메뉴 건너뛰기




Volumn 44, Issue 12, 2008, Pages 2019-2025

Gender and age-dependent differences in the mitochondrial apoptogenic pathway in Alzheimer's disease

Author keywords

Aging; Free radicals; Glutathione; Heme; Neurodegenerative disease

Indexed keywords

AMYLOID BETA PROTEIN; CYTOCHROME C;

EID: 43849091804     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.02.017     Document Type: Article
Times cited : (56)

References (29)
  • 1
    • 0026597063 scopus 로고
    • Alzheime's disease: the amyloid cascade hypothesis
    • Hardy J., and Higgins G.A. Alzheime's disease: the amyloid cascade hypothesis. Science 256 (1992) 184-185
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.1    Higgins, G.A.2
  • 4
    • 0031944692 scopus 로고    scopus 로고
    • Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo
    • Pappolla M.A., Chyan Y.J., Omar R.A., Hsiao K., Perry G., Smith M.A., and Bozner P. Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo. Am. J. Pathol. 152 (1998) 871-877
    • (1998) Am. J. Pathol. , vol.152 , pp. 871-877
    • Pappolla, M.A.1    Chyan, Y.J.2    Omar, R.A.3    Hsiao, K.4    Perry, G.5    Smith, M.A.6    Bozner, P.7
  • 5
    • 7244236841 scopus 로고    scopus 로고
    • A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide-the first step of a fatal cascade
    • Wirths O., Multhaup G., and Bayer T.A. A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide-the first step of a fatal cascade. J. Neurochem. 91 (2004) 513-520
    • (2004) J. Neurochem. , vol.91 , pp. 513-520
    • Wirths, O.1    Multhaup, G.2    Bayer, T.A.3
  • 6
    • 0037066072 scopus 로고    scopus 로고
    • Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease
    • Nagele R.G., D'Andrea M.R., Anderson W.J., and Wang H.Y. Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease. Neuroscience 110 (2002) 199-211
    • (2002) Neuroscience , vol.110 , pp. 199-211
    • Nagele, R.G.1    D'Andrea, M.R.2    Anderson, W.J.3    Wang, H.Y.4
  • 7
    • 0037192392 scopus 로고    scopus 로고
    • Induction of cytochrome c-mediated apoptosis by amyloid β 25-35 requires functional mitochondria
    • Cardoso S.M., Swerdlow H., and Oliveira C.R. Induction of cytochrome c-mediated apoptosis by amyloid β 25-35 requires functional mitochondria. Brain Res. 931 (2002) 117-125
    • (2002) Brain Res. , vol.931 , pp. 117-125
    • Cardoso, S.M.1    Swerdlow, H.2    Oliveira, C.R.3
  • 8
    • 0035378322 scopus 로고    scopus 로고
    • Functional mitochondria are required for amyloid beta-mediated
    • Cardoso S.M., Santos S., Swerdlow R.H., and Oliveira C.R. Functional mitochondria are required for amyloid beta-mediated. FASEB J. 15 (2001) 1439-1441
    • (2001) FASEB J. , vol.15 , pp. 1439-1441
    • Cardoso, S.M.1    Santos, S.2    Swerdlow, R.H.3    Oliveira, C.R.4
  • 9
    • 33748466130 scopus 로고    scopus 로고
    • Apoptosis in Alzheimer disease: a mathematical improbability
    • Zhu X., Raina A.K., Perry G., and Smith M.A. Apoptosis in Alzheimer disease: a mathematical improbability. Curr. Alzheimer Res. 3 (2006) 393-396
    • (2006) Curr. Alzheimer Res. , vol.3 , pp. 393-396
    • Zhu, X.1    Raina, A.K.2    Perry, G.3    Smith, M.A.4
  • 11
    • 0037373449 scopus 로고    scopus 로고
    • Mitochondria from females exhibit higher antioxidant gene expression and cover oxidative damage than males
    • Borras C., Sastre J., Garcia-Sala D., Lloret A., Pallardó F.V., and Viña J. Mitochondria from females exhibit higher antioxidant gene expression and cover oxidative damage than males. Free Radic. Biol. Med. 34 (2003) 546-552
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 546-552
    • Borras, C.1    Sastre, J.2    Garcia-Sala, D.3    Lloret, A.4    Pallardó, F.V.5    Viña, J.6
  • 12
    • 3342880690 scopus 로고    scopus 로고
    • A role for heme in Alzheimer's disease: heme binds amyloid beta and has altered metabolism
    • Atamna H., and Frey W.H. A role for heme in Alzheimer's disease: heme binds amyloid beta and has altered metabolism. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 11153-11158
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 11153-11158
    • Atamna, H.1    Frey, W.H.2
  • 13
    • 33644778691 scopus 로고    scopus 로고
    • Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease
    • Atamna H., and Boyle K. Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 3381-3386
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 3381-3386
    • Atamna, H.1    Boyle, K.2
  • 15
    • 10644290831 scopus 로고    scopus 로고
    • Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells
    • Esposito L., Gan L., Yu G.Q., Essrich C., and Mucke L. Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells. J. Neurochem. 91 (2004) 1260-1274
    • (2004) J. Neurochem. , vol.91 , pp. 1260-1274
    • Esposito, L.1    Gan, L.2    Yu, G.Q.3    Essrich, C.4    Mucke, L.5
  • 16
    • 4344620045 scopus 로고    scopus 로고
    • Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide
    • Lebeau A., Terro F., Rostene W., and Pelaprat D. Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide. Cell Death Differ. 11 (2004) 875-884
    • (2004) Cell Death Differ. , vol.11 , pp. 875-884
    • Lebeau, A.1    Terro, F.2    Rostene, W.3    Pelaprat, D.4
  • 18
    • 0030896414 scopus 로고    scopus 로고
    • Isolation and culture of adult rat hippocampal neurons
    • Brewer G.J. Isolation and culture of adult rat hippocampal neurons. J. Neurosci. Methods 71 (1997) 143-155
    • (1997) J. Neurosci. Methods , vol.71 , pp. 143-155
    • Brewer, G.J.1
  • 19
    • 0032439245 scopus 로고    scopus 로고
    • Mitochondrial free radical production and aging in mammals and birds
    • Barja G. Mitochondrial free radical production and aging in mammals and birds. Ann. N. Y. Acad. Sci. 854 (1998) 224-238
    • (1998) Ann. N. Y. Acad. Sci. , vol.854 , pp. 224-238
    • Barja, G.1
  • 22
    • 27544484846 scopus 로고    scopus 로고
    • Are mitochondria critical in the pathogenesis of Alzheimer's disease?
    • Reddy P.H., and Beal M.F. Are mitochondria critical in the pathogenesis of Alzheimer's disease?. Brain Res. Rev. 49 (2005) 618-632
    • (2005) Brain Res. Rev. , vol.49 , pp. 618-632
    • Reddy, P.H.1    Beal, M.F.2
  • 23
    • 23844445847 scopus 로고    scopus 로고
    • 17beta-oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NFkappaB cascade
    • Borras C., Gambini J., Gomez-Cabrera M.C., Sastre J., Pallardo F.V., Mann G.E., and Vina J. 17beta-oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NFkappaB cascade. Aging Cell 4 (2005) 113-118
    • (2005) Aging Cell , vol.4 , pp. 113-118
    • Borras, C.1    Gambini, J.2    Gomez-Cabrera, M.C.3    Sastre, J.4    Pallardo, F.V.5    Mann, G.E.6    Vina, J.7
  • 24
    • 33751201263 scopus 로고    scopus 로고
    • Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function
    • Nilsen J., Chen S., Irwin R.W., Iwamoto S., and Brinton R.D. Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function. BMC Neurosci. 7 (2006) 74-79
    • (2006) BMC Neurosci. , vol.7 , pp. 74-79
    • Nilsen, J.1    Chen, S.2    Irwin, R.W.3    Iwamoto, S.4    Brinton, R.D.5
  • 25
    • 33847032137 scopus 로고    scopus 로고
    • Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death
    • Yao M., Nguyen T.V., and Pike C.J. Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death. J. Neurosci. 27 (2007) 1422-1433
    • (2007) J. Neurosci. , vol.27 , pp. 1422-1433
    • Yao, M.1    Nguyen, T.V.2    Pike, C.J.3
  • 27
    • 0035925762 scopus 로고    scopus 로고
    • Hormone replacement therapy and cognition: systematic review and meta-analysis
    • LeBlanc E.S., Janowsky J., Chan B.K., and Nelson H.D. Hormone replacement therapy and cognition: systematic review and meta-analysis. JAMA 285 (2001) 1489-1499
    • (2001) JAMA , vol.285 , pp. 1489-1499
    • LeBlanc, E.S.1    Janowsky, J.2    Chan, B.K.3    Nelson, H.D.4
  • 28
    • 0031695197 scopus 로고    scopus 로고
    • Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
    • Brookmeyer R., Gray S., and Kawas C. Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am. J. Public Health 88 (1998) 1337-1342
    • (1998) Am. J. Public Health , vol.88 , pp. 1337-1342
    • Brookmeyer, R.1    Gray, S.2    Kawas, C.3
  • 29
    • 33751103136 scopus 로고    scopus 로고
    • Heme binding to Amyloid-beta peptide: mechanistic role in Alzheimer's disease
    • Atamna H. Heme binding to Amyloid-beta peptide: mechanistic role in Alzheimer's disease. J. Alzheimers Dis. 10 (2006) 255-2566
    • (2006) J. Alzheimers Dis. , vol.10 , pp. 255-2566
    • Atamna, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.