Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus - Linking NMDA receptors and the reelin pathway

Experimental Neurology

Volumn 261, Issue , 2014, Pages 698-709

  Mota, Sandra I ^a,b   Ferreira, Ildete L ^a,b   Valero, Jorge ^a,b   Ferreiro, Elisabete ^a,b   Carvalho, Ana L ^a,b,c   Oliveira, Catarina R ^a,b,d   Rego, A Cristina ^a,b,d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

3xTg AD mice; Alzheimer's disease; Cortactin; Dab1; F actin; GluN2B subunits; Reelin; Src kinase

Indexed keywords

ACTIN; ADAPTOR PROTEIN; CORTACTIN; DAB1 PROTEIN; GLUN2A PROTEIN; GLUN2B PROTEIN; GLUTAMATE RECEPTOR 2; PHALLOIDIN; PROTEIN TYROSINE KINASE; REELIN; UNCLASSIFIED DRUG; AMYLOID PRECURSOR PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; NR2B NMDA RECEPTOR; PRESENILIN 1; PSEN1 PROTEIN, HUMAN; REELIN PROTEIN; SCLEROPROTEIN; SERINE PROTEINASE; TAU PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DEPOLYMERIZATION; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; MALE; NONHUMAN; PATHOGENESIS; POSTSYNAPTIC POTENTIAL; PROTEIN FUNCTION; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SUBUNIT; SIGNAL TRANSDUCTION; AGE; ANIMAL; DISEASE MODEL; GENETICS; HIPPOCAMPUS; HUMAN; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SEX DIFFERENCE; TRANSGENIC MOUSE;

ACTINS; AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL ADHESION MOLECULES, NEURONAL; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX PROTEINS; FEMALE; HIPPOCAMPUS; HUMANS; MALE; MICE; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; PHOSPHORYLATION; PRESENILIN-1; RECEPTORS, N-METHYL-D-ASPARTATE; SERINE ENDOPEPTIDASES; SEX FACTORS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TAU PROTEINS;

EID: 84908339906     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2014.07.023     Document Type: Article

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