
    • UPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180
    • PMID:18725541;
    • Smith HW, Marra P, Marshall CJ. uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180. J Cell Biol 2008; 182:777-90; PMID:18725541; http://dx.doi.org/10.1083/jcb.200712050
    • (2008) J Cell Biol , vol.182 , pp. 777-790
    • Smith, H.W.1    Marra, P.2    Marshall, C.J.3
  • 27
    • 75749146306 scopus 로고    scopus 로고
    • Plasticity of cell migration: A multi-scale tuning model
    • PMID:19951899;
    • Friedl P, Wolf K. Plasticity of cell migration: a multi-scale tuning model. J Cell Biol 2010; 188:11-9; PMID:19951899; http://dx.doi.org/10.1083/jcb.200909003
    • (2010) J Cell Biol , vol.188 , pp. 11-19
    • Friedl, P.1    Wolf, K.2
  • 28
    • 12344252751 scopus 로고    scopus 로고
    • Mechanisms of cancer cell invasion
    • PMID:15661538;
    • Sahai E. Mechanisms of cancer cell invasion. Curr Opin Genet Dev 2005; 15:87-96; PMID:15661538; http://dx.doi.org/10.1016/j.gde.2004.12.002
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 87-96
    • Sahai, E.1
  • 29
    • 54549088877 scopus 로고    scopus 로고
    • Rac activation and inactivation control plasticity of tumor cell movement
    • PMID:18984162;
    • Sanz-Moreno V, Gadea G, Ahn J, Paterson H, Marra P, Pinner S, Sahai E, Marshall CJ. Rac activation and inactivation control plasticity of tumor cell movement. Cell 2008; 135:510-23; PMID:18984162; http://dx. doi.org/10.1016/j.cell.2008.09.043
    • (2008) Cell , vol.135 , pp. 510-523
    • Sanz-Moreno, V.1    Gadea, G.2    Ahn, J.3    Paterson, H.4    Marra, P.5    Pinner, S.6    Sahai, E.7    Marshall, C.J.8
  • 31
    • 14744304060 scopus 로고    scopus 로고
    • Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion
    • PMID:15723050;
    • Wilkinson S, Paterson HF, Marshall CJ. Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion. Nat Cell Biol 2005; 7:255-61; PMID:15723050; http://dx.doi.org/10.1038/ncb1230
    • (2005) Nat Cell Biol , vol.7 , pp. 255-261
    • Wilkinson, S.1    Paterson, H.F.2    Marshall, C.J.3
  • 32
    • 53249143863 scopus 로고    scopus 로고
    • DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells
    • PMID:18835169;
    • Gadea G, Sanz-Moreno V, Self A, Godi A, Marshall CJ. DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells. Curr Biol 2008; 18:1456-65; PMID:18835169; http://dx.doi.org/10.1016/j.cub.2008.08.053
    • (2008) Curr Biol , vol.18 , pp. 1456-1465
    • Gadea, G.1    Sanz-Moreno, V.2    Self, A.3    Godi, A.4    Marshall, C.J.5
  • 33
    • 36749013537 scopus 로고    scopus 로고
    • Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
    • PMID:18037882;
    • Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K, Sahai E. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 2007; 9:1392-400; PMID:18037882; http://dx.doi.org/10.1038/ncb1658
    • (2007) Nat Cell Biol , vol.9 , pp. 1392-1400
    • Gaggioli, C.1    Hooper, S.2    Hidalgo-Carcedo, C.3    Grosse, R.4    Marshall, J.F.5    Harrington, K.6    Sahai, E.7
  • 34
    • 84876590830 scopus 로고    scopus 로고
    • New insight into the molecular switch mechanism of human  Rho family proteins: Shifting a paradigm
    • PMID:23096567;
    • Jaiswal M, Fansa EK, Dvorsky R, Ahmadian MR. New insight into the molecular switch mechanism of human  Rho family proteins: shifting a paradigm. Biol Chem 2013; 394:89-95; PMID:23096567; http://dx.doi.org/10.1515/hsz-2012-0207
    • (2013) Biol Chem , vol.394 , pp. 89-95
    • Jaiswal, M.1    Fansa, E.K.2    Dvorsky, R.3    Ahmadian, M.R.4
  • 35
    • 12544253725 scopus 로고    scopus 로고
    • The Rho family GTPase Rif induces filopodia through mDia2
    • PMID:15668168;
    • Pellegrin S, Mellor H. The Rho family GTPase Rif induces filopodia through mDia2. Curr Biol 2005; 15:129-33; PMID:15668168; http://dx.doi.org/10.1016/j.cub.2005.01.011
    • (2005) Curr Biol , vol.15 , pp. 129-133
    • Pellegrin, S.1    Mellor, H.2
  • 36
    • 84856945929 scopus 로고    scopus 로고
    • MDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation
    • PMID:22179776;
    • Goh WI, Lim KB, Sudhaharan T, Sem KP, Bu W, Chou AM, Ahmed S. mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation. J Biol Chem 2012; 287:4702-14; PMID:22179776; http://dx.doi.org/10.1074/jbc.M111.305102
    • (2012) J Biol Chem , vol.287 , pp. 4702-4714
    • Goh, W.I.1    Lim, K.B.2    Sudhaharan, T.3    Sem, K.P.4    Bu, W.5    Chou, A.M.6    Ahmed, S.7
  • 37
    • 77951191158 scopus 로고    scopus 로고
    • The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells
    • PMID:20233848;
    • Fan L, Pellegrin S, Scott A, Mellor H. The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells. J Cell Sci 2010; 123:1247-52; PMID:20233848; http://dx.doi.org/10.1242/jcs.061754
    • (2010) J Cell Sci , vol.123 , pp. 1247-1252
    • Fan, L.1    Pellegrin, S.2    Scott, A.3    Mellor, H.4
  • 39
    • 0037341806 scopus 로고    scopus 로고
    • RhoD regulates endosome dynamics through Diaphanous-related For-min and Src tyrosine kinase
    • PMID:12577064;
    • Gasman S, Kalaidzidis Y, Zerial M. RhoD regulates endosome dynamics through Diaphanous-related For-min and Src tyrosine kinase. Nat Cell Biol 2003; 5:195-204; PMID:12577064; http://dx.doi.org/10.1038/ncb935
    • (2003) Nat Cell Biol , vol.5 , pp. 195-204
    • Gasman, S.1    Kalaidzidis, Y.2    Zerial, M.3
  • 40
    • 0033561496 scopus 로고    scopus 로고
    • Small GTPase RhoD suppresses cell migration and cytokinesis
    • PMID:10229194;
    • Tsubakimoto K, Matsumoto K, Abe H, Ishii J, Amano M, Kaibuchi K, Endo T. Small GTPase RhoD suppresses cell migration and cytokinesis. Oncogene 1999; 18:2431-40; PMID:10229194; http://dx.doi.org/10.1038/sj.onc.1202604
    • (1999) Oncogene , vol.18 , pp. 2431-2440
    • Tsubakimoto, K.1    Matsumoto, K.2    Abe, H.3    Ishii, J.4    Amano, M.5    Kaibuchi, K.6    Endo, T.7
  • 41
    • 84871253887 scopus 로고    scopus 로고
    • RhoD regulates cytoskeletal dynamics via the actin nucleation-promoting factor WASp homologue associated with actin Golgi membranes and microtubules
    • PMID:23087206;
    • Gad AK, Nehru V, Ruusala A, Aspenstrom P. RhoD regulates cytoskeletal dynamics via the actin nucleation-promoting factor WASp homologue associated with actin Golgi membranes and microtubules. Mol Biol Cell 2012; 23:4807-19; PMID:23087206; http://dx.doi.org/10.1091/mbc.E12-07-0555
    • (2012) Mol Biol Cell , vol.23 , pp. 4807-4819
    • Gad, A.K.1    Nehru, V.2    Ruusala, A.3    Aspenstrom, P.4
  • 42
    • 84877642787 scopus 로고    scopus 로고
    • Interaction of RhoD and ZIP kinase modulates actin filament assembly and focal adhesion dynamics
    • PMID:23454120;
    • Nehru V, Almeida FN, Aspenstrom P. Interaction of RhoD and ZIP kinase modulates actin filament assembly and focal adhesion dynamics. Biochem Biophys Res Commun 2013; 433:163-9; PMID:23454120; http://dx.doi.org/10.1016/j.bbrc.2013.02.046
    • (2013) Biochem Biophys Res Commun , vol.433 , pp. 163-169
    • Nehru, V.1    Almeida, F.N.2    Aspenstrom, P.3
  • 43
    • 0037242248 scopus 로고    scopus 로고
    • Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth
    • PMID:12456725;
    • Abe T, Kato M, Miki H, Takenawa T, Endo T. Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth. J Cell Sci 2003; 116:155-68; PMID:12456725; http://dx.doi.org/10.1242/jcs.00208
    • (2003) J Cell Sci , vol.116 , pp. 155-168
    • Abe, T.1    Kato, M.2    Miki, H.3    Takenawa, T.4    Endo, T.5
  • 45
    • 84885414840 scopus 로고    scopus 로고
    • Rho GTPases and regulation of cell migration and polarization in human corneal epithelial cells
    • PMID:24130842;
    • Hou A, Toh LX, Gan KH, Lee KJ, Manser E, Tong L. Rho GTPases and regulation of cell migration and polarization in human corneal epithelial cells. PLoS One 2013; 8:e77107; PMID:24130842; http://dx.doi. org/10.1371/journal.pone.0077107
    • (2013) Plos One , vol.8
    • Hou, A.1    Toh, L.X.2    Gan, K.H.3    Lee, K.J.4    Manser, E.5    Tong, L.6
  • 46
    • 77958198472 scopus 로고    scopus 로고
    • Rnd proteins: Multifunctional regulators of the cytoskeleton and cell cycle progression
    • PMID:20836090;
    • Riou P, Villalonga P, Ridley AJ. Rnd proteins: multifunctional regulators of the cytoskeleton and cell cycle progression. Bioessays 2010; 32:986-92; PMID:20836090; http://dx.doi.org/10.1002/ bies.201000060
    • (2010) Bioessays , vol.32 , pp. 986-992
    • Riou, P.1    Villalonga, P.2    Ridley, A.J.3
  • 48
    • 78650512223 scopus 로고    scopus 로고
    • Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
    • PMID:21170030;
    • Hidalgo-Carcedo C, Hooper S, Chaudhry SI, Williamson P, Harrington K, Leitinger B, Sahai E. Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6. Nat Cell Biol 2011; 13:49-58; PMID:21170030; http://dx.doi.org/10.1038/ncb2133
    • (2011) Nat Cell Biol , vol.13 , pp. 49-58
    • Hidalgo-Carcedo, C.1    Hooper, S.2    Chaudhry, S.I.3    Williamson, P.4    Harrington, K.5    Leitinger, B.6    Sahai, E.7
  • 49
    • 84965027070 scopus 로고    scopus 로고
    • Rnd3 induces stress fibres in endothelial cells through RhoB
    • PMID:23430146;
    • Gottesbuhren U, Garg R, Riou P, McColl B, Brayson D, Ridley AJ. Rnd3 induces stress fibres in endothelial cells through RhoB. Biol Open 2013; 2:210-6; PMID:23430146; http://dx.doi.org/10.1242/ bio.20123574
    • (2013) Biol Open , vol.2 , pp. 210-216
    • Gottesbuhren, U.1    Garg, R.2    Riou, P.3    McColl, B.4    Brayson, D.5    Ridley, A.J.6
  • 50
    • 33744549035 scopus 로고    scopus 로고
    • Pragmin, a novel effector of Rnd2 GTPase, stimulates RhoA activity
    • PMID:16481321;
    • Tanaka H, Katoh H, Negishi M. Pragmin, a novel effector of Rnd2 GTPase, stimulates RhoA activity. J Biol Chem 2006; 281:10355-64; PMID:16481321; http://dx.doi.org/10.1074/jbc.M511314200
    • (2006) J Biol Chem , vol.281 , pp. 10355-10364
    • Tanaka, H.1    Katoh, H.2    Negishi, M.3
  • 51
    • 84859731404 scopus 로고    scopus 로고
    • Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation
    • PMID:22357615;
    • Oinuma I, Kawada K, Tsukagoshi K, Negishi M. Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation. Mol Biol Cell 2012; 23:1593-604; PMID:22357615; http://dx.doi.org/10.1091/ mbc.E11-11-0900
    • (2012) Mol Biol Cell , vol.23 , pp. 1593-1604
    • Oinuma, I.1    Kawada, K.2    Tsukagoshi, K.3    Negishi, M.4
  • 52
    • 44449178868 scopus 로고    scopus 로고
    • Rho GTPases in cancer cell biology
    • PMID:18460342;
    • Vega FM, Ridley AJ. Rho GTPases in cancer cell biology. FEBS Lett 2008; 582:2093-101; PMID:18460342; http://dx.doi.org/10.1016/j.febslet. 2008.04.039
    • (2008) FEBS Lett , vol.582 , pp. 2093-2101
    • Vega, F.M.1    Ridley, A.J.2
  • 53
    • 0036150120 scopus 로고    scopus 로고
    • The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function
    • PMID:11809807;
    • Li X, Bu X, Lu B, Avraham H, Flavell RA, Lim B. The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function. Mol Cell Biol 2002; 22:1158-71; PMID:11809807; http://dx.doi. org/10.1128/MCB.22.4.1158-1171.2002
    • (2002) Mol Cell Biol , vol.22 , pp. 1158-1171
    • Li, X.1    Bu, X.2    Lu, B.3    Avraham, H.4    Flavell, R.A.5    Lim, B.6
  • 54
    • 13544249617 scopus 로고    scopus 로고
    • RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration, and engraftment of hematopoietic progenitor cells
    • PMID:15494435;
    • Gu Y, Jasti AC, Jansen M, Siefring JE. RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration, and engraftment of hematopoietic progenitor cells. Blood 2005; 105:1467-75; PMID:15494435; http://dx.doi.org/10.1182/blood2004-04-1604
    • (2005) Blood , vol.105 , pp. 1467-1475
    • Gu, Y.1    Jasti, A.C.2    Jansen, M.3    Siefring, J.E.4
  • 55
    • 41949097347 scopus 로고    scopus 로고
    • Cross-talk  between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells
    • PMID:18089848;
    • Chae HD, Lee KE, Williams DA, Gu Y. Cross-talk  between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells. Blood 2008; 111:2597-605; PMID:18089848; http://dx.doi.org/10.1182/blood-2007-06-093237
    • (2008) Blood , vol.111 , pp. 2597-2605
    • Chae, H.D.1    Lee, K.E.2    Williams, D.A.3    Gu, Y.4
  • 56
    • 4444240175 scopus 로고    scopus 로고
    • Wrch1 is a GTPase-deficient Cdc42-like protein with unusual binding characteristics and cellular effects
    • PMID:15350535;
    • Saras J, Wollberg P, Aspenstrom P. Wrch1 is a GTPase-deficient Cdc42-like protein with unusual binding characteristics and cellular effects. Exp Cell Res 2004; 299:356-69; PMID:15350535; http://dx.doi. org/10.1016/j.yexcr.2004.05.029
    • (2004) Exp Cell Res , vol.299 , pp. 356-369
    • Saras, J.1    Wollberg, P.2    Aspenstrom, P.3
  • 57
    • 9244239247 scopus 로고    scopus 로고
    • Atypical mechanism of regulation of the Wrch-1 Rho family small GTPase
    • PMID: 15556869;
    • Shutes A, Berzat AC, Cox AD, Der CJ. Atypical mechanism of regulation of the Wrch-1 Rho family small GTPase. Curr Biol 2004; 14:2052-6; PMID: 15556869; http://dx.doi.org/10.1016/j.cub.2004.11.011
    • (2004) Curr Biol , vol.14 , pp. 2052-2056
    • Shutes, A.1    Berzat, A.C.2    Cox, A.D.3    Der, C.J.4
  • 58
    • 32144458393 scopus 로고    scopus 로고
    • Biochemical analyses of the Wrch atypical Rho family GTPases
    • PMID:16472646;
    • Shutes A, Berzat AC, Chenette EJ, Cox AD, Der CJ. Biochemical analyses of the Wrch atypical Rho family GTPases. Methods Enzymol 2006; 406:11-26; PMID:16472646; http://dx.doi.org/10.1016/S00766879(06)06002-2
    • (2006) Methods Enzymol , vol.406 , pp. 11-26
    • Shutes, A.1    Berzat, A.C.2    Chenette, E.J.3    Cox, A.D.4    Der, C.J.5
  • 59
    • 36749082817 scopus 로고    scopus 로고
    • Identification of a bipartite focal adhesion localization signal in RhoU/Wrch-1, a Rho family GTPase that regulates cell adhesion and migration
    • PMID: 17620058;
    • Ory S, Brazier H, Blangy A. Identification of a bipartite focal adhesion localization signal in RhoU/Wrch-1, a Rho family GTPase that regulates cell adhesion and migration. Biol Cell 2007; 99:701-16; PMID: 17620058; http://dx.doi.org/10.1042/BC20070058
    • (2007) Biol Cell , vol.99 , pp. 701-716
    • Ory, S.1    Brazier, H.2    Blangy, A.3
  • 60
    • 34250830244 scopus 로고    scopus 로고
    • The atypical Rho family GTPase Wrch-1 regulates focal adhesion formation and cell migration
    • PMID:17504809;
    • Chuang YY, Valster A, Coniglio SJ, Backer JM, Symons M. The atypical Rho family GTPase Wrch-1 regulates focal adhesion formation and cell migration. J Cell Sci 2007; 120:1927-34; PMID:17504809; http:// dx.doi.org/10.1242/jcs.03456
    • (2007) J Cell Sci , vol.120 , pp. 1927-1934
    • Chuang, Y.Y.1    Valster, A.2    Coniglio, S.J.3    Backer, J.M.4    Symons, M.5
  • 62
    • 79151484190 scopus 로고    scopus 로고
    • Activity of the RhoU/Wrch1 GTPase is critical for cranial neural crest cell migration
    • PMID: 21156169;
    • Fort P, Guemar L, Vignal E, Morin N, Notarnicola C, de Santa Barbara P, Faure S. Activity of the RhoU/Wrch1 GTPase is critical for cranial neural crest cell migration. Dev Biol 2011; 350:451-63; PMID: 21156169; http://dx.doi.org/10.1016/j.ydbio.2010.12.011
    • (2011) Dev Biol , vol.350 , pp. 451-463
    • Fort, P.1    Guemar, L.2    Vignal, E.3    Morin, N.4    Notarnicola, C.5    De Santa Barbara, P.6    Faure, S.7
  • 63
    • 84255196942 scopus 로고    scopus 로고
    • Atypical RhoV and RhoU GTPases control development of the neural crest
    • PMID:22545228;
    • Faure S, Fort P. Atypical RhoV and RhoU GTPases control development of the neural crest. Small GTPases 2011; 2:310-3; PMID:22545228; http://dx.doi.org/10.4161/sgtp.18086
    • (2011) Small Gtpases , vol.2 , pp. 310-313
    • Faure, S.1    Fort, P.2
  • 64
    • 34250698385 scopus 로고    scopus 로고
    • Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp
    • PMID:17355222;
    • Weisz Hubsman M, Volinsky N, Manser E, Yablonski D, Aronheim A. Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp. Biochem J 2007; 404:487-97; PMID:17355222; http://dx.doi.org/10.1042/BJ20061696
    • (2007) Biochem J , vol.404 , pp. 487-497
    • Weisz Hubsman, M.1    Volinsky, N.2    Manser, E.3    Yablonski, D.4    Aronheim, A.5
  • 65
    • 0037145522 scopus 로고    scopus 로고
    • Genomic organization and expression profile of the small GTPases of the RhoBTB family in human and mouse
    • PMID: 12426103;
    • Ramos S, Khademi F, Somesh BP, Rivero F. Genomic organization and expression profile of the small GTPases of the RhoBTB family in human and mouse. Gene 2002; 298:147-57; PMID: 12426103; http://dx.doi.org/10.1016/S0378-1119(02)00980-0
    • (2002) Gene , vol.298 , pp. 147-157
    • Ramos, S.1    Khademi, F.2    Somesh, B.P.3    Rivero, F.4
  • 66
    • 34648844192 scopus 로고    scopus 로고
    • Taking Rho GTPases to the next level: The cellular functions of atypical Rho GTPases
    • PMID:17850788;
    • Aspenstrom P, Ruusala A, Pacholsky D. Taking Rho GTPases to the next level: the cellular functions of atypical Rho GTPases. Exp Cell Res 2007; 313:3673-9; PMID:17850788; http://dx.doi.org/10.1016/j.yexcr.2007.07.022
    • (2007) Exp Cell Res , vol.313 , pp. 3673-3679
    • Aspenstrom, P.1    Ruusala, A.2    Pacholsky, D.3
  • 68
    • 77954243855 scopus 로고    scopus 로고
    • Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions
    • PMID:20581838;
    • Connelly JT, Gautrot JE, Trappmann B, Tan DW, Donati G, Huck WT, Watt FM. Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions. Nat Cell Biol 2010; 12:711-8; PMID:20581838; http://dx.doi.org/10.1038/ncb2074
    • (2010) Nat Cell Biol , vol.12 , pp. 711-718
    • Connelly, J.T.1    Gautrot, J.E.2    Trappmann, B.3    Tan, D.W.4    Donati, G.5    Huck, W.T.6    Watt, F.M.7
  • 69
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • PMID:16923388;
    • Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell 2006; 126:677-89; PMID:16923388; http://dx.doi.org/10.1016/j.cell.2006.06.044
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 70
    • 81255149619 scopus 로고    scopus 로고
    • Mechanical stimuli differentially control stem cell behavior: Morphology, proliferation, and differentiation
    • PMID:21253809;
    • Maul TM, Chew DW, Nieponice A, Vorp DA. Mechanical stimuli differentially control stem cell behavior: morphology, proliferation, and differentiation. Biomech Model Mechanobiol 2011; 10:939-53; PMID:21253809; http://dx.doi.org/10.1007/s10237010-0285-8
    • (2011) Biomech Model Mechanobiol , vol.10 , pp. 939-953
    • Maul, T.M.1    Chew, D.W.2    Nieponice, A.3    Vorp, D.A.4
  • 71
    • 0344912596 scopus 로고    scopus 로고
    • Cell locomotion and focal adhesions are regulated by substrate flexibility
    • PMID:9391082;
    • Pelham RJ., Wang Yl. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc Natl Acad Sci U S A 1997; 94:13661-5; PMID:9391082; http://dx.doi.org/10.1073/ pnas.94.25.13661
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13661-13665
    • Pelham, R.J.1    Yl, W.2
  • 72
    • 79551484695 scopus 로고    scopus 로고
    • P190 RhoGTPase-activating protein links the b1 integrin/caveolin-1 mechanosignaling complex to RhoA and actin remodeling
    • PMID:21051664;
    • Yang B, Radel C, Hughes D, Kelemen S, Rizzo V. p190 RhoGTPase-activating protein links the b1 integrin/caveolin-1 mechanosignaling complex to RhoA and actin remodeling. Arterioscler Thromb Vasc Biol 2011; 31:376-83; PMID:21051664; http://dx.doi.org/10.1161/ATVBAHA.110.217794
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 376-383
    • Yang, B.1    Radel, C.2    Hughes, D.3    Kelemen, S.4    Rizzo, V.5
  • 73
  • 74
    • 80054043810 scopus 로고    scopus 로고
    • Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A
    • PMID:21926999;
    • Ehrlicher AJ, Nakamura F, Hartwig JH, Weitz DA, Stossel TP. Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A. Nature 2011; 478:260-3; PMID:21926999; http://dx.doi.org/10.1038/nature10430
    • (2011) Nature , vol.478 , pp. 260-263
    • Ehrlicher, A.J.1    Nakamura, F.2    Hartwig, J.H.3    Weitz, D.A.4    Stossel, T.P.5
  • 75
    • 33746658154 scopus 로고    scopus 로고
    • FilGAP, a Rhoand ROCK-regulated GAP for Rac binds filamin A to control actin remodelling
    • PMID:16862148;
    • Ohta Y, Hartwig JH, Stossel TP. FilGAP, a Rhoand ROCK-regulated GAP for Rac binds filamin A to control actin remodelling. Nat Cell Biol 2006; 8:803-14; PMID:16862148; http://dx.doi.org/10.1038/ncb1437
    • (2006) Nat Cell Biol , vol.8 , pp. 803-814
    • Ohta, Y.1    Hartwig, J.H.2    Stossel, T.P.3
  • 76
    • 65249182654 scopus 로고    scopus 로고
    • The role of FilGAP-filamin A interactions in mechanoprotection
    • PMID:19144823;
    • Shifrin Y, Arora PD, Ohta Y, Calderwood DA, McCul-loch CA. The role of FilGAP-filamin A interactions in mechanoprotection. Mol Biol Cell 2009; 20:1269-79; PMID:19144823; http://dx.doi.org/10.1091/mbc.E08-08-0872
    • (2009) Mol Biol Cell , vol.20 , pp. 1269-1279
    • Shifrin, Y.1    Arora, P.D.2    Ohta, Y.3    Calderwood, D.A.4    McCul-Loch, C.A.5
  • 78
    • 84884174451 scopus 로고    scopus 로고
    • Distinct signaling mechanisms regulate migration in unconfined versus confined spaces
    • PMID:23979717;
    • Hung WC, Chen SH, Paul CD, Stroka KM, Lo YC, Yang JT, Konstantopoulos K. Distinct signaling mechanisms regulate migration in unconfined versus confined spaces. J Cell Biol 2013; 202:807-24; PMID:23979717; http://dx.doi.org/10.1083/jcb.201302132
    • (2013) J Cell Biol , vol.202 , pp. 807-824
    • Hung, W.C.1    Chen, S.H.2    Paul, C.D.3    Stroka, K.M.4    Lo, Y.C.5    Yang, J.T.6    Konstantopoulos, K.7
  • 79
    • 84880331739 scopus 로고    scopus 로고
    • Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions
    • PMID:23792690;
    • Tozluoglu M, Tournier AL, Jenkins RP, Hooper S, Bates PA, Sahai E. Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions. Nat Cell Biol 2013; 15:751-62; PMID:23792690; http://dx.doi.org/10.1038/ncb2775
    • (2013) Nat Cell Biol , vol.15 , pp. 751-762
    • Tozluoglu, M.1    Tournier, A.L.2    Jenkins, R.P.3    Hooper, S.4    Bates, P.A.5    Sahai, E.6


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