Chronic alcohol ingestion in rats alters lung metabolism, promotes lipid accumulation, and impairs alveolar macrophage functions

American Journal of Respiratory Cell and Molecular Biology

Volumn 51, Issue 6, 2014, Pages 840-849

  Romero, Freddy ^a   Shah, Dilip ^a   Duong, Michelle ^a   Stafstrom, William ^a   Hoek, Jan B ^a   Kallen, Caleb B ^a   Lang, Charles H ^b   Summer, Ross ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

AMP activated protein kinase; Chronic alcohol ingestion; Macrophage; Surfactant lipids

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; TRIACYLGLYCEROL; ADENYLATE KINASE; ALCOHOL; ALCOHOL DEHYDROGENASE; CYTOCHROME P450 2E1; LIPOPOLYSACCHARIDE;

ALCOHOL CONSUMPTION; ALCOHOLIC FATTY LIVER; ALCOHOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ESSENTIAL GENE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LIPID HOMEOSTASIS; LIPID METABOLISM; LIPID STORAGE; LIPOGENESIS; LUNG ALVEOLUS MACROPHAGE; LUNG DISEASE; MALE; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; RAT; ADVERSE EFFECTS; ANIMAL; CELL POLARITY; DRINKING BEHAVIOR; DRUG EFFECTS; ENZYME ACTIVATION; IMMUNOLOGY; LUNG; METABOLISM; SPRAGUE DAWLEY RAT;

RATTUS;

ADENYLATE KINASE; ALCOHOL DEHYDROGENASE; ALCOHOL DRINKING; ANIMALS; CELL POLARITY; CYTOCHROME P-450 CYP2E1; ENZYME ACTIVATION; ETHANOL; LIPOGENESIS; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGES, ALVEOLAR; MALE; PHAGOCYTOSIS; RATS, SPRAGUE-DAWLEY; TRIGLYCERIDES;

EID: 84908379449     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2014-0127OC     Document Type: Article

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