Aberrant production of Th1/Th2/Th17-related cytokines in serum of C57bl/6 mice after short-term formaldehyde exposure

International Journal of Environmental Research and Public Health

Volumn 11, Issue 10, 2014, Pages 10036-10050

  Wei, Haiyan ^a   Tan, Kehong ^a   Sun, Rongli ^a   Yin, Lihong ^a   Zhang, Juan ^a   Pu, Yuepu ^a  

^a SOUTHEAST UNIVERSITY   (China)

Author keywords

Cytokine; Cytometric bead array; Flow cytometer; Formaldehyde; Serum

Indexed keywords

CYTOKINE; FORMALDEHYDE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR; DANGEROUS GOODS;

FLOW CYTOMETRY; FORMALDEHYDE; IMMUNE SYSTEM; PROTEIN; RODENT; SERUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMETRIC BEAD ARRAY; CYTOMETRY; EXPOSURE; FLOW CYTOMETRY; MALE; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; TH1 CELL; TH17 CELL; TH2 CELL; ANIMAL; BLOOD; C57BL MOUSE; DANGEROUS GOODS; DRUG EFFECTS; HELPER CELL; IMMUNOLOGY; PROCEDURES; TOXICITY;

MUS;

ANIMALS; CYTOKINES; FLOW CYTOMETRY; FORMALDEHYDE; HAZARDOUS SUBSTANCES; MALE; MICE; MICE, INBRED C57BL; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84908322788     PISSN: 16617827     EISSN: 16604601     Source Type: Journal    
DOI: 10.3390/ijerph111010036     Document Type: Article

References (56)

1. 1. Syamlal, G.; Mazurek, J.M.; Bang, K.M. Prevalence of lifetime asthma and current asthma attacks in U.S. Working adults: An analysis of the 1997–2004 national health interview survey data. J. Occup. Environ. Med. 2009, 51, 1066–1074.
2. 2. Liu, D.; Zheng, Y.; Li, B.; Yao, H.; Li, R.; Zhang, Y.; Yang, X. Adjuvant effects of gaseous formaldehyde on the hyper-responsiveness and inflammation in a mouse asthma model immunized by ovalbumin. J. Immunotoxicol. 2011, 8, 305–314.
3. 3. Hosgood, H.D.; Zhang, L.; Tang, X.; Vermeulen, R.; Hao, Z.; Shen, M.; Qiu, C.; Ge, Y.; Hua, M.; Ji, Z., et al. Occupational exposure to formaldehyde and alterations in lymphocyte subsets. Amer. J. Ind. Med. 2013, 56, 252–257.
4. 4. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Formaldehyde, 2-butoxyethanol and 1-tert-butoxypropan-2-ol. IARC Monogr. Eval. Carcinog. Risks Hum. 2006, 88, 1–287.
5. 5. Coggon, D.; Harris, E.C.; Poole, J.; Palmer, K.T. Extended follow-up of a cohort of British chemical workers exposed to formaldehyde. J. Natl. Cancer Instit. 2003, 95, 1608–1615.
6. 6. Hauptmann, M.; Lubin, J.H.; Stewart, P.A.; Hayes, R.B.; Blair, A. Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries. J. Natl. Cancer Instit. 2003, 95, 1615–1623.
7. 7. Hauptmann, M.; Lubin, J.H.; Stewart, P.A.; Hayes, R.B.; Blair, A. Mortality from solid cancers among workers in formaldehyde industries. Amer. J. Epidemiol. 2004, 159, 1117–1130.
8. 8. IARC monographs on the evaluation of carcinogenic risks to humans. Chemical agents and related occupations. IARC Monogr. Eval. Carcinog. Risks Hum. 2012, 100, 9–562.
9. 9. Sandikci, M.; Eren, U.; Kum, S. Effects of formaldehyde and xylene on cd4- and cd8-positive T cells in bronchus-associated lymphoid tissue in rats. Toxicol. Ind. Health 2007, 23, 471–477.
10. 10. Aydin, S.; Canpinar, H.; Undeger, U.; Guc, D.; Colakoglu, M.; Kars, A.; Basaran, N. Assessment of immunotoxicity and genotoxicity in workers exposed to low concentrations of formaldehyde. Arch. Toxicol. 2013, 87, 145–153.
11. 11. Zhang, L.; Tang, X.; Rothman, N.; Vermeulen, R.; Ji, Z.; Shen, M.; Qiu, C.; Guo, W.; Liu, S.; Reiss, B., et al. Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells. Cancer Epidemiol. Biomark. Prev. 2010, 19, 80–88.
12. 12. Lee, C.G.; Sahoo, A.; Im, S.H. Epigenetic regulation of cytokine gene expression in T lymphocytes. Yonsei Med. J.2009, 50, 322–330.
13. 13. Ohtsuka, R.; Shutoh, Y.; Fujie, H.; Yamaguchi, S.; Takeda, M.; Harada, T.; Doi, K. Rat strain difference in histology and expression of Th1- and Th2-related cytokines in nasal mucosa after short-term formaldehyde inhalation. Exp. Toxicol. Pathol. 2003, 54, 287–291.
14. 14. Jimenez, R.; Ramirez, R.; Carracedo, J.; Aguera, M.; Navarro, D.; Santamaria, R.; Perez, R.; del Castillo, D.; Aljama, P. Cytometric bead array (CBA) for the measurement of cytokines in urine and plasma of patients undergoing renal rejection. Cytokine 2005, 32, 45–50.
15. 15. Wyns, H.; Croubels, S.; Demeyere, K.; Watteyn, A.; de Backer, P.; Meyer, E. Development of a cytometric bead array screening tool for the simultaneous detection of pro-inflammatory cytokines in porcine plasma. Vet. Immunol. Immunopathol. 2013, 151, 28–36.
16. 16. Ulrich, P.; Grenet, O.; Bluemel, J.; Vohr, H.W.; Wiemann, C.; Grundler, O.; Suter, W. Cytokine expression profiles during murine contact allergy: T helper 2 cytokines are expressed irrespective of the type of contact allergen. Arch. Toxicol.2001, 75, 470–479.
17. 17. Fujimaki, H.; Kurokawa, Y.; Kunugita, N.; Kikuchi, M.; Sato, F.; Arashidani, K. Differential immunogenic and neurogenic inflammatory responses in an allergic mouse model exposed to low levels of formaldehyde. Toxicology 2004, 197, 1–13.
18. 18. Wang, F.; Li, C.; Liu, W.; Jin, Y. Effect of exposure to volatile organic compounds (VOCs) on airway inflammatory response in mice. J. Toxicol. Sci.2012, 37, 739–748.
19. 19. Kim, J.Y.; Jeong, M.S.; Park, K.Y.; Seo, S.J. Aggravation of atopic dermatitis-like symptoms by consecutive low concentration of formaldehyde exposure in NC/NGA mice. Exp. Dermatol.2013, 22, 219–221.
20. 20. Thrasher, J.D.; Broughton, A.; Madison, R. Immune activation and autoantibodies in humans with long-term inhalation exposure to formaldehyde. Arch. Environ. Health 1990, 45, 217–223.
21. 21. Persoz, C.; Achard, S.; Momas, I.; Seta, N. Inflammatory response modulation of airway epithelial cells exposed to formaldehyde. Toxicol Lett. 2012, 211, 159–163.
22. 22. Kastner, P.E.; le Calve, S.; Zheng, W.; Casset, A.; Pons, F. A dynamic system for single and repeated exposure of airway epithelial cells to gaseous pollutants. Toxicol. In Vitro 2013, 27, 632–640.
23. 23. Bardet, G.; Achard, S.; Loret, T.; Desauziers, V.; Momas, I.; Seta, N. A model of human nasal epithelial cells adapted for direct and repeated exposure to airborne pollutants. Toxicol. Lett. 2014, 229, 144–149.
24. 24. Rager, J.E.; Smeester, L.; Jaspers, I.; Sexton, K.G.; Fry, R.C. Epigenetic changes induced by air toxics: Formaldehyde exposure alters mirna expression profiles in human lung cells. Environ. Health Perspect. 2011, 119, 494–500.
25. Zhang, Y.; Liu, X.; McHale, C.; Li, R.; Zhang, L.; Wu, Y.; Ye, X.; Yang, X.; Ding, S. Bone marrow injury induced via oxidative stress in mice by inhalation exposure to formaldehyde. PLoS One 2013, 8, doi:10.1371/journal.pone.0074974.
26. 26. Larsen, S.T.; Wolkoff, P.; Hammer, M.; Kofoed-Sorensen, V.; Clausen, P.A.; Nielsen, G.D. Acute airway effects of airborne formaldehyde in sensitized and non-sensitized mice housed in a dry or humid environment. Toxicol. Appl. Pharmacol. 2013, 268, 294–299.
27. 27. Lino dos Santos Franco, A.; Domingos, H.V.; Damazo, A.S.; Breithaupt-Faloppa, A.C.; de Oliveira, A.P.; Costa, S.K.; Oliani, S.M.; Oliveira-Filho, R.M.; Vargaftig, B.B.; Tavares-de-Lima, W. Reduced allergic lung inflammation in rats following formaldehyde exposure: Long-term effects on multiple effector systems. Toxicology 2009, 256, 157–163.
28. 28. Casset, A.; Marchand, C.; Purohit, A.; le Calve, S.; Uring-Lambert, B.; Donnay, C.; Meyer, P.; de Blay, F. Inhaled formaldehyde exposure: Effect on bronchial response to mite allergen in sensitized asthma patients. Allergy 2006, 61, 1344–1350.
29. 29. Frank, J.W.; Carroll, J.A.; Allee, G.L.; Zannelli, M.E. The effects of thermal environment and spray-dried plasma on the acute-phase response of pigs challenged with lipopolysaccharide. J. Anim. Sci. 2003, 81, 1166–1176.
30. 30. Elshal, M.F.; McCoy, J.P. Multiplex bead array assays: Performance evaluation and comparison of sensitivity to ELISA. Methods 2006, 38, 317–323.
31. 31. Williams, P.N.; Collier, C.T.; Carroll, J.A.; Welsh, T.H., Jr.; Laurenz, J.C. Temporal pattern and effect of sex on lipopolysaccharide-induced stress hormone and cytokine response in pigs. Domest. Anim. Endocrinol. 2009, 37, 139–147.
32. 32. Williams, A.; Steffens, F.; Reinecke, C.; Meyer, D. The Th1/Th2/Th17 cytokine profile of HIV-infected individuals: A multivariate cytokinomics approach. Cytokine 2013, 61, 521–526.
33. 33. Yujie, W.; Yu, Z.; Sixuan, Q.; Li, W.; Peng, L.; Zeng, G.; Sujiang, Z.; Jianyong, L. Detection of bcr-abl fusion proteins in patients with leukemia using a cytometric bead array. Leuk. Lymphoma 2012, 53, 451–455.
34. 34. Talat, N.; Shahid, F.; Perry, S.; Dawood, G.; Hussain, R. Th1/th2 cytometric bead array can discriminate cytokine secretion from endogenously activated cells in pulmonary disease, recent and remote infection in tuberculosis. Cytokine 2011, 54, 136–143.
35. 35. Sadakane, K.; Takano, H.; Ichinose, T.; Yanagisawa, R.; Shibamoto, T. Formaldehyde enhances mite allergen-induced eosinophilic inflammation in the murine airway. J. Environ. Pathol. Toxicol. Oncol. 2002, 21, 267–276.
36. 36. Nandate, K.; Ishidao, T.; Hori, H.; Morimoto, Y.; Ogata, M. The effect of formaldehyde exposure on cytokine production in murine alveolar macrophages. J. UOEH 2003, 25, 197–205.
37. 37. Thrasher, J.D.; Wojdani, A.; Cheung, G.; Heuser, G. Evidence for formaldehyde antibodies and altered cellular immunity in subjects exposed to formaldehyde in mobile homes. Arch. Environ. Health 1987, 42, 347–350.
38. 38. Tarkowski, M.; Kur, B.; Polakowska, E.; Jablonska, E. Comparative studies of lymph node cell subpopulations and cytokine expression in murine model for testing the potentials of chemicals to induce respiratory sensitization. Int. J. Occupational Med. Environ. Health 2008, 21, 253–262.
39. 39. Sasaki, Y.; Ohtani, T.; Ito, Y.; Mizuashi, M.; Nakagawa, S.; Furukawa, T.; Horii, A.; Aiba, S. Molecular events in human T cells treated with diesel exhaust particles or formaldehyde that underlie their diminished interferon-gamma and interleukin-10 production. Int. Arch. Allergy Immunol. 2009, 148, 239–250.
40. 40. Hoyer, K.K.; Dooms, H.; Barron, L.; Abbas, A.K. Interleukin-2 in the development and control of inflammatory disease. Immunol. Rev. 2008, 226, 19–28.
41. 41. Hofmann, S.R.; Ettinger, R.; Zhou, Y.J.; Gadina, M.; Lipsky, P.; Siegel, R.; Candotti, F.; O’Shea, J.J. Cytokines and their role in lymphoid development, differentiation and homeostasis. Curr. Opin. Allergy Clin. Immunol. 2002, 2, 495–506.
42. 42. Jones, S.A. Directing transition from innate to acquired immunity: Defining a role for IL-6. J. Immunol. 2005, 175, 3463–3468.
43. 43. Huang, M.; Wang, J.; Lee, P.; Sharma, S.; Mao, J.T.; Meissner, H.; Uyemura, K.; Modlin, R.; Wollman, J.; Dubinett, S.M. Human non-small cell lung cancer cells express a type 2 cytokine pattern. Cancer Res. 1995, 55, 3847–3853.
44. 44. Mills, K.H. Induction, function and regulation of IL-17-producing T cells. Eur. J. Immunol. 2008, 38, 2636–2649.
45. 45. Weaver, C.T.; Hatton, R.D.; Mangan, P.R.; Harrington, L.E. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 2007, 25, 821–852.
46. 46. Cousens, L.P.; Orange, J.S.; Biron, C.A. Endogenous IL-2 contributes to t cell expansion and ifn-gamma production during lymphocytic choriomeningitis virus infection. J. Immunol. 1995, 155, 5690–5699.
47. 47. Dallman, M.J.; Wood, K.J.; Hamano, K.; Bushell, A.R.; Morris, P.J.; Wood, M.J.; Charlton, H.M. Cytokines and peripheral tolerance to alloantigen. Immunol. Rev. 1993, 133, 5–18.
48. 48. Dallman, M.J. Cytokines as mediators of organ graft rejection and tolerance. Curr. Opin. Immunol. 1993, 5, 788–793.
49. 49. Ezratty, V.; Bonay, M.; Neukirch, C.; Orset-Guillossou, G.; Dehoux, M.; Koscielny, S.; Cabanes, P.A.; Lambrozo, J.; Aubier, M. Effect of formaldehyde on asthmatic response to inhaled allergen challenge. Environ. Health Perspect. 2007, 115, 210–214.
50. 50. Moser, B.; Bodrogi, F.; Eibl, G.; Lechner, M.; Rieder, J.; Lirk, P. Mass spectrometric profile of exhaled breath—Field study by PTR-MS. Respir. Physiol. Neurobiol. 2005, 145, 295–300.
51. 51. Sibirny, V.; Demkiv, O.; Klepach, H.; Honchar, T.; Gonchar, M. Alcohol oxidase- and formaldehyde dehydrogenase-based enzymatic methods for formaldehyde assay in fish food products. Food Chem. 2011, 127, 774–779.
52. 52. Kim, E.M.; Lee, H.Y.; Lee, E.H.; Lee, K.M.; Park, M.; Ji, K.Y.; Jang, J.H.; Jeong, Y.H.; Lee, K.H.; Yoon, I.J., et al. Formaldehyde exposure impairs the function and differentiation of NK cells. Toxicol. Lett. 2013, 223, 154–161.
53. 53. Intlekofer, A.M.; Takemoto, N.; Wherry, E.J.; Longworth, S.A.; Northrup, J.T.; Palanivel, V.R.; Mullen, A.C.; Gasink, C.R.; Kaech, S.M.; Miller, J.D., et al. Effector and memory cd8+ T cell fate coupled by T-bet and eomesodermin. Nat. Immunol. 2005, 6, 1236–1244.
54. 54. Witowski, J.; Wisniewska, J.; Korybalska, K.; Bender, T.O.; Breborowicz, A.; Gahl, G.M.; Frei, U.; Passlick-Deetjen, J.; Jorres, A. Prolonged exposure to glucose degradation products impairs viability and function of human peritoneal mesothelial cells. J. Amer. Soc. Nephrol. 2001, 12, 2434–2441.
55. 55. Kitagaki, H.; Ono, N.; Hayakawa, K.; Kitazawa, T.; Watanabe, K.; Shiohara, T. Repeated elicitation of contact hypersensitivity induces a shift in cutaneous cytokine milieu from a T helper cell type 1 to a T helper cell type 2 profile. J. Immunol. 1997, 159, 2484–2491.
56. 56. Kitagaki, H.; Kimishima, M.; Teraki, Y.; Hayakawa, J.; Hayakawa, K.; Fujisawa, S.; Shiohara, T. Distinct in vivo and in vitro cytokine profiles of draining lymph node cells in acute and chronic phases of contact hypersensitivity: Importance of a type 2 cytokine-rich cutaneous milieu for the development of an early-type response in the chronic phase. J. Immunol. 1999, 163, 1265–1273.