Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL

Journal of Experimental Medicine

Volumn 208, Issue 4, 2011, Pages 663-675

  Li, Xiaoyu ^a   Sanda, Takaomi ^a   Thomas Look, A ^a   Novina, Carl D ^a   von Boehmer, Harald ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; MESSENGER RNA; MICRORNA 451; MICRORNA 709; MYC PROTEIN; NOTCH1 RECEPTOR; PROTEIN KINASE B; TRANSCRIPTION FACTOR E2A; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; LEUKEMIA; LEUKEMOGENESIS; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; T CELL ACUTE LYMPHOBLASTIC LEUKEMIA; THYMOCYTE; UPREGULATION; WILD TYPE;

ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; GENES, MYC; GENES, RAS; HUMANS; MICE; MICE, INBRED BALB C; MICRORNAS; MOLECULAR SEQUENCE DATA; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, NOTCH1;

EID: 79955756373     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20102384     Document Type: Article

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